Prediction of the contact sensitizing potential of chemicals using analysis of gene expression changes in human THP-1 monocytes

Toxicology Letters

Volumn 199, Issue 1, 2010, Pages 51-59

  Arkusz, J ^a   StEogonekpnik, Maciej ^a   Sobala, Wojciech ^a   Dastych, Jarosław ^b  

^a NOFER INSTITUTE OF OCCUPATIONAL MEDICINE   (Poland)

^b INSTITUTE OF MEDICAL BIOLOGY   (Poland)

Author keywords

Gene expression; In vitro; Skin sensitizers; THP 1

Indexed keywords

HEME OXYGENASE 1; INTERLEUKIN 8; NUCLEAR PROTEIN; PROTEIN PAIMP1; UNCLASSIFIED DRUG; ALLERGEN; BIOLOGICAL MARKER; FORMAZAN; HMOX1 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; MESSENGER RNA; MTT FORMAZAN; PAIM I; PEPTIDE; TETRAZOLIUM; XENOBIOTIC AGENT;

ARTICLE; CELL LINE; CONTACT SENSITIZATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; ANIMAL TESTING ALTERNATIVE; CELL SURVIVAL; CLASSIFICATION; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MONOCYTE; PATHOLOGY; PREDICTIVE VALUE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXICITY;

ALLERGENS; ANIMAL TESTING ALTERNATIVES; BIOLOGICAL MARKERS; CELL LINE; CELL SURVIVAL; FORMAZANS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEME OXYGENASE-1; HUMANS; INTERLEUKIN-8; MONOCYTES; PEPTIDES; PREDICTIVE VALUE OF TESTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLIUM SALTS; XENOBIOTICS;

EID: 77957132598     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2010.08.005     Document Type: Article

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