-
1
-
-
0037363599
-
Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides
-
Agostinho P., and Oliveira C.R. Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides. Eur. J. Neurosci. 17 (2003) 1189-1196
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 1189-1196
-
-
Agostinho, P.1
Oliveira, C.R.2
-
2
-
-
0242300624
-
Games played by rogue proteins in prion disorders and Alzheimer's disease
-
Aguzzi A., and Haass C. Games played by rogue proteins in prion disorders and Alzheimer's disease. Science 302 (2003) 814-818
-
(2003)
Science
, vol.302
, pp. 814-818
-
-
Aguzzi, A.1
Haass, C.2
-
3
-
-
33746304427
-
Delineating common molecular mechanisms in Alzheimer's and prion diseases
-
Barnham K.J., Cappai R., Beyreuther K., Masters C.L., and Hill A.F. Delineating common molecular mechanisms in Alzheimer's and prion diseases. Trends Biochem. Sci. 31 (2006) 465-472
-
(2006)
Trends Biochem. Sci.
, vol.31
, pp. 465-472
-
-
Barnham, K.J.1
Cappai, R.2
Beyreuther, K.3
Masters, C.L.4
Hill, A.F.5
-
4
-
-
33646728858
-
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity
-
Biasini E., Massignan T., Fioriti L., Rossi V., Dossena S., Salmona M., Forloni G., Bonetto V., and Chiesa R. Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity. Proteomics 6 (2006) 2823-2834
-
(2006)
Proteomics
, vol.6
, pp. 2823-2834
-
-
Biasini, E.1
Massignan, T.2
Fioriti, L.3
Rossi, V.4
Dossena, S.5
Salmona, M.6
Forloni, G.7
Bonetto, V.8
Chiesa, R.9
-
5
-
-
0242437802
-
Calcineurin and intracellular Ca2+-release channels: regulation or association?
-
Bultynck G., Vermassen E., Szlufcik K., De Smet P., Fissore R.A., Callewaert G., Missiaen L., De Smedt H., and Parys J.B. Calcineurin and intracellular Ca2+-release channels: regulation or association?. Biochem. Biophys. Res. Commun. 311 (2003) 1181-1193
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.311
, pp. 1181-1193
-
-
Bultynck, G.1
Vermassen, E.2
Szlufcik, K.3
De Smet, P.4
Fissore, R.A.5
Callewaert, G.6
Missiaen, L.7
De Smedt, H.8
Parys, J.B.9
-
6
-
-
0033811168
-
A modulatory role for protein phosphatase 2B (calcineurin) in the regulation of Ca2+ entry
-
Burley J.R., and Sihra T.S. A modulatory role for protein phosphatase 2B (calcineurin) in the regulation of Ca2+ entry. Eur. J. Neurosci. 12 (2000) 2881-2891
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 2881-2891
-
-
Burley, J.R.1
Sihra, T.S.2
-
7
-
-
21544459062
-
The role of calcineurin in amyloid-beta-peptides-mediated cell death
-
Cardoso S.M., and Oliveira C.R. The role of calcineurin in amyloid-beta-peptides-mediated cell death. Brain Res. 1050 (2005) 1-7
-
(2005)
Brain Res.
, vol.1050
, pp. 1-7
-
-
Cardoso, S.M.1
Oliveira, C.R.2
-
8
-
-
33845286140
-
Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis
-
Carter C.J. Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis. Neurochem. Int. 50 (2007) 12-38
-
(2007)
Neurochem. Int.
, vol.50
, pp. 12-38
-
-
Carter, C.J.1
-
9
-
-
34147112878
-
Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress
-
Celsi F., Svedberg M., Unger C., Cotman C.W., Carri M.T., Ottersen O.P., Nordberg A., and Torp R. Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress. Neurobiol. Dis. 26 (2007) 342-352
-
(2007)
Neurobiol. Dis.
, vol.26
, pp. 342-352
-
-
Celsi, F.1
Svedberg, M.2
Unger, C.3
Cotman, C.W.4
Carri, M.T.5
Ottersen, O.P.6
Nordberg, A.7
Torp, R.8
-
10
-
-
37649000487
-
Molecular architecture of human prion protein amyloid: a parallel, in-register beta-structure
-
Cobb N.J., Sönnichsen F.D., McHaourab H., and Surewicz W.K. Molecular architecture of human prion protein amyloid: a parallel, in-register beta-structure. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 8946-8951
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 8946-8951
-
-
Cobb, N.J.1
Sönnichsen, F.D.2
McHaourab, H.3
Surewicz, W.K.4
-
11
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
Demuro A., Mina E., Kayed R., Milton S.C., Parker I., and Glabe C.G. Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers. J. Biol. Chem. 280 (2005) 17294-17300
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
12
-
-
34547653708
-
Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice
-
Dineley K.T., Hogan D., Zhang W.R., and Taglialatela G. Acute inhibition of calcineurin restores associative learning and memory in Tg2576 APP transgenic mice. Neurobiol. Learn. Mem. 88 (2007) 217-224
-
(2007)
Neurobiol. Learn. Mem.
, vol.88
, pp. 217-224
-
-
Dineley, K.T.1
Hogan, D.2
Zhang, W.R.3
Taglialatela, G.4
-
13
-
-
33747195017
-
An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity
-
Ferreiro E., Resende R., Costa R., Oliveira C.R., and Pereira C.M. An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity. Neurobiol. Dis. 23 (2006) 669-678
-
(2006)
Neurobiol. Dis.
, vol.23
, pp. 669-678
-
-
Ferreiro, E.1
Resende, R.2
Costa, R.3
Oliveira, C.R.4
Pereira, C.M.5
-
15
-
-
0036861662
-
The pathogenic mechanisms of prion diseases
-
Hur K., Kim J.I., Choi S.I., Choi E.K., Carp R.I., and Kim Y.S. The pathogenic mechanisms of prion diseases. Mech. Ageing Dev. 123 (2002) 1637-1647
-
(2002)
Mech. Ageing Dev.
, vol.123
, pp. 1637-1647
-
-
Hur, K.1
Kim, J.I.2
Choi, S.I.3
Choi, E.K.4
Carp, R.I.5
Kim, Y.S.6
-
16
-
-
22144492630
-
Disruption of calcium homeostasis in the pathogenesis of Alzheimer's disease and other conformational diseases
-
Kawahara M. Disruption of calcium homeostasis in the pathogenesis of Alzheimer's disease and other conformational diseases. Curr. Alzheimer Res. 1 (2004) 87-95
-
(2004)
Curr. Alzheimer Res.
, vol.1
, pp. 87-95
-
-
Kawahara, M.1
-
17
-
-
33751513394
-
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
-
Kim H., Rafiuddin-Shah M., Tu H.C., Jeffers J.R., Zambetti G.P., Hsieh J.J., and Cheng E.H. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies. Nat. Cell Biol. 8 (2006) 1348-1358
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1348-1358
-
-
Kim, H.1
Rafiuddin-Shah, M.2
Tu, H.C.3
Jeffers, J.R.4
Zambetti, G.P.5
Hsieh, J.J.6
Cheng, E.H.7
-
18
-
-
0036830947
-
Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease
-
LaFerla F.M. Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease. Nat. Rev. Neurosci. 3 (2002) 862-872
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 862-872
-
-
LaFerla, F.M.1
-
19
-
-
27844553889
-
Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain
-
Liu F., Grundke-Iqbal I., Iqbal K., Oda Y., Tomizawa K., and Gong C.X. Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. J. Biol. Chem. 280 (2005) 37755-37762
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37755-37762
-
-
Liu, F.1
Grundke-Iqbal, I.2
Iqbal, K.3
Oda, Y.4
Tomizawa, K.5
Gong, C.X.6
-
20
-
-
0242690133
-
Calcineurin in memory and bidirectional plasticity
-
Mansuy I.M. Calcineurin in memory and bidirectional plasticity. Biochem. Biophys. Res. Commun. 311 (2003) 1195-1208
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.311
, pp. 1195-1208
-
-
Mansuy, I.M.1
-
21
-
-
36849023935
-
Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders
-
Marks N., and Berg M.J. Neurosecretases provide strategies to treat sporadic and familial Alzheimer disorders. Neurochem. Int. 52 (2008) 184-215
-
(2008)
Neurochem. Int.
, vol.52
, pp. 184-215
-
-
Marks, N.1
Berg, M.J.2
-
22
-
-
33947623671
-
Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders
-
Mattson M.P. Neuronal life-and-death signaling, apoptosis, and neurodegenerative disorders. Antioxid. Redox. Signal. 8 (2006) 1997-2006
-
(2006)
Antioxid. Redox. Signal.
, vol.8
, pp. 1997-2006
-
-
Mattson, M.P.1
-
23
-
-
33744982670
-
Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice
-
Morgan D. Modulation of microglial activation state following passive immunization in amyloid depositing transgenic mice. Neurochem. Int. 49 (2006) 190-194
-
(2006)
Neurochem. Int.
, vol.49
, pp. 190-194
-
-
Morgan, D.1
-
24
-
-
18244391440
-
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models
-
Norris C.M., Kadish I., Blalock E.M., Chen K.C., Thibault V., Porter N.M., Landfield P.W., and Kraner S.D. Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models. J. Neurosci. 25 (2005) 4649-4658
-
(2005)
J. Neurosci.
, vol.25
, pp. 4649-4658
-
-
Norris, C.M.1
Kadish, I.2
Blalock, E.M.3
Chen, K.C.4
Thibault, V.5
Porter, N.M.6
Landfield, P.W.7
Kraner, S.D.8
-
25
-
-
1542395816
-
Therapeutic implications for immunophilin ligands in the treatment of neurodegenerative diseases
-
Pong K., and Zaleska M.M. Therapeutic implications for immunophilin ligands in the treatment of neurodegenerative diseases. Curr. Drug Targets CNS Neurol. Disord. 2 (2003) 349-356
-
(2003)
Curr. Drug Targets CNS Neurol. Disord.
, vol.2
, pp. 349-356
-
-
Pong, K.1
Zaleska, M.M.2
-
26
-
-
0032142911
-
Immunophilins in the nervous system
-
Snyder S.H., Lai M.M., and Burnett P.E. Immunophilins in the nervous system. Neuron 21 (1998) 283-294
-
(1998)
Neuron
, vol.21
, pp. 283-294
-
-
Snyder, S.H.1
Lai, M.M.2
Burnett, P.E.3
-
27
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-beta
-
Snyder E.M., Nong Y., Almeida C.G., Paul S., Moran T., Choi E.Y., Nairn A.C., Salter M.W., Lombroso P.J., Gouras G.K., and Greengard P. Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci. 8 (2005) 1051-1058
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
Greengard, P.11
-
28
-
-
0033044804
-
Alzheimer's and prion disease as disorders of protein conformation: implications for the design of novel therapeutic approaches
-
Soto C. Alzheimer's and prion disease as disorders of protein conformation: implications for the design of novel therapeutic approaches. J. Mol. Med. 77 (1999) 412-418
-
(1999)
J. Mol. Med.
, vol.77
, pp. 412-418
-
-
Soto, C.1
-
29
-
-
0034307421
-
Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury
-
Springer J.E., Azbill R.D., Nottingham S.A., and Kennedy S.E. Calcineurin-mediated BAD dephosphorylation activates the caspase-3 apoptotic cascade in traumatic spinal cord injury. J. Neurosci. 20 (2000) 7246-7251
-
(2000)
J. Neurosci.
, vol.20
, pp. 7246-7251
-
-
Springer, J.E.1
Azbill, R.D.2
Nottingham, S.A.3
Kennedy, S.E.4
-
30
-
-
0033537768
-
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
Wang H.G., Pathan N., Ethell I.M., Krajewski S., Yamaguchi Y., Shibasaki F., McKeon F., Bobo T., Franke T.F., and Reed J.C. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science 284 (1999) 339-343
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
31
-
-
34447629569
-
Therapeutic approaches for prion and Alzheimer's diseases
-
Wisniewski T., and Sigurdsson E.M. Therapeutic approaches for prion and Alzheimer's diseases. FEBS J. 274 (2007) 3784-3798
-
(2007)
FEBS J.
, vol.274
, pp. 3784-3798
-
-
Wisniewski, T.1
Sigurdsson, E.M.2
|