Development of a multiparametric in vitro model of skin sensitization

Journal of Applied Toxicology

Volumn 35, Issue 1, 2015, Pages 48-58

  Guyard Nicodème, Muriel ^a,e   Gerault, Eloise ^a   Platteel, Marion ^b   Peschard, Olivier ^c   Veron, Wilfried ^a   Mondon, Philippe ^c   Pascal, Svinareff ^b,d   Feuilloley, Marc G J ^a,d  

^a UNIVERSITÉ DE ROUEN   (France)

^b Biogalenys SAS   (France)

^c Sederma   (France)

^d BioAdmetys SAS   (France)

^e FRENCH AGENCY FOR FOOD   (France)

Author keywords

Cosmetic compounds; in vitro models; Interleukin 18; MTT Test; Skin permeation; Skin sensitization; Xenobiotic haptenation

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BENZOIC ACID; BENZYL ALCOHOL; HUMAN SERUM ALBUMIN; VANILLIN; ALLERGEN; COSMETIC; HAPTEN; INTERLEUKIN 18; IRRITANT AGENT;

ARTICLE; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; COSMETIC INDUSTRY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; SCREENING TEST; SKIN IRRITATION; SKIN SENSITIVITY; SKIN SENSITIZATION; SOLUBILITY; VALIDITY; ANIMAL TESTING ALTERNATIVE; BIOSYNTHESIS; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; DERMATITIS, ALLERGIC CONTACT; DIFFUSION CHAMBER; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; MULTIVARIATE ANALYSIS; PATHOLOGY; PROCEDURES; SKIN; SKIN ABSORPTION; STATISTICAL MODEL; TOXICITY TESTING;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; CELL SURVIVAL; CELLS, CULTURED; COSMETICS; DERMATITIS, ALLERGIC CONTACT; DIFFUSION CHAMBERS, CULTURE; HAPTENS; HUMANS; IN VITRO TECHNIQUES; INTERLEUKIN-18; IRRITANTS; KERATINOCYTES; MODELS, STATISTICAL; MULTIVARIATE ANALYSIS; SKIN; SKIN ABSORPTION; TOXICITY TESTS, ACUTE;

EID: 84911998548     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2986     Document Type: Article

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