메뉴 건너뛰기




Volumn 106, Issue 8, 2009, Pages 2758-2763

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavaqe in class switch recombination

Author keywords

C terminal deletion mutant; Chromosomal translocation synapse formation; Target specificity

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; ESTROGEN RECEPTOR; IMMUNOGLOBULIN A; TAMOXIFEN;

EID: 62449089909     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0813253106     Document Type: Article
Times cited : (53)

References (29)
  • 1
    • 0035404678 scopus 로고    scopus 로고
    • Linking class-switch recombination with somatic hyper- mutation
    • Kinoshita K, Honjo T (2001) Linking class-switch recombination with somatic hyper- mutation. Nat Rev Mol Cell Biol 2:493-503.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 493-503
    • Kinoshita, K.1    Honjo, T.2
  • 2
    • 0036212917 scopus 로고    scopus 로고
    • Molecular mechanism of class switch recombination: Linkage with somatic hypermutation
    • Honjo T, Kinoshita K, Muramatsu M (2002) Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol 20:165-196.
    • (2002) Annu Rev Immunol , vol.20 , pp. 165-196
    • Honjo, T.1    Kinoshita, K.2    Muramatsu, M.3
  • 3
    • 0035818990 scopus 로고    scopus 로고
    • AID is required to initiate Nbs1/gamrna-H2AX focus formation and mutations at sites of class switching
    • Petersen S, et al. (2001) AID is required to initiate Nbs1/gamrna-H2AX focus formation and mutations at sites of class switching. Nature 414:660-665.
    • (2001) Nature , vol.414 , pp. 660-665
    • Petersen, S.1
  • 4
    • 13844315325 scopus 로고    scopus 로고
    • Nagaoka H, Ito S, Muramatsu M, Nakata M, Honjo T (2005) DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase. Proc Natl Acad 5ci USA 102:2022-2027.
    • Nagaoka H, Ito S, Muramatsu M, Nakata M, Honjo T (2005) DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase. Proc Natl Acad 5ci USA 102:2022-2027.
  • 5
    • 0034268780 scopus 로고    scopus 로고
    • Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA-editing enzyme
    • Muramatsu M, et al. (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA-editing enzyme. Cell 102:553-563.
    • (2000) Cell , vol.102 , pp. 553-563
    • Muramatsu, M.1
  • 6
    • 0037019315 scopus 로고    scopus 로고
    • AID mutates E. coli, suggesting a DNA deamination mechanism for antibody diversification
    • Petersen-Mahrt SK, Harris RS, Neuberger MS (2002) AID mutates E. coli, suggesting a DNA deamination mechanism for antibody diversification. Nature 418:99-103.
    • (2002) Nature , vol.418 , pp. 99-103
    • Petersen-Mahrt, S.K.1    Harris, R.S.2    Neuberger, M.S.3
  • 7
    • 0041381361 scopus 로고    scopus 로고
    • AID mutant analyses indicate requirement for class-switch-specific cofactors
    • Ta VT, et al. (2003) AID mutant analyses indicate requirement for class-switch-specific cofactors. Nat Immunol 4:843-848.
    • (2003) Nat Immunol , vol.4 , pp. 843-848
    • Ta, V.T.1
  • 8
    • 0141992113 scopus 로고    scopus 로고
    • C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
    • Barreto V, Reina-San-Martin B, Ramiro AR, McBride KM, Nussenzweig MC (2003) C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol Cell 12:501-508.
    • (2003) Mol Cell , vol.12 , pp. 501-508
    • Barreto, V.1    Reina-San-Martin, B.2    Ramiro, A.R.3    McBride, K.M.4    Nussenzweig, M.C.5
  • 9
    • 3242795967 scopus 로고    scopus 로고
    • Separate domains of AID are required for somatic hypermutation and class-switch recombination
    • Shinkura R, et al. (2004) Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nat Immunol 5:707-712.
    • (2004) Nat Immunol , vol.5 , pp. 707-712
    • Shinkura, R.1
  • 10
    • 4344560868 scopus 로고    scopus 로고
    • Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch
    • Begum NA, et al. (2004) Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch. Science 305:1160-1163.
    • (2004) Science , vol.305 , pp. 1160-1163
    • Begum, N.A.1
  • 11
    • 4644257681 scopus 로고    scopus 로고
    • Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break
    • Shroff R, et al. (2004) Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol 14:1703-1711.
    • (2004) Curr Biol , vol.14 , pp. 1703-1711
    • Shroff, R.1
  • 12
    • 33745255099 scopus 로고    scopus 로고
    • A topoisomerase llbeta-mediated dsDNA break required for regulated transcription
    • Ju BG, et al. (2006) A topoisomerase llbeta-mediated dsDNA break required for regulated transcription. Science 312:1798-1802.
    • (2006) Science , vol.312 , pp. 1798-1802
    • Ju, B.G.1
  • 13
    • 1242341972 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm-like apolipoprotein B mRNA-editing catalytic polypeptide 1
    • Ito S, et al. (2004) Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm-like apolipoprotein B mRNA-editing catalytic polypeptide 1. Proc Natl Acad Sci USA 101:1975-1980.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1975-1980
    • Ito, S.1
  • 14
    • 2442474264 scopus 로고    scopus 로고
    • Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase
    • McBride KM, Barreto V, Ramiro AR, Stavropoulos P, Nussenzweig MC (2004) Somatic hypermutation is limited by CRM1-dependent nuclear export of activation-induced deaminase. J Exp Med 199:1235-1244.
    • (2004) J Exp Med , vol.199 , pp. 1235-1244
    • McBride, K.M.1    Barreto, V.2    Ramiro, A.R.3    Stavropoulos, P.4    Nussenzweig, M.C.5
  • 15
    • 62449207876 scopus 로고    scopus 로고
    • Requirement of the carboxy-terminal domain of AID for its mRNA complex formation in vivo
    • in press
    • Nonaka T, et al. (2009) Requirement of the carboxy-terminal domain of AID for its mRNA complex formation in vivo. Proc Natl Acad Sci U S A, in press.
    • (2009) Proc Natl Acad Sci U S A
    • Nonaka, T.1
  • 16
    • 0037418279 scopus 로고    scopus 로고
    • De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
    • HonjoT
    • Doi T, Kinoshita K, Ikegawa M, Muramatsu M, HonjoT (2003) De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination. Proc Natl Acad Sci USA 100:2634-2638.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2634-2638
    • Doi, T.1    Kinoshita, K.2    Ikegawa, M.3    Muramatsu, M.4
  • 17
    • 0037076967 scopus 로고    scopus 로고
    • AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts
    • Yoshikawa K, et al. (2002) AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science 296:2033-2036.
    • (2002) Science , vol.296 , pp. 2033-2036
    • Yoshikawa, K.1
  • 18
    • 57349135239 scopus 로고    scopus 로고
    • Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
    • ShivarovV, Shinkura R, Honjo T(2008) Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants. Proc Natl Acad Sci USA 105:15866-15871.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 15866-15871
    • Shivarov, V.1    Shinkura, R.2    Honjo, T.3
  • 19
    • 0029092910 scopus 로고
    • Determination of radiation-induced DNA strand breaks in individual cells by non-radioactive labelling of 3' OH ends. int
    • Kodym R, Horth E (1995) Determination of radiation-induced DNA strand breaks in individual cells by non-radioactive labelling of 3' OH ends. int J Radiat Biol 68:133-139.
    • (1995) J Radiat Biol , vol.68 , pp. 133-139
    • Kodym, R.1    Horth, E.2
  • 20
    • 0242331621 scopus 로고    scopus 로고
    • RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
    • Eto T, Kinoshita K, Yoshikawa K, Muramatsu M, Honjo T (2003) RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells. Proc Natl Acad Sci USA 100:12895-12898.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12895-12898
    • Eto, T.1    Kinoshita, K.2    Yoshikawa, K.3    Muramatsu, M.4    Honjo, T.5
  • 21
    • 4644257592 scopus 로고    scopus 로고
    • AID is required for c-myc/IgH chromosome translocations in vivo
    • Ramiro AR, et al. (2004) AID is required for c-myc/IgH chromosome translocations in vivo. Cell 118:431-438.
    • (2004) Cell , vol.118 , pp. 431-438
    • Ramiro, A.R.1
  • 22
    • 33846804438 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice
    • Kotani A, et al. (2007) Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice. Proc Natl Acad Sci U S A 104:1616- 1620.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 1616-1620
    • Kotani, A.1
  • 23
    • 39149099085 scopus 로고    scopus 로고
    • Two levels of protection for the B cell genome during somatic hypermutation
    • Liu M, et al. (2008) Two levels of protection for the B cell genome during somatic hypermutation. Nature 451:841-845.
    • (2008) Nature , vol.451 , pp. 841-845
    • Liu, M.1
  • 25
    • 0035067615 scopus 로고    scopus 로고
    • Palindromic but not G-rich sequences are targets of class switch recombination, int
    • Tashiro J, Kinoshita K, Honjo T (2001) Palindromic but not G-rich sequences are targets of class switch recombination, int Immunol 13:495-505.
    • (2001) Immunol , vol.13 , pp. 495-505
    • Tashiro, J.1    Kinoshita, K.2    Honjo, T.3
  • 26
    • 0023187644 scopus 로고
    • Mitogen-driven B cell proliferation and differentiation are not accompanied by hypermutation of immunoglobulin variable region genes
    • Manser T (1987) Mitogen-driven B cell proliferation and differentiation are not accompanied by hypermutation of immunoglobulin variable region genes. J Immunol 139:234-238.
    • (1987) J Immunol , vol.139 , pp. 234-238
    • Manser, T.1
  • 27
    • 42649123314 scopus 로고    scopus 로고
    • Mechanism and regulation of class switch recombination
    • Stavnezer J, Guikema JE, Schrader CE (2008) Mechanism and regulation of class switch recombination. Annu Rev Immunol 26:261-292.
    • (2008) Annu Rev Immunol , vol.26 , pp. 261-292
    • Stavnezer, J.1    Guikema, J.E.2    Schrader, C.E.3
  • 28
    • 36148940618 scopus 로고    scopus 로고
    • S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase
    • Wuerffel R, et al. (2007) S-S synapsis during class switch recombination is promoted by distantly located transcriptional elements and activation-induced deaminase. Immunity 27:711 -722.
    • (2007) Immunity , vol.27 , pp. 711-722
    • Wuerffel, R.1
  • 29
    • 33846606769 scopus 로고    scopus 로고
    • Antibody class switching mediated by yeast endonuclease- generated DNA breaks
    • Zarrin AA, et al. (2007) Antibody class switching mediated by yeast endonuclease- generated DNA breaks. Science 315:377-381.
    • (2007) Science , vol.315 , pp. 377-381
    • Zarrin, A.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.