-
1
-
-
0017890599
-
Purification of cyclic 3'5'-nucletoide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to sepharose
-
Klee CB, Krinks MH (1978). Purification of cyclic 3'5'-nucletoide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to sepharose. Biochemistry, 17: 120-126.
-
(1978)
Biochemistry
, vol.17
, pp. 120-126
-
-
Klee, C.B.1
Krinks, M.H.2
-
2
-
-
0001018554
-
Calcineurin - calcium-binding and calmodulin-binding protein of the nervous system
-
Klee CB, Crouch TH, Krinks MH (1979). Calcineurin - calcium-binding and calmodulin-binding protein of the nervous system. PNAS, 76: 6270-6273.
-
(1979)
PNAS
, vol.76
, pp. 6270-6273
-
-
Klee, C.B.1
Crouch, T.H.2
Krinks, M.H.3
-
3
-
-
0030887172
-
Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription
-
Yakel JL (1997). Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription. Trends Pharm. Sci., 18: 124-134.
-
(1997)
Trends Pharm. Sci.
, vol.18
, pp. 124-134
-
-
Yakel, J.L.1
-
4
-
-
0033779701
-
Calcineurin: form and function
-
Rusnak F, Mertz, P (2000). Calcineurin: form and function. Physiol. Rev., 80: 1483-1521.
-
(2000)
Physiol. Rev.
, vol.80
, pp. 1483-1521
-
-
Rusnak, F.1
Mertz, P.2
-
5
-
-
0025871394
-
Nuclear-association of a T-cell transcription factor blocked by FK-506 and cyclosporine-A
-
Flanagan WM, Corthesy B, Bram RJ, Crabtree GR (1991). Nuclear-association of a T-cell transcription factor blocked by FK-506 and cyclosporine-A. Nature, 352: 803-807.
-
(1991)
Nature
, vol.352
, pp. 803-807
-
-
Flanagan, W.M.1
Corthesy, B.2
Bram, R.J.3
Crabtree, G.R.4
-
6
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporine-A and FKBP-FK506 complexes
-
Liu J, Farmer JD, Lane WS, Friedman J, Weissman I, Schreiber SL (1991). Calcineurin is a common target of cyclophilin-cyclosporine-A and FKBP-FK506 complexes. Cell, 66: 807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
7
-
-
0026643141
-
Identification of calcineurin as a key signaling enzyme in lymphocyte-t activation
-
Clipstone NA, Crabtree GR (1992). Identification of calcineurin as a key signaling enzyme in lymphocyte-t activation. Nature, 357: 695-697.
-
(1992)
Nature
, vol.357
, pp. 695-697
-
-
Clipstone, N.A.1
Crabtree, G.R.2
-
8
-
-
0032540267
-
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
-
Molkentin JD, Lu JR, Antos CL, Markham B, Richardson J, Robbins J, Grant SR, Olson EN (1998). A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell, 93: 215-28.
-
(1998)
Cell
, vol.93
, pp. 215-228
-
-
Molkentin, J.D.1
Lu, J.R.2
Antos, C.L.3
Markham, B.4
Richardson, J.5
Robbins, J.6
Grant, S.R.7
Olson, E.N.8
-
9
-
-
0030463470
-
CREB phosphorylation and dephosphorylation: a Ca2(+)- and stimulus duration-dependent switch for hippocampcal gene expression
-
Bito H, Deisseroth K, Tsien RW (1996). CREB phosphorylation and dephosphorylation: a Ca2(+)- and stimulus duration-dependent switch for hippocampcal gene expression. Cell, 87: 1203-1214.
-
(1996)
Cell
, vol.87
, pp. 1203-1214
-
-
Bito, H.1
Deisseroth, K.2
Tsien, R.W.3
-
11
-
-
0033537768
-
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
Wang HG, Pathan N, Ethell IM, Krajewski S, Yamaguchi Y, Shibasaki F, McKeon F, Bobo T, Franke TF, Reed JC (1999). Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science, 284: 339-343.
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
12
-
-
0033607543
-
High level calcineurin activity predisposes neuronal cells to apoptosis
-
Asai A, Qiu J, Narita Y, Chi S, Saito N, Shinoura N, Hamada H, Kuchino Y, Kirino T (1999). High level calcineurin activity predisposes neuronal cells to apoptosis. J. Biol. Chem., 274: 34450-34458.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34450-34458
-
-
Asai, A.1
Qiu, J.2
Narita, Y.3
Chi, S.4
Saito, N.5
Shinoura, N.6
Hamada, H.7
Kuchino, Y.8
Kirino, T.9
-
13
-
-
0031596740
-
Involvement of calcineurin in Ca2+ paradox-like injury of cultured rat astrocytes
-
Matsuda T, Takuma K, Asano S, Kishida Y, Nakamura H, Mori K, Maeda S, Baba A (1998). Involvement of calcineurin in Ca2+ paradox-like injury of cultured rat astrocytes. J. Neurochem., 70: 2004-2011.
-
(1998)
J. Neurochem.
, vol.70
, pp. 2004-2011
-
-
Matsuda, T.1
Takuma, K.2
Asano, S.3
Kishida, Y.4
Nakamura, H.5
Mori, K.6
Maeda, S.7
Baba, A.8
-
14
-
-
77954755219
-
Microglial phenotype is regulated by activity of the transcription factor NFAT
-
Nagamoto-Combs K, Combs CK (2010). Microglial phenotype is regulated by activity of the transcription factor NFAT. J. Neurosci., 30: 9641-9646.
-
(2010)
J. Neurosci.
, vol.30
, pp. 9641-9646
-
-
Nagamoto-Combs, K.1
Combs, C.K.2
-
15
-
-
0030973579
-
Transcription factors of the NFAT family: regulation and function
-
Rao A, Luo C, Hogan PG (1997). Transcription factors of the NFAT family: regulation and function. Ann. Rev. of Immun., 15: 707-747.
-
(1997)
Ann. Rev. of Immun.
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
16
-
-
0028176087
-
Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression
-
Mulkey RM, Endo S, Shenolikar S, Malenka RC (1994). Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature, 369: 486-488.
-
(1994)
Nature
, vol.369
, pp. 486-488
-
-
Mulkey, R.M.1
Endo, S.2
Shenolikar, S.3
Malenka, R.C.4
-
17
-
-
0029055175
-
Oxidative processes and anti-oxidative defense mechanisms in the aging brain
-
Reiter RJ (1995). Oxidative processes and anti-oxidative defense mechanisms in the aging brain. FASEB J., 9: 526-533.
-
(1995)
FASEB J
, vol.9
, pp. 526-533
-
-
Reiter, R.J.1
-
18
-
-
0013784893
-
Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
-
Altman J, Das DG (1965). Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J. Compar. Neurol., 124: 319-336.
-
(1965)
J. Compar. Neurol.
, vol.124
, pp. 319-336
-
-
Altman, J.1
Das, D.G.2
-
19
-
-
0031789814
-
Neurogenesis in the adult human hippocampus
-
Eriksson PS, Perfilieva E, Bjork-Eriksson T, Alborn AM, Nordberg C, Peterson DA, Gage FH (1998). Neurogenesis in the adult human hippocampus. Nature Medicine, 4: 1313-1317.
-
(1998)
Nature Medicine
, vol.4
, pp. 1313-1317
-
-
Eriksson, P.S.1
Perfilieva, E.2
Bjork-Eriksson, T.3
Alborn, A.M.4
Nordberg, C.5
Peterson, D.A.6
Gage, F.H.7
-
20
-
-
0021943367
-
Reduced calcium-uptake by rat brain mitochondria and synaptosomes in response to aging
-
Leslie SW, Chandler LJ, Barr EM, Farrar RP (1985). Reduced calcium-uptake by rat brain mitochondria and synaptosomes in response to aging. Brain Res., 329, 177-183.
-
(1985)
Brain Res
, vol.329
, pp. 177-183
-
-
Leslie, S.W.1
Chandler, L.J.2
Barr, E.M.3
Farrar, R.P.4
-
21
-
-
0021645626
-
Prolonged Ca2+ dependent afterhyperpolarizations in hippocampal neurons of aged rats
-
Landfield PW, Pitler TA (1984). Prolonged Ca2+ dependent afterhyperpolarizations in hippocampal neurons of aged rats. Science, 226: 1089-1092.
-
(1984)
Science
, vol.226
, pp. 1089-1092
-
-
Landfield, P.W.1
Pitler, T.A.2
-
22
-
-
0024954411
-
Aging-related increases in voltage-sensitive, inactivating calcium currents in rat hippocampus Implications for mechanisms of brain aging and Alzheimer's disease
-
Landfield PW, Campbell LW, Hao SY, Kerr DS (1989). Aging-related increases in voltage-sensitive, inactivating calcium currents in rat hippocampus. Implications for mechanisms of brain aging and Alzheimer's disease. Ann. N. Y. Acad. Sci., 568: 95-105.
-
(1989)
Ann. N. Y. Acad. Sci.
, vol.568
, pp. 95-105
-
-
Landfield, P.W.1
Campbell, L.W.2
Hao, S.Y.3
Kerr, D.S.4
-
23
-
-
33645450459
-
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release
-
Gant JC, Sama MM, Landfield PW, Thibault O (2006). Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release. J. Neurosci., 26: 3482-3490.
-
(2006)
J. Neurosci.
, vol.26
, pp. 3482-3490
-
-
Gant, J.C.1
Sama, M.M.2
Landfield, P.W.3
Thibault, O.4
-
24
-
-
0015799240
-
Long-lasting potentiation of synaptic transmission in dentate area of anesthetized rabbit following stimulation of perforant path
-
Bliss TVP, Lømo T (1973). Long-lasting potentiation of synaptic transmission in dentate area of anesthetized rabbit following stimulation of perforant path. J. Physiol. - London, 232: 331-356.
-
(1973)
J. Physiol. - London
, vol.232
, pp. 331-356
-
-
Bliss, T.V.P.1
Lømo, T.2
-
25
-
-
0027476024
-
A synaptic model of memory - long term potentiation in the hippocampus
-
Bliss TVP, Collingridge GL (1993). A synaptic model of memory - long term potentiation in the hippocampus. Nature, 361: 31-39.
-
(1993)
Nature
, vol.361
, pp. 31-39
-
-
Bliss, T.V.P.1
Collingridge, G.L.2
-
26
-
-
49449096617
-
An allosteric model of calmodulin explains differential activation of PP2B and CaMKII
-
Stefan MI, Edelstein SJ, Novère NL (2008). An allosteric model of calmodulin explains differential activation of PP2B and CaMKII. Proc. Natl. Acad. Sci. U S A, 105: 10768-10773.
-
(2008)
Proc. Natl. Acad. Sci. U S A
, vol.105
, pp. 10768-10773
-
-
Stefan, M.I.1
Edelstein, S.J.2
Novère, N.L.3
-
27
-
-
34249051111
-
Calcium homeostasis and modulation of synaptic plasticity in the aged brain
-
Foster TC (2007). Calcium homeostasis and modulation of synaptic plasticity in the aged brain. Aging Cell, 6: 319-325.
-
(2007)
Aging Cell
, vol.6
, pp. 319-325
-
-
Foster, T.C.1
-
28
-
-
0033696622
-
Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD
-
Beattie EC, Carroll RC, Yu X, Morishita W, Yasuda H, von Zastrow M, Malenka RC (2000). Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nat. Neurosci., 3:1291-1300.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1291-1300
-
-
Beattie, E.C.1
Carroll, R.C.2
Yu, X.3
Morishita, W.4
Yasuda, H.5
von Zastrow, M.6
Malenka, R.C.7
-
29
-
-
0035354319
-
Calcineurin links Ca2+ dysregulation with brain aging
-
Foster TC, Sharrow KM, Masse JR, Norris CM, Kumar A (2001). Calcineurin links Ca2+ dysregulation with brain aging. J. Neurosci., 21: 4066-4073.
-
(2001)
J. Neurosci.
, vol.21
, pp. 4066-4073
-
-
Foster, T.C.1
Sharrow, K.M.2
Masse, J.R.3
Norris, C.M.4
Kumar, A.5
-
30
-
-
0037066075
-
Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture
-
Norris CM, Blalock EM, Chen KC, Porter NM, Landfield PW (2002). Calcineurin enhances L-type Ca(2+) channel activity in hippocampal neurons: increased effect with age in culture. Neuroscience, 110:213-225.
-
(2002)
Neuroscience
, vol.110
, pp. 213-225
-
-
Norris, C.M.1
Blalock, E.M.2
Chen, K.C.3
Porter, N.M.4
Landfield, P.W.5
-
31
-
-
71349085788
-
Hippocampal zipper' slice studies reveal a necessary role for calcineurin in the increased activity of Ltype Ca(2+) channels with aging
-
Norris CM, Blalock EM, Chen KC, Porter NM, Thibault O, Kraner SD, Landfield PW (2010). Hippocampal zipper' slice studies reveal a necessary role for calcineurin in the increased activity of Ltype Ca(2+) channels with aging. Neurobiol. Aging, 31: 328-338.
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 328-338
-
-
Norris, C.M.1
Blalock, E.M.2
Chen, K.C.3
Porter, N.M.4
Thibault, O.5
Kraner, S.D.6
Landfield, P.W.7
-
32
-
-
0032498227
-
Restricted an regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
-
Mansuy IM, Mayford M, Jacob B, Kandel ER, Bach ME (1998a). Restricted an regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell, 92: 39-49.
-
(1998)
Cell
, vol.92
, pp. 39-49
-
-
Mansuy, I.M.1
Mayford, M.2
Jacob, B.3
Kandel, E.R.4
Bach, M.E.5
-
33
-
-
0032144128
-
Inducible and reversible gene expression with the rtTA system for the study of memory
-
Mansuy IM, Winder DG, Moallem TM, Osman M, Mayford M, Hawkins RD, Kandel ER (1998b). Inducible and reversible gene expression with the rtTA system for the study of memory. Neuron, 21: 257-265.
-
(1998)
Neuron
, vol.21
, pp. 257-265
-
-
Mansuy, I.M.1
Winder, D.G.2
Moallem, T.M.3
Osman, M.4
Mayford, M.5
Hawkins, R.D.6
Kandel, E.R.7
-
34
-
-
0035977139
-
Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory
-
Zeng HK, Chattarji S, Barbarosie M, Rondi-Reig L, Philpot BD, Miyakawa T, Bear MF, Tonegawa S (2001). Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory. Cell, 107: 617-629.
-
(2001)
Cell
, vol.107
, pp. 617-629
-
-
Zeng, H.K.1
Chattarji, S.2
Barbarosie, M.3
Rondi-Reig, L.4
Philpot, B.D.5
Miyakawa, T.6
Bear, M.F.7
Tonegawa, S.8
-
35
-
-
0034124502
-
Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation
-
Ikegami S, Inokuchi K (2000). Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation. Neuroscience, 98:637-646.
-
(2000)
Neuroscience
, vol.98
, pp. 637-646
-
-
Ikegami, S.1
Inokuchi, K.2
-
36
-
-
0035831033
-
Inducible and reversible enhancement of learning, memory, and longterm potentiation by genetic inhibition of calcineurin
-
Malleret G, Haditsch U, Genoux D, Jones MW, Bliss TVP, Vanhoose AM, Weitlauf C, Kandel ER, Winder DG, Mansuy IM (2001). Inducible and reversible enhancement of learning, memory, and longterm potentiation by genetic inhibition of calcineurin. Cell, 104: 675-686.
-
(2001)
Cell
, vol.104
, pp. 675-686
-
-
Malleret, G.1
Haditsch, U.2
Genoux, D.3
Jones, M.W.4
Bliss, T.V.P.5
Vanhoose, A.M.6
Weitlauf, C.7
Kandel, E.R.8
Winder, D.G.9
Mansuy, I.M.10
-
37
-
-
33645022501
-
A role for the protein phosphatase 2B in altered hippocampal synaptic plasticity in the aged rat
-
Jouvenceau A, Dutar P (2006). A role for the protein phosphatase 2B in altered hippocampal synaptic plasticity in the aged rat. J. Physiol. Paris, 99: 154-161.
-
(2006)
J. Physiol. Paris
, vol.99
, pp. 154-161
-
-
Jouvenceau, A.1
Dutar, P.2
-
38
-
-
0030059338
-
Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity
-
Deisseroth K, Bito H, Tsien RW (1996). Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity. Neuron, 16: 89-101.
-
(1996)
Neuron
, vol.16
, pp. 89-101
-
-
Deisseroth, K.1
Bito, H.2
Tsien, R.W.3
-
39
-
-
0028176722
-
Characterization of Ca2+/calmodulin-dependent protein-kinase-IV role in transcriptional regulation
-
Enslen H, Sun PQ, Brickey D, Soderling SH, Klamo E, Soderling TR (1994). Characterization of Ca2+/calmodulin-dependent protein-kinase-IV role in transcriptional regulation. JBC, 22: 15520-15527.
-
(1994)
JBC
, vol.22
, pp. 15520-15527
-
-
Enslen, H.1
Sun, P.Q.2
Brickey, D.3
Soderling, S.H.4
Klamo, E.5
Soderling, T.R.6
-
40
-
-
0038198881
-
Neurons, glia, and plasticity in normal brain aging
-
Finch CE (2003). Neurons, glia, and plasticity in normal brain aging. Neurobiol. Aging., 24 [Suppl. 1]:S123-S127, S131.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. S123-S127
-
-
Finch, C.E.1
-
41
-
-
0035153212
-
Immune function of astrocytes
-
Dong YS, Benveniste EN (2001). Immune function of astrocytes. Glia, 36: 180-190.
-
(2001)
Glia
, vol.36
, pp. 180-190
-
-
Dong, Y.S.1
Benveniste, E.N.2
-
42
-
-
0025138986
-
Glutamate induces calcium waves in cultured astrocytes - long range glial signaling
-
Cornellbell AH, Finkbeiner SM, Cooper MS, Smith SJ (1990). Glutamate induces calcium waves in cultured astrocytes - long range glial signaling. Science, 247: 470-473.
-
(1990)
Science
, vol.247
, pp. 470-473
-
-
Cornellbell, A.H.1
Finkbeiner, S.M.2
Cooper, M.S.3
Smith, S.J.4
-
43
-
-
0026503603
-
Neuronal-activity triggers calcium waves in hippocampal astrocytes networks
-
Dani JW, Chernjavsky A, Smith SJ (1992). Neuronal-activity triggers calcium waves in hippocampal astrocytes networks. Neuron, 8: 429-440.
-
(1992)
Neuron
, vol.8
, pp. 429-440
-
-
Dani, J.W.1
Chernjavsky, A.2
Smith, S.J.3
-
44
-
-
0023032057
-
The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay
-
Goto S, Matsukado Y, Mihara Y, Inoue N, Miyamoto E (1986). The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay. Brain Res., 397: 161-172.
-
(1986)
Brain Res
, vol.397
, pp. 161-172
-
-
Goto, S.1
Matsukado, Y.2
Mihara, Y.3
Inoue, N.4
Miyamoto, E.5
-
45
-
-
18244391440
-
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models
-
Norris CM, Kadish I, Blalock EM, Chen KC, Thibault V, Porter NM, Landfield PW, Kraner SD (2005). Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. J. Neurosci., 25: 4649-4658.
-
(2005)
J. Neurosci.
, vol.25
, pp. 4649-4658
-
-
Norris, C.M.1
Kadish, I.2
Blalock, E.M.3
Chen, K.C.4
Thibault, V.5
Porter, N.M.6
Landfield, P.W.7
Kraner, S.D.8
-
46
-
-
0036234543
-
NFAT signaling: choreographing the social lives of cells
-
Crabtree GR, Olson EN (2002). NFAT signaling: choreographing the social lives of cells. Cell [Suppl], 109: S67-S79.
-
(2002)
Cell
, pp. S67-S79
-
-
Crabtree, G.R.1
Olson, E.N.2
-
47
-
-
0029851762
-
Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression
-
Timmerman LA, Clipstone NA, Ho SN, Northrop JP, Crabtree GR (1996). Rapid shuttling of NF-AT in discrimination of Ca2+ signals and immunosuppression. Nature, 383: 837-840.
-
(1996)
Nature
, vol.383
, pp. 837-840
-
-
Timmerman, L.A.1
Clipstone, N.A.2
Ho, S.N.3
Northrop, J.P.4
Crabtree, G.R.5
-
48
-
-
42549155189
-
Mechanical lesion activates newly identified NFATc1 in primary astrocytes: implication of ATP and purinergic receptors
-
Pérez-Ortiz JM, Serrano-Pérez MC, Pastor MD, Martín ED, Calvo S, Rincón M, Tranque P (2008). Mechanical lesion activates newly identified NFATc1 in primary astrocytes: implication of ATP and purinergic receptors. Eur. J. Neurosci., 27: 2453-2465.
-
(2008)
Eur. J. Neurosci.
, vol.27
, pp. 2453-2465
-
-
Pérez-Ortiz, J.M.1
Serrano-Pérez, M.C.2
Pastor, M.D.3
Martín, E.D.4
Calvo, S.5
Rincón, M.6
Tranque, P.7
-
49
-
-
52049094598
-
Interleukin-1 beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity
-
Sama MA, Mathis DM, Furman JL, Abdul HM, Artiushin LA, Kraner SD, Norris CM (2008). Interleukin-1 beta-dependent signaling between astrocytes and neurons depends critically on astrocytic calcineurin/NFAT activity. JBC, 283: 21953-21964.
-
(2008)
JBC
, vol.283
, pp. 21953-21964
-
-
Sama, M.A.1
Mathis, D.M.2
Furman, J.L.3
Abdul, H.M.4
Artiushin, L.A.5
Kraner, S.D.6
Norris, C.M.7
-
50
-
-
70350454809
-
Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling
-
Abdul HM, Sama MA, Furman JL, Mathis DM, Beckett TL, Weidner AM, Patel ES, Baig I, Murphy MP, LeVine H, Kraner SD, Norris CM (2009). Cognitive decline in Alzheimer's disease is associated with selective changes in calcineurin/NFAT signaling. J. Neurosci., 29: 12957-12969.
-
(2009)
J. Neurosci.
, vol.29
, pp. 12957-12969
-
-
Abdul, H.M.1
Sama, M.A.2
Furman, J.L.3
Mathis, D.M.4
Beckett, T.L.5
Weidner, A.M.6
Patel, E.S.7
Baig, I.8
Murphy, M.P.9
LeVine, H.10
Kraner, S.D.11
Norris, C.M.12
-
51
-
-
0032937860
-
The role of microglia and macrophages in the pathophysiology of the CNS
-
Stoll G, Jander S (1999). The role of microglia and macrophages in the pathophysiology of the CNS. Prog. Neurobiol., 58: 233-247.
-
(1999)
Prog. Neurobiol.
, vol.58
, pp. 233-247
-
-
Stoll, G.1
Jander, S.2
-
53
-
-
5344277556
-
Deciphering the molecular basis of memory failure in Alzheimer's disease
-
Walsh DM, Selkoe DJ (2004). Deciphering the molecular basis of memory failure in Alzheimer's disease. Neuron, 44: 181-193.
-
(2004)
Neuron
, vol.44
, pp. 181-193
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
54
-
-
0027508926
-
Alzheimer-disease amyloid beta-protein forms calcium channels in bilayer membranes - blockade by tromethamine and aluminum
-
Arispe N, Rojas R, Pollard HB (1993). Alzheimer-disease amyloid beta-protein forms calcium channels in bilayer membranes - blockade by tromethamine and aluminum. PNAS, 90: 567-571.
-
(1993)
PNAS
, vol.90
, pp. 567-571
-
-
Arispe, N.1
Rojas, R.2
Pollard, H.B.3
-
55
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
Demuro A, Mina E, Kayed R, Milton SC, Parker I, Glabe CG (2005). Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J. Biol. Chem., 280: 17294-17300.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
56
-
-
0037363599
-
Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides
-
Agostinho P, Oliveira C (2003). Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides. Eur. J. Neurosci., 17: 1189-1196.
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 1189-1196
-
-
Agostinho, P.1
Oliveira, C.2
-
57
-
-
56849091064
-
Selective induction of calcineurin activity and signaling by oligomeric amyloid beta
-
Reese LC, Zhang W, Dineley KT, Kayed R, Taglialatela G (2008). Selective induction of calcineurin activity and signaling by oligomeric amyloid beta. Aging Cell, 7: 824-835.
-
(2008)
Aging Cell
, vol.7
, pp. 824-835
-
-
Reese, L.C.1
Zhang, W.2
Dineley, K.T.3
Kayed, R.4
Taglialatela, G.5
-
58
-
-
47749113650
-
A beta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks
-
Kuchibhotla KV, Goldman ST, Lattarulo CR, Wu HY, Hyman BT, Bacskai BJ (2008). A beta plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks. Neuron, 59: 214-225.
-
(2008)
Neuron
, vol.59
, pp. 214-225
-
-
Kuchibhotla, K.V.1
Goldman, S.T.2
Lattarulo, C.R.3
Wu, H.Y.4
Hyman, B.T.5
Bacskai, B.J.6
-
59
-
-
0038222585
-
AMPA receptor trafficking and long-term potentiation
-
Malinow R (2003). AMPA receptor trafficking and long-term potentiation. Philos. Trans. R. Soc. Lond. B. Biol. Sci., 358: 707-714.
-
(2003)
Philos. Trans. R. Soc. Lond. B. Biol. Sci.
, vol.358
, pp. 707-714
-
-
Malinow, R.1
-
60
-
-
0038125598
-
Calcium signalling: dynamics, homeostasis and remodelling
-
Berridge MJ, Bootman MD, Roderick HL (2003). Calcium signalling: dynamics, homeostasis and remodelling. Nat. Rev. Mol. Cell Biol., 4: 517-529.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 517-529
-
-
Berridge, M.J.1
Bootman, M.D.2
Roderick, H.L.3
-
61
-
-
0027474051
-
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer-disease - a potential molecular basis for neuronal degeneration
-
Saito KI, Elce JS, Hamose JE, Nixon RA (1993). Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer-disease - a potential molecular basis for neuronal degeneration. PNAS, 90: 2628-2632.
-
(1993)
PNAS
, vol.90
, pp. 2628-2632
-
-
Saito, K.I.1
Elce, J.S.2
Hamose, J.E.3
Nixon, R.A.4
-
62
-
-
27844553889
-
Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain
-
Liu F, Grundke-Iqbal I, Iqbal K, Oda Y, Tomizawa K, Gong CX (2005). Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J. Biol. Chem., 280: 37755-37762.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37755-37762
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Oda, Y.4
Tomizawa, K.5
Gong, C.X.6
-
63
-
-
77249158836
-
Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation
-
Wu HY, Hudry E, Hashimoto T, Kuchibhotla K, Rozkaine A, Fan Z, Spires-Jones T, Xie H, Arbel- Ornath M, Grosskreutz CL, Bacskai BJ, Hyman BT (2010). Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation. J. Neurosci., 30: 2636-2649.
-
(2010)
J. Neurosci.
, vol.30
, pp. 2636-2649
-
-
Wu, H.Y.1
Hudry, E.2
Hashimoto, T.3
Kuchibhotla, K.4
Rozkaine, A.5
Fan, Z.6
Spires-Jones, T.7
Xie, H.8
Arbel-Ornath, M.9
Grosskreutz, C.L.10
Bacskai, B.J.11
Hyman, B.T.12
-
64
-
-
0032535029
-
Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type
-
Bi G, Poo M (1998). Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J. Neurosci.,18: 10464-10472.
-
(1998)
J. Neurosci
, vol.18
, pp. 10464-10472
-
-
Bi, G.1
Poo, M.2
-
65
-
-
0042838303
-
Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
Gong YS, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE, Krafft GA, Klein WL (2003). Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc. Nat. Acad. Sci. U.S.A., 100: 10417-10422.
-
(2003)
Proc. Nat. Acad. Sci. U. S. A.
, vol.100
, pp. 10417-10422
-
-
Gong, Y.S.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
Krafft, G.A.7
Klein, W.L.8
-
66
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong YS, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL (2004). Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J. Neurosci., 24: 10191-10200.
-
(2004)
J. Neurosci.
, vol.24
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.S.5
Viola, K.L.6
Lambert, M.P.7
Velasco, P.T.8
Bigio, E.H.9
Finch, C.E.10
Krafft, G.A.11
Klein, W.L.12
-
67
-
-
33846633336
-
A beta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
-
Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL (2007). A beta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J. Neurosci., 27: 796-807.
-
(2007)
J. Neurosci.
, vol.27
, pp. 796-807
-
-
Lacor, P.N.1
Buniel, M.C.2
Furlow, P.W.3
Clemente, A.S.4
Velasco, P.T.5
Wood, M.6
Viola, K.L.7
Klein, W.L.8
-
68
-
-
14844315768
-
Amyloid β prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation
-
Zhao D, Watson JB, Xie CW (2004). Amyloid β prevents activation of calcium/calmodulin-dependent protein kinase II and AMPA receptor phosphorylation during hippocampal long-term potentiation. J. Neurophysiol., 92, 2853-2858.
-
(2004)
J. Neurophysiol.
, vol.92
, pp. 2853-2858
-
-
Zhao, D.1
Watson, J.B.2
Xie, C.W.3
-
69
-
-
0036354603
-
Alzheimer amyloid b-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus
-
Chen QS, Wei WZ, Shimahara T, Xie CW (2002). Alzheimer amyloid b-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus. Neurobiol. Learn. Mem., 77: 354-371.
-
(2002)
Neurobiol. Learn. Mem.
, vol.77
, pp. 354-371
-
-
Chen, Q.S.1
Wei, W.Z.2
Shimahara, T.3
Xie, C.W.4
-
70
-
-
77957233071
-
Amyloid beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice
-
ePub ahead of print: 11 June 2010
-
Dineley KT, Kayed R, Neugebauer V, Fu Y, Zhang W, Reese LC, Taglialatela G (2010). Amyloid beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice. J. Neurosci. Res., ePub ahead of print: 11 June 2010.
-
(2010)
J. Neurosci. Res.
-
-
Dineley, K.T.1
Kayed, R.2
Neugebauer, V.3
Fu, Y.4
Zhang, W.5
Reese, L.C.6
Taglialatela, G.7
-
71
-
-
33746210815
-
Partial inhibition of PP1 alters bidirectional synaptic plasticity in the hippocampus
-
Jouvenceau, A, Hédou G, Potier B, Kollen M, Dutar P, Mansuy M (2006). Partial inhibition of PP1 alters bidirectional synaptic plasticity in the hippocampus. Eur. J. Neurosci., 24: 564-572.
-
(2006)
Eur. J. Neurosci.
, vol.24
, pp. 564-572
-
-
Jouvenceau, A.1
Hédou, G.2
Potier, B.3
Kollen, M.4
Dutar, P.5
Mansuy, M.6
-
72
-
-
33947314641
-
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDAtype glutamate receptor-dependent signaling pathway
-
Shankar GM, Bloodgood BL, Townsend M, Walsh DM, Selkoe DJ, Sabatini BL (2007). Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDAtype glutamate receptor-dependent signaling pathway. J. Neurosci., 27: 2866-2875.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2866-2875
-
-
Shankar, G.M.1
Bloodgood, B.L.2
Townsend, M.3
Walsh, D.M.4
Selkoe, D.J.5
Sabatini, B.L.6
-
73
-
-
34547653708
-
Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice
-
Dineley KT, Hogan D, Zhang WR, Taglialatela G (2007). Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice. Neurobiol. Learn. Mem., 88: 217-224.
-
(2007)
Neurobiol. Learn. Mem.
, vol.88
, pp. 217-224
-
-
Dineley, K.T.1
Hogan, D.2
Zhang, W.R.3
Taglialatela, G.4
-
74
-
-
62649147319
-
Intermediate and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition. Behav
-
Taglialatela G, Hogan D, Zhang WR, Dineley KT (2009). Intermediate and long-term recognition memory deficits in Tg2576 mice are reversed with acute calcineurin inhibition. Behav. Brain Res., 200:95-99.
-
(2009)
Brain Res
, vol.200
, pp. 95-99
-
-
Taglialatela, G.1
Hogan, D.2
Zhang, W.R.3
Dineley, K.T.4
-
75
-
-
0033541589
-
Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type
-
Yamamoto-Sasaki M, Ozawa H, Saito T, Rosler M, Riederer P (1999). Impaired phosphorylation of cyclic AMP response element binding protein in the hippocampus of dementia of the Alzheimer type. Brain Res., 824: 300-303.
-
(1999)
Brain Res
, vol.824
, pp. 300-303
-
-
Yamamoto-Sasaki, M.1
Ozawa, H.2
Saito, T.3
Rosler, M.4
Riederer, P.5
-
76
-
-
77049085956
-
Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain
-
Simpson JE, Ince PG, Lace G, Forster G, Shaw PJ, Matthews F, Savva G, Brayne C, Wharton SB (2010). Astrocyte phenotype in relation to Alzheimer-type pathology in the ageing brain. Neurobiol. of Aging, 31: 578-590.
-
(2010)
Neurobiol. of Aging
, vol.31
, pp. 578-590
-
-
Simpson, J.E.1
Ince, P.G.2
Lace, G.3
Forster, G.4
Shaw, P.J.5
Matthews, F.6
Savva, G.7
Brayne, C.8
Wharton, S.B.9
-
77
-
-
0027257708
-
Apoptosis is induced by beta-amyloid in cultured central nervous system neurons
-
Loo DT, Copani A, Pike CJ, Whittemore ER, Walencewicz AJ, Cotman CW (1993). Apoptosis is induced by beta-amyloid in cultured central nervous system neurons. PNAS, 90: 7951-7955.
-
(1993)
PNAS
, vol.90
, pp. 7951-7955
-
-
Loo, D.T.1
Copani, A.2
Pike, C.J.3
Whittemore, E.R.4
Walencewicz, A.J.5
Cotman, C.W.6
-
78
-
-
40949104298
-
Overactivation of calcineurin induced by amyloid-beta and prion proteins
-
Agostinho P, Lopes JP, Velez Z, Oliveira CR (2008). Overactivation of calcineurin induced by amyloid-beta and prion proteins. Neurochem. Intl., 52: 1226-1233.
-
(2008)
Neurochem. Intl.
, vol.52
, pp. 1226-1233
-
-
Agostinho, P.1
Lopes, J.P.2
Velez, Z.3
Oliveira, C.R.4
-
79
-
-
0037417238
-
Memantine in moderate to severe AD.
-
Reisberg B, Doody R, Stoffler A, Schmitt F, Ferris S, Mobius HJ (2003). Memantine in moderate to severe AD. NEJM, 348: 1333-1341.
-
(2003)
NEJM
, vol.348
, pp. 1333-1341
-
-
Reisberg, B.1
Doody, R.2
Stoffler, A.3
Schmitt, F.4
Ferris, S.5
Mobius, H.J.6
-
80
-
-
0029811901
-
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies
-
McGeer PL, Schulzer M, McGeer EG (1996). Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology, 47: 425-432.
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
81
-
-
0030897133
-
Risk of Alzheimer's disease and duration of NSAID use
-
Stewart WF, Kawas C, Corrada M, Metter EJ (1997). Risk of Alzheimer's disease and duration of NSAID use. Neurology, 48: 626-632.
-
(1997)
Neurology
, vol.48
, pp. 626-632
-
-
Stewart, W.F.1
Kawas, C.2
Corrada, M.3
Metter, E.J.4
-
82
-
-
77949892665
-
Non-steroidal anti-inflammatory drugs and Alzheimer's disease: the epidemiological evidence
-
Szekely CA, Zandi PP (2010). Non-steroidal anti-inflammatory drugs and Alzheimer's disease: the epidemiological evidence. CNS & Neurol. Disorders - Drug Targets, 9: 132-139.
-
(2010)
CNS & Neurol. Disorders - Drug Targets
, vol.9
, pp. 132-139
-
-
Szekely, C.A.1
Zandi, P.P.2
-
83
-
-
0034604683
-
An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes
-
Iniguez MA, Martinez-Martinez S, Punzon C, Redondo JM, Fresno M (2000). An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. JBC, 275: 23627-23635.
-
(2000)
JBC
, vol.275
, pp. 23627-23635
-
-
Iniguez, M.A.1
Martinez-Martinez, S.2
Punzon, C.3
Redondo, J.M.4
Fresno, M.5
|