Acid stress increases gene expression of proinflammatory cytokines in Madin-Darby canine kidney cells

American Journal of Physiology - Renal Physiology

Volumn 304, Issue 1, 2013, Pages

  Raj, Suraja ^a   Scott, David R ^a,b   Nguyen, Thomas ^a   Sachs, George ^a,b   Kraut, Jeffrey A ^a,b  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CCL7; Intracellular pH; Lubricin; MDCK cells; Metabolic acidosis; Proinflammatory cytokines

Indexed keywords

COLLAGENASE 3; COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 2; CYTOKINE; GELATINASE B; INTERLEUKIN 1ALPHA; LUBRICIN; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ACIDITY; ANIMAL CELL; ARTICLE; CELL PH; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; DOWN REGULATION; GENE EXPRESSION; HOUSEKEEPING GENE; INTRACELLULAR SPACE; KIDNEY INJURY; MDCK CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

EID: 84871895229     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00128.2012     Document Type: Article

References (35)

1. Arcuri F, Toti P, Buchwalder L, Casciaro A, Cintorino M, Schatz F, Rybalov B, Lockwood CJ. Mechanisms of leukocyte accumulation and activation in chorioamnionitis: interleukin 1 beta and tumor necrosis factor alpha enhance colony stimulating factor 2 expression in term decidua. Reprod Sci 16: 453-461, 2009.
2. Bensen JT, Langefeld CD, Li LW, Mccall CE, Cousart SL, Dryman BN, Freedman BI, Bowden DW. Association of an IL-1A 3'-UTR polymorphism with end-stage renal disease and IL-1 alpha expression. Kidney Int 63: 1211-1219, 2003.
3. Boulkroun S, Fay M, Zennaro MC, Escoubet B, Jaisser F, Blot-Chabaud M, Farman N, Courtois-Coutry N. Characterization of rat NDRG2 (N-Myc downstream regulated gene 2), a novel early mineralo-corticoid-specific induced gene. J Biol Chem 277: 31506-31515, 2002.
4. Bouyer P, Bradley SR, Zhao J, Wang W, Richerson GB, Boron WF. Effect of extracellular acid-base disturbances on the intracellular pH of neurones cultured from rat medullary raphe or hippocampus. J Physiol 559: 85-101, 2004.
5. Cheval L, Morla L, Elalouf JM, Doucet A. Kidney collecting duct acid-base "regulon". Physiol Genomics 27: 271-281, 2006.
6. Chiang CK, Hsu SP, Wu CT, Huang JW, Cheng HT, Chang YW, Hung KY, Wu KD, Liu SH. Endoplasmic reticulum stress implicated in the development of renal fibrosis. Mol Med 17: 1295-1305, 2011.
7. Graber ML, DiLillo DC, Friedman BL, Pastoriza-Munoz E. Characteristics of fluoroprobes for measuring intracellular pH. Anal Biochem 156: 202-212, 1986.
8. Gtgurevic L, Vukicevic S. ADAMTS4 as a biomarker and therapeutic target for chronic renal disease. Patent 0254997, 2012.
9. Herzlinger DA, Easton TG, Ojakian GK. The MDCK epithelial cell line expresses a cell surface antigen of the kidney distal tubule. J Cell Biol 93: 269-277, 1982.
10. Hu XL, Yao LB, Zhang YQ, Deng YC, Liu XP. Distribution characteristic of NDRG2 expression in human fetal tissues. Sheng Li Xue Bao 58: 331-336, 2006.
11. Huang dW, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4: 44-57, 2009.
12. Huang dW, Sherman BT, Tan Q, Kir J, Liu D, Bryant D, Guo Y, Stephens R, Baseler MW, Lane HC, Lempicki RA. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res 35: W169-W175, 2007.
13. Islam SA, Chang DS, Colvin RA, Byrne MH, McCully ML, Moser B, Lira SA, Charo IF, Luster AD. Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5(+) T(H)2 cells. Nat Immunol 12: 167-177, 2011.
14. Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J. Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int J Cancer 127: 332-344, 2010.
15. Kim HJ, Lee JS, Kim JD, Cha HJ, Kim A, Lee SK, Lee SC, Kwon BS, Mittler RS, Cho HR, Kwon B. Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation. Proc Natl Acad Sci USA 109: E13-E22, 2012.
16. Kraut JA. Effect of metabolic acidosis on progression of chronic kidney disease. Am J Physiol Renal Physiol 300: F828-F829, 2011.
17. Kraut JA, Madias NE. Metabolic acidosis: pathophysiology, diagnosis and management. Nat Rev Nephrol 6: 274-285, 2010.
18. Kunugi S, Shimizu A, Kuwahara N, Du X, Takahashi M, Terasaki Y, Fujita E, Mii A, Nagasaka S, Akimoto T, Masuda Y, Fukuda Y. Inhibition of matrix metalloproteinases reduces ischemia-reperfusion acute kidney injury. Lab Invest 91: 170-180, 2011.
19. Lee JW, Kim WH, Yeo J, Jung MH. ER stress is implicated in mitochondrial dysfunction-induced apoptosis of pancreatic beta cells. Mol Cells 30: 545-549, 2010.
20. Liu J, Zhang J, Wang X, Li Y, Chen Y, Li K, Zhang J, Yao L, Guo G. HIF-1 and NDRG2 contribute to hypoxia-induced radioresistance of cervical cancer Hela cells. Exp Cell Res 316: 1985-1993, 2010.
21. Ma T, Han L, Gao Y, Li L, Shang X, Hu W, Xue C. The endoplasmic reticulum stress-mediated apoptosis signal pathway is involved in sepsis-induced abnormal lymphocyte apoptosis. Eur Surg Res 41: 219-225, 2008.
22. Mitchelmore C, Buchmann-Moller S, Rask L, West MJ, Troncoso JC, Jensen NA. NDRG2: a novel Alzheimer's disease associated protein. Neurobiol Dis 16: 48-58, 2004.
23. Nowik M, Lecca MR, Velic A, Rehrauer H, Brandli AW, Wagner CA. Genome-wide gene expression profiling reveals renal genes regulated during metabolic acidosis. Physiol Genomics 32: 322-334, 2008.
24. Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11: 381-389, 2004.
25. Phisitkul S, Khanna A, Simoni J, Broglio K, Sheather S, Rajab MH, Wesson DE. Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR. Kidney Int 77: 617-623, 2010.
26. Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, Jay GD, Stewart M, Wang H, Warman ML, Carpten JD. The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest 115: 622-631, 2005.
27. Simonson MS, Ismail-Beigi F. Endothelin-1 increases collagen accumulation in renal mesangial cells by stimulating a chemokine and cytokine autocrine signaling loop. J Biol Chem 286: 11003-11008, 2011.
28. Sun X, Yang LV, Tiegs BC, Arend LJ, McGraw DW, Penn RB, Petrovic S. Deletion of the pH sensor GPR4 decreases renal acid excretion. J Am Soc Nephrol 21: 1745-1755, 2010.
29. Sun Y, Berger EJ, Zhao C, An KN, Amadio PC, Jay G. Mapping lubricin in canine musculoskeletal tissues. Connect Tissue Res 47: 215-221, 2006.
30. Takahashi K, Yamada M, Ohata H, Honda K, Yamada M. Ndrg2 promotes neurite outgrowth of NGF-differentiated PC12 cells. Neurosci Lett 388: 157-162, 2005.
31. Wang L, Liu N, Yao L, Li F, Zhang J, Deng Y, Liu J, Ji S, Yang A, Han H, Zhang Y, Zhang J, Han W, Liu X. NDRG2 is a new HIF-1 target gene necessary for hypoxia-induced apoptosis in A549 cells. Cell Physiol Biochem 21: 239-250, 2008.
32. Wesson DE, Simoni J. Acid retention during kidney failure induces endothelin and aldosterone production which lead to progressive GFR decline, a situation ameliorated by alkali diet. Kidney Int 78: 1128-1135, 2010.
33. Wu X, Guo R, Chen P, Wang Q, Cunningham PN. TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho-and myosin light chain kinase-dependent mechanism. Am J Physiol Renal Physiol 297: F316-F326, 2009.
34. Zhang T, Dayanandan B, Rouiller I, Lawrence EJ, Mandato CA. Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos. PLos One 6: e24698, 2011.
35. Zhang Y, Woodward VK, Shelton JM, Richardson JA, Zhou XJ, Link D, Kielar ML, Jeyarajah DR, Lu CY. Ischemia-reperfusion induces G-CSF gene expression by renal medullary thick ascending limb cells in vivo and in vitro. Am J Physiol Renal Physiol 286: F1193-F1201, 2004.