Synergistic activity of curcumin with methotrexate in ameliorating Freund's Complete Adjuvant induced arthritis with reduced hepatotoxicity in experimental animals

European Journal of Pharmacology

Volumn 668, Issue 1-2, 2011, Pages 293-298

  Banji, David ^a   Pinnapureddy, Jyothi ^a   Banji, Otilia J F ^a   Saidulu, A ^a   Hayath, Md Sikinder ^b  

^a Nalanda College of Pharmacy   (India)

^b Kamineni Institute of Medical Sciences   (India)

Author keywords

Curcumin; Freund's Complete Adjuvant; Hepatotoxicity; Methotreaxate; Oxidative

Indexed keywords

ALKALINE PHOSPHATASE; AMINOTRANSFERASE; CURCUMIN; LIPID PEROXIDE; METHOTREXATE;

ADJUVANT ARTHRITIS; ALKALINE PHOSPHATASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; DRUG POTENTIATION; FEMALE; HYPERBILIRUBINEMIA; LIVER PROTECTION; LIVER TOXICITY; LOW DRUG DOSE; MONOTHERAPY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RHEUMATOID ARTHRITIS;

ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ANIMALS; ARTHRITIS, EXPERIMENTAL; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; CURCUMIN; CYTOPROTECTION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FEMALE; FREUND'S ADJUVANT; LIPID PEROXIDATION; LIVER; METHOTREXATE; ORGAN SIZE; RATS; RATS, WISTAR;

EID: 80052076279     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.06.006     Document Type: Article

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