Effects of the antidepressant venlafaxine on fish brain serotonin and predation behavior

Aquatic Toxicology

Volumn 148, Issue , 2014, Pages 130-138

  Bisesi, Joseph H ^a   Bridges, William ^a   Klaine, Stephen J ^a  

^a CLEMSON UNIVERSITY   (United States)

Author keywords

Antidepressants; Behavior; Fish; Hybrid striped bass; Monoamines; Neurotransmitters; Pharmaceuticals; Serotonin; Venlafaxine

Indexed keywords

BRAIN MONOAMINE; DOPAMINE; NORADRENALIN; SEROTONIN; VENLAFAXINE;

BEHAVIORAL RESPONSE; BRAIN; CONCENTRATION (COMPOSITION); CYPRINID; DRUG; EFFLUENT; POLLUTION EFFECT; POLLUTION EXPOSURE; PREDATION; WASTEWATER;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; FISH; MORONE CHRYSOPS; NONHUMAN; PIMEPHALES PROMELAS; PREDATION; PREY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEADY STATE; STRIPED BASS;

ANTIDEPRESSANTS; BEHAVIOR; FISH; HYBRID STRIPED BASS; MONOAMINES; NEUROTRANSMITTERS; PHARMACEUTICALS; SEROTONIN; VENLAFAXINE;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN CHEMISTRY; CYCLOHEXANOLS; CYPRINIDAE; DRUG STABILITY; PREDATORY BEHAVIOR; SEROTONIN; WATER; WATER POLLUTANTS, CHEMICAL;

EID: 84893399081     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2013.12.033     Document Type: Article

References (50)

1. Aldegunde M., Soengas J., Ruibal C., Andrés M. Effects of chronic exposure to (-HCH (lindane) on brain serotonergic and gabaergic systems, and serum cortisol and thyroxine levels of rainbow trout, Oncorhynchus mykiss. Fish Physiol. Biochem. 1999, 20:325-330.
2. Anderson C.R., Campbell G., O'Shea F., Payne M. The release of neuronal 5-HT from the intestine of a teleost fish, Platycephalus bassensis. J. Auton. Nerv. Syst. 1991, 33:239-246.
3. Bielski R.J., Ventura D., Chang C. A double-blind comparison of escitalopram and venlafaxine extended release in the treatment of major depressive disorder. J. Clin. Psychiatry 2004, 65:1190-1196.
4. Brooks B.W., Foran C.M., Richards S.M., Weston J., Turner P.K., Stanley J.K., Solomon K.R., Slattery M., La Point T.W. Aquatic ecotoxicology of fluoxetine. Toxicol. Lett. 2003, 142:169-183.
5. Bymaster F.P., Dreshfield-Ahmad L.J., Threlkeld P.G., Shaw J.L., Thompson L., Nelson D.L., Hemrick-Luecke S.K., Wong D.T. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology 2001, 25:871-880.
6. Clotfelter E.D., O'Hare E.P., McNitt M.M., Carpenter R.E., Summers C.H. Serotonin decreases aggression via 5-HT1A receptors in the fighting fish Betta splendens. Pharm. Biochem. Behav. 2007, 87:222-231.
7. Coppen A., Bailey J. Enhancement of the antidepressant action of fluoxetine by folic acid: a randomised, placebo controlled trial. J. Affect. Disord. 2000, 60:121-130.
8. De Pedro N., Pinillos M.L., Valenciano A.I., Alonso-Bedate M., Delgado M.J. Inhibitory effect of serotonin on feeding behavior in goldfish: involvement of CRF. Peptides 1998, 19:505-511.
9. Galus M., Kirischian N., Higgins S., Purdy J., Chow J., Rangaranjan S., Li H.M., Wilson J.Y.C. Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish. Aquat. Toxicol. 2013.
10. Gaworecki K.M. Changes in Brain Biochemistry and Feeding Behavior in Hybrid Striped Bass Exposed to Environmental Contaminants 2008, Clemson University, Clemson, SC, Dissertation.
11. Gaworecki K.M., Klaine S.J. Behavioral and biochemical responses of hybrid striped bass during and after fluoxetine exposure. Aquat. Toxicol. 2008, 88:207-213.
12. Gomez M.J., Petrovic M., Fernandez-Alba A.R., Barcelo D. Determination of pharmaceuticals of various therapeutic classes by solid-phase extraction and liquid chromatography-tandem mass spectrometry analysis in hospital effluent wastewaters. J. Chromatogr. A 2006, 1114:224-233.
13. Gonzalez Alonso S., Catala M., Romo Maroto R., Rodriguez Gil J.L., Gil de Miguel A., Valcarcel Y. Pollution by psychoactive pharmaceuticals in the Rivers of Madrid metropolitan area (Spain). Environ. Int. 2010, 36:195-201.
14. Gracia-Lor E., Sancho J.V., Hernandez F. Simultaneous determination of acidic, neutral and basic pharmaceuticals in urban wastewater by ultra high-pressure liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 2010, 1217:622-632.
15. Halford J., Harrold J., Lawton C., Blundell J. Serotonin (5-HT) drugs: effects on appetite expression and use for the treatment of obesity. Curr. Drug Targets 2005, 6:201-213.
16. Henry T.B., Black M.C. Acute and chronic toxicity of fluoxetine (selective serotonin reuptake inhibitor) in western mosquitofish. Arch. Environ. Contam. Toxicol. 2008, 54:325-330.
17. Herrera-Perez P., Servili A., Rendon M.C., Sanchez-Vazquez F.J., Falcon J., Munoz-Cueto J.A. The pineal complex of the European sea bass (Dicentrarchus labrax): I. Histological, immunohistochemical and qPCR study. J. Chem. Neuroanat. 2011, 41:170-180.
18. Ings J., George N., Peter M., Servos M., Vijayan M. Venlafaxine and atenolol disrupt epinephrine-stimulated glucose production in rainbow trout hepatocytes. Aquat. Toxicol. 2012, 106:48-55.
19. Kolpin D.W., Furlong E.T., Meyer M.T., Thurman E.M., Zaugg S.D., Barber L.B., Buxton H.T. Pharmaceuticals, hormones, and other organic wastewater contaminants in US streams, 1999-2000: a national reconnaissance. Environ. Sci. Technol. 2002, 36:1202-1211.
20. Kreke N., Dietrich D.R. Physiological endpoints for potential SSRI interactions in fish. Crit. Rev. Toxicol. 2008, 38:215-247.
21. Le Poul E., Boni C., Hanoun N., Laporte A.M., Laaris N., Chauveau J., Hamon M., Lanfumey L. Differential adaptation of brain 5-HT1A and 5-HT1B receptors and 5-HT transporter in rats treated chronically with fluoxetine. Neuropharmacology 2000, 39:110-122.
22. Lin L., Pivorun E. Hypothalamic monoamines and their metabolites in the deermouse, Peromyscus maniculatus, during daily torpor. J. Neural Transm. Gen. Sect. 1990, 79:11-18.
23. Lowry C.A., Moore F.L. Regulation of behavioral responses by corticotropin-releasing factor. Gen. Comp. Endocrinol. 2006, 146:19-27.
24. Medeiros L.R., Mager E.M., Grosell M., McDonald M.D. The serotonin subtype 1A receptor regulates cortisol secretion in the Gulf toadfish, Opsanus beta. Gen. Comp. Endocrinol. 2010, 168:377-387.
25. Mennigen J.A., Harris E.A., Chang J.P., Moon T.W., Trudeau V.L. Fluoxetine affects weight gain and expression of feeding peptides in the female goldfish brain. Regul. Pept. 2009, 155:99-104.
26. Mennigen J.A., Martyniuk C.J., Crump K., Xiong H., Zhao E., Popesku J., Anisman H., Cossins A.R., Xia X., Trudeau V.L. Effects of fluoxetine on the reproductive axis of female goldfish (Carassius auratus). Physiol. Genomics 2008, 35:273-282.
27. Mennigen J.A., Stroud P., Zamora J.M., Moon T.W., Trudeau V.L. Pharmaceuticals as neuroendocrine disruptors: lessons learned from fish on prozac. J. Toxicol. Environ. Health B 2011, 14:387-412.
28. Metcalfe C.D., Koenig B.G., Bennie D.T., Servos M., Ternes T.A., Hirsch R. Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants. Environ. Toxicol. Chem. 2003, 22:2872-2880.
29. Metcalfe C.D., Miao X.S., Koenig B.G., Struger J. Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada. Environ. Toxicol. Chem. 2003, 22:2881-2889.
30. Metcalfe C.D., Chu S., Judt C., Li H., Oakes K.D., Servos M.R., Andrews D.M. Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed. Environ. Toxicol. Chem. 2010, 29:79-89.
31. Morando M.B., Medeiros L.R., McDonald M.D. Fluoxetine treatment affects nitrogen waste excretion and osmoregulation in a marine teleost fish. Aquat. Toxicol. 2009, 93:253-260.
32. Overli O., Harris C.A., Winberg S. Short-term effects of fights for social dominance and the establishment of dominant-subordinate relationships on brain monoamines and cortisol in rainbow trout. Brain Behav. Evolut. 1999, 54:263-275.
33. Overli O., Winberg S., Damsgard B., Jobling M. Food intake and spontaneous swimming activity in Arctic char (Salvelinus alpinus): role of brain serotonergic activity and social interactions. Can. J. Zool. 1998, 76:1366-1370.
34. Owens M., Morgan W., Plott S., Nemeroff C. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J. Pharmacol. Exp. Ther. 1997, 283:1305-1322.
35. Painter M.M., Buerkley M.A., Julius M.L., Vajda A.M., Norris D.O., Barber L.B., Furlong E.T., Schultz M.M., Schoenfuss H.L. Antidepressants at environmentally relevant concentrations affect predator avoidance behavior of larval fathead minnows (Pimephales Promelas). Environ. Toxicol. Chem. 2009, 28:2677-2684.
36. Ruibal C., Soengas J.L., Aldegunde M. Brain serotonin and the control of food intake in rainbow trout (Oncorhynchus mykiss): effects of changes in plasma glucose levels. J. Comp. Phys. A 2002, 188:479-484.
37. Saligaut C., Salbert G., Bailhache T., Bennani S., Jego P. Serotonin and dopamine turnover in the female rainbow trout (Oncorhynchus mykiss) brain and pituitary: changes during the annual reproductive cycle. Gen. Comp. Endocrinol. 1992, 85:261-268.
38. Schafer W.R. How do antidepressants work? Prospects for genetic analysis of drug mechanisms. Cell 1999, 98:551-554.
39. Schultz M.M., Furlong E.T. Trace analysis of antidepressant pharmaceuticals and their select degradates in aquatic matrixes by LC/ESI/MS/MS. Anal. Chem. 2008, 80:1756-1762.
40. Schultz M.M., Furlong E.T., Kolpin D.W., Werner S.L., Schoenfuss H.L., Barber L.B., Blazer V.S., Norris D.O., Vajda A.M. Antidepressant pharmaceuticals in two US effluent-impacted streams: occurrence and fate in water and sediment, and selective uptake in fish neural tissue. Environ. Sci. Technol. 2010, 44:1918-1925.
41. Schultz M.M., Painter M.M., Bartell S.E., Logue A., Furlong E.T., Werner S.L., Schoenfuss H.L. Selective uptake and biological consequences of environmentally relevant antidepressant pharmaceutical exposures on male fathead minnows. Aquat. Toxicol. 2011, 104:38-47.
42. Sebert P., Barthelemy L., Caroff J. Serotonin levels in fish brain: effects of hydrostatic pressure and water temperature. Experientia 1985, 41:1429-1430.
43. Somoza G.M., Peter R.E. Effects of serotonin on gonadotropin and growth hormone release from in vitro perifused goldfish pituitary fragments. Gen. Comp. Endocrinol. 1991, 82:103-110.
44. Thomas M.A., Joshi P.P., Klaper R.D. Gene-class analysis of expression patterns induced by psychoactive pharmaceutical exposure in fathead minnow (Pimephales promelas) indicates induction of neuronal systems. Comp. Biochem. Physiol. C 2012, 155:109-120.
45. Tsai C., Jang T., Wang L. Effects of mercury on serotonin concentration in the brain of tilapia, Oreochromis mossambicus. Neurosci. Lett. 1995, 184:208-211.
46. Vasskog T., Anderssen T., Pedersen-Bjergaard S., Kallenborn R., Jensen E. Occurrence of selective serotonin reuptake inhibitors in sewage and receiving waters at Spitsbergen and in Norway. J. Chromatogr. A 2008, 1185:194-205.
47. Velarde E., Delgado M.J., Alonso-Gomez A.L. Serotonin-induced contraction in isolated intestine from a teleost fish (Carassius auratus): characterization and interactions with melatonin. Neurogastroent. Motil. 2010, 22:E364-E373.
48. Winberg S., Lepage O. Elevation of brain 5-HT activity, POMC expression, and plasma cortisol in socially subordinate rainbow trout. Am. J. Phys. Reg. Integ. Comp. Phys. 1998, 274:R645-R654.
49. Winberg S., Nilsson G.E. Roles of brain monoamine neurotransmitters in agonistic behavior and stress reactions, with particular reference to fish. Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. 1993, 106:597-614.
50. Winder V., Sapozhnikova Y., Pennington P., Wirth E. Effects of fluoxetine exposure on serotonin-related activity in the sheepshead minnow (Cyprinodon variegatus) using LC/MS/MS detection and quantitation. Comp. Biochem. Physiol. C Pharmacol. Toxicol. Endocrinol. 2009, 149:559-565.