Structural and molecular basis of the assembly of the TRPP2/PKD1 complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 28, 2009, Pages 11558-11563

  Yu, Yong ^a   Ulbrich, Maximilian H ^b   Li, Ming Hui ^a   Buraei, Zafir ^a   Chen, Xing Zhen ^d   Ong, Albert C M ^e   Tong, Liang ^a   Isacoff, Ehud Y ^b,c   Yang, Jian ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF ALBERTA   (Canada)

^e UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Autosomal dominant polycystic kidney disease; Single molecule imaging; Stoichiometry; Transient receptor potential channel; X ray crystallography

Indexed keywords

POLYCYSTIN 1; POLYCYSTIN 2; PROTEIN SUBUNIT;

ARTICLE; AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE CONTROL; GENE DISRUPTION; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; KIDNEY POLYCYSTIC DISEASE; MOLECULAR MECHANICS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; STOICHIOMETRY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CRYSTALLIZATION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, DNA; TRPP CATION CHANNELS; XENOPUS;

EID: 67650860463     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903684106     Document Type: Article

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