-
1
-
-
2342510386
-
Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
-
Dor Y, Brown J, Martinez OI, Melton DA: Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429:41-46, 2004
-
(2004)
Nature
, vol.429
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
2
-
-
33644835007
-
Growth factors and beta cell replication
-
Vasavada RC, Gonzalez-Pertusa JA, Fujinaka Y, Fiaschi-Taesch N, Cozar-Castellano I, Garcia-Ocana A: Growth factors and beta cell replication. Int J Biochem Cell Biol 38:931-950, 2006
-
(2006)
Int J Biochem Cell Biol
, vol.38
, pp. 931-950
-
-
Vasavada, R.C.1
Gonzalez-Pertusa, J.A.2
Fujinaka, Y.3
Fiaschi-Taesch, N.4
Cozar-Castellano, I.5
Garcia-Ocana, A.6
-
3
-
-
0031916976
-
The physiology of parathyroid hormone-related protein: An emerging role as a developmental factor
-
Wysolmerski JJ, Stewart AF: The physiology of parathyroid hormone-related protein: an emerging role as a developmental factor. Annu Rev Physiol 60:431-460, 1998
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 431-460
-
-
Wysolmerski, J.J.1
Stewart, A.F.2
-
4
-
-
0028465518
-
Molecular cloning and characterization of a parathyroid hormone/parathyroid hormone-related peptide receptor: A member of an ancient family of G protein-coupled receptors
-
Juppner H: Molecular cloning and characterization of a parathyroid hormone/parathyroid hormone-related peptide receptor: a member of an ancient family of G protein-coupled receptors. Curr Opin Nephrol Hypertens 3:371-378, 1994
-
(1994)
Curr Opin Nephrol Hypertens
, vol.3
, pp. 371-378
-
-
Juppner, H.1
-
5
-
-
9444254643
-
Characterization of mice doubly transgenic for parathyroid hormone-related protein and murine placental lactogen: A novel role for placental lactogen in pancreatic β-cell survival
-
Fujinaka Y, Sipula D, Garcia-Ocana A, Vasavada RC: Characterization of mice doubly transgenic for parathyroid hormone-related protein and murine placental lactogen: a novel role for placental lactogen in pancreatic β-cell survival. Diabetes 53:3120-3130, 2004
-
(2004)
Diabetes
, vol.53
, pp. 3120-3130
-
-
Fujinaka, Y.1
Sipula, D.2
Garcia-Ocana, A.3
Vasavada, R.C.4
-
6
-
-
0343415078
-
Parathyroid hormone-related peptide stimulates DNA synthesis and insulin secretion in pancreatic islets
-
Villanueva-Penacarrillo ML, Cancelas J, de Miguel F, Redondo A, Valin A, Valverde I, Esbrit P: Parathyroid hormone-related peptide stimulates DNA synthesis and insulin secretion in pancreatic islets. J Endocrinol 163:403-408, 1999
-
(1999)
J Endocrinol
, vol.163
, pp. 403-408
-
-
Villanueva-Penacarrillo, M.L.1
Cancelas, J.2
de Miguel, F.3
Redondo, A.4
Valin, A.5
Valverde, I.6
Esbrit, P.7
-
7
-
-
0035922142
-
PTHrP increases pancreatic β-cell-specific functions in well-differentiated cells
-
Sawada Y, Zhang B, Okajima T, Izumi T, Takeuchi T: PTHrP increases pancreatic β-cell-specific functions in well-differentiated cells. Mol Cell Endocrinol 182:265-275, 2001
-
(2001)
Mol Cell Endocrinol
, vol.182
, pp. 265-275
-
-
Sawada, Y.1
Zhang, B.2
Okajima, T.3
Izumi, T.4
Takeuchi, T.5
-
8
-
-
0034107193
-
Hepatocyte growth factor/scatter factor-induced intracellular signalling
-
Stuart KA, Riordan SM, Lidder S, Crostella L, Williams R, Skouteris GG: Hepatocyte growth factor/scatter factor-induced intracellular signalling. Int J Exp Pathol 81:17-30, 2000
-
(2000)
Int J Exp Pathol
, vol.81
, pp. 17-30
-
-
Stuart, K.A.1
Riordan, S.M.2
Lidder, S.3
Crostella, L.4
Williams, R.5
Skouteris, G.G.6
-
9
-
-
0030015057
-
A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth
-
Otonkoski T, Cirulli V, Beattie M, Mally MI, Soto G, Rubin JS, Hayek A: A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth. Endocrinology 137:3131-3139, 1996
-
(1996)
Endocrinology
, vol.137
, pp. 3131-3139
-
-
Otonkoski, T.1
Cirulli, V.2
Beattie, M.3
Mally, M.I.4
Soto, G.5
Rubin, J.S.6
Hayek, A.7
-
10
-
-
21344442148
-
Targeted inactivation of hepatocyte growth factor receptor c-met in β-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of β-cell mass
-
Roccisana J, Reddy V, Vasavada RC, Gonzalez-Pertusa JA, Magnuson MA, Garcia-Ocana A: Targeted inactivation of hepatocyte growth factor receptor c-met in β-cells leads to defective insulin secretion and GLUT-2 downregulation without alteration of β-cell mass. Diabetes 54:2090-2102, 2005
-
(2005)
Diabetes
, vol.54
, pp. 2090-2102
-
-
Roccisana, J.1
Reddy, V.2
Vasavada, R.C.3
Gonzalez-Pertusa, J.A.4
Magnuson, M.A.5
Garcia-Ocana, A.6
-
11
-
-
0036238957
-
Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations
-
Gahr S, Merger M, Bollheimer LC, Hammerschmied CG, Scholmerich J, Hugl SR: Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations. J Mol Endocrinol 28:99-110, 2002
-
(2002)
J Mol Endocrinol
, vol.28
, pp. 99-110
-
-
Gahr, S.1
Merger, M.2
Bollheimer, L.C.3
Hammerschmied, C.G.4
Scholmerich, J.5
Hugl, S.R.6
-
12
-
-
13344270898
-
Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia
-
Vasavada RC, Cavaliere C, D'Ercole AJ, Dann P, Burtis WJ, Madlener AL, Zawalich K, Zawalich W, Philbrick WM, Stewart AF: Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia. J Biol Chem 271:1200-1208, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 1200-1208
-
-
Vasavada, R.C.1
Cavaliere, C.2
D'Ercole, A.J.3
Dann, P.4
Burtis, W.J.5
Madlener, A.L.6
Zawalich, K.7
Zawalich, W.8
Philbrick, W.M.9
Stewart, A.F.10
-
13
-
-
0031731218
-
Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse
-
Porter SE, Sorenson RL, Dann P, Garcia-Ocaña A, Stewart AF, Vasavada RC: Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse. Endocrinology 139: 3743-3751, 1998
-
(1998)
Endocrinology
, vol.139
, pp. 3743-3751
-
-
Porter, S.E.1
Sorenson, R.L.2
Dann, P.3
Garcia-Ocaña, A.4
Stewart, A.F.5
Vasavada, R.C.6
-
14
-
-
0033954474
-
Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia
-
Garcia-Ocaña A, Takane KK, Syed MA, Philbrick WM, Vasavada RC, Stewart AF: Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia. J Biol Chem 275:1226-1232, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 1226-1232
-
-
Garcia-Ocaña, A.1
Takane, K.K.2
Syed, M.A.3
Philbrick, W.M.4
Vasavada, R.C.5
Stewart, A.F.6
-
15
-
-
0035650568
-
Transgenic overexpression of hepatocyte growth factor in the β-cell markedly improves islet function and islet transplant outcomes in mice
-
Garcia-Ocana A, Vasavada RC, Cebrian A, Reddy V, Takane KK, Lopez-Talavera JC, Stewart AF: Transgenic overexpression of hepatocyte growth factor in the β-cell markedly improves islet function and islet transplant outcomes in mice. Diabetes 50:2752-2762, 2001
-
(2001)
Diabetes
, vol.50
, pp. 2752-2762
-
-
Garcia-Ocana, A.1
Vasavada, R.C.2
Cebrian, A.3
Reddy, V.4
Takane, K.K.5
Lopez-Talavera, J.C.6
Stewart, A.F.7
-
16
-
-
0027194337
-
Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells
-
Wang TC, Bonner-Weir S, Oates PS, Chulak M, Simon B, Merlino GT, Schmidt EV, Brand SJ: Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells. J Clin Invest 92:1349-1356, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 1349-1356
-
-
Wang, T.C.1
Bonner-Weir, S.2
Oates, P.S.3
Chulak, M.4
Simon, B.5
Merlino, G.T.6
Schmidt, E.V.7
Brand, S.J.8
-
17
-
-
24144446405
-
Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycemia in diabetic NOD mice
-
Suarez-Pinzon WL, Yan Y, Power R, Brand SJ, Rabinovitch A: Combination therapy with epidermal growth factor and gastrin increases β-cell mass and reverses hyperglycemia in diabetic NOD mice. Diabetes 54:2596-2601, 2005
-
(2005)
Diabetes
, vol.54
, pp. 2596-2601
-
-
Suarez-Pinzon, W.L.1
Yan, Y.2
Power, R.3
Brand, S.J.4
Rabinovitch, A.5
-
18
-
-
0034651539
-
Multiple pathways control protein kinase C phosphorylation
-
Parekh DB, Ziegler W, Parker PJ: Multiple pathways control protein kinase C phosphorylation. EMBO J 19:496-503, 2000
-
(2000)
EMBO J
, vol.19
, pp. 496-503
-
-
Parekh, D.B.1
Ziegler, W.2
Parker, P.J.3
-
19
-
-
0032563936
-
Regulation of protein kinase ζ by PI 3-kinase and PDK-1
-
Chou MM, Hou W, Johnson J, Graham LK, Lee MH, Chen C-S, Newton AC, Schaffhausen BS, Toker A: Regulation of protein kinase ζ by PI 3-kinase and PDK-1. Curr Biol 8:1069-1077, 1998
-
(1998)
Curr Biol
, vol.8
, pp. 1069-1077
-
-
Chou, M.M.1
Hou, W.2
Johnson, J.3
Graham, L.K.4
Lee, M.H.5
Chen, C.-S.6
Newton, A.C.7
Schaffhausen, B.S.8
Toker, A.9
-
20
-
-
0027178812
-
Protein kinase C ζ isoform is critical for mitogenic signal transduction
-
Berra E, Diaz-Meco MT, Dominguez I, Municio MM, Sanz L, Lozano J, Chapkin RS, Moscat J: Protein kinase C ζ isoform is critical for mitogenic signal transduction. Cell 74:555-563, 1993
-
(1993)
Cell
, vol.74
, pp. 555-563
-
-
Berra, E.1
Diaz-Meco, M.T.2
Dominguez, I.3
Municio, M.M.4
Sanz, L.5
Lozano, J.6
Chapkin, R.S.7
Moscat, J.8
-
21
-
-
0033839813
-
Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines
-
Donson AM, Banerjee A, Gamboni-Robertson F, Fleitz JM, Foreman NK: Protein kinase C zeta isoform is critical for proliferation in human glioblastoma cell lines. J Neurooncol 47:109-115, 2000
-
(2000)
J Neurooncol
, vol.47
, pp. 109-115
-
-
Donson, A.M.1
Banerjee, A.2
Gamboni-Robertson, F.3
Fleitz, J.M.4
Foreman, N.K.5
-
22
-
-
0347990598
-
Induction of β-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D(1)
-
Cozar-Castellano I, Takane KK, Bottino R, Balamurugan AN, Stewart AF: Induction of β-cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D(1). Diabetes 53:149-159, 2004
-
(2004)
Diabetes
, vol.53
, pp. 149-159
-
-
Cozar-Castellano, I.1
Takane, K.K.2
Bottino, R.3
Balamurugan, A.N.4
Stewart, A.F.5
-
23
-
-
0035489990
-
Protein kinase C ζ activation mediates glucagon-like peptide-1-induced pancreatic β-cell proliferation
-
Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, Prentki M: Protein kinase C ζ activation mediates glucagon-like peptide-1-induced pancreatic β-cell proliferation. Diabetes 50:2237-2243, 2001
-
(2001)
Diabetes
, vol.50
, pp. 2237-2243
-
-
Buteau, J.1
Foisy, S.2
Rhodes, C.J.3
Carpenter, L.4
Biden, T.J.5
Prentki, M.6
-
24
-
-
0037414812
-
Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death
-
Garcia-Ocana A, Takane KK, Reddy VT, Lopez-Talavera JC, Vasavada RC, Stewart AF: Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death. J Biol Chem 278:343-351, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 343-351
-
-
Garcia-Ocana, A.1
Takane, K.K.2
Reddy, V.T.3
Lopez-Talavera, J.C.4
Vasavada, R.C.5
Stewart, A.F.6
-
25
-
-
0028690027
-
Use of recombinant adenovirus for metabolic engineering of mammalian cells
-
Becker TC, Noel RJ, Coats WS, Gomez-Foix AM, Alam T, Gerard RD, Newgard CB: Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol 43:161-189, 1994
-
(1994)
Methods Cell Biol
, vol.43
, pp. 161-189
-
-
Becker, T.C.1
Noel, R.J.2
Coats, W.S.3
Gomez-Foix, A.M.4
Alam, T.5
Gerard, R.D.6
Newgard, C.B.7
-
26
-
-
0032932198
-
p70 S6 kinase is regulated by protein kinase C ζ and participates in a phosphoinositide 3-kinase-regulated signaling complex
-
Romanelli A, Martin KA, Toker A, Blenis J: p70 S6 kinase is regulated by protein kinase C ζ and participates in a phosphoinositide 3-kinase-regulated signaling complex. Mol Cell Biol 19:2921-2928, 1999
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2921-2928
-
-
Romanelli, A.1
Martin, K.A.2
Toker, A.3
Blenis, J.4
-
27
-
-
0036789242
-
Overexpression of parathyroid hormone-related protein inhibits pancreatic β-cell death in vivo and in vitro
-
Cebrian A, García-Ocaña A, Takane K, Sipula D, Stewart AF, Vasavada RC: Overexpression of parathyroid hormone-related protein inhibits pancreatic β-cell death in vivo and in vitro. Diabetes 51:3003-3013, 2002
-
(2002)
Diabetes
, vol.51
, pp. 3003-3013
-
-
Cebrian, A.1
García-Ocaña, A.2
Takane, K.3
Sipula, D.4
Stewart, A.F.5
Vasavada, R.C.6
-
28
-
-
20044384383
-
Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice
-
Rao P, Roccisana J, Takane KK, Bottino R, Zhao A, Trucco M, Garcia-Ocana A: Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice. Diabetes 54:1664-1675, 2005
-
(2005)
Diabetes
, vol.54
, pp. 1664-1675
-
-
Rao, P.1
Roccisana, J.2
Takane, K.K.3
Bottino, R.4
Zhao, A.5
Trucco, M.6
Garcia-Ocana, A.7
-
29
-
-
0030603158
-
Inhibition of protein kinase C mu by various inhibitors: Differentiation from protein kinase c isoenzymes
-
Gschwendt M, Dieterich S, Rennecke J, Kittstein W, Mueller HJ, Johannes FJ: Inhibition of protein kinase C mu by various inhibitors: differentiation from protein kinase c isoenzymes. FEBS Lett 392:77-80, 1996
-
(1996)
FEBS Lett
, vol.392
, pp. 77-80
-
-
Gschwendt, M.1
Dieterich, S.2
Rennecke, J.3
Kittstein, W.4
Mueller, H.J.5
Johannes, F.J.6
-
30
-
-
0032504211
-
Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent: Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells
-
Hugl SR, White MF, Rhodes CJ: Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent: synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem 273:17771-17779, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 17771-17779
-
-
Hugl, S.R.1
White, M.F.2
Rhodes, C.J.3
-
31
-
-
0032768616
-
Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells
-
Buteau J, Roduit R, Susini S, Prentki M: Glucagon-like peptide-1 promotes DNA synthesis, activates phosphatidylinositol 3-kinase and increases transcription factor pancreatic and duodenal homeobox gene 1 (PDX-1) DNA binding activity in beta (INS-1)-cells. Diabetologia 42:856-864, 1999
-
(1999)
Diabetologia
, vol.42
, pp. 856-864
-
-
Buteau, J.1
Roduit, R.2
Susini, S.3
Prentki, M.4
-
32
-
-
0035877778
-
Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1)
-
Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG Jr, Rhodes CJ: Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). J Biol Chem 276:21110-21120, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 21110-21120
-
-
Dickson, L.M.1
Lingohr, M.K.2
McCuaig, J.3
Hugl, S.R.4
Snow, L.5
Kahn, B.B.6
Myers Jr, M.G.7
Rhodes, C.J.8
-
33
-
-
0034838323
-
Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling
-
Trumper A, Trumper K, Trusheim H, Arnold R, Goke B, Horsch D: Glucose-dependent insulinotropic polypeptide is a growth factor for beta (INS-1) cells by pleiotropic signaling. Mol Endocrinol 15:1559-1570, 2001
-
(2001)
Mol Endocrinol
, vol.15
, pp. 1559-1570
-
-
Trumper, A.1
Trumper, K.2
Trusheim, H.3
Arnold, R.4
Goke, B.5
Horsch, D.6
-
34
-
-
33846435771
-
-
Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghe C, Isgaard J, Papotti M, Ghigo E, Muccioli G: Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3′,5′-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling. Endocrinology 148:512-529, 2007
-
Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghe C, Isgaard J, Papotti M, Ghigo E, Muccioli G: Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3′,5′-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling. Endocrinology 148:512-529, 2007
-
-
-
-
35
-
-
0034836846
-
Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways
-
Carpio L, Gladu J, Goltzman D, Rabbani SA: Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways. Am J Physiol Endocrinol Metab 281:E489-E499, 2001
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Carpio, L.1
Gladu, J.2
Goltzman, D.3
Rabbani, S.A.4
-
36
-
-
33644552719
-
G-protein-coupled receptors and tyrosine kinases: Crossroads in cell signaling and regulation
-
Gavi S, Shumay E, Wang H-Y, Malbon CC: G-protein-coupled receptors and tyrosine kinases: crossroads in cell signaling and regulation. Trends Endocrinol Metab 17:48-54, 2006
-
(2006)
Trends Endocrinol Metab
, vol.17
, pp. 48-54
-
-
Gavi, S.1
Shumay, E.2
Wang, H.-Y.3
Malbon, C.C.4
-
37
-
-
0035146675
-
MEK5, a new target of the atypical protein kinase c isoforms in mitogenic signaling
-
Diaz-Meco MT, Moscat J: MEK5, a new target of the atypical protein kinase c isoforms in mitogenic signaling. Mol Cell Biol 21:1218-1227, 2001
-
(2001)
Mol Cell Biol
, vol.21
, pp. 1218-1227
-
-
Diaz-Meco, M.T.1
Moscat, J.2
-
38
-
-
0027963204
-
Identification and subcellular characterization of protein kinase-C isoforms in insulinoma beta-cells and whole islets
-
Knutson KL, Hoenig M: Identification and subcellular characterization of protein kinase-C isoforms in insulinoma beta-cells and whole islets. Endocrinology 135:881-886, 1994
-
(1994)
Endocrinology
, vol.135
, pp. 881-886
-
-
Knutson, K.L.1
Hoenig, M.2
-
39
-
-
0042493623
-
Atypical protein kinase C isozyme ζ mediates carbachol-stimulated insulin secretion in RINm5F cells
-
Tang SH, Sharp GW: Atypical protein kinase C isozyme ζ mediates carbachol-stimulated insulin secretion in RINm5F cells. Diabetes 47:905-912, 1998
-
(1998)
Diabetes
, vol.47
, pp. 905-912
-
-
Tang, S.H.1
Sharp, G.W.2
-
40
-
-
33644772348
-
Dynamics of glucose-induced localization of PKC isoenzymes in pancreatic β-cells: Diabetes-related changes in the GK rat
-
Warwar N, Efendic S, Östenson C-G, Haber EP, Cerasi E, Nesher R: Dynamics of glucose-induced localization of PKC isoenzymes in pancreatic β-cells: diabetes-related changes in the GK rat. Diabetes 55:590-599, 2006
-
(2006)
Diabetes
, vol.55
, pp. 590-599
-
-
Warwar, N.1
Efendic, S.2
Östenson, C.-G.3
Haber, E.P.4
Cerasi, E.5
Nesher, R.6
-
41
-
-
0032926648
-
Possible involvement of atypical protein kinase C (PKC) in glucose-sensitive expression of the human insulin gene: DNA-binding activity and transcriptional activity of pancreatic and duodenal homeobox gene-1 (PDX-1) are enhanced via calphostin C-sensitive but phorbol 12-myristate 13-acetate (PMA) and Gö 6976-insensitive pathway
-
Furukawa N, Shirotani T, Araki E, Kaneko K, Todaka M, Matsumoto K, Tsuruzoe K, Motoshima H, Yoshizato K, Kishikawa H, Shichiri M: Possible involvement of atypical protein kinase C (PKC) in glucose-sensitive expression of the human insulin gene: DNA-binding activity and transcriptional activity of pancreatic and duodenal homeobox gene-1 (PDX-1) are enhanced via calphostin C-sensitive but phorbol 12-myristate 13-acetate (PMA) and Gö 6976-insensitive pathway. Endocr J 46:43-58, 1999
-
(1999)
Endocr J
, vol.46
, pp. 43-58
-
-
Furukawa, N.1
Shirotani, T.2
Araki, E.3
Kaneko, K.4
Todaka, M.5
Matsumoto, K.6
Tsuruzoe, K.7
Motoshima, H.8
Yoshizato, K.9
Kishikawa, H.10
Shichiri, M.11
-
42
-
-
33847388518
-
PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic β-cells
-
Miele C, Raciti GA, Cassese A, Romano C, Giacco F, Oriente F, Paturzo F, Andreozzi F, Zabatta A, Troncone G, Bosch F, Pujol A, Chneiweiss H, Formisano P, Beguinot F: PED/PEA-15 regulates glucose-induced insulin secretion by restraining potassium channel expression in pancreatic β-cells. Diabetes 56:622-633, 2007
-
(2007)
Diabetes
, vol.56
, pp. 622-633
-
-
Miele, C.1
Raciti, G.A.2
Cassese, A.3
Romano, C.4
Giacco, F.5
Oriente, F.6
Paturzo, F.7
Andreozzi, F.8
Zabatta, A.9
Troncone, G.10
Bosch, F.11
Pujol, A.12
Chneiweiss, H.13
Formisano, P.14
Beguinot, F.15
-
43
-
-
0036296861
-
PKC ζ enhances insulin-like growth factor 1-dependent mitogenic activity in the rat clonal beta cell line RIN 1046-38
-
Hennige AM, Fritsche A, Strack V, Weigert C, Mischak H, Borboni P, Renn W, Haring H-U, Kellerer M: PKC ζ enhances insulin-like growth factor 1-dependent mitogenic activity in the rat clonal beta cell line RIN 1046-38. Biochem Biophys Res Commun 290:85-90, 2002
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 85-90
-
-
Hennige, A.M.1
Fritsche, A.2
Strack, V.3
Weigert, C.4
Mischak, H.5
Borboni, P.6
Renn, W.7
Haring, H.-U.8
Kellerer, M.9
-
44
-
-
0027431089
-
Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells
-
Selbie LA, Schmitz-Peiffer C, Sheng Y, Biden TJ: Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells. J Biol Chem 268:24296-24302, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 24296-24302
-
-
Selbie, L.A.1
Schmitz-Peiffer, C.2
Sheng, Y.3
Biden, T.J.4
-
45
-
-
85047693987
-
PKC λ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells
-
Hashimoto K, Kido Y, Uchida T, Matsuda T, Suzuki K, Inoue H, Matsumoto M, Ogawa W, Maeda S, Fujihara H, Ueta Y, Uchiyama Y, Akimoto K, Ohno S, Noda T, Kasuga M: PKC λ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells. J Clin Invest 115:138-145, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 138-145
-
-
Hashimoto, K.1
Kido, Y.2
Uchida, T.3
Matsuda, T.4
Suzuki, K.5
Inoue, H.6
Matsumoto, M.7
Ogawa, W.8
Maeda, S.9
Fujihara, H.10
Ueta, Y.11
Uchiyama, Y.12
Akimoto, K.13
Ohno, S.14
Noda, T.15
Kasuga, M.16
-
46
-
-
0037668996
-
Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta cells (INS-1)
-
Wrede CE, Dickson LM, Lingohr MK, Briaud I, Rhodes CJ: Fatty acid and phorbol ester-mediated interference of mitogenic signaling via novel protein kinase C isoforms in pancreatic beta cells (INS-1). J Mol Endocrinol 30:271-286, 2003
-
(2003)
J Mol Endocrinol
, vol.30
, pp. 271-286
-
-
Wrede, C.E.1
Dickson, L.M.2
Lingohr, M.K.3
Briaud, I.4
Rhodes, C.J.5
-
47
-
-
2942752110
-
Bi-directional regulation of Ser-985 phosphorylation of c-met via protein kinase C and protein phosphatase 2A involves c-Met activation and cellular responsiveness to hepatocyte growth factor
-
Hashigasako A, Machide M, Nakamura T, Matsumoto K, Nakamura T: Bi-directional regulation of Ser-985 phosphorylation of c-met via protein kinase C and protein phosphatase 2A involves c-Met activation and cellular responsiveness to hepatocyte growth factor. J Biol Chem 279:26445-26452, 2004
-
(2004)
J Biol Chem
, vol.279
, pp. 26445-26452
-
-
Hashigasako, A.1
Machide, M.2
Nakamura, T.3
Matsumoto, K.4
Nakamura, T.5
-
48
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P: Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351:95-105, 2000
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
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