Analysis of interleukin-1α (IL-1α) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization

Toxicology in Vitro

Volumn 17, Issue 3, 2003, Pages 311-321

  Coquette, A ^a   Berna, N ^b   Vandenbosch, A ^a   Rosdy, M ^c   De Wever, B ^c   Poumay, Y ^b  

^a SGS Medisearch International NV   (Belgium)

^b UNIVERSITY OF NAMUR   (Belgium)

^c SkinEthic   (France)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 1 FLUORO 2,4 DINITROBENZENE; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; BENZALKONIUM CHLORIDE; BENZOIC ACID; CYTOKINE; DODECYL SULFATE SODIUM; INTERLEUKIN 1ALPHA; INTERLEUKIN 8; IRRITANT AGENT; MESSENGER RNA; NICKEL SULFATE; OXAZOLONE; TRINITROBENZENESULFONIC ACID;

ARTICLE; ASSAY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; EPIDERMIS; EXTRACELLULAR SPACE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SPACE; NORMAL HUMAN; PREDICTION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; SKIN IRRITATION; SKIN SENSITIZATION; UPREGULATION;

EID: 0037683581     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(03)00019-5     Document Type: Article

References (52)

1. Barker J.N.W.N., Mitra R.S., Griffiths C.E.M., Dixit V.M., Nickoloff B.J. Keratinocytes as initiators of inflammation. Lancet. 337:1991;211-214.
2. Basketter D.A., Reynolds F.S., York M. Predictive testing in contact dermatitis. irritant dermatitis Clinics in Dermatology. 15:1999;637-644.
3. Basketter D.A., Blaikie L., Dearman R.J., Kimber I., Ryan C.A., Gerberick G.F., Harvey P., Evans P., White I.R., Rycroft R.J.G. Use of the local lymph node assay for the estimation of relative contact allergenic potency. Contact Dermatitis. 42:2000;344-348.
4. Bell E., Parenteau N., Gay R., Nolte C., Kemp P., Ekstein B., Johnson E. The living skin equivalent. its manufacture, its organotypic properties and its response to irritants Toxicology In Vitro. 5:1991;591-596.
5. Bernard F.-X., Barrault C., Deguercy A., De Wever B., Rosdy M. Expression of type-1 5a-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic). a new model for screening skin-targeted androgen modulators International Journal of Cosmetic Sciences. 22:2000;397-407.
6. Bernard F.-X., Barrault C., Deguercy A., De Wever B., Rosdy M. Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis. Cell Biology and Toxicology. 16(6):2000;391-400.
7. Berardesca E., Distante F. Mechanisms of skin irritations. Current Problem in Dermatology. 23:1995;1-8.
8. Boyce S., Michel S., Reichert U., Shroot B., Schmidt R. Reconstructed skin from cultured human keratinocytes and fibroblasts on a collagen-glycosaminoglycan biopolymer substrate. Skin Pharmacology. 2:1990;136-143.
9. Buehler E.V. Delayed contact hypersensitivity in the guinea pig. Archives of Dermatology. 91:1965;171-177.
10. Chabot-Fletcher M., Breton J., Lee J., Young P., Griswold D.E. Interleukin-8 production is regulated by protein kinase C in human keratinocytes. Journal of Investigative Dermatology. 103(4):1994;509-515.
11. Coquette A., Berna N., Vandenbosch A., Rosdy M., Poumay Y. Differential expression and release of cytokines by an in vitro reconstructed human epidermis following exposure to skin irritant and sensitizing chemicals. Toxicology In Vitro. 13:1999;867-877.
12. Coquette A., Berna N., Poumay Y., Pittelkow M.R. The keratinocyte in cutaneous irritation and sensitisation. Kydonicus A.F., Wille J.J. Biochemical Modulation of Skin Reaction. 2000;125-143 CRC Press, New York.
13. Coquette A., Berna N., Vandenbosch A., Poumay Y. Specific enhanced release of interleukin-8 and interleukin-1α in reconstructed human epidermis in vitro after stimulation with different classes of skin irritants and contact sensitisers. Balls M., van Zeller A.M., Halder M.E. Progress in the Reduction, Refinement and Replacement of Animal Experimentation. 2000;653-664 Elsevier Science, Amsterdam, The Netherlands.
14. Corsini E., Marinovich M., Galli C.L. In vitro keratinocytes responses to chemical allergens. Bolletino Chimico Farmaceutico. 134:1995;569-573.
15. Corsini E., Bruccoleri A., Marinovich M., Galli C.L. Endogenous Interleukin-1-alpha is associated with skin irritation induced by tributyltin. Toxicology and Applied Pharmacology. 138(2):1996;268-274.
16. Corsini E., Galli C.L. Use of the in vitro reconstituted human epidermis, EPISKIN, to assess the molecular mechanisms of skin irritation and sensitisation. Van Zutphen L.F.M., Balls M. Animal Alternatives, Welfare and Ethics. 1997;575-582 Elsevier Science, Amsterdam, The Netherlands.
17. Coutant K.D., Ulrich P., Thomas H., Cordier A., Brugerolle de Fraissinette A. Early changes in murine epidermal cell phenotype by contact sensitizers. Toxicological Sciences. 48(1):1999;74-81.
18. Cumberbatch M., Dearman R.J., Kimber L. Constitutive and inducible expression of interleukin-6 by Langherhans cells and lymph node dendritic cells. Immunology. 87:1996;513-518.
19. De Brugerolle de Fraisinette A., Picarles V., Chibout S., Kolopp M., Medina J., Burtin P., Ebelin M.-E., Osborne S., Mayer F.K., Spake A., Rosdy M., De Wever B., Ettlin R.A., Cordier A. Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles. Cell Biology and Toxicology. 15(2):1999;121-135.
20. De Silva O., Basketter D.A., Barrat M.D., Corsini E., Cronin M.T.D., Das P.K. Alternative methods for skin sensitization testing. The report and recommendations of ECVAM workshop 19. ATLA. 24:1996;683-705.
21. Draize J.H., Woodward G., Calvery H.O. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. Journal of Pharmacology and Experimental Therapeutics. 82:1944;377-390.
22. Gay R., Swiderek M., Nelson D., Ernesti A. The living skin equivalent as a model in vitro for ranking the toxic potential of dermal irritants. Toxicology In Vitro. 6(4):1992;303-315.
23. Goebeler M., Trautmann A., Voss A., Bröcker E.B., Toksoy A., Gillitzer R. Differential and sequential expression of multiple chemokines during elicitation of allergic contact hypersensitivity. American Journal of Pathology. 158(2):2001;431-440.
24. Gysler A., Kleuser B., Sippl W., Lange K., Korting H.C., Höltje H.-D., Schäfer-Korting M. Skin penetration and metabolism of topical glucocorticoids in reconstructed epidermis and excised human skin. Pharmaceutical Research. 16(9):1999;1386-1391.
25. - dendritic cells and keratinocytes to characterize cellular reactions involved in allergic contact dermatitis. Journal of Cellular Biochemistry. 21(A):1995;11.
26. Kupper T.S., Groves R.W. The interleukin-1 axis and cutaneous inflammation. Journal of Investigative Dermatology. 105:1995;62-66.
27. Laugier J.-P., Shuster S., Rosdy M., Csóka A.B., Stern R., Maibach H.I. Topical hyaluronidase decreases hyaluronic acid and CD44 in human skin and in reconstituted human epidermis. evidence that hyaluronidase can permeate the stratum corneum British Journal of Dermatology. 142:2000;226-233.
28. Lisby S., Müller K.M., Jongeneel V., Saurat J.-H., Hauser C. Nickel and skin irritants up-regulate tumor necrosis factor α mRNA in keratinocytes by different but potentially synergistic mechanisms. International Immunology. 7(3):1995;343-352.
29. Mc Kenzie R.C., Snauders D.N. The role of keratinocytes cytokines in inflammation and immunity. Journal of Investigative Dermatology. 95:1990;105S-107S.
30. Magnusson B., Kligman A.M. Allergic Contact Dermatitis in the Guinea Pig. 1970;Charles C. Thomas, Springfield, IL.
31. Mohamadzadeh M., Müller M., Hultsch T., Enk A., Saloga J., Knop J. Enhanced expression of IL-8 in normal human keratinocytes and human keratinocyte cell line HaCat in vitro after stimulation with contact sensitizers, tolerogens and irritants. Experimental Dermatology. 3:1994;298-303.
32. Morhenn V.B., En-Yuh Chang, Rheins L.A. A noninvasive method for quantifying and distinguishing inflammatory skin reaction. Journal of the American Academy of Dermatology. 41(5):1999;687-692.
33. Müller-Decker K., Fürstenberger G., Marks F. Keratinocyte-derived proinflammatory key mediators and cell viability as in vitro parameters of skin irritancy. a possible alternative to the Draize skin irritation test Toxicology and Applied Pharmacology. 127:1994;99-108.
34. Paludan K., Thestrup-Pedersen K. Use of the polymerase chain reaction in quantification of interleukin 8 mRNA in minute epidermal samples. Journal of Investigative Dermatology. 99:1992;830-835.
35. Pastore S., Shivji G.M., Kondo S. Effects of contact sensitizers neomycin sulfate, benzocaine and 2,4-dinitrobenzene 1-sulfonate, sodium salt on viability, membrane integrity and IL-1 alpha mRNA expression of cultured normal human keratinocytes. Food and Chemical Toxicology. 33:1995;57-68.
36. Pineau N., Dossou K.G., De Silva O. Antigen presentation by murine epidermal cells in vitro. Rougier A., Goldberg A.M., Maibach H.I. In Vitro Skin Toxicology. Irritation, Phototoxicity, Sensitisation. 1994;325-331 Mary Ann Liebert, New York, USA.
37. Ponec M. In vitro cultured human skin cells as alternatives to animals for skin irritancy screening. International Journal of Cosmetology. 14:1992;245-264.
38. Ponec M. Reconstructed epidermis in vitro. an alternative to animal testing ATLA. 23:1995;97-110.
39. Ponec M., Kempenaar J. Use of human skin recombinants as an in vitro model for testing the irritation potential of cutaneous irritants. Skin Pharmacology. 8:1995;49-59.
40. Rambukkana A., Pistoor F.H.M., Bos J.D., Kapsenberg M.L., Das P.K. Effects of contact allergens on human Langerhans cells in skin organ culture. migration, modulation of cell surface molecules and early expression of IL-1ß protein Laboratory Investigations. 79:1996;422-436.
41. Régnier M., Asselineau D., Lenoir M.C. Human epidermis reconstructed on dermal substrates in vitro. an alternative to animals in skin pharmacology Skin Pharmacology. 3:1990;70-85.
42. Rosdy M., Clauss L.C. Terminal epidermal differentiation of human keratinocytes grown in chemically defined medium on inert filter substrates at the air-liquid interface. Journal of Investigative Dermatology. 95(4):1990;409-414.
43. Rosdy M., Pisani A., Ortonne J.P. Production of basement membrane components by a reconstructed epidermis cultured in the absence of serum and dermal factors. British Journal of Dermatology. 129:1993;227-234.
44. Rosdy M., Fartasch M., Ponec M. Structurally and biochemically normal permeability barrier of human epidermis reconstituted in chemically defined medium. Journal of Investigative Dermatology. 107(4):1996;664.
45. Schröder J.M. Cytokine network in the skin. Journal of Investigating Dermatology. 105:1995;20s-24s.
46. Srivasta B.I., Srivasta A., Srivasta M.D. Phenotype, genotype and cytokine production in acute leukemia involving progenitors of dendritic Langerhans cells. Leukocyte Research. 18:1994;499-511.
47. Tinois E., Tiollier J., Gaucherand M., Dumas H., Tardy M., Thivolet J. In vitro and post-transplantation differentiation of human keratinocytes grown on human type IV collagen film of a bilayered dermal substitute. Experimental Cell Research. 193:1991;310-331.
48. Van Och F.M., Slob W., de Jongh W.H., Vandebriel R.J., van Loveren H. A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employement of a regression method that includes determination of the uncertainty margins. Toxicology. 145(1):2000;49-59.
49. Wahlberg J.E. Clinical overview of irritant dermatitis. van der Valk P.G.M., Maibach H.I. The Irritant Contact Dermatitis Syndrome. 1996;1-6 CRC Press, Boca Raton, FL.
50. Wang A.M., Doyle M.V., Mark D.F. Quantitation of mRNA by the polymerase chain reaction. Proceedings of the National Academy of Sciences of the USA. 86:1989;9717-9721.
51. Williams I.R., Kupper T.S. Immunity at the surface. homeostatic mechanisms of the skin immune system Life Sciences. 58:1996;1485-1507.
52. Wilmer J.L., Burleson F.G., Kayama F., Kanno J., Luster M.I. Cytokine induction in human epidermal keratinocytes exposed to contact irritants and its relation to chemical-induced inflammation in mouse skin. Journal of Investigative Dermatology. 102(6):1994;915-922.