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Volumn 33, Issue 24, 2014, Pages 2997-3011

Arhgef7 promotes activation of the Hippo pathway core kinase Lats

Author keywords

Arhgef7; Hippo; Lats; mechanotransduction; Yap Taz

Indexed keywords

ARHGEF PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HIPPO KINASE; LATS1 PROTIEN; PHOSPHOTRANSFERASE; PROTEIN; TAZ PROTEIN; UNCLASSIFIED DRUG; YAP PROTEIN; ARHGEF7 PROTEIN, HUMAN; LATS1 PROTEIN, HUMAN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAZ PROTEIN, HUMAN; TRANSCRIPTION FACTOR; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

EID: 84918829195     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201490230     Document Type: Article
Times cited : (31)

References (61)
  • 1
    • 84880055491 scopus 로고    scopus 로고
    • Signal integration in TGF-beta, WNT, and Hippo pathways
    • Attisano L, Wrana JL, (2013) Signal integration in TGF-beta, WNT, and Hippo pathways. F1000Prime Rep 5: 17
    • (2013) F1000Prime Rep , vol.5 , pp. 17
    • Attisano, L.1    Wrana, J.L.2
  • 3
    • 84868695821 scopus 로고    scopus 로고
    • Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells
    • Bao R, Christova T, Song S, Angers S, Yan X, Attisano L, (2012) Inhibition of tankyrases induces Axin stabilization and blocks Wnt signalling in breast cancer cells. PLoS ONE 7: e48670
    • (2012) PLoS ONE , vol.7 , pp. e48670
    • Bao, R.1    Christova, T.2    Song, S.3    Angers, S.4    Yan, X.5    Attisano, L.6
  • 5
    • 84859852225 scopus 로고    scopus 로고
    • Growth control by committee: Intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling
    • Boggiano JC, Fehon RG, (2012) Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling. Dev Cell 22: 695-702
    • (2012) Dev Cell , vol.22 , pp. 695-702
    • Boggiano, J.C.1    Fehon, R.G.2
  • 6
    • 48749118026 scopus 로고    scopus 로고
    • Endothelin-1 couples betaPix to p66Shc: Role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of Akt
    • Chahdi A, Sorokin A, (2008) Endothelin-1 couples betaPix to p66Shc: role of betaPix in cell proliferation through FOXO3a phosphorylation and p27kip1 down-regulation independently of Akt. Mol Biol Cell 19: 2609-2619
    • (2008) Mol Biol Cell , vol.19 , pp. 2609-2619
    • Chahdi, A.1    Sorokin, A.2
  • 13
    • 0141753108 scopus 로고    scopus 로고
    • The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins
    • Flanders JA, Feng Q, Bagrodia S, Laux MT, Singavarapu A, Cerione RA, (2003) The Cbl proteins are binding partners for the Cool/Pix family of p21-activated kinase-binding proteins. FEBS Lett 550: 119-123
    • (2003) FEBS Lett , vol.550 , pp. 119-123
    • Flanders, J.A.1    Feng, Q.2    Bagrodia, S.3    Laux, M.T.4    Singavarapu, A.5    Cerione, R.A.6
  • 14
    • 79956046567 scopus 로고    scopus 로고
    • The Hippo pathway and apico-basal cell polarity
    • Genevet A, Tapon N, (2011) The Hippo pathway and apico-basal cell polarity. Biochem J 436: 213-224
    • (2011) Biochem J , vol.436 , pp. 213-224
    • Genevet, A.1    Tapon, N.2
  • 15
    • 77950485564 scopus 로고    scopus 로고
    • Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms
    • Grzeschik NA, Parsons LM, Allott ML, Harvey KF, Richardson HE, (2010) Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. Curr Biol 20: 573-581
    • (2010) Curr Biol , vol.20 , pp. 573-581
    • Grzeschik, N.A.1    Parsons, L.M.2    Allott, M.L.3    Harvey, K.F.4    Richardson, H.E.5
  • 16
    • 78650724753 scopus 로고    scopus 로고
    • Hippo signaling: Growth control and beyond
    • Halder G, Johnson RL, (2011) Hippo signaling: growth control and beyond. Development 138: 9-22
    • (2011) Development , vol.138 , pp. 9-22
    • Halder, G.1    Johnson, R.L.2
  • 17
    • 84865411430 scopus 로고    scopus 로고
    • Transduction of mechanical and cytoskeletal cues by YAP and TAZ
    • Halder G, Dupont S, Piccolo S, (2012) Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol 13: 591-600
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 591-600
    • Halder, G.1    Dupont, S.2    Piccolo, S.3
  • 19
    • 84900424727 scopus 로고    scopus 로고
    • The transcriptional regulators TAZ and YAP direct transforming growth factor beta-induced tumorigenic phenotypes in breast cancer cells
    • Hiemer SE, Szymaniak AD, Varelas X, (2014) The transcriptional regulators TAZ and YAP direct transforming growth factor beta-induced tumorigenic phenotypes in breast cancer cells. J Biol Chem 289: 13461-13474
    • (2014) J Biol Chem , vol.289 , pp. 13461-13474
    • Hiemer, S.E.1    Szymaniak, A.D.2    Varelas, X.3
  • 20
    • 33646705915 scopus 로고    scopus 로고
    • The multifunctional GIT family of proteins
    • Hoefen RJ, Berk BC, (2006) The multifunctional GIT family of proteins. J Cell Sci 119: 1469-1475
    • (2006) J Cell Sci , vol.119 , pp. 1469-1475
    • Hoefen, R.J.1    Berk, B.C.2
  • 22
    • 84866622306 scopus 로고    scopus 로고
    • Integration of intercellular signaling through the Hippo pathway
    • Irvine KD, (2012) Integration of intercellular signaling through the Hippo pathway. Semin Cell Dev Biol 23: 812-817
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 812-817
    • Irvine, K.D.1
  • 25
    • 0035815617 scopus 로고    scopus 로고
    • Leucine zipper-mediated homodimerization of the p21-activated kinase-interacting factor, beta Pix. Implication for a role in cytoskeletal reorganization
    • Kim S, Lee SH, Park D, (2001) Leucine zipper-mediated homodimerization of the p21-activated kinase-interacting factor, beta Pix. Implication for a role in cytoskeletal reorganization. J Biol Chem 276: 10581-10584
    • (2001) J Biol Chem , vol.276 , pp. 10581-10584
    • Kim, S.1    Lee, S.H.2    Park, D.3
  • 26
    • 79961087833 scopus 로고    scopus 로고
    • E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components
    • Kim NG, Koh E, Chen X, Gumbiner BM, (2011) E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. Proc Natl Acad Sci U S A 108: 11930-11935
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11930-11935
    • Kim, N.G.1    Koh, E.2    Chen, X.3    Gumbiner, B.M.4
  • 27
    • 84878547831 scopus 로고    scopus 로고
    • CAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes
    • Kim M, Kim M, Lee S, Kuninaka S, Saya H, Lee H, Lee S, Lim DS, (2013) cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes. EMBO J 32: 1543-1555
    • (2013) EMBO J , vol.32 , pp. 1543-1555
    • Kim, M.1    Kim, M.2    Lee, S.3    Kuninaka, S.4    Saya, H.5    Lee, H.6    Lee, S.7    Lim, D.S.8
  • 29
    • 0034682515 scopus 로고    scopus 로고
    • Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways
    • Labbe E, Letamendia A, Attisano L, (2000) Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways. Proc Natl Acad Sci U S A 97: 8358-8363
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 8358-8363
    • Labbe, E.1    Letamendia, A.2    Attisano, L.3
  • 31
    • 41149098966 scopus 로고    scopus 로고
    • TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway
    • Lei QY, Zhang H, Zhao B, Zha ZY, Bai F, Pei XH, Zhao S, Xiong Y, Guan KL, (2008) TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway. Mol Cell Biol 28: 2426-2436
    • (2008) Mol Cell Biol , vol.28 , pp. 2426-2436
    • Lei, Q.Y.1    Zhang, H.2    Zhao, B.3    Zha, Z.Y.4    Bai, F.5    Pei, X.H.6    Zhao, S.7    Xiong, Y.8    Guan, K.L.9
  • 32
    • 77953738883 scopus 로고    scopus 로고
    • The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded
    • Ling C, Zheng Y, Yin F, Yu J, Huang J, Hong Y, Wu S, Pan D, (2010) The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded. Proc Natl Acad Sci U S A 107: 10532-10537
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10532-10537
    • Ling, C.1    Zheng, Y.2    Yin, F.3    Yu, J.4    Huang, J.5    Hong, Y.6    Wu, S.7    Pan, D.8
  • 35
  • 37
    • 44349127316 scopus 로고    scopus 로고
    • AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling
    • Missy K, Hu B, Schilling K, Harenberg A, Sakk V, Kuchenbecker K, Kutsche K, Fischer KD, (2008) AlphaPIX Rho GTPase guanine nucleotide exchange factor regulates lymphocyte functions and antigen receptor signaling. Mol Cell Biol 28: 3776-3789
    • (2008) Mol Cell Biol , vol.28 , pp. 3776-3789
    • Missy, K.1    Hu, B.2    Schilling, K.3    Harenberg, A.4    Sakk, V.5    Kuchenbecker, K.6    Kutsche, K.7    Fischer, K.D.8
  • 38
    • 60849138138 scopus 로고    scopus 로고
    • Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling
    • Ota M, Sasaki H, (2008) Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling. Development 135: 4059-4069
    • (2008) Development , vol.135 , pp. 4059-4069
    • Ota, M.1    Sasaki, H.2
  • 40
    • 84862764408 scopus 로고    scopus 로고
    • The Hippo signaling pathway and stem cell biology
    • Ramos A, Camargo FD, (2012) The Hippo signaling pathway and stem cell biology. Trends Cell Biol 22: 339-346
    • (2012) Trends Cell Biol , vol.22 , pp. 339-346
    • Ramos, A.1    Camargo, F.D.2
  • 41
    • 84875263231 scopus 로고    scopus 로고
    • Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins
    • Reddy BV, Irvine KD, (2013) Regulation of Hippo signaling by EGFR-MAPK signaling through Ajuba family proteins. Dev Cell 24: 459-471
    • (2013) Dev Cell , vol.24 , pp. 459-471
    • Reddy, B.V.1    Irvine, K.D.2
  • 42
    • 77950478873 scopus 로고    scopus 로고
    • Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded
    • Robinson BS, Huang J, Hong Y, Moberg KH, (2010) Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded. Curr Biol 20: 582-590
    • (2010) Curr Biol , vol.20 , pp. 582-590
    • Robinson, B.S.1    Huang, J.2    Hong, Y.3    Moberg, K.H.4
  • 43
    • 33644959986 scopus 로고    scopus 로고
    • AlphaPIX and betaPIX and their role in focal adhesion formation
    • Rosenberger G, Kutsche K, (2006) AlphaPIX and betaPIX and their role in focal adhesion formation. Eur J Cell Biol 85: 265-274
    • (2006) Eur J Cell Biol , vol.85 , pp. 265-274
    • Rosenberger, G.1    Kutsche, K.2
  • 45
    • 59149097659 scopus 로고    scopus 로고
    • Structures of dimeric GIT1 and trimeric beta-PIX and implications for GIT-PIX complex assembly
    • Schlenker O, Rittinger K, (2009) Structures of dimeric GIT1 and trimeric beta-PIX and implications for GIT-PIX complex assembly. J Mol Biol 386: 280-289
    • (2009) J Mol Biol , vol.386 , pp. 280-289
    • Schlenker, O.1    Rittinger, K.2
  • 46
    • 84866621806 scopus 로고    scopus 로고
    • Regulation of the Hippo pathway by cell architecture and mechanical signals
    • Schroeder MC, Halder G, (2012) Regulation of the Hippo pathway by cell architecture and mechanical signals. Semin Cell Dev Biol 23: 803-811
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 803-811
    • Schroeder, M.C.1    Halder, G.2
  • 47
    • 84890916735 scopus 로고    scopus 로고
    • Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
    • Serrano I, McDonald PC, Lock F, Muller WJ, Dedhar S, (2013) Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun 4: 2976
    • (2013) Nat Commun , vol.4 , pp. 2976
    • Serrano, I.1    McDonald, P.C.2    Lock, F.3    Muller, W.J.4    Dedhar, S.5
  • 48
    • 70349338886 scopus 로고    scopus 로고
    • The skinny on Fat: An enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity
    • Sopko R, McNeill H, (2009) The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity. Curr Opin Cell Biol 21: 717-723
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 717-723
    • Sopko, R.1    McNeill, H.2
  • 54
    • 80051923057 scopus 로고    scopus 로고
    • Hippo pathway regulation by cell morphology and stress fibers
    • Wada K, Itoga K, Okano T, Yonemura S, Sasaki H, (2011) Hippo pathway regulation by cell morphology and stress fibers. Development 138: 3907-3914
    • (2011) Development , vol.138 , pp. 3907-3914
    • Wada, K.1    Itoga, K.2    Okano, T.3    Yonemura, S.4    Sasaki, H.5
  • 56
    • 84874257648 scopus 로고    scopus 로고
    • The Hippo pathway: Regulators and regulations
    • Yu FX, Guan KL, (2013) The Hippo pathway: regulators and regulations. Genes Dev 27: 355-371
    • (2013) Genes Dev , vol.27 , pp. 355-371
    • Yu, F.X.1    Guan, K.L.2
  • 60
    • 78650895035 scopus 로고    scopus 로고
    • Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
    • Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei Q, Guan KL, (2011) Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev 25: 51-63
    • (2011) Genes Dev , vol.25 , pp. 51-63
    • Zhao, B.1    Li, L.2    Lu, Q.3    Wang, L.H.4    Liu, C.Y.5    Lei, Q.6    Guan, K.L.7
  • 61
    • 84855326431 scopus 로고    scopus 로고
    • Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
    • Zhao B, Li L, Wang L, Wang CY, Yu J, Guan KL, (2012) Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev 26: 54-68
    • (2012) Genes Dev , vol.26 , pp. 54-68
    • Zhao, B.1    Li, L.2    Wang, L.3    Wang, C.Y.4    Yu, J.5    Guan, K.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.