-
1
-
-
0742305866
-
Network biology: understanding the cell's functional organization
-
Barabasi A.L., Oltvai Z.N. Network biology: understanding the cell's functional organization. Nat Rev Genet 2004, 5:101-113.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
2
-
-
84861443800
-
Natural strategies for the spatial optimization of metabolism in synthetic biology
-
Agapakis C.M., Boyle P.M., Silver P.A. Natural strategies for the spatial optimization of metabolism in synthetic biology. Nat Chem Biol 2012, 8:527-535.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 527-535
-
-
Agapakis, C.M.1
Boyle, P.M.2
Silver, P.A.3
-
3
-
-
84871435690
-
Evolution of intracellular compartmentalization
-
Diekmann Y., Pereira-Leal J.B. Evolution of intracellular compartmentalization. Biochem J 2013, 449:319-331.
-
(2013)
Biochem J
, vol.449
, pp. 319-331
-
-
Diekmann, Y.1
Pereira-Leal, J.B.2
-
4
-
-
0023228466
-
Compartmentation of carbohydrate metabolism in vascular smooth muscle
-
Lynch R.M., Paul R.J. Compartmentation of carbohydrate metabolism in vascular smooth muscle. Am J Physiol 1987, 252:C328-C334.
-
(1987)
Am J Physiol
, vol.252
, pp. C328-C334
-
-
Lynch, R.M.1
Paul, R.J.2
-
5
-
-
0028913916
-
Microcompartmentation, metabolic channelling and carbohydrate metabolism
-
al-Habori M. Microcompartmentation, metabolic channelling and carbohydrate metabolism. Int J Biochem Cell Biol 1995, 27:123-132.
-
(1995)
Int J Biochem Cell Biol
, vol.27
, pp. 123-132
-
-
al-Habori, M.1
-
6
-
-
84881119066
-
Role of PFKFB3-driven glycolysis in vessel sprouting
-
De Bock K., Georgiadou M., Schoors S., Kuchnio A., Wong B.W., Cantelmo A.R., Quaegebeur A., Ghesquiere B., Cauwenberghs S., Eelen G., et al. Role of PFKFB3-driven glycolysis in vessel sprouting. Cell 2013, 154:651-663.
-
(2013)
Cell
, vol.154
, pp. 651-663
-
-
De Bock, K.1
Georgiadou, M.2
Schoors, S.3
Kuchnio, A.4
Wong, B.W.5
Cantelmo, A.R.6
Quaegebeur, A.7
Ghesquiere, B.8
Cauwenberghs, S.9
Eelen, G.10
-
7
-
-
0019321365
-
Compartmentation of glycolytic enzymes in nerve endings as determined by glutaraldehyde fixation
-
Knull H.R. Compartmentation of glycolytic enzymes in nerve endings as determined by glutaraldehyde fixation. J Biol Chem 1980, 255:6439-6444.
-
(1980)
J Biol Chem
, vol.255
, pp. 6439-6444
-
-
Knull, H.R.1
-
8
-
-
0031053616
-
Glyceraldehyde-3-phosphate dehydrogenase activity and F-actin associations in synaptosomes and postsynaptic densities of porcine cerebral cortex
-
Rogalski-Wilk A.A., Cohen R.S. Glyceraldehyde-3-phosphate dehydrogenase activity and F-actin associations in synaptosomes and postsynaptic densities of porcine cerebral cortex. Cell Mol Neurobiol 1997, 17:51-70.
-
(1997)
Cell Mol Neurobiol
, vol.17
, pp. 51-70
-
-
Rogalski-Wilk, A.A.1
Cohen, R.S.2
-
9
-
-
0030768060
-
Flight muscle function in Drosophila requires colocalization of glycolytic enzymes
-
Wojtas K., Slepecky N., von Kalm L., Sullivan D. Flight muscle function in Drosophila requires colocalization of glycolytic enzymes. Mol Biol Cell 1997, 8:1665-1675.
-
(1997)
Mol Biol Cell
, vol.8
, pp. 1665-1675
-
-
Wojtas, K.1
Slepecky, N.2
von Kalm, L.3
Sullivan, D.4
-
10
-
-
84870153086
-
Dynamic reorganization of metabolic enzymes into intracellular bodies
-
O'Connell J.D., Zhao A., Ellington A.D., Marcotte E.M. Dynamic reorganization of metabolic enzymes into intracellular bodies. Annu Rev Cell Dev Biol 2012, 28:89-111.
-
(2012)
Annu Rev Cell Dev Biol
, vol.28
, pp. 89-111
-
-
O'Connell, J.D.1
Zhao, A.2
Ellington, A.D.3
Marcotte, E.M.4
-
11
-
-
81355142010
-
Signaling pathways: purinosomes under GPCR control
-
Mohr K., Kostenis E. Signaling pathways: purinosomes under GPCR control. Nat Chem Biol 2011, 7:860-861.
-
(2011)
Nat Chem Biol
, vol.7
, pp. 860-861
-
-
Mohr, K.1
Kostenis, E.2
-
12
-
-
84876891366
-
The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans
-
Zhao H., French J.B., Fang Y., Benkovic S.J. The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans. Chem Commun (Camb) 2013, 49:4444-4452.
-
(2013)
Chem Commun (Camb)
, vol.49
, pp. 4444-4452
-
-
Zhao, H.1
French, J.B.2
Fang, Y.3
Benkovic, S.J.4
-
13
-
-
33751085376
-
The three-dimensional structure of an eukaryotic glutamine synthetase: functional implications of its oligomeric structure
-
Llorca O., Betti M., Gonzalez J.M., Valencia A., Marquez A.J., Valpuesta J.M. The three-dimensional structure of an eukaryotic glutamine synthetase: functional implications of its oligomeric structure. J Struct Biol 2006, 156:469-479.
-
(2006)
J Struct Biol
, vol.156
, pp. 469-479
-
-
Llorca, O.1
Betti, M.2
Gonzalez, J.M.3
Valencia, A.4
Marquez, A.J.5
Valpuesta, J.M.6
-
14
-
-
0035728325
-
Reversible binding of glycolytic enzymes and size change in the actin-containing filaments of the frog skeletal muscle
-
Fulgenzi G., Graciotti L., Corsi A., Granata A.L. Reversible binding of glycolytic enzymes and size change in the actin-containing filaments of the frog skeletal muscle. J Muscle Res Cell Motil 2001, 22:391-397.
-
(2001)
J Muscle Res Cell Motil
, vol.22
, pp. 391-397
-
-
Fulgenzi, G.1
Graciotti, L.2
Corsi, A.3
Granata, A.L.4
-
15
-
-
77951024214
-
Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes
-
Real-Hohn A., Zancan P., Da Silva D., Martins E.R., Salgado L.T., Mermelstein C.S., Gomes A.M., Sola-Penna M. Filamentous actin and its associated binding proteins are the stimulatory site for 6-phosphofructo-1-kinase association within the membrane of human erythrocytes. Biochimie 2010, 92:538-544.
-
(2010)
Biochimie
, vol.92
, pp. 538-544
-
-
Real-Hohn, A.1
Zancan, P.2
Da Silva, D.3
Martins, E.R.4
Salgado, L.T.5
Mermelstein, C.S.6
Gomes, A.M.7
Sola-Penna, M.8
-
16
-
-
84864748956
-
Fulfilling the metabolic requirements for cell proliferation
-
Moncada S., Higgs E.A., Colombo S.L. Fulfilling the metabolic requirements for cell proliferation. Biochem J 2012, 446:1-7.
-
(2012)
Biochem J
, vol.446
, pp. 1-7
-
-
Moncada, S.1
Higgs, E.A.2
Colombo, S.L.3
-
17
-
-
0025886135
-
Peroxisomal oxidases and catalase in liver and kidney homogenates of normal and di(ethylhexyl)phthalate-fed rats
-
Reubsaet F.A., Veerkamp J.H., Bruckwilder M.L., Trijbels J.M., Monnens L.A. Peroxisomal oxidases and catalase in liver and kidney homogenates of normal and di(ethylhexyl)phthalate-fed rats. Int J Biochem 1991, 23:961-967.
-
(1991)
Int J Biochem
, vol.23
, pp. 961-967
-
-
Reubsaet, F.A.1
Veerkamp, J.H.2
Bruckwilder, M.L.3
Trijbels, J.M.4
Monnens, L.A.5
-
18
-
-
0033792138
-
Peroxisomes in human fibroblasts have a basic pH
-
Dansen T.B., Wirtz K.W., Wanders R.J., Pap E.H. Peroxisomes in human fibroblasts have a basic pH. Nat Cell Biol 2000, 2:51-53.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 51-53
-
-
Dansen, T.B.1
Wirtz, K.W.2
Wanders, R.J.3
Pap, E.H.4
-
19
-
-
4944259643
-
The peroxisomal lumen in Saccharomyces cerevisiae is alkaline
-
van Roermund C.W., de Jong M.L.IJ., van Marle J., Dansen T.B., Wanders R.J., Waterham H.R. The peroxisomal lumen in Saccharomyces cerevisiae is alkaline. J Cell Sci 2004, 117:4231-4237.
-
(2004)
J Cell Sci
, vol.117
, pp. 4231-4237
-
-
van Roermund, C.W.1
de Jong, M.L.I.J.2
van Marle, J.3
Dansen, T.B.4
Wanders, R.J.5
Waterham, H.R.6
-
20
-
-
77954484645
-
Peroxisomes are oxidative organelles
-
Antonenkov V.D., Grunau S., Ohlmeier S., Hiltunen J.K. Peroxisomes are oxidative organelles. Antioxid Redox Signal 2010, 13:525-537.
-
(2010)
Antioxid Redox Signal
, vol.13
, pp. 525-537
-
-
Antonenkov, V.D.1
Grunau, S.2
Ohlmeier, S.3
Hiltunen, J.K.4
-
21
-
-
44649108365
-
Metabolic compartmentation-a system level property of muscle cells: real problems of diffusion in living cells
-
Saks V., Beraud N., Wallimann T. Metabolic compartmentation-a system level property of muscle cells: real problems of diffusion in living cells. Int J Mol Sci 2008, 9:751-767.
-
(2008)
Int J Mol Sci
, vol.9
, pp. 751-767
-
-
Saks, V.1
Beraud, N.2
Wallimann, T.3
-
22
-
-
27944487902
-
Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes
-
Tu B.P., Kudlicki A., Rowicka M., McKnight S.L. Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes. Science 2005, 310:1152-1158.
-
(2005)
Science
, vol.310
, pp. 1152-1158
-
-
Tu, B.P.1
Kudlicki, A.2
Rowicka, M.3
McKnight, S.L.4
-
23
-
-
84861851223
-
Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level
-
Obel L.F., Muller M.S., Walls A.B., Sickmann H.M., Bak L.K., Waagepetersen H.S., Schousboe A. Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level. Front Neuroenerg 2012, 4:3.
-
(2012)
Front Neuroenerg
, vol.4
, pp. 3
-
-
Obel, L.F.1
Muller, M.S.2
Walls, A.B.3
Sickmann, H.M.4
Bak, L.K.5
Waagepetersen, H.S.6
Schousboe, A.7
-
24
-
-
0022361519
-
Energy metabolism and transduction in smooth muscle
-
Lynch R.M., Paul R.J. Energy metabolism and transduction in smooth muscle. Experientia 1985, 41:970-977.
-
(1985)
Experientia
, vol.41
, pp. 970-977
-
-
Lynch, R.M.1
Paul, R.J.2
-
25
-
-
0016808875
-
Positional information and pattern regulation in hydra: enzyme profiles
-
Baquer N.Z., McLean P., Hornbruch A., Wolpert L. Positional information and pattern regulation in hydra: enzyme profiles. J Embryol Exp Morphol 1975, 33:853-867.
-
(1975)
J Embryol Exp Morphol
, vol.33
, pp. 853-867
-
-
Baquer, N.Z.1
McLean, P.2
Hornbruch, A.3
Wolpert, L.4
-
26
-
-
81055132901
-
Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa
-
Hereng T.H., Elgstoen K.B., Cederkvist F.H., Eide L., Jahnsen T., Skalhegg B.S., Rosendal K.R. Exogenous pyruvate accelerates glycolysis and promotes capacitation in human spermatozoa. Hum Reprod 2011, 26:3249-3263.
-
(2011)
Hum Reprod
, vol.26
, pp. 3249-3263
-
-
Hereng, T.H.1
Elgstoen, K.B.2
Cederkvist, F.H.3
Eide, L.4
Jahnsen, T.5
Skalhegg, B.S.6
Rosendal, K.R.7
-
27
-
-
42049092972
-
Regulation of actin assembly associated with protrusion and adhesion in cell migration
-
Le Clainche C., Carlier M.F. Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev 2008, 88:489-513.
-
(2008)
Physiol Rev
, vol.88
, pp. 489-513
-
-
Le Clainche, C.1
Carlier, M.F.2
-
28
-
-
59449083634
-
Modulation of cell motility by spatial repositioning of enzymatic ATP/ADP exchange capacity
-
van Horssen R., Janssen E., Peters W., van de Pasch L., Lindert M.M., van Dommelen M.M., Linssen P.C., Hagen T.L., Fransen J.A., Wieringa B. Modulation of cell motility by spatial repositioning of enzymatic ATP/ADP exchange capacity. J Biol Chem 2009, 284:1620-1627.
-
(2009)
J Biol Chem
, vol.284
, pp. 1620-1627
-
-
van Horssen, R.1
Janssen, E.2
Peters, W.3
van de Pasch, L.4
Lindert, M.M.5
van Dommelen, M.M.6
Linssen, P.C.7
Hagen, T.L.8
Fransen, J.A.9
Wieringa, B.10
-
29
-
-
84922060844
-
Mechanisms of endothelial cell migration
-
Michaelis U.R. Mechanisms of endothelial cell migration. Cell Mol Life Sci 2014, 71(21):4131-4148.
-
(2014)
Cell Mol Life Sci
, vol.71
, Issue.21
, pp. 4131-4148
-
-
Michaelis, U.R.1
-
30
-
-
84922581123
-
Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis
-
Leong H.S., Robertson A.E., Stoletov K., Leith S.J., Chin C.A., Chien A.E., Hague M.N., Ablack A., Carmine-Simmen K., McPherson V.A., et al. Invadopodia are required for cancer cell extravasation and are a therapeutic target for metastasis. Cell Rep 2014, 8:1558-1570.
-
(2014)
Cell Rep
, vol.8
, pp. 1558-1570
-
-
Leong, H.S.1
Robertson, A.E.2
Stoletov, K.3
Leith, S.J.4
Chin, C.A.5
Chien, A.E.6
Hague, M.N.7
Ablack, A.8
Carmine-Simmen, K.9
McPherson, V.A.10
-
31
-
-
79151480835
-
Novel invadopodia components revealed by differential proteomic analysis
-
Attanasio F., Caldieri G., Giacchetti G., van Horssen R., Wieringa B., Buccione R. Novel invadopodia components revealed by differential proteomic analysis. Eur J Cell Biol 2011, 90:115-127.
-
(2011)
Eur J Cell Biol
, vol.90
, pp. 115-127
-
-
Attanasio, F.1
Caldieri, G.2
Giacchetti, G.3
van Horssen, R.4
Wieringa, B.5
Buccione, R.6
-
32
-
-
84875379535
-
Cancer cell metabolism regulates extracellular matrix degradation by invadopodia
-
van Horssen R., Buccione R., Willemse M., Cingir S., Wieringa B., Attanasio F. Cancer cell metabolism regulates extracellular matrix degradation by invadopodia. Eur J Cell Biol 2013, 92:113-121.
-
(2013)
Eur J Cell Biol
, vol.92
, pp. 113-121
-
-
van Horssen, R.1
Buccione, R.2
Willemse, M.3
Cingir, S.4
Wieringa, B.5
Attanasio, F.6
-
33
-
-
84870784470
-
Mitochondrial network in glioma's invadopodia displays an activated state both in situ and in vitro: potential functional implications
-
Arismendi-Morillo G., Hoa N.T., Ge L., Jadus M.R. Mitochondrial network in glioma's invadopodia displays an activated state both in situ and in vitro: potential functional implications. Ultrastruct Pathol 2012, 36:409-414.
-
(2012)
Ultrastruct Pathol
, vol.36
, pp. 409-414
-
-
Arismendi-Morillo, G.1
Hoa, N.T.2
Ge, L.3
Jadus, M.R.4
-
34
-
-
84877290780
-
Mitochondrial localization and the persistent migration of epithelial cancer cells
-
Desai S.P., Bhatia S.N., Toner M., Irimia D. Mitochondrial localization and the persistent migration of epithelial cancer cells. Biophys J 2013, 104:2077-2088.
-
(2013)
Biophys J
, vol.104
, pp. 2077-2088
-
-
Desai, S.P.1
Bhatia, S.N.2
Toner, M.3
Irimia, D.4
-
35
-
-
84885181954
-
Mitochondrial dynamics regulates migration and invasion of breast cancer cells
-
Zhao J., Zhang J., Yu M., Xie Y., Huang Y., Wolff D.W., Abel P.W., Tu Y. Mitochondrial dynamics regulates migration and invasion of breast cancer cells. Oncogene 2013, 32:4814-4824.
-
(2013)
Oncogene
, vol.32
, pp. 4814-4824
-
-
Zhao, J.1
Zhang, J.2
Yu, M.3
Xie, Y.4
Huang, Y.5
Wolff, D.W.6
Abel, P.W.7
Tu, Y.8
-
36
-
-
67349256860
-
Bringing up the rear: defining the roles of the uropod
-
Sanchez-Madrid F., Serrador J.M. Bringing up the rear: defining the roles of the uropod. Nat Rev Mol Cell Biol 2009, 10:353-359.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 353-359
-
-
Sanchez-Madrid, F.1
Serrador, J.M.2
-
37
-
-
84896539284
-
Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity
-
Morlino G., Barreiro O., Baixauli F., Robles-Valero J., Gonzalez-Granado J.M., Villa-Bellosta R., Cuenca J., Sanchez-Sorzano C.O., Veiga E., Martin-Cofreces N.B., et al. Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity. Mol Cell Biol 2014, 34:1412-1426.
-
(2014)
Mol Cell Biol
, vol.34
, pp. 1412-1426
-
-
Morlino, G.1
Barreiro, O.2
Baixauli, F.3
Robles-Valero, J.4
Gonzalez-Granado, J.M.5
Villa-Bellosta, R.6
Cuenca, J.7
Sanchez-Sorzano, C.O.8
Veiga, E.9
Martin-Cofreces, N.B.10
-
38
-
-
33845908501
-
Orchestration of lymphocyte chemotaxis by mitochondrial dynamics
-
Campello S., Lacalle R.A., Bettella M., Manes S., Scorrano L., Viola A. Orchestration of lymphocyte chemotaxis by mitochondrial dynamics. J Exp Med 2006, 203:2879-2886.
-
(2006)
J Exp Med
, vol.203
, pp. 2879-2886
-
-
Campello, S.1
Lacalle, R.A.2
Bettella, M.3
Manes, S.4
Scorrano, L.5
Viola, A.6
-
39
-
-
84856056846
-
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration
-
Sheng Z.H., Cai Q. Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci 2012, 13:77-93.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 77-93
-
-
Sheng, Z.H.1
Cai, Q.2
-
40
-
-
84871982184
-
Synaptic vesicle exocytosis in hippocampal synaptosomes correlates directly with total mitochondrial volume
-
Ivannikov M.V., Sugimori M., Llinas R.R. Synaptic vesicle exocytosis in hippocampal synaptosomes correlates directly with total mitochondrial volume. J Mol Neurosci 2013, 49:223-230.
-
(2013)
J Mol Neurosci
, vol.49
, pp. 223-230
-
-
Ivannikov, M.V.1
Sugimori, M.2
Llinas, R.R.3
-
41
-
-
84890982921
-
Mitochondria coordinate sites of axon branching through localized intra-axonal protein synthesis
-
Spillane M., Ketschek A., Merianda T.T., Twiss J.L., Gallo G. Mitochondria coordinate sites of axon branching through localized intra-axonal protein synthesis. Cell Rep 2013, 5:1564-1575.
-
(2013)
Cell Rep
, vol.5
, pp. 1564-1575
-
-
Spillane, M.1
Ketschek, A.2
Merianda, T.T.3
Twiss, J.L.4
Gallo, G.5
-
42
-
-
84873323723
-
Vesicular glycolysis provides on-board energy for fast axonal transport
-
Zala D., Hinckelmann M.V., Yu H., Lyra da Cunha M.M., Liot G., Cordelieres F.P., Marco S., Saudou F. Vesicular glycolysis provides on-board energy for fast axonal transport. Cell 2013, 152:479-491.
-
(2013)
Cell
, vol.152
, pp. 479-491
-
-
Zala, D.1
Hinckelmann, M.V.2
Yu, H.3
Lyra da Cunha, M.M.4
Liot, G.5
Cordelieres, F.P.6
Marco, S.7
Saudou, F.8
-
43
-
-
77953912359
-
Calcium clearance and its energy requirements in cerebellar neurons
-
Ivannikov M.V., Sugimori M., Llinas R.R. Calcium clearance and its energy requirements in cerebellar neurons. Cell Calcium 2010, 47:507-513.
-
(2010)
Cell Calcium
, vol.47
, pp. 507-513
-
-
Ivannikov, M.V.1
Sugimori, M.2
Llinas, R.R.3
-
44
-
-
0030693787
-
The synthesis of ATP by glycolytic enzymes in the postsynaptic density and the effect of endogenously generated nitric oxide
-
Wu K., Aoki C., Elste A., Rogalski-Wilk A.A., Siekevitz P. The synthesis of ATP by glycolytic enzymes in the postsynaptic density and the effect of endogenously generated nitric oxide. Proc Natl Acad Sci U S A 1997, 94:13273-13278.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13273-13278
-
-
Wu, K.1
Aoki, C.2
Elste, A.3
Rogalski-Wilk, A.A.4
Siekevitz, P.5
-
45
-
-
33846423878
-
Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis
-
Hertz L., Peng L., Dienel G.A. Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis. J Cereb Blood Flow Metab 2007, 27:219-249.
-
(2007)
J Cereb Blood Flow Metab
, vol.27
, pp. 219-249
-
-
Hertz, L.1
Peng, L.2
Dienel, G.A.3
-
46
-
-
82955168362
-
Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation
-
Belanger M., Allaman I., Magistretti P.J. Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab 2011, 14:724-738.
-
(2011)
Cell Metab
, vol.14
, pp. 724-738
-
-
Belanger, M.1
Allaman, I.2
Magistretti, P.J.3
-
47
-
-
79955960768
-
Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes
-
Cai L., Sutter B.M., Li B., Tu B.P. Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. Mol Cell 2011, 42:426-437.
-
(2011)
Mol Cell
, vol.42
, pp. 426-437
-
-
Cai, L.1
Sutter, B.M.2
Li, B.3
Tu, B.P.4
-
48
-
-
66249105703
-
ATP-citrate lyase links cellular metabolism to histone acetylation
-
Wellen K.E., Hatzivassiliou G., Sachdeva U.M., Bui T.V., Cross J.R., Thompson C.B. ATP-citrate lyase links cellular metabolism to histone acetylation. Science 2009, 324:1076-1080.
-
(2009)
Science
, vol.324
, pp. 1076-1080
-
-
Wellen, K.E.1
Hatzivassiliou, G.2
Sachdeva, U.M.3
Bui, T.V.4
Cross, J.R.5
Thompson, C.B.6
-
49
-
-
26644441651
-
ATP citrate lyase inhibition can suppress tumor cell growth
-
Hatzivassiliou G., Zhao F., Bauer D.E., Andreadis C., Shaw A.N., Dhanak D., Hingorani S.R., Tuveson D.A., Thompson C.B. ATP citrate lyase inhibition can suppress tumor cell growth. Cancer Cell 2005, 8:311-321.
-
(2005)
Cancer Cell
, vol.8
, pp. 311-321
-
-
Hatzivassiliou, G.1
Zhao, F.2
Bauer, D.E.3
Andreadis, C.4
Shaw, A.N.5
Dhanak, D.6
Hingorani, S.R.7
Tuveson, D.A.8
Thompson, C.B.9
-
50
-
-
84905816638
-
Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation
-
Lee J.V., Carrer A., Shah S., Snyder N.W., Wei S., Venneti S., Worth A.J., Yuan Z.F., Lim H.W., Liu S., et al. Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation. Cell Metab 2014, 20(2):306-319.
-
(2014)
Cell Metab
, vol.20
, Issue.2
, pp. 306-319
-
-
Lee, J.V.1
Carrer, A.2
Shah, S.3
Snyder, N.W.4
Wei, S.5
Venneti, S.6
Worth, A.J.7
Yuan, Z.F.8
Lim, H.W.9
Liu, S.10
-
51
-
-
84895755121
-
Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan
-
Eisenberg T., Schroeder S., Andryushkova A., Pendl T., Kuttner V., Bhukel A., Marino G., Pietrocola F., Harger A., Zimmermann A., et al. Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan. Cell Metab 2014, 19:431-444.
-
(2014)
Cell Metab
, vol.19
, pp. 431-444
-
-
Eisenberg, T.1
Schroeder, S.2
Andryushkova, A.3
Pendl, T.4
Kuttner, V.5
Bhukel, A.6
Marino, G.7
Pietrocola, F.8
Harger, A.9
Zimmermann, A.10
-
52
-
-
9244245733
-
Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain
-
Hoshi M., Takashima A., Noguchi K., Murayama M., Sato M., Kondo S., Saitoh Y., Ishiguro K., Hoshino T., Imahori K. Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain. Proc Natl Acad Sci U S A 1996, 93:2719-2723.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 2719-2723
-
-
Hoshi, M.1
Takashima, A.2
Noguchi, K.3
Murayama, M.4
Sato, M.5
Kondo, S.6
Saitoh, Y.7
Ishiguro, K.8
Hoshino, T.9
Imahori, K.10
-
53
-
-
0029351956
-
Subcellular localization of pyruvate dehydrogenase dihydrolipoamide acetyltransferase in human intrahepatic biliary epithelial cells
-
Joplin R., Wallace L.L., Johnson G.D., Lindsay J.G., Yeaman S.J., Palmer J.M., Strain A.J., Neuberger J.M. Subcellular localization of pyruvate dehydrogenase dihydrolipoamide acetyltransferase in human intrahepatic biliary epithelial cells. J Pathol 1995, 176:381-390.
-
(1995)
J Pathol
, vol.176
, pp. 381-390
-
-
Joplin, R.1
Wallace, L.L.2
Johnson, G.D.3
Lindsay, J.G.4
Yeaman, S.J.5
Palmer, J.M.6
Strain, A.J.7
Neuberger, J.M.8
-
54
-
-
84903954689
-
A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation
-
Sutendra G., Kinnaird A., Dromparis P., Paulin R., Stenson T.H., Haromy A., Hashimoto K., Zhang N., Flaim E., Michelakis E.D. A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation. Cell 2014, 158:84-97.
-
(2014)
Cell
, vol.158
, pp. 84-97
-
-
Sutendra, G.1
Kinnaird, A.2
Dromparis, P.3
Paulin, R.4
Stenson, T.H.5
Haromy, A.6
Hashimoto, K.7
Zhang, N.8
Flaim, E.9
Michelakis, E.D.10
-
55
-
-
84862776933
-
Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase
-
Gao X., Wang H., Yang J.J., Liu X., Liu Z.R. Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase. Mol Cell 2012, 45:598-609.
-
(2012)
Mol Cell
, vol.45
, pp. 598-609
-
-
Gao, X.1
Wang, H.2
Yang, J.J.3
Liu, X.4
Liu, Z.R.5
-
56
-
-
79957567239
-
Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1
-
Luo W., Hu H., Chang R., Zhong J., Knabel M., O'Meally R., Cole R.N., Pandey A., Semenza G.L. Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell 2011, 145:732-744.
-
(2011)
Cell
, vol.145
, pp. 732-744
-
-
Luo, W.1
Hu, H.2
Chang, R.3
Zhong, J.4
Knabel, M.5
O'Meally, R.6
Cole, R.N.7
Pandey, A.8
Semenza, G.L.9
-
57
-
-
82555170271
-
Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation
-
Yang W., Xia Y., Ji H., Zheng Y., Liang J., Huang W., Gao X., Aldape K., Lu Z. Nuclear PKM2 regulates beta-catenin transactivation upon EGFR activation. Nature 2011, 480:118-122.
-
(2011)
Nature
, vol.480
, pp. 118-122
-
-
Yang, W.1
Xia, Y.2
Ji, H.3
Zheng, Y.4
Liang, J.5
Huang, W.6
Gao, X.7
Aldape, K.8
Lu, Z.9
-
58
-
-
84870598190
-
ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
-
Yang W., Zheng Y., Xia Y., Ji H., Chen X., Guo F., Lyssiotis C.A., Aldape K., Cantley L.C., Lu Z. ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. Nat Cell Biol 2012, 14:1295-1304.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1295-1304
-
-
Yang, W.1
Zheng, Y.2
Xia, Y.3
Ji, H.4
Chen, X.5
Guo, F.6
Lyssiotis, C.A.7
Aldape, K.8
Cantley, L.C.9
Lu, Z.10
-
59
-
-
84887206685
-
Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization
-
Lv L., Xu Y.P., Zhao D., Li F.L., Wang W., Sasaki N., Jiang Y., Zhou X., Li T.T., Guan K.L., et al. Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization. Mol Cell 2013, 52:340-352.
-
(2013)
Mol Cell
, vol.52
, pp. 340-352
-
-
Lv, L.1
Xu, Y.P.2
Zhao, D.3
Li, F.L.4
Wang, W.5
Sasaki, N.6
Jiang, Y.7
Zhou, X.8
Li, T.T.9
Guan, K.L.10
-
60
-
-
84904489275
-
PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis
-
Yang L., Xie M., Yang M., Yu Y., Zhu S., Hou W., Kang R., Lotze M.T., Billiar T.R., Wang H., et al. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis. Nat Commun 2014, 5:4436.
-
(2014)
Nat Commun
, vol.5
, pp. 4436
-
-
Yang, L.1
Xie, M.2
Yang, M.3
Yu, Y.4
Zhu, S.5
Hou, W.6
Kang, R.7
Lotze, M.T.8
Billiar, T.R.9
Wang, H.10
-
61
-
-
78649842470
-
The diverse functions of GAPDH: views from different subcellular compartments
-
Tristan C., Shahani N., Sedlak T.W., Sawa A. The diverse functions of GAPDH: views from different subcellular compartments. Cell Signal 2011, 23:317-323.
-
(2011)
Cell Signal
, vol.23
, pp. 317-323
-
-
Tristan, C.1
Shahani, N.2
Sedlak, T.W.3
Sawa, A.4
-
62
-
-
84878831880
-
Posttranscriptional control of T cell effector function by aerobic glycolysis
-
Chang C.H., Curtis J.D., Maggi L.B., Faubert B., Villarino A.V., O'Sullivan D., Huang S.C., van der Windt G.J., Blagih J., Qiu J., et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 2013, 153:1239-1251.
-
(2013)
Cell
, vol.153
, pp. 1239-1251
-
-
Chang, C.H.1
Curtis, J.D.2
Maggi, L.B.3
Faubert, B.4
Villarino, A.V.5
O'Sullivan, D.6
Huang, S.C.7
van der Windt, G.J.8
Blagih, J.9
Qiu, J.10
-
63
-
-
84863621527
-
Cancer epigenetics: from mechanism to therapy
-
Dawson M.A., Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell 2012, 150:12-27.
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
65
-
-
80054046029
-
Aerobic glycolysis: meeting the metabolic requirements of cell proliferation
-
Lunt S.Y., Vander Heiden M.G. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. Annu Rev Cell Dev Biol 2011, 27:441-464.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 441-464
-
-
Lunt, S.Y.1
Vander Heiden, M.G.2
-
66
-
-
84891841003
-
Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis
-
Schoors S., De Bock K., Cantelmo A.R., Georgiadou M., Ghesquiere B., Cauwenberghs S., Kuchnio A., Wong B.W., Quaegebeur A., Goveia J., et al. Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis. Cell Metab 2014, 19:37-48.
-
(2014)
Cell Metab
, vol.19
, pp. 37-48
-
-
Schoors, S.1
De Bock, K.2
Cantelmo, A.R.3
Georgiadou, M.4
Ghesquiere, B.5
Cauwenberghs, S.6
Kuchnio, A.7
Wong, B.W.8
Quaegebeur, A.9
Goveia, J.10
-
67
-
-
0017153683
-
Aerobic glycolysis during lymphocyte proliferation
-
Wang T., Marquardt C., Foker J. Aerobic glycolysis during lymphocyte proliferation. Nature 1976, 261:702-705.
-
(1976)
Nature
, vol.261
, pp. 702-705
-
-
Wang, T.1
Marquardt, C.2
Foker, J.3
-
68
-
-
76249114497
-
E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation
-
Almeida A., Bolanos J.P., Moncada S. E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation. Proc Natl Acad Sci U S A 2010, 107:738-741.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 738-741
-
-
Almeida, A.1
Bolanos, J.P.2
Moncada, S.3
-
69
-
-
84855476912
-
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells
-
Colombo S.L., Palacios-Callender M., Frakich N., Carcamo S., Kovacs I., Tudzarova S., Moncada S. Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells. Proc Natl Acad Sci U S A 2011, 108:21069-21074.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 21069-21074
-
-
Colombo, S.L.1
Palacios-Callender, M.2
Frakich, N.3
Carcamo, S.4
Kovacs, I.5
Tudzarova, S.6
Moncada, S.7
-
70
-
-
78650491025
-
Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes
-
Colombo S.L., Palacios-Callender M., Frakich N., De Leon J., Schmitt C.A., Boorn L., Davis N., Moncada S. Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes. Proc Natl Acad Sci U S A 2010, 107:18868-18873.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18868-18873
-
-
Colombo, S.L.1
Palacios-Callender, M.2
Frakich, N.3
De Leon, J.4
Schmitt, C.A.5
Boorn, L.6
Davis, N.7
Moncada, S.8
-
71
-
-
79955076736
-
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle
-
Tudzarova S., Colombo S.L., Stoeber K., Carcamo S., Williams G.H., Moncada S. Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-beta-TrCP, sequentially regulate glycolysis during the cell cycle. Proc Natl Acad Sci U S A 2011, 108:5278-5283.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 5278-5283
-
-
Tudzarova, S.1
Colombo, S.L.2
Stoeber, K.3
Carcamo, S.4
Williams, G.H.5
Moncada, S.6
-
72
-
-
65649120706
-
Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29
-
Vizan P., Alcarraz-Vizan G., Diaz-Moralli S., Solovjeva O.N., Frederiks W.M., Cascante M. Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29. Int J Cancer 2009, 124:2789-2796.
-
(2009)
Int J Cancer
, vol.124
, pp. 2789-2796
-
-
Vizan, P.1
Alcarraz-Vizan, G.2
Diaz-Moralli, S.3
Solovjeva, O.N.4
Frederiks, W.M.5
Cascante, M.6
-
73
-
-
84881453767
-
TAp73 enhances the pentose phosphate pathway and supports cell proliferation
-
Du W., Jiang P., Mancuso A., Stonestrom A., Brewer M.D., Minn A.J., Mak T.W., Wu M., Yang X. TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nat Cell Biol 2013, 15:991-1000.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 991-1000
-
-
Du, W.1
Jiang, P.2
Mancuso, A.3
Stonestrom, A.4
Brewer, M.D.5
Minn, A.J.6
Mak, T.W.7
Wu, M.8
Yang, X.9
-
74
-
-
0016741871
-
Rapid increase of phosphoribosyl pyrophosphate concentration after mitogenic stimulation of lymphocytes
-
Hovi T., Allison A.C., Allsop J. Rapid increase of phosphoribosyl pyrophosphate concentration after mitogenic stimulation of lymphocytes. FEBS Lett 1975, 55:291-293.
-
(1975)
FEBS Lett
, vol.55
, pp. 291-293
-
-
Hovi, T.1
Allison, A.C.2
Allsop, J.3
-
75
-
-
0034002793
-
Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
-
Kuhajda F.P. Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology. Nutrition 2000, 16:202-208.
-
(2000)
Nutrition
, vol.16
, pp. 202-208
-
-
Kuhajda, F.P.1
-
76
-
-
33845909566
-
Pharmacological inhibitors of Fatty Acid Synthase (FASN)-catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?
-
Lupu R., Menendez J.A. Pharmacological inhibitors of Fatty Acid Synthase (FASN)-catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?. Curr Pharm Biotechnol 2006, 7:483-493.
-
(2006)
Curr Pharm Biotechnol
, vol.7
, pp. 483-493
-
-
Lupu, R.1
Menendez, J.A.2
-
77
-
-
84902332213
-
Quantitative flux analysis reveals folate-dependent NADPH production
-
Fan J., Ye J., Kamphorst J.J., Shlomi T., Thompson C.B., Rabinowitz J.D. Quantitative flux analysis reveals folate-dependent NADPH production. Nature 2014, 510:298-302.
-
(2014)
Nature
, vol.510
, pp. 298-302
-
-
Fan, J.1
Ye, J.2
Kamphorst, J.J.3
Shlomi, T.4
Thompson, C.B.5
Rabinowitz, J.D.6
-
78
-
-
84904504373
-
Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells
-
Lewis C.A., Parker S.J., Fiske B.P., McCloskey D., Gui D.Y., Green C.R., Vokes N.I., Feist A.M., Vander Heiden M.G., Metallo C.M. Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells. Mol Cell 2014, 55:253-263.
-
(2014)
Mol Cell
, vol.55
, pp. 253-263
-
-
Lewis, C.A.1
Parker, S.J.2
Fiske, B.P.3
McCloskey, D.4
Gui, D.Y.5
Green, C.R.6
Vokes, N.I.7
Feist, A.M.8
Vander Heiden, M.G.9
Metallo, C.M.10
-
79
-
-
84901263663
-
Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells
-
Labuschagne C.F., van den Broek N.J., Mackay G.M., Vousden K.H., Maddocks O.D. Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells. Cell Rep 2014, 7:1248-1258.
-
(2014)
Cell Rep
, vol.7
, pp. 1248-1258
-
-
Labuschagne, C.F.1
van den Broek, N.J.2
Mackay, G.M.3
Vousden, K.H.4
Maddocks, O.D.5
-
80
-
-
84892599925
-
Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?
-
Schoors S., Cantelmo A.R., Georgiadou M., Stapor P., Wang X., Quaegebeur A., Cauwenberghs S., Wong B.W., Bifari F., Decimo I., et al. Incomplete and transitory decrease of glycolysis: a new paradigm for anti-angiogenic therapy?. Cell Cycle 2014, 13:16-22.
-
(2014)
Cell Cycle
, vol.13
, pp. 16-22
-
-
Schoors, S.1
Cantelmo, A.R.2
Georgiadou, M.3
Stapor, P.4
Wang, X.5
Quaegebeur, A.6
Cauwenberghs, S.7
Wong, B.W.8
Bifari, F.9
Decimo, I.10
-
81
-
-
76049084604
-
Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate
-
Dhar S., Lippard S.J. Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate. Proc Natl Acad Sci U S A 2009, 106:22199-22204.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 22199-22204
-
-
Dhar, S.1
Lippard, S.J.2
-
82
-
-
1942438684
-
Polymeric anticancer drugs with pH-controlled activation
-
Ulbrich K., Subr V. Polymeric anticancer drugs with pH-controlled activation. Adv Drug Deliv Rev 2004, 56:1023-1050.
-
(2004)
Adv Drug Deliv Rev
, vol.56
, pp. 1023-1050
-
-
Ulbrich, K.1
Subr, V.2
-
83
-
-
84900872269
-
Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate
-
Pathak R.K., Marrache S., Harn D.A., Dhar S. Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate. ACS Chem Biol 2014, 9:1178-1187.
-
(2014)
ACS Chem Biol
, vol.9
, pp. 1178-1187
-
-
Pathak, R.K.1
Marrache, S.2
Harn, D.A.3
Dhar, S.4
-
84
-
-
84916612839
-
Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells
-
In Press
-
Shiraishi T., Verdone J.E., Huang J., Kahlert U.D., Hernandez J.R., Torga G., Zarif J.C., Epstein T., Gatenby R., McCartney A., et al. Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells. Oncotarget 2014, In Press.
-
(2014)
Oncotarget
-
-
Shiraishi, T.1
Verdone, J.E.2
Huang, J.3
Kahlert, U.D.4
Hernandez, J.R.5
Torga, G.6
Zarif, J.C.7
Epstein, T.8
Gatenby, R.9
McCartney, A.10
|