Neuronal and astrocyte dysfunction diverges from embryonic fibroblasts in the Ndufs4fky/fky mouse

Bioscience Reports

Volumn 34, Issue 6, 2014, Pages

  Bird, Matthew J ^a,b   Wijeyeratne, Xiaonan W ^c   Komen, Jasper C ^a   Laskowski, Adrienne ^a   Ryan, Michael T ^c   Thorburn, David R ^a,b   Frazier, Ann E ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

Author keywords

Metabolic stress; Mitochondrial disease; Mouse models; Neuropathology; Primary cells; Reactive oxygen species

Indexed keywords

ADENOSINE TRIPHOSPHATE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); GALACTOSE; HYDROGEN PEROXIDE; NDUFS4 PROTEIN, MOUSE; ROTENONE; SUCCINATE DEHYDROGENASE (UBIQUINONE); SUCCINIC ACID DERIVATIVE; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DEATH; CELL FUNCTION; CELL PROTECTION; CELL STRUCTURE; CONTROLLED STUDY; ELECTRON TRANSPORT; EMBRYO; ENZYME SYNTHESIS; FIBROBLAST; LEIGH DISEASE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NERVE CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN FUNCTION; ANIMAL; ANIMAL EMBRYO; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DEFICIENCY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MITOCHONDRION; NECROSIS; PHYSIOLOGY; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CELLS, CULTURED; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; EMBRYO, MAMMALIAN; FIBROBLASTS; GALACTOSE; HYDROGEN PEROXIDE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED BALB C; MICE, KNOCKOUT; MITOCHONDRIA; NECROSIS; NEURONS; REACTIVE OXYGEN SPECIES; ROTENONE; SUCCINATES; SUPEROXIDES;

EID: 84915803260     PISSN: 01448463     EISSN: 15734935     Source Type: Journal    
DOI: 10.1042/BSR20140151     Document Type: Article

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