-
1
-
-
0027953703
-
Insulin action, diabeto genes, and the cause of type II diabetes (Banting Lecture)
-
Kahn CR: Insulin action, diabetogenes, and the cause of type II diabetes (Banting Lecture). Diabetes 43:1066-1084, 1994
-
(1994)
Diabetes
, vol.43
, pp. 1066-1084
-
-
Kahn, C.R.1
-
2
-
-
0029873574
-
Genetics of non-insulin-dependent (type II) diabetes mellitus
-
Kahn CR, Vicent D, Doria A: Genetics of non-insulin-dependent (type II) diabetes mellitus. Annu Rev Med 47:509-531, 1996
-
(1996)
Annu Rev Med
, vol.47
, pp. 509-531
-
-
Kahn, C.R.1
Vicent, D.2
Doria, A.3
-
3
-
-
0035787083
-
Genetic determinants of type 2 diabetes
-
Froguel P, Velho G: Genetic determinants of type 2 diabetes. Recent Prog Horm Res 56:91-105, 2001
-
(2001)
Recent Prog Horm Res
, vol.56
, pp. 91-105
-
-
Froguel, P.1
Velho, G.2
-
4
-
-
0000689386
-
Familial syndromes of hyperproinsulinemia and hyperinsulinemia with mild diabetes
-
Scriver CR, Beaudet AL, Sly WS, Valle D, Eds. New York, McGraw, Hill
-
Steiner DF, Tager HS, Nanjo K, Chan SJ, Rubenstein AH: Familial syndromes of hyperproinsulinemia and hyperinsulinemia with mild diabetes. In The Metabolic and Molecular Bases of Inherited Disease. Scriver CR, Beaudet AL, Sly WS, Valle D, Eds. New York, McGraw-Hill, 1995, p. 897-904
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 897-904
-
-
Steiner, D.F.1
Tager, H.S.2
Nanjo, K.3
Chan, S.J.4
Rubenstein, A.H.5
-
5
-
-
0000743525
-
Diabetes mellitus
-
Scriver CR, Beaudet AL, Sly WS, Valle D, Eds. New York, McGraw, Hill
-
Taylor SI: Diabetes mellitus. In The Metabolic and Molecular Bases of Inherited Disease. Scriver CR, Beaudet AL, Sly WS, Valle D, Eds. New York, McGraw-Hill, 1995, p. 843-896
-
(1995)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 843-896
-
-
Taylor, S.I.1
-
6
-
-
0035960122
-
Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
-
Fajans SS, Bell GI, Polonsky KS: Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 345:971-980, 2001
-
(2001)
N Engl J Med
, vol.345
, pp. 971-980
-
-
Fajans, S.S.1
Bell, G.I.2
Polonsky, K.S.3
-
7
-
-
0028328317
-
A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA
-
Kadowaki T, Kadowaki H, Mori Y, Tobe K, Sakuta R, Suzuki Y, Tanabe Y, Sakura H, Awata T, Goto Y, et al: A subtype of diabetes mellitus associated with a mutation of mitochondrial DNA. N Engl J Med 330:962-968, 1994
-
(1994)
N Engl J Med
, vol.330
, pp. 962-968
-
-
Kadowaki, T.1
Kadowaki, H.2
Mori, Y.3
Tobe, K.4
Sakuta, R.5
Suzuki, Y.6
Tanabe, Y.7
Sakura, H.8
Awata, T.9
Goto, Y.10
-
8
-
-
0035106310
-
Putting the genes for type II diabetes on the map
-
Almind K, Doria A, Kahn CR: Putting the genes for type II diabetes on the map. Nat Med 7:277-279, 2001
-
(2001)
Nat Med
, vol.7
, pp. 277-279
-
-
Almind, K.1
Doria, A.2
Kahn, C.R.3
-
9
-
-
0015381515
-
The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains
-
Hummel KP, Coleman DL, Lane PW: The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains. Biochem Genet 7:1-13, 1972
-
(1972)
Biochem Genet
, vol.7
, pp. 1-13
-
-
Hummel, K.P.1
Coleman, D.L.2
Lane, P.W.3
-
10
-
-
0027508603
-
Obesity genes and diabetes induction in the mouse
-
Leiter EH: Obesity genes and diabetes induction in the mouse. Crit Rev Food Sci Nutr 33:333-338, 1993
-
(1993)
Crit Rev Food Sci Nutr
, vol.33
, pp. 333-338
-
-
Leiter, E.H.1
-
11
-
-
0032104113
-
Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model
-
Mehrabian M, Wen PZ, Fisler J, Davis RC, Lusis AJ: Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model. J Clin Invest 101:2485-2496, 1998
-
(1998)
J Clin Invest
, vol.101
, pp. 2485-2496
-
-
Mehrabian, M.1
Wen, P.Z.2
Fisler, J.3
Davis, R.C.4
Lusis, A.J.5
-
12
-
-
0000184456
-
BSB: A new mouse model of multigenic obesity
-
Fisler JS, Warden CH, Pace MJ, Lusis AJ: BSB: a new mouse model of multigenic obesity. Obes Res 1:271-280, 1993
-
(1993)
Obes Res
, vol.1
, pp. 271-280
-
-
Fisler, J.S.1
Warden, C.H.2
Pace, M.J.3
Lusis, A.J.4
-
13
-
-
0028937971
-
Identification of four chromosomal loci determining obesity in a multifactorial mouse model
-
Warden CH, Fisler JS, Shoemaker SM, Wen PZ, Svenson KL, Pace MJ, Lusis AJ: Identification of four chromosomal loci determining obesity in a multifactorial mouse model. J Clin Invest 95:1545-1552, 1995
-
(1995)
J Clin Invest
, vol.95
, pp. 1545-1552
-
-
Warden, C.H.1
Fisler, J.S.2
Shoemaker, S.M.3
Wen, P.Z.4
Svenson, K.L.5
Pace, M.J.6
Lusis, A.J.7
-
14
-
-
0015864927
-
The influence of genetic background on the expression of the obese (Ob) gene in the mouse
-
Coleman DL, Hummel KP: The influence of genetic background on the expression of the obese (Ob) gene in the mouse. Diabetologia 9:287-293, 1973
-
(1973)
Diabetologia
, vol.9
, pp. 287-293
-
-
Coleman, D.L.1
Hummel, K.P.2
-
15
-
-
0034525135
-
Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus
-
Kahn CR, Bruning JC, Michael MD, Kulkarni RN: Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus. J Pediatr Endocrinol Metab 13 (Suppl. 6):1377-1384, 2000
-
(2000)
J Pediatr Endocrinol Metab
, vol.13
, Issue.SUPPL. 6
, pp. 1377-1384
-
-
Kahn, C.R.1
Bruning, J.C.2
Michael, M.D.3
Kulkarni, R.N.4
-
16
-
-
0002399350
-
Genetic models of insulin resistance: Alterations in β-cell biology
-
Habener JF, Hussain M, Eds. New York, Kluwer Academic
-
Kulkarni RN, Kahn CR: Genetic models of insulin resistance: alterations in β-cell biology. In Molecular Basis of Pancreas Development and Function. Habener JF, Hussain M, Eds. New York, Kluwer Academic, 2001, p. 299-323
-
(2001)
Molecular Basis of Pancreas Development and Function
, pp. 299-323
-
-
Kulkarni, R.N.1
Kahn, C.R.2
-
17
-
-
0035287508
-
Modifier genes in mice and humans
-
Nadeau JH: Modifier genes in mice and humans. Nat Rev Genet 2:165-174, 2001
-
(2001)
Nat Rev Genet
, vol.2
, pp. 165-174
-
-
Nadeau, J.H.1
-
18
-
-
0034079629
-
Genetic modifiers of the insulin resistance phenotype in mice
-
Kido Y, Philippe N, Schaffer AA, Accili D: Genetic modifiers of the insulin resistance phenotype in mice. Diabetes 49:589-596, 2000
-
(2000)
Diabetes
, vol.49
, pp. 589-596
-
-
Kido, Y.1
Philippe, N.2
Schaffer, A.A.3
Accili, D.4
-
19
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
-
Bruning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR: Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell 88:561-572, 1997
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Bruning, J.C.1
Winnay, J.2
Bonner-Weir, S.3
Taylor, S.I.4
Accili, D.5
Kahn, C.R.6
-
20
-
-
0033636523
-
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction
-
Michael MD, Kulkarni RN, Postic C, Previs SF, Shulman GI, Magnuson MA, Kahn CR: Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Mol Cell 6:87-97, 2000
-
(2000)
Mol Cell
, vol.6
, pp. 87-97
-
-
Michael, M.D.1
Kulkarni, R.N.2
Postic, C.3
Previs, S.F.4
Shulman, G.I.5
Magnuson, M.A.6
Kahn, C.R.7
-
21
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes
-
Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR: Tissue-specific knockout of the insulin receptor in pancreatic β cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 96:329-339, 1999
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
Bruning, J.C.2
Winnay, J.N.3
Postic, C.4
Magnuson, M.A.5
Kahn, C.R.6
-
22
-
-
0028032895
-
Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene
-
Araki E, Lipes MA, Patti ME, Bruning JC, Haag BL III, Johnson RS, Kahn CR: Alternative pathway of insulin signaling in mice with targeted disruption of the IRS-1 gene. Nature 372:186-190, 1994
-
(1994)
Nature
, vol.372
, pp. 186-190
-
-
Araki, E.1
Lipes, M.A.2
Patti, M.E.3
Bruning, J.C.4
Haag B.L. III5
Johnson, R.S.6
Kahn, C.R.7
-
23
-
-
0037039317
-
Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase
-
Ueki K, Yballe CM, Brachmann SM, Vicent D, Watt JM, Kahn CR, Cantley LC: Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase. Proc Natl Acad Sci U S A 99:419-424, 2002
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 419-424
-
-
Ueki, K.1
Yballe, C.M.2
Brachmann, S.M.3
Vicent, D.4
Watt, J.M.5
Kahn, C.R.6
Cantley, L.C.7
-
24
-
-
0042570843
-
Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance
-
Virkamaki A, Ueki K, Kahn CR: Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance. J Clin Invest 103:931-943, 1999
-
(1999)
J Clin Invest
, vol.103
, pp. 931-943
-
-
Virkamaki, A.1
Ueki, K.2
Kahn, C.R.3
-
25
-
-
0010319112
-
Mutations in the insulin receptor gene in patients with genetic syndromes of extreme insulin resistance
-
Draznin B, LeRoith D, Eds. Ottowa, Canada, Humana Press
-
Taylor SI, Wertheimer E, Hone J, Levy-Toledano R, Quon MJ, Barbetti F, Suzuki Y, Roach P, Koller E, Haft CR, de Laat SW, Cama A, Accili D: Mutations in the insulin receptor gene in patients with genetic syndromes of extreme insulin resistance. In Molecular Biology of Diabetes II: Insulin Action, Effects on Gene Expression and Regulation, and Transport. Draznin B, LeRoith D, Eds. Ottowa, Canada, Humana Press, 1994, p. 1-23
-
(1994)
Molecular Biology of Diabetes II: Insulin Action, Effects on Gene Expression and Regulation, and Transport
, pp. 1-23
-
-
Taylor, S.I.1
Wertheimer, E.2
Hone, J.3
Levy-Toledano, R.4
Quon, M.J.5
Barbetti, F.6
Suzuki, Y.7
Roach, P.8
Koller, E.9
Haft, C.R.10
De Laat, S.W.11
Cama, A.12
Accili, D.13
-
26
-
-
0027367546
-
Amino acid polymorphisms of insulin receptor substrate-1 in non-insulindependent diabetes mellitus
-
Almind K, Bjorbaek C, Vestergaard H, Hansen T, Echwald SM, Pedersen O: Amino acid polymorphisms of insulin receptor substrate-1 in non-insulindependent diabetes mellitus. Lancet 342:828-832, 1993
-
(1993)
Lancet
, vol.342
, pp. 828-832
-
-
Almind, K.1
Bjorbaek, C.2
Vestergaard, H.3
Hansen, T.4
Echwald, S.M.5
Pedersen, O.6
-
27
-
-
0035185021
-
The forkhead transcription factor Foxol (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
-
Nakae J, Kitamura T, Silver DL, Accili D: The forkhead transcription factor Foxol (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J Clin Invest 108:1359-1367, 2001
-
(2001)
J Clin Invest
, vol.108
, pp. 1359-1367
-
-
Nakae, J.1
Kitamura, T.2
Silver, D.L.3
Accili, D.4
-
28
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBb)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EBI, Kaestner KH, Bartolomei MS, Shulman GI, Birnbaum MJ: Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBb). Science 292:1728-1731, 2001
-
(2001)
Science
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw, E.B.I.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
29
-
-
0037486225
-
Viral interactions with pancreatic β-cells
-
Lefebvre PJ, Pipeleers D, Eds. Berlin, Springer Verlag
-
Leiter EH, Wilson GL: Viral interactions with pancreatic β-cells. In The Pathology of the Endocrine Pancreas in Diabetes. Lefebvre PJ, Pipeleers D, Eds. Berlin, Springer Verlag, 1988, p. 85
-
(1988)
The Pathology of the Endocrine Pancreas in Diabetes
, pp. 85
-
-
Leiter, E.H.1
Wilson, G.L.2
-
30
-
-
0024215005
-
Genetic analysis of glucose tolerance in inbred mouse strains: Evidence for polygenic control
-
Kaku K, Fiedorek FTJ, Province M, Permutt MA: Genetic analysis of glucose tolerance in inbred mouse strains: evidence for polygenic control. Diabetes 37:707-713, 1988
-
(1988)
Diabetes
, vol.37
, pp. 707-713
-
-
Kaku, K.1
Fiedorek, F.T.J.2
Province, M.3
Permutt, M.A.4
-
31
-
-
0029163399
-
Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse
-
Paigen B: Genetics of responsiveness to high-fat and high-cholesterol diets in the mouse. Am J Clin Nutr 62:458S-462S, 1995
-
(1995)
Am J Clin Nutr
, vol.62
-
-
Paigen, B.1
-
32
-
-
0028032894
-
Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1
-
Tamemoto H, Kadowaki T, Tobe K, Yagi T, Sakura H, Hayakawa T, Terauchi Y, Ueki K, Kaburagi Y, Satoh S, Sekihara H, Yoshioka S, Horikoshi H, Furuta Y, Ikawa Y, Kasuga M, Yazaki Y, Aizawa S: Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature 372:182-186, 1994
-
(1994)
Nature
, vol.372
, pp. 182-186
-
-
Tamemoto, H.1
Kadowaki, T.2
Tobe, K.3
Yagi, T.4
Sakura, H.5
Hayakawa, T.6
Terauchi, Y.7
Ueki, K.8
Kaburagi, Y.9
Satoh, S.10
Sekihara, H.11
Yoshioka, S.12
Horikoshi, H.13
Furuta, Y.14
Ikawa, Y.15
Kasuga, M.16
Yazaki, Y.17
Aizawa, S.18
-
33
-
-
0033305504
-
Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice
-
Pete G, Fuller CR, Oldham JM, Smith DR, D'Ercole AJ, Kahn CR, Lund PK: Postnatal growth responses to insulin-like growth factor I in insulin receptor substrate-1-deficient mice. Endocrinology 140:5478-5487, 1999
-
(1999)
Endocrinology
, vol.140
, pp. 5478-5487
-
-
Pete, G.1
Fuller, C.R.2
Oldham, J.M.3
Smith, D.R.4
D'Ercole, A.J.5
Kahn, C.R.6
Lund, P.K.7
-
34
-
-
0021225459
-
Effect of genetic background on the capacity for islet cell replication in mice
-
Swenne I, Andersson A: Effect of genetic background on the capacity for islet cell replication in mice. Diabetologia 27:464-467, 1984
-
(1984)
Diabetologia
, vol.27
, pp. 464-467
-
-
Swenne, I.1
Andersson, A.2
|