-
1
-
-
62449089909
-
The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
-
Doi, T., Kato, L., Ito, S. et al. 2009. The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination. Proc. Natl Acad. Sci. USA 106:2758.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 2758
-
-
Doi, T.1
Kato, L.2
Ito, S.3
-
2
-
-
3242795967
-
Separate domains of AID are required for somatic hypermutation and class-switch recombination
-
Shinkura, R., Ito, S., Begum, N. A. et al. 2004. Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nat. Immunol. 5:707.
-
(2004)
Nat. Immunol
, vol.5
, pp. 707
-
-
Shinkura, R.1
Ito, S.2
Begum, N. A.3
-
3
-
-
0141992113
-
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
-
Barreto, V., Reina-San-Martin, B., Ramiro, A. R., McBride, K. M. and Nussenzweig, M. C. 2003. C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol. Cell 12:501.
-
(2003)
Mol. Cell
, vol.12
, pp. 501
-
-
Barreto, V.1
Reina-San-Martin, B.2
Ramiro, A. R.3
McBride, K. M.4
Nussenzweig, M. C.5
-
4
-
-
0041381361
-
AID mutant analyses indicate requirement for class-switch-specific cofactors
-
Ta, V. T., Nagaoka, H., Catalan, N. et al. 2003. AID mutant analyses indicate requirement for class-switch-specific cofactors. Nat. Immunol. 4:843.
-
(2003)
Nat. Immunol
, vol.4
, pp. 843
-
-
Ta, V. T.1
Nagaoka, H.2
Catalan, N.3
-
5
-
-
34249807921
-
DNA deamination in immunity: AID in the context of its APOBEC relatives
-
Conticello, S. G., Langlois, M. A., Yang, Z. and Neuberger, M. S. 2007. DNA deamination in immunity: AID in the context of its APOBEC relatives. Adv. Immunol. 94:37.
-
(2007)
Adv. Immunol
, vol.94
, pp. 37
-
-
Conticello, S. G.1
Langlois, M. A.2
Yang, Z.3
Neuberger, M. S.4
-
6
-
-
34249801641
-
Discovery of activation-induced cytidine deaminase, the engraver of antibody memory
-
Muramatsu, M., Nagaoka, H., Shinkura, R., Begum, N. A. and Honjo, T. 2007. Discovery of activation-induced cytidine deaminase, the engraver of antibody memory. Adv. Immunol. 94:1.
-
(2007)
Adv. Immunol
, vol.94
, pp. 1
-
-
Muramatsu, M.1
Nagaoka, H.2
Shinkura, R.3
Begum, N. A.4
Honjo, T.5
-
7
-
-
0037108463
-
Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice
-
Rada, C., Williams, G. T., Nilsen, H., Barnes, D. E., Lindahl, T. and Neuberger, M. S. 2002. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice. Curr. Biol. 12:1748.
-
(2002)
Curr. Biol
, vol.12
, pp. 1748
-
-
Rada, C.1
Williams, G. T.2
Nilsen, H.3
Barnes, D. E.4
Lindahl, T.5
Neuberger, M. S.6
-
8
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt, S. K., Harris, R. S. and Neuberger, M. S. 2002. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418:99.
-
(2002)
Nature
, vol.418
, pp. 99
-
-
Petersen-Mahrt, S. K.1
Harris, R. S.2
Neuberger, M. S.3
-
9
-
-
3142765336
-
Class-switch recombination: interplay of transcription, DNA deamination and DNA repair
-
Chaudhuri, J. and Alt, F. W. 2004. Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat. Rev. Immunol. 4:541.
-
(2004)
Nat. Rev. Immunol
, vol.4
, pp. 541
-
-
Chaudhuri, J.1
Alt, F. W.2
-
10
-
-
78650307766
-
Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions
-
Maul, R. W., Saribasak, H., Martomo, S. A. et al. 2011. Uracil residues dependent on the deaminase AID in immunoglobulin gene variable and switch regions. Nat. Immunol. 12:70.
-
(2011)
Nat. Immunol
, vol.12
, pp. 70
-
-
Maul, R. W.1
Saribasak, H.2
Martomo, S. A.3
-
11
-
-
6344256944
-
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
-
Rada, C., Di Noia, J. M. and Neuberger, M. S. 2004. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell 16:163.
-
(2004)
Mol. Cell
, vol.16
, pp. 163
-
-
Rada, C.1
Di Noia, J. M.2
Neuberger, M. S.3
-
12
-
-
84879124762
-
Separation of function between isotype switching and affinity maturation in vivo during acute immune responses and circulating autoantibodies in UNG-deficient mice
-
Zahn, A., Daugan, M., Safavi, S. et al. 2013. Separation of function between isotype switching and affinity maturation in vivo during acute immune responses and circulating autoantibodies in UNG-deficient mice. J. Immunol. 190:5949.
-
(2013)
J. Immunol
, vol.190
, pp. 5949
-
-
Zahn, A.1
Daugan, M.2
Safavi, S.3
-
13
-
-
0035003254
-
DNA breaks in hypermutating immunoglobulin genes: evidence for a break-and-repair pathway of somatic hypermutation
-
Kong, Q. and Maizels, N. 2001. DNA breaks in hypermutating immunoglobulin genes: evidence for a break-and-repair pathway of somatic hypermutation. Genetics 158:369.
-
(2001)
Genetics
, vol.158
, pp. 369
-
-
Kong, Q.1
Maizels, N.2
-
14
-
-
33846424933
-
Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation
-
Ronai, D., Iglesias-Ussel, M. D., Fan, M., Li, Z., Martin, A. and Scharff, M. D. 2007. Detection of chromatin-associated single-stranded DNA in regions targeted for somatic hypermutation. J. Exp. Med. 204:181.
-
(2007)
J. Exp. Med
, vol.204
, pp. 181
-
-
Ronai, D.1
Iglesias-Ussel, M. D.2
Fan, M.3
Li, Z.4
Martin, A.5
Scharff, M. D.6
-
15
-
-
84864309038
-
DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions
-
Saribasak, H., Maul, R. W., Cao, Z. et al. 2012. DNA polymerase ζ generates tandem mutations in immunoglobulin variable regions. J. Exp. Med. 209:1075.
-
(2012)
J. Exp. Med
, vol.209
, pp. 1075
-
-
Saribasak, H.1
Maul, R. W.2
Cao, Z.3
-
16
-
-
84862108532
-
Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity
-
Daly, J., Bebenek, K., Watt, D. L. et al. 2012. Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity. J. Immunol. 188:5528.
-
(2012)
J. Immunol
, vol.188
, pp. 5528
-
-
Daly, J.1
Bebenek, K.2
Watt, D. L.3
-
17
-
-
84896504436
-
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
-
Yousif, A. S., Stanlie, A., Mondal, S., Honjo, T. and Begum, N. A. 2014. Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase. Proc. Natl Acad. Sci. USA 111:E1016.
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. E1016
-
-
Yousif, A. S.1
Stanlie, A.2
Mondal, S.3
Honjo, T.4
Begum, N. A.5
-
18
-
-
29144433943
-
Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA
-
Auerbach, P., Bennett, R. A., Bailey, E. A., Krokan, H. E. and Demple, B. 2005. Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA. Proc. Natl Acad. Sci. USA 102:17711.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 17711
-
-
Auerbach, P.1
Bennett, R. A.2
Bailey, E. A.3
Krokan, H. E.4
Demple, B.5
-
19
-
-
68149178379
-
A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation
-
Masuda, K., Ouchida, R., Li, Y., Gao, X., Mori, H. and Wang, J. Y. 2009. A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation. J. Immunol. 183:1846.
-
(2009)
J. Immunol
, vol.183
, pp. 1846
-
-
Masuda, K.1
Ouchida, R.2
Li, Y.3
Gao, X.4
Mori, H.5
Wang, J. Y.6
-
20
-
-
0029065847
-
Specificities of the Saccharomyces cerevisiae rad6, rad18, and rad52 mutators exhibit different degrees of dependence on the REV3 gene product, a putative nonessential DNA polymerase
-
Roche, H., Gietz, R. D. and Kunz, B. A. 1995. Specificities of the Saccharomyces cerevisiae rad6, rad18, and rad52 mutators exhibit different degrees of dependence on the REV3 gene product, a putative nonessential DNA polymerase. Genetics 140:443.
-
(1995)
Genetics
, vol.140
, pp. 443
-
-
Roche, H.1
Gietz, R. D.2
Kunz, B. A.3
-
21
-
-
33845657443
-
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
-
Wang, M., Wu, W., Wu, W. et al. 2006. PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways. Nucleic Acids Res. 34:6170.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 6170
-
-
Wang, M.1
Wu, W.2
Wu, W.3
-
22
-
-
84903760115
-
Chromatin reader brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining
-
Stanlie, A., Yousif, A. S., Akiyama, H., Honjo, T. and Begum, N. A. 2014. Chromatin reader brd4 functions in Ig class switching as a repair complex adaptor of nonhomologous end-joining. Mol. Cell 55:97.
-
(2014)
Mol. Cell
, vol.55
, pp. 97
-
-
Stanlie, A.1
Yousif, A. S.2
Akiyama, H.3
Honjo, T.4
Begum, N. A.5
-
23
-
-
62449164136
-
Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination
-
Begum, N. A., Stanlie, A., Doi, T. et al. 2009. Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination. Proc. Natl Acad. Sci. USA 106:2752.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 2752
-
-
Begum, N. A.1
Stanlie, A.2
Doi, T.3
-
24
-
-
49649100703
-
Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants
-
Larsen, E., Kleppa, L., Meza, T. J. et al. 2008. Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants. Cancer Res. 68:4571.
-
(2008)
Cancer Res
, vol.68
, pp. 4571
-
-
Larsen, E.1
Kleppa, L.2
Meza, T. J.3
-
25
-
-
34447132813
-
Fen1 mutations result in autoimmunity, chronic inflammation and cancers
-
Zheng, L., Dai, H., Zhou, M. et al. 2007. Fen1 mutations result in autoimmunity, chronic inflammation and cancers. Nat. Med. 13:812.
-
(2007)
Nat. Med
, vol.13
, pp. 812
-
-
Zheng, L.1
Dai, H.2
Zhou, M.3
-
26
-
-
0037213268
-
Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells
-
De Silva, F. S. and Moss, B. 2003. Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells. J. Virol. 77:159.
-
(2003)
J. Virol
, vol.77
, pp. 159
-
-
De Silva, F. S.1
Moss, B.2
-
27
-
-
33645639121
-
Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase
-
Stanitsa, E. S., Arps, L. and Traktman, P. 2006. Vaccinia virus uracil DNA glycosylase interacts with the A20 protein to form a heterodimeric processivity factor for the viral DNA polymerase. J. Biol. Chem. 281:3439.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 3439
-
-
Stanitsa, E. S.1
Arps, L.2
Traktman, P.3
-
28
-
-
79952288614
-
Uracil DNA N-glycosylase promotes assembly of human centromere protein A
-
Zeitlin, S. G., Chapados, B. R., Baker, N. M., Tai, C., Slupphaug, G. and Wang, J. Y. 2011. Uracil DNA N-glycosylase promotes assembly of human centromere protein A. PLoS One 6:e17151.
-
(2011)
PLoS One
, vol.6
, pp. e17151
-
-
Zeitlin, S. G.1
Chapados, B. R.2
Baker, N. M.3
Tai, C.4
Slupphaug, G.5
Wang, J. Y.6
-
29
-
-
33846951485
-
Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination
-
Begum, N. A., Izumi, N., Nishikori, M., Nagaoka, H., Shinkura, R. and Honjo, T. 2007. Requirement of non-canonical activity of uracil DNA glycosylase for class switch recombination. J. Biol. Chem. 282:731.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 731
-
-
Begum, N. A.1
Izumi, N.2
Nishikori, M.3
Nagaoka, H.4
Shinkura, R.5
Honjo, T.6
-
30
-
-
84870427871
-
Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination
-
Zan, H., White, C. A., Thomas, L. M. et al. 2012. Rev1 recruits ung to switch regions and enhances du glycosylation for immunoglobulin class switch DNA recombination. Cell Rep. 2:1220.
-
(2012)
Cell Rep
, vol.2
, pp. 1220
-
-
Zan, H.1
White, C. A.2
Thomas, L. M.3
-
31
-
-
39149099085
-
Two levels of protection for the B cell genome during somatic hypermutation
-
Liu, M., Duke, J. L., Richter, D. J. et al. 2008. Two levels of protection for the B cell genome during somatic hypermutation. Nature 451:841.
-
(2008)
Nature
, vol.451
, pp. 841
-
-
Liu, M.1
Duke, J. L.2
Richter, D. J.3
-
32
-
-
0028934537
-
Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis
-
Mol, C. D., Arvai, A. S., Slupphaug, G. et al. 1995. Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis. Cell 80:869.
-
(1995)
Cell
, vol.80
, pp. 869
-
-
Mol, C. D.1
Arvai, A. S.2
Slupphaug, G.3
-
33
-
-
34547629029
-
Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly
-
Schormann, N., Grigorian, A., Samal, A., Krishnan, R., DeLucas, L., and Chattopadhyay, D. 2007. Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly. BMC Struct. Biol. 7:45.
-
(2007)
BMC Struct. Biol
, vol.7
, pp. 45
-
-
Schormann, N.1
Grigorian, A.2
Samal, A.3
Krishnan, R.4
DeLucas, L.5
Chattopadhyay, D.6
|