Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish

Chemosphere

Volumn 120, Issue , 2015, Pages 778-792

  Groh, Ksenia J ^a,b   Carvalho, Raquel N ^c   Chipman, James K ^d   Denslow, Nancy D ^e   Halder, Marlies ^c   Murphy, Cheryl A ^f   Roelofs, Dick ^g   Rolaki, Alexandra ^c   Schirmer, Kristin ^a,b,h   Watanabe, Karen H ⁱ  

^a SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

^b ETH ZURICH   (Switzerland)

^c JOINT RESEARCH CENTRE   (Italy)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^e UNIVERSITY OF FLORIDA   (United States)

^f MICHIGAN STATE UNIVERSITY   (United States)

^g VU UNIVERSITY AMSTERDAM   (Netherlands)

^h EPFL   (Switzerland)

ⁱ OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

3R (replacement, reduction, refinement); Adverse outcome pathway; Behavior; Cadmium; Pyrethroid; Selective serotonin reuptake inhibitor

Indexed keywords

CADMIUM; FISH; TOXICITY;

3R (REPLACEMENT, REDUCTION, REFINEMENT); ADVERSE OUTCOMES; BEHAVIOR; PYRETHROIDS; SELECTIVE SEROTONIN RE-UPTAKE INHIBITORS;

CHEMICAL CONTAMINATION;

CADMIUM; PYRETHROID; SEROTONIN UPTAKE INHIBITOR; POLLUTANT;

FISH; FOOD INTAKE; GROWTH RESPONSE; HAZARD ASSESSMENT; LOCOMOTION; METABOLISM; PYRETHROID; TOXICITY;

ADVERSE OUTCOME; ADVERSE OUTCOME PATHWAY; ANGUILLA ANGUILLA; ANIMAL BEHAVIOR; ATHERINOPS AFFINIS; ATLANTIC SALMON; BROOK TROUT; BROWN TROUT; CARP; CATOSTOMUS COMERSONI; CELL PROLIFERATION; CHRONIC TOXICITY; DEVELOPMENT; ENERGY RESOURCE; FISH; FOOD INTAKE; GROWTH; GROWTH REGULATION; GUPPY; HAZARD ASSESSMENT; HETEROPNEUSTES FOSSILIS; LEPOMIS MACROCHIRUS; LEUCISCUS IDUS; LOCOMOTION; MEMBRANE DEPOLARIZATION; NONHUMAN; NOTROPIS CORNUTUS; OREOCHROMIS NILOTICUS; OXIDATIVE STRESS; PARALICHTHYS OLIVACEUS; PIMEPHALES PROMELAS; PREDICTION; RAINBOW TROUT; REVIEW; RHAMDIA QUELEN; RISK ASSESSMENT; SALVELINUS CONFLUENTUS; SEA BREAM; ADVERSE EFFECTS; ANIMAL; BIOLOGICAL MODEL; DRUG EFFECTS; EATING; ECOTOXICOLOGY; GROWTH, DEVELOPMENT AND AGING; HUMAN; POLLUTANT; PROCEDURES; SPECIES DIFFERENCE; TOXICITY TESTING; TRENDS;

ANIMALS; CADMIUM; EATING; ECOTOXICOLOGY; ENVIRONMENTAL POLLUTANTS; FISHES; HUMANS; LOCOMOTION; MODELS, BIOLOGICAL; PYRETHRINS; RISK ASSESSMENT; SEROTONIN UPTAKE INHIBITORS; SPECIES SPECIFICITY; TOXICITY TESTS, CHRONIC;

EID: 84912101578     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2014.10.006     Document Type: Review

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