The apparently very variable potency of the anti-depressant fluoxetine

Aquatic Toxicology

Volumn 151, Issue , 2014, Pages 57-60

  Sumpter, J P ^a   Donnachie, R L ^b   Johnson, A C ^b  

^a BRUNEL UNIVERSITY   (United Kingdom)

^b CENTRE FOR ECOLOGY AND HYDROLOGY   (United Kingdom)

Author keywords

Fish; Fluoxetine; Invertebrates; Variable potency

Indexed keywords

FLUOXETINE; SEROTONIN TRANSPORTER;

AQUATIC ENVIRONMENT; DRUG; ECOTOXICOLOGY; FISH; INVERTEBRATE;

ANIMAL BEHAVIOR; AQUATIC ENVIRONMENT; ARTICLE; BINDING AFFINITY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; ECOTOXICITY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL IMPACT; FISH; HUMAN; INVERTEBRATE; MEDICAL RESEARCH; NONHUMAN; PHYSICAL SENSITIVITY; PRIORITY JOURNAL; REPRODUCIBILITY; REPRODUCTIVE BEHAVIOR; RISK ASSESSMENT; STANDARDIZATION; WATER POLLUTION;

INVERTEBRATA;

FISH; FLUOXETINE; INVERTEBRATES; VARIABLE POTENCY;

ANIMALS; FISHES; FLUOXETINE; INVERTEBRATES; RESEARCH; SPECIES SPECIFICITY; TOXICOLOGY; WATER POLLUTANTS, CHEMICAL;

EID: 84899474392     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2013.12.010     Document Type: Article

References (38)

1. Airhart M.J., Lee D.H., Wilson T.D., Miller B.E., Miller M.N., Skalko R.G. Movement disorders and neurochemical changes in zebrafish larvae after bath exposure to fluoxetine (PROZAC). Neurotoxicology and Teratology 2007, 29:652-664.
2. Alonso S.G., Gatala M., Maroto R.R., Gil Gil J.L.R., de Miguel A.G., Varcarel Y. Pollution by psychoactive pharmaceuticals in the rivers of Madrid metropolitan area (Spain). Environment International 2010, 36:195-201.
3. Barry M.J. Effects of fluoxetine on swimming and behavioural responses of the Arabian killifish. Ecotoxicology 2013, 22:425-432.
4. Berninger J.P., Brooks B.W. Leveraging mammalian pharmaceutical toxicology and pharmacology data to predict chronic fish responses to pharmaceuticals. Toxicology Letters 2010, 193:69-78.
5. Bringolf R.B., Heltsley R.M., Newton T.J., Eads C.B., Fraley S.J., Shea D., Cope W.G. Environmental occurrence and reproductive effects of the pharmaceutical fluoxetine in native freshwater mussels. Environmental Toxicology and Chemistry 2010, 29:1311-1318.
6. Brooks B.W., Turner P.K., Stanley J.K., Weston J.J., Glidewell E.A., Foran C.M., Slattery M., La Point T.W., Huggett D.B. Waterborne and sediment toxicity of fluoxetine to select organisms. Chemosphere 2003, 52:135-142.
7. Di Poi C., Darmaillacq A.-S., Dickel L., Boulouard M., Bellanger C. Effects of perinatal exposure to waterborne fluoxetine on memory processing in the cuttlefish Sepia officinalis. Aquatic Toxicology 2013, 132-133:84-91.
8. Dzieweczynski T.L., Hebert O.L. Fluoxetine alters behavioural consistency and aggression and courtship in male Siamese fighting fish, Betta splendens. Physiology and Behaviour 2012, 107:92-97.
9. Egan R.J., Bergner C.L., Hart P.C., Cachat J.M., Canavello P.R., Elegante M.F., Elkhayat S.I., Bartels B.K., Tien A.K., Tien D.H., Mohnot S., Beeson E., Glasgow E., Amri H., Zukowska Z., Kalueff A.V. Understanding behavioural and physiological phenotypes of stress and anxiety in zebrafish. Behavioural Brain Research 2009, 205:38-44.
10. Fong P.P., Molnar N. Norfluoxetine induces spawning and parturition in estuarine and freshwater bivalves. Bulletin of Environmental Contamination and Toxicology 2008, 81:535-538.
11. Fong P.P., Molnar N. Antidepressants cause foot detachment from substrate in five species of marine snail. Marine Environmental Research 2013, 84:24-30.
12. Franzellitti S., Buratti S., Valbonesi P., Fabbri E. The mode of action (MOA) approach reveals interactive effects of environmental pharmaceuticals on Mytilis galloprovincialis. Aquatic Toxicology 2013, 140-141:249-256.
13. Gardner M., Comber S., Scrimshaw M.D., Cartmell E., Lester J., Ellor B. The significance of hazardous chemicals in wastewater treatment works effluents. Science of the Total Environment 2012, 437:363-372.
14. Guler Y., Ford A.T. Anti-depressants make amphipods see the light. Aquatic Toxicology 2010, 99:397-404.
15. Hoeger B., Köllner B., Dietrich D.R., Hitzfeld B. Water-borne diclofenac affects kidney and gill integrity and selected immune parameters in brown trout (Salmo trutta f. fario). Aquatic Toxicology 2005, 75:53-64.
16. Hugget D.B., Cook J.C., Ericson J.E., Williams R.T. Theoretical model for prioritising potential impacts of human pharmaceuticals to fish. Journal of Human and Ecological Risk Assessment 2003, 9:1789-1799.
17. Kohlert J.G., Mangan B.P., Kodra C., Drako L., Long E., Simpson H. Decreased aggressive and locomotor behaviours in Betta splendens after exposure to fluoxetine. Psychological Reports 2012, 110:51-62.
18. Kreke N., Dietrich D.R. Physiological endpoints for potential SSRI interactions in fish. Critical Reviews in Toxicology 2008, 37:215-247.
19. Lazzara R., Blázquez M., Porte C., Barata C. Low environmental levels of fluoxetine induce spawning and changes in endogenous estradiol levels in the zebra mussel Dreissena polymorpha. Aquatic Toxicology 2012, 106-107:123-130.
20. Mehinto A.C., Hill E., Tyler C.R. Uptake and biological effects of environmentally relevant concentrations of the nonsteroidal anti-inflammatory pharmaceutical diclofenac in rainbow trout (Oncorhynchus mykiss). Environmental Science & Technology 2010, 44:2176-2182.
21. Memmert U., Peither A., Burri R., Weber K., Schmidt T., Sumpter J.P., Hartmann A. Diclofenac: new data on chronic toxicity and bioconcentration in fish. Environmental Toxicology and Chemistry 2013, 32:442-452.
22. Mennigen J.A., Lado W.E., Zamora J.M., Duarte-Guterman P., Langloi V.S., Metcalfe C.D., Chang J.P., Moon T.W., Trudeau V.L. Waterborne fluoxetine disrupts the reproductive axis in sexually mature male goldfish, Carassius auratus. Aquatic Toxicology 2010, 100:264-354.
23. Menningen J.A., Sassine J., Trudeau V.L., Moon T.W. Waterborne fluoxetine distrupts feeding and energy metabolism in the goldfish Carassius auratus. Aquatic Toxicology 2010, 100:128-137.
24. Nakamura Y., Yamamoto H., Sekizawa J., Kondo T., Hirai N., Tatarazako N. The effects of pH on fluoxetine in Japanese Medaka (Oryzias latipes): acute toxicity in fish larvae and bioaccumulation in juvenile fish. Chemosphere 2008, 70:815-873.
25. Owen S.F., Huggett D.B., Hutchinson T.H., Hetheridge M.J., McCormack P., Kinter L.B., Ericson J.F., Constantine L.A., Sumpter J.P. The value of repeating studies and multiple controls: replicated 28-day growth studies of rainbow trout exposed to clofibric acid. Environmental Toxicology and Chemistry 2010, 29:2831-2839.
26. Pittman J.T., Ichikawa K.M. iPhone® applications as versatile video tracking tools to analyse behaviour in zebrafish (Danio rerio). Pharmacology, Biochemistry and Behaviour 2013, 106:137-142.
27. Rand-Weaver M., Margiotta-Casaluci L., Patel A., Panter G.H., Owen S.F., Sumpter J.P. The read-across hypothesis and environmental risk assessment of pharmaceuticals. Environmental Science & Technology 2013, 47:12297-12304.
28. Schultz M.M., Painter M.M., Bartell S.E., Logue A., Furlong E.T., Werner S.L., Schoenfuss H.L. Selective uptake and biological consequences of environmentally relevant antidepressant pharmaceutical exposures on male fathead minnows. Aquatic Toxicology 2011, 104:38-47.
29. Schwaiger J., Ferling H., Mallow U., Wintermayr H., Negele D.R. Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part 1: histopathological alternations and bioaccumulation in rainbow trout. Aquatic Toxicology 2004, 68:141-150.
30. Sumpter J.P., Margiotta-Casaluci L. Are some invertebrates exquisitely sensitive to the human pharmaceutical fluoxetine?. Aquatic Toxicology 2013, http://dx.doi.org/10.1016/j.aquatox.2013.11.021, in press.
31. Tatsumi M., Groshan K., Blakely R.D., Richelson E. Pharmacological profile of anti-depressants and related compounds at human monoamine transporters. European Journal of Pharmacology 1997, 340:249-258.
32. Triebskorn R., Casper H., Heyd A., Eikemper R., Köhler H.-R., Schwaiger J. Toxic effects of the non-steroidal, anti-inflammatory drug diclofenac. Part II. Cytological effects in liver, kidney, gills, and intestine of rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology 2004, 68:151-166.
33. Vanderberg L.N., Colborn T.hayes T.B., Heindel J.J., Jacobs D.R., Lee D.H., Shioda T., Soto A.M., Vom Saal F.S., Welshons W.V., Zoeller R.T., Myers J.P. Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose-responses. Endocrine Reviews 2012, 33:378-455.
34. Vystavna Y., Huneau F., Grgnenko V., Vergeles Y., Celle-Jeanton H., Tapie N., Budzinski H., Le Coustumer P. Pharmaceuticals in rivers of two regions with contrasted socio-economic conditions: occurrence, accumulation, and comparison for Ukraine and France. Water, Air, & Soil Pollution 2012, 223:2111-2124.
35. Wang Y., Takai R., Yoshioka H., Shirabe K. Characterisation and expression of serotonin transporter genes in Zebrafish. Tohoku Journal of Experimental Medicine 2006, 208:267-274.
36. Winder V.L., Pennington P.L., Hurd M.W., Wirlth E.F. Fluoxetine effects on Sheepshead minnow (Cyprinodon variegates) locomotor activity. Journal of Environmental Science and Health: Part B 2012, 47:51-58.
37. Winter M.J., Owen S.F., Murray-Smith R.J., Panter G.H., Hetheridge M.J., Kinter L.B. Using data from drug discovery and development to aid the aquatic environmental risk assessment of human pharmaceuticals: concepts, considerations, and challenges. Integrated Environmental Assessment and Management 2010, 6:38-51.
38. Wong R.Y., Oxendine S.E., Godwin J. Behavioural and neurogenomic transcriptome changes in wild-derived zebrafish with fluoxetine treatment. BMC Genomics 2013, 14:348.