Acidic environment activates inflammatory programs in fibroblasts via a cAMP-MAPK pathway

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1853, Issue 2, 2015, Pages 299-307

  Riemann, A ^a   Ihling, A ^a   Thomas, J ^a   Schneider, B ^a   Thews, O ^a   Gekle, M ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Acidosis; Fibroblast; Inflammation; MAP kinase signaling

Indexed keywords

CALCIUM; CYCLIC AMP; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRATE; NITRITE; PHOSPHATASE; PROTEIN; PROTEIN GPR132; PROTEIN GPR4; PROTEIN GPR68; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ACID; CCL2 PROTEIN, RAT; G PROTEIN COUPLED RECEPTOR; MESSENGER RNA; PTGS2 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; GENE; INFLAMMATION; METABOLIC ACIDOSIS; MICROENVIRONMENT; NONHUMAN; PH; PROTEIN EXPRESSION; RAT; SENSOR; ACIDOSIS; ANIMAL; BIOLOGICAL MODEL; ENZYME ACTIVATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME;

ACIDOSIS; ACIDS; ANIMALS; CHEMOKINE CCL2; CYCLIC AMP; CYCLOOXYGENASE 2; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE EXPRESSION REGULATION; INFLAMMATION; INTRACELLULAR SPACE; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RECEPTORS, G-PROTEIN-COUPLED; RNA, MESSENGER; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84913580231     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2014.11.022     Document Type: Article

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