Partial inhibition of PP1 alters bidirectional synaptic plasticity in the hippocampus

European Journal of Neuroscience

Volumn 24, Issue 2, 2006, Pages 564-572

  Jouvenceau, Anne ^a,b,d   Hédou, Gael ^c,e   Potier, Brigitte ^a,b   Kollen, Mélanie ^a,b   Dutar, Patrick ^a,b   Mansuy, Isabelle M ^c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c University of Zurich Brain Research Institute   (Switzerland)

^d CENTRE PAUL BROCA   (France)

^e GSK   (Italy)

Author keywords

Depotentiation; Inhibitor 1; Long term depression; Long term potentiation; Mouse hippocampus; Protein phosphatase 1

Indexed keywords

PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME INHIBITION; FOREBRAIN; HIPPOCAMPUS; LEARNING; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

ACTION POTENTIALS; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; ELECTRIC STIMULATION; ENZYME INHIBITORS; HIPPOCAMPUS; LONG-TERM DEPRESSION (PHYSIOLOGY); LONG-TERM POTENTIATION; MICE; MICE, TRANSGENIC; MUTATION; NEURONAL PLASTICITY; ORGAN CULTURE TECHNIQUES; PHOSPHOPROTEIN PHOSPHATASE; PRESYNAPTIC TERMINALS; SYNAPTIC TRANSMISSION;

EID: 33746210815     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.04938.x     Document Type: Article

References (30)

1. Allen, P.B., Hvalby, O., Jensen, V., Errington, M.L., Ramsay, M., Chaudhry, F.A., Bliss, T.V., Storm-Mathisen, J., Morris, R.G., Andersen, P. & Greengard, P. (2000) Protein phosphatase-1 regulation in the induction of long-term potentiation: heterogeneous molecular mechanisms. J. Neurosci., 20, 3537-3543.
2. Bear, M.F. & Abraham, W.C. (1996) Long term depression in hippocampus. Annu. Rev. Neurosci., 19, 437-462.
3. Beattie, E.C. & Carroll, R.C., Yu, X., Morishita, W., Yasuda, H., Von Zastrow, M. & Malenka, R.C. (2000) Regulation of AMPA receptor endocytosis by a signalling mechanism shared with LTD. Nat. Neurosci., 3, 1291-1300.
4. Blitzer, R.D., Connor, J.H., Brown, G.P., Wong, T., Shenolikar, S., Iyengar, R. & Landau, E.M. (1998) Gating of CaMKII by cAMP-regulated protein phosphatase activity during LTP. Science, 280, 1940-1942.
5. 2+/calmodulin-dependent protein kinase II-protein phosphatase 1 switch facilitates specificity in postsynaptic calcium signaling. Proc. Natl Acad. Sci. USA, 100, 10512-10517.
6. Ceulemans, H. & Bollen, M. (2004) Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol. Rev., 84, 1-39.
7. Colbran, R.J. & Brown, A.M. (2004) Calcium/calmodulin-dependent protein kinase II and synaptic plasticity. Curr. Opin. Neurobiol., 14, 318-327.
8. Ehlers, M.D. (2000) Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron, 28, 511-525.
9. Esteban, J.A., Shi, S.H., Wilson, C., Nuriya, M., Huganir, R.L. & Malinow, R. (2003) PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nat. Neurosci., 6, 136-143.
10. Feng, J., Yan, Z., Ferreira, A., Tomizawa, K., Liauw, J.A., Zhuo, M., Allen, P.B., Ouimet, C.C. & Greengard, P. (2000) Spinophilin regulates the formation and function of dendritic spines. Proc. Natl Acad. Sci. USA, 97, 9287-9292.
11. Genoux, D., Haditsch, U., Knobloch, M., Michalon, A., Storm, D. & Mansuy, I.M. (2002) Protein phosphatase 1 is a molecular constraint on learning and memory. Nature, 418, 970-975.
12. Gibbons, J.A., Weiser, D.C. & Shenolikar, S. (2005) Importance of a surface hydrophobic pocket on protein phosphatase-1 catalytic subunit in recognizing cellular regulators. J. Biol. Chem., 280, 15903-15911.
13. Greengard, P., Allen, P.B. & Nairn, A.C. (1999) Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade. Neuron, 23, 435-447.
14. Huang, C.C. & Hsu, K.S. (2001) Progress in understanding the factors regulating reversibility of long-term potentiation. Rev. Neurosci., 12, 51-68.
15. Isaac, J. (2001) Protein phosphatase 1 and LTD: synapses are the architects of depression. Neuron, 32, 963-966.
16. Jouvenceau, A., Billard, J.M., Haditsch, U., Mansuy, I.M. & Dutar, P. (2003) Different phosphatase-dependent mechanisms mediate long-term depression and depotentiation of long-term potentiation in mouse hippocampal CA1 area. Eur. J. Neurosci., 18, 1279-1285.
17. Kahana, M.J., Seelig, D. & Madsen, J.R. (2001) Theta returns. Curr. Opin. Neurobiol., 11, 739-744.
18. 2+ and short-term synaptic plasticity. Nature, 371, 603-606.
19. Lisman, J. (1989) A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory. Proc. Natl Acad. Sci. USA, 86, 9574-9578.
20. 2+/calmodulin-dependent kinase II autophosphorylation. J. Neurosci., 19, 2500-2510.
21. Malenka, R., Kauer, J., Perkel, D., Mauk, M. & Kelly, P. (1989) An essential role for postsynaptic calmodulin and protein kinase activity in long term potentiation. Nature, 340, 554-557.
22. Morishita, W., Connor, J.H., Xia, H., Quinlan, E.M., Shenolikar, S. & Malenka, R.C. (2001) Regulation of synaptic strength by protein phosphatase 1. Neuron, 32, 1133-1148.
23. Morishita, W., Marie, H. & Malenka, R.C. (2005) Distinct triggering and expression mechanisms underlie LTD of AMPA and NMDA synaptic responses. Nat. Neurosci., 8, 1043-1050.
24. Mulkey, R.M., Endo, S., Shenolikar, S. & Malenka, R.C. (1994) Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression. Nature, 369, 486-488.
25. Scott, D.B., Blanpied, T.A. & Ehlers, M.D. (2003) Coordinated PKA and PKC phosphorylation suppresses RXR-mediated ER retention and regulates the surface delivery of NMDA receptors. Neuropharmacology, 45, 755-767.
26. Terry-Lorenzo, R.T., Roadcap, D.W., Otsuka, T., Blanpied, T.A., Zamorano, P.L., Garner, C.C., Shenolikar, S. & Ehlers, M.D. (2005) Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation. Mol. Biol. Cell., 16, 2349-2362.
27. Wang, J.H. & Stelzer, A. (1994) Inhibition of phosphatase 2B prevents expression of hippocampal long-term potentiation. Neuroreport, 5, 2377-2380.
28. Westphal, R.S., Tavalin, S.J., Lin, J.W., Alto, N.M., Fraser, I.D., Langeberg, L.K., Sheng, M. & Scott, J.D. (1999) Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex. Science, 285, 93-96.
29. Winder, D.G. & Sweatt, J.D. (2001) Roles of serine/threonine phosphatases in hippocampal synaptic plasticity. Nat. Rev. Neurosci., 2, 461-474.
30. Woo, N.H., Abel, T. & Nguyen, P.V. (2002) Genetic and pharmacological demonstration of a role for cyclic AMP-dependent protein kinase-mediated suppression of protein phosphatases in gating the expression of late LTP. Eur. J. Neurosci., 16, 1871-1876.