17A-Estradiol protects against glucosamine-induced pancreatic A-cell dysfunction

Menopause

Volumn 21, Issue 11, 2014, Pages 1239-1248

  Kang, Lin ^a,b   Chen, Chung Hwan ^c,d,e,f,g   Wu, Meng Hsing ^b   Chang, Je Ken ^c,d,e,g   Chang, Fong Ming ^a,b   Cheng, Juei Tang ^a,h  

^a Da An Women and Children Hospital   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^c Department of Orthopedics ^*  (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

^g KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^h CHI MEI MEDICAL CENTER   (Taiwan)

Author keywords

17a estradiol y calcium influx y endoplasmic reticulum stress y glucosamine y pancreatic a cell dysfunction

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CCAAT ENHANCER BINDING PROTEIN; ENDOPLASMIC RETICULUM STRESS RELATED PROTEIN; ESTRADIOL; GLUCOSAMINE; INITIATION FACTOR 2ALPHA; INSULIN; PHOSPHO C JUN N TERMINAL KINASE; PHOSPHOEUKARYOTIC INITIATION FACTOR 2 ALPHA; PHOSPHOPROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; PHOSPHOTRANSFERASE; POTASSIUM; PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ANTIESTROGEN; CALCIUM; FULVESTRANT; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATTENUATION; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; FEMALE; GLUCOSAMINE INDUCED PANCREATIC BETA CELL DYSFUNCTION; INSULIN RELEASE; INSULIN RESISTANCE; MIN6 CELL LINE; NONHUMAN; OVARIECTOMY; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET DISEASE; POLYMERASE CHAIN REACTION; RAT; SHAM PROCEDURE; STAINING; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; GENE EXPRESSION; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; SECRETION (PROCESS); SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CALCIUM; CELL LINE; ENDOPLASMIC RETICULUM; ESTRADIOL; ESTROGEN ANTAGONISTS; FEMALE; GENE EXPRESSION; GLUCOSAMINE; INSULIN; INSULIN-SECRETING CELLS; MICE; OVARIECTOMY; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 84918539708     PISSN: 10723714     EISSN: 15300374     Source Type: Journal    
DOI: 10.1097/gme.0000000000000232     Document Type: Article

References (61)

1. Hanna FS, Teichtahl AJ, Wluka AE, et al. Women have increased rates of cartilage loss and progression of cartilage defects at the knee than men: A gender study of adults without clinical knee osteoarthritis. Menopause 2009;16:666-670.
2. Kennedy J. Herb and supplement use in the US adult population. Clin Ther 2005;27:1847-1858.
3. Ciaraldi TP, Carter L, Nikoulina S, Mudaliar S, McClain DA, Henry RR. Glucosamine regulation of glucose metabolism in cultured human skeletal muscle cells: divergent effects on glucose transport/phosphorylation and glycogen synthase in non-diabetic and type 2 diabetic subjects. Endocrinology 1999;140:3971-3980.
4. Pru JK. The combined effects of menopause and dietary glucosamine on the development of insulin resistance. Menopause 2012;19:487-488.
5. D'Alessandris C, Andreozzi F, Federici M, et al. Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic A-cells. FASEB J 2004; 18:959-961.
6. Biggee BA, Blinn CM, Nuite M, Silbert JE, McAlindon TE. Effects of oral glucosamine sulphate on serum glucose and insulin during an oral glucose tolerance test of subjects with osteoarthritis. Ann Rheum Dis 2007;66:260-262.
7. Monauni T, Zenti MG, Cretti A, et al. Effects of glucosamine infusion on insulin secretion and insulin action in humans. Diabetes 2000;49: 926-935.
8. Muniyappa R, Karne RJ, Hall G, et al. Oral glucosamine for 6 weeks at standard doses does not cause or worsen insulin resistance or endothelial dysfunction in lean or obese subjects. Diabetes 2006;55:3142-3150.
9. Scroggie DA, Albright A, Harris MD. The effect of glucosamine-chondroitin supplementation on glycosylated hemoglobin levels in patients with type 2 diabetes mellitus: A placebo-controlled, double-blinded, randomized clinical trial. Arch Intern Med 2003;163:1587-1590.
10. Balkan B, Dunning BE. Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats. Diabetes 1994;43:1173-1179.
11. Shankar RR, Zhu JS, Baron AD. Glucosamine infusion in rats mimics the A-cell dysfunction of non insulin-dependent diabetes mellitus. Metabolism 1998;47:573-577.
12. Kim YK, Park JH, Park SH, et al. Protective role of glucagon-like peptide-1 against glucosamine-induced cytotoxicity in pancreatic A cells. Cell Physiol Biochem 2010;25:211-220.
13. Lafontaine-Lacasse M, Dore G, Picard F. Hexosamines stimulate apoptosis by altering SIRT1 action and levels in rodent pancreatic A-cells. J Endocrinol 2011;208:41-49.
14. Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev 2013;34:309-338.
15. LeMay C, Chu K, Hu M, et al. Estrogens protect pancreatic A-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice. Proc Natl Acad Sci U S A 2006;103:9232-9237.
16. Riant E, Waget A, Cogo H, Arnal JF, Burcelin R, Gourdy P. Estrogens protect against high-fat dietYinduced insulin resistance and glucose intolerance in mice. Endocrinology 2009;150:2109-2117.
17. Tiano JP, Delghingaro-Augusto V, Le May C, et al. Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents A cell failure in rodent models of type 2 diabetes. J Clin Invest 2011;121:3331-3342.
18. Liu S, Le May C, Wong WP, et al. Importance of extranuclear estrogen receptor-> and membrane G proteinYcoupled estrogen receptor in pancreatic islet survival. Diabetes 2009;58:2292-2302.
19. Liu S, Mauvais-Jarvis F. Minire view: Estrogenic protection of A-cell failure in metabolic diseases. Endocrinology 2010;151:859-864.
20. Bernales S, Papa FR, Walter P. Intracellular signaling by the unfolded protein response. Annu Rev Cell Dev Biol 2006;22:487-508.
21. Marchetti P, Bugliani M, Lupi R, et al. The endoplasmic reticulum in pancreatic A cells of type 2 diabetes patients. Diabetologia 2007;50: 2486-2494.
22. Laybutt DR, Preston AM, Akerfeldt MC, et al. Endoplasmic reticulum stress contributes to A cell apoptosis in type 2 diabetes. Diabetologia 2007;50:752-763.
23. Hwang MS, Baek WK. Glucosamine induces autophagic cell death through the stimulation of ER stress in human glioma cancer cells. Biochem Biophys Res Commun 2010;399:111-116.
24. Morin MJ, Porter CW, McKernan P, Bernacki RJ. The biochemical and ultra structural effects of tunicamycin and D-glucosamine in L1210 leukemic cells. J Cell Physiol 1983;114:162-172.
25. Kang L, Chen CH, Cheng YC, et al. Glucosamine-induced insulin resistance in ovariectomized rats is relevant to decreasing the expression of glucose transport protein subtype 4 in the skeletal muscle and in increasing the size of pancreatic islets. Menopause 2012;19:496-502.
26. Chen CH, Kang L, Lin RW, et al. (j)-Epigallocatechin-3-gallate improves bone microarchitecture in ovariectomized rats. Menopause 2013;20: 687-694.
27. Ho ML, Chen YH, Liao HJ, et al. Simvastatin increases osteoblasts and osteogenic proteins in ovariectomized rats. Eur J Clin Invest 2009;39: 296-303.
28. Juan YS, Chuang SM, Long CY, et al. Neuroprotection of green tea catechins on surgical menopause-induced overactive bladder in a rat model. Menopause 2012;19:346-354.
29. Rachon D, Vortherms T, Seidlova-Wuttke D, Wuttke W. Effects of dietary equol on body weight gain, intra-abdominal fat accumulation, plasma lipids, and glucose tolerance in ovariectomized Sprague-Dawley rats. Menopause 2007;14:925-932.
30. Galipeau D, Verma S, McNeill JH. Female rats are protected against fructose-induced changes in metabolism and blood pressure. Am J Physiol Heart Circ Physiol 2002;283:H2478-H2484.
31. Liu ML, Xu X, Rang WQ, Li YJ, Song HP. Influence of ovariectomy and 17A-estradiol treatment on insulin sensitivity, lipid metabolism and post ischemic cardiac function. Int J Cardiol 2004;97:485-493.
32. Chen CH, Ho ML, Chang JK, Hung SH, Wang GJ. Green tea catechin enhances osteogenesis in a bone marrow mesenchymal stem cell line. Osteoporos Int 2005;16:2039-2045.
33. Butler AE, Cao-Minh L, Galasso R, et al. Adaptive changes in pancreatic A cell fractional area and A cell turnover in human pregnancy. Diabetologia 2010;53:2167-2176.
34. Salom JB, Burguete MC, Perez-Asensio FJ, Torregrosa G, Alborch E. Relaxant effects of 17-A-estradiol in cerebral arteries through Ca(2+) entry inhibition. J Cereb Blood Flow Metab 2001;21:422-429.
35. Chen WC, Cheng JS, Chou KJ, et al. Effect of 17A-estradiol on intracellular Ca(2+) levels in renal tubular cells. Pharmacology 2002;64: 84-90.
36. Chen CH, Lin YS, Fu YC, et al. Electromagnetic fields enhance chondrogenesis of human adipose-derived stem cells in a chondrogenic microenvironment in vitro. J Appl Physiol 2013;114:647-655.
37. Anello M, Spampinato D, Piro S, Purrello F, Rabuazzo AM. Glucosamine- induced alterations of mitochondrial function in pancreatic A-cells: possible role of protein glycosylation. Am J Physiol Endocrinol Metab 2004;287:E602-E608.
38. Yoshikawa H, Tajiri Y, Sako Y, Hashimato T, Umeda F, Nawata H. Glucosamine-induced A-cell dysfunction: A possible involvement of glucokinase or glucose-transporter type 2. Pancreas 2002;24:228-234.
39. Ashcroft FM, Harrison DE, Ashcroft SJ. Glucose induces closure of single potassium channels in isolated rat pancreatic A-cells. Nature 1984; 312:446-448.
40. Rorsman P, Renstrom E. Insulin granule dynamics in pancreatic A cells. Diabetologia 2003;46:1029-1045.
41. Shyng S, Nichols CG. Octameric stoichiometry of the KATP channel complex. J Gen Physiol 1997;110:655-664.
42. Wollheim CB, Sharp GW. Regulation of insulin release by calcium. Physiol Rev 1981;61:914-973.
43. Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. A-Cell deficit and increased A-cell apoptosis in humans with type 2 diabetes. Diabetes 2003;52:102-110.
44. Eizirik DL, Cardozo AK, Cnop M. The role for endoplasmic reticulum stress in diabetes mellitus. Endocr Rev 2008;29:42-61.
45. Scheuner D, Vander Mierde D, Song B, et al. Control of mRNA translation preserves endoplasmic reticulum function in A cells and maintains glucose homeostasis. Nat Med 2005;11:757-764.
46. Back SH, Scheuner D, Han J, et al. Translation attenuation through eIF2 phosphorylation prevents oxidative stress and maintains the differentiated state in A cells. Cell Metab 2009;10:13-26.
47. Cnop M, Ladriere L, Hekerman P, et al. Selective inhibition of eukaryotic translation initiation factor 2> dephosphorylation potentiates fatty acid Yinduced endoplasmic reticulum stress and causes pancreatic A-cell dysfunction and apoptosis. J Biol Chem 2007;282:3989-3997.
48. Manson JE, Rimm EB, Colditz GA, et al. A prospective study of postmenopausal estrogen therapy and subsequent incidence of nonYinsulin-dependent diabetes mellitus. Ann Epidemiol 1992;2:665-673.
49. Margolis KL, Bonds DE, Rodabough RJ, et al. Effect of oestrogen plus progestin on the incidence of diabetes in postmenopausal women: results from the Women's Health Initiative Hormone Trial. Diabetologia 2004; 47:1175-1187.
50. Kanaya AM, Herrington D, Vittinghoff E, et al. Glycemic effects of postmenopausal hormone therapy: The Heart and Estrogen/progestin Replacement Study. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 2003;138:1-9.
51. Cagnacci A, Soldani R, Carriero PL, Paoletti AM, Fioretti P, Melis GB. Effects of low doses of transdermal 17A-estradiol on carbohydrate metabolism in postmenopausal women. J Clin Endocrinol Metab 1992;74: 1396-1400.
52. Godsland IF. Oestrogens and insulin secretion. Diabetologia 2005;48: 2213-2220.
53. El Seifi S, Green IC, Perrin D. Insulin release and steroid-hormone binding in isolated islets of Langerhans in the rat: effects of ovariectomy. J Endocrinol 1981;90:59-67.
54. Tiano JP, Mauvais-Jarvis F. Importance of oestrogen receptors to preserve functional A-cell mass in diabetes. Nat Rev Endocrinol 2012;8:342-351.
55. Kahn SE, Andrikopoulos S, Verchere CB, Wang F, Hull RL, Vidal J. Oophorectomy promotes islet amyloid formation in a transgenic mouse model of type II diabetes. Diabetologia 2000;43:1309-1312.
56. Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, Unger RH. A-Cell lipotoxicity in the pathogenesis of nonYinsulin-dependent diabetes mellitus of obese rats: Impairment in adipocyteYA-cell relationships. Proc Natl Acad Sci U S A 1994;91:10878-10882.
57. Oyadomari S, Koizumi A, Takeda K, et al. Targeted disruption of the Chop gene delays endoplasmic reticulum stress mediated diabetes. J Clin Invest 2002;109:525-532.
58. NadalA, Rovira JM, Laribi O, et al. Rapid insulinotropic effect of 17A-estradiol via a plasma membrane receptor. FASEB J 1998;12:1341-1348.
59. Hussain MA, Porras DL, Rowe MH, et al. Increased pancreatic A-cell proliferation mediated by CREB binding protein gene activation. Mol Cell Biol 2006;26:7747-7759.
60. Otani K, Kulkarni RN, Baldwin AC, et al. Reduced A-cell mass and altered glucose sensing impair insulin-secretory function in AIRKO mice. Am J Physiol Endocrinol Metab 2004;286:E41-E49.
61. Shanik MH, Xu Y, Skrha J, Dankner R, Zick Y, Roth J. Insulin resistance and hyperinsulinemia: Is hyperinsulinemia the cart or the horse? Diabetes Care 2008;31(suppl 2):S262-S268.