Altered trafficking and stability of polycystins underlie polycystic kidney disease

Journal of Clinical Investigation

Volumn 124, Issue 12, 2014, Pages 5129-5144

  Cai, Yiqiang ^a   Fedeles, Sorin V ^a   Dong, Ke ^a   Anyatonwu, Georgia ^a   Onoe, Tamehito ^a   Mitobe, Michihiro ^a   Gao, Jian Dong ^a   Okuhara, Dayne ^a   Tian, Xin ^a   Gallagher, Anna Rachel ^a   Tang, Zhangui ^a   Xie, Xiaoli ^a   Lalioti, Maria D ^a   Lee, Ann Hwee ^b   Ehrlich, Barbara E ^a   Somlo, Stefan ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; G PROTEIN COUPLED RECEPTOR; POLYCYSTIN 1; POLYCYSTIN 2; POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIC KIDNEY DISEASE 2 PROTEIN; POLYCYSTIN;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL CHROMOSOME; BIOTINYLATION; CELL SURFACE; CONTROLLED STUDY; GENE DOSAGE; GENETIC CODE; GLYCOSYLATION; KIDNEY POLYCYSTIC DISEASE; LIPID BILAYER; MISSENSE MUTATION; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT; STEADY STATE; ANIMAL; CELL LINE; EUKARYOTIC FLAGELLUM; GENETICS; HUMAN; METABOLISM; PATHOLOGY; POLYCYSTIC KIDNEY DISEASES; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

ANIMALS; CELL LINE; CILIA; HUMANS; MICE; MICE, TRANSGENIC; MUTATION, MISSENSE; POLYCYSTIC KIDNEY DISEASES; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; TRPP CATION CHANNELS;

EID: 84915775893     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI67273     Document Type: Article

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