Determining epidermal disposition kinetics for use in an integrated nonanimal approach to skin sensitization risk assessment

Toxicological Sciences

Volumn 119, Issue 2, 2011, Pages 308-318

  Davies, Michael ^a   Pendlington, Ruth U ^a   Page, Leanne ^b   Roper, Clive S ^b   Sanders, David J ^a   Bourner, Clare ^a   Pease, Camilla K ^a   MacKay, Cameron ^a  

^a UNILEVER RESEARCH   (United Kingdom)

^b In Vitro Sciences   (United Kingdom)

Author keywords

Area under the curve; In silico; In vitro; Mathematical modeling; Skin permeation; Skin sensitization

Indexed keywords

AREA UNDER THE CURVE; ARTICLE; CELL KINETICS; COMPARTMENT MODEL; CONTROLLED STUDY; EPIDERMIS CELL; HUMAN; HUMAN TISSUE; MATHEMATICAL MODEL; MAXIMUM PLASMA CONCENTRATION; RISK ASSESSMENT; SKIN PENETRATION; SKIN SENSITIZATION; STRATUM CORNEUM;

ANIMALIA;

EID: 78751681443     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfq326     Document Type: Article

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