Gene expression profile in liver of differing ages of rats after single oral administration of acetaminophen

Journal of Toxicological Sciences

Volumn 31, Issue 5, 2006, Pages 491-507

  Morishita, Katsumi ^a   Mizukawa, Yumiko ^b   Kasahara, Toshihiko ^a   Okuyama, Manabu ^a   Takashima, Kayoko ^a   Toritsuka, Naoki ^a   Miyagishima, Toshikazu ^a   Nagao, Taku ^c   Urushidani, Tetsuro ^a,b  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Acetaminophen; Age related difference; Hepatotoxicity; Rat; Toxicogenomics

Indexed keywords

16ALPHA CYANOPREGNENOLONE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CAFFEINE; CARBON TETRACHLORIDE; CYTOCHROME P450 3A; CYTOCHROME P450 3A13; DEXAMETHASONE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE YC2; ISONIAZID; LACTATE DEHYDROGENASE; PARACETAMOL; TROGLITAZONE; UNCLASSIFIED DRUG;

AGE DISTRIBUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DETOXIFICATION; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; DRUG METABOLISM; DRUG SENSITIVITY; ENZYME ANALYSIS; ENZYME BLOOD LEVEL; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE INTERACTION; GENETIC ANALYSIS; HISTOPATHOLOGY; LIVER TOXICITY; LOW DRUG DOSE; MALE; MONOTHERAPY; NONHUMAN; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; OXIDATIVE STRESS; PHENOTYPE; RAT; SENSITIVITY AND SPECIFICITY; UNINDEXED SEQUENCE;

EID: 33845987713     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.31.491     Document Type: Article

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