-
1
-
-
0002908647
-
Crystalline lipoic acid A. Catalytic agent associated with pyruvate dehydrogenase
-
Reed LJ, Crystalline Lipoic Acid A. Catalytic Agent Associated with Pyruvate Dehydrogenase. Science 1951;114(2952): 93-4
-
(1951)
Science
, vol.114
, Issue.2952
, pp. 93-94
-
-
Reed, L.J.1
-
2
-
-
0035914303
-
A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexes
-
Reed LJ. A trail of research from lipoic acid to alpha-keto acid dehydrogenase complexes. J Biol Chem 2001;276(42):38329-36
-
(2001)
J Biol Chem
, vol.276
, Issue.42
, pp. 38329-38336
-
-
Reed, L.J.1
-
4
-
-
84887224886
-
A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease
-
Shinto L, Quinn J, Montine T, et al. A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease. J Alzheimers Dis 2014;38(1):111-20
-
(2014)
J Alzheimers Dis
, vol.38
, Issue.1
, pp. 111-120
-
-
Shinto, L.1
Quinn, J.2
Montine, T.3
-
6
-
-
0002741844
-
Effect of a-lipoic acid on vitamin C and vitamin e deficiencies
-
Rosenberg HR, Culik R. Effect of a-lipoic acid on vitamin C and vitamin E deficiencies. Arch Biochem Biophys 1959; 80(1):86-93
-
(1959)
Arch Biochem Biophys
, vol.80
, Issue.1
, pp. 86-93
-
-
Rosenberg, H.R.1
Culik, R.2
-
7
-
-
0029031443
-
Thioctic (lipoic) acid: A therapeutic metal-chelating antioxidant?
-
Ou P, Tritschler HJ, Wolff SP. Thioctic (lipoic) acid: a therapeutic metal-chelating antioxidant? Biochem Pharmacol 1995; 50(1):123-6
-
(1995)
Biochem Pharmacol
, vol.50
, Issue.1
, pp. 123-126
-
-
Ou, P.1
Tritschler, H.J.2
Wolff, S.P.3
-
8
-
-
0030696877
-
Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization
-
Han D, Handelman G, Marcocci L, et al. Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization. BioFactors 1997;6(3):321-38
-
(1997)
BioFactors
, vol.6
, Issue.3
, pp. 321-338
-
-
Han, D.1
Handelman, G.2
Marcocci, L.3
-
9
-
-
69949104384
-
Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
-
Shay KP, Moreau RF, Smith EJ, et al. Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochim Biophys Acta 2009; 1790(10):1149-60
-
(2009)
Biochim Biophys Acta
, vol.1790
, Issue.10
, pp. 1149-1160
-
-
Shay, K.P.1
Moreau, R.F.2
Smith, E.J.3
-
10
-
-
0000561914
-
A-Ketoglutaric Dehydrogenase VIII Isolation and some properties of a flavoprotein component
-
Searls RL, Sanadi DR. a-Ketoglutaric Dehydrogenase VIII. Isolation and some properties of a flavoprotein component. J Biol Chem 1960;235(8):2485-91
-
(1960)
J Biol Chem
, vol.235
, Issue.8
, pp. 2485-2491
-
-
Searls, R.L.1
Sanadi, D.R.2
-
11
-
-
0014139748
-
The standard redox potential of cysteine-cystine from the thiol-disulphide exchange reaction with glutathione and lipoic acid
-
Jocelyn PC. The standard redox potential of cysteine-cystine from the thiol-disulphide exchange reaction with glutathione and lipoic acid. Eur J Biochem 1967;2(3): 327-31
-
(1967)
Eur J Biochem
, vol.2
, Issue.3
, pp. 327-331
-
-
Jocelyn, P.C.1
-
12
-
-
0032571329
-
Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate
-
Prasad PD, Wang H, Kekuda R, et al. Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate. J Biol Chem 1998; 273(13):7501-6
-
(1998)
J Biol Chem
, vol.273
, Issue.13
, pp. 7501-7506
-
-
Prasad, P.D.1
Wang, H.2
Kekuda, R.3
-
13
-
-
34447336400
-
Transepithelial transport of alpha-lipoic acid across human intestinal Caco-2 cell monolayers
-
Takaishi N, Yoshida K, Satsu H, Shimizu M. Transepithelial transport of alpha-lipoic acid across human intestinal Caco-2 cell monolayers. J Agri Food Chem 2007;55(13):5253-9
-
(2007)
J Agri Food Chem
, vol.55
, Issue.13
, pp. 5253-5259
-
-
Takaishi, N.1
Yoshida, K.2
Satsu, H.3
Shimizu, M.4
-
14
-
-
0036628732
-
Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells
-
Jones W, Li X, Qu Z-C, et al. Uptake, recycling, and antioxidant actions of alpha-lipoic acid in endothelial cells. Free Radic Biol Med 2002;33(1):83-93
-
(2002)
Free Radic Biol Med
, vol.33
, Issue.1
, pp. 83-93
-
-
Jones, W.1
Li, X.2
Qu, Z.-C.3
-
15
-
-
33845713183
-
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias
-
Holmquist L, Stuchbury G, Berbaum K, et al. Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. Pharm Ther 2007;113(1):154-64
-
(2007)
Pharm Ther
, vol.113
, Issue.1
, pp. 154-164
-
-
Holmquist, L.1
Stuchbury, G.2
Berbaum, K.3
-
16
-
-
8644274038
-
R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase
-
Korotchkina LG, Sidhu S, Patel MS. R-lipoic acid inhibits mammalian pyruvate dehydrogenase kinase. Free Radic Res 2004; 38(10):1083-92
-
(2004)
Free Radic Res
, vol.38
, Issue.10
, pp. 1083-1092
-
-
Korotchkina, L.G.1
Sidhu, S.2
Patel, M.S.3
-
17
-
-
0036408866
-
Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species
-
Bunik VI, Sievers C. Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species. Eur J Biochem 2002;269(20):5004-15
-
(2002)
Eur J Biochem
, vol.269
, Issue.20
, pp. 5004-5015
-
-
Bunik, V.I.1
Sievers, C.2
-
18
-
-
0037352050
-
2-Oxo acid dehydrogenase complexes in redox regulation Role of the lipoate residues and thioredoxin
-
Bunik VI. 2-Oxo acid dehydrogenase complexes in redox regulation. Role of the lipoate residues and thioredoxin. Eur J Biochem 2003;270(6):1036-42
-
(2003)
Eur J Biochem
, vol.270
, Issue.6
, pp. 1036-1042
-
-
Bunik, V.I.1
-
19
-
-
37849043898
-
Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: Glutathionylation and protection of lipoic acid
-
Applegate MAB, Humphries KM, Szweda LI. Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid. Biochemistry 2008;47(1):473-8
-
(2008)
Biochemistry
, vol.47
, Issue.1
, pp. 473-478
-
-
Applegate, M.A.B.1
Humphries, K.M.2
Szweda, L.I.3
-
20
-
-
4544359913
-
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species
-
Starkov AA, Fiskum G, Chinopoulos C, et al. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci 2004;24(36): 7779-88
-
(2004)
J Neurosci
, vol.24
, Issue.36
, pp. 7779-7788
-
-
Starkov, A.A.1
Fiskum, G.2
Chinopoulos, C.3
-
21
-
-
4544226082
-
Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase
-
Tretter L, Adam-Vizi V. Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase. J Neurosci 2004;24(36): 7771-8
-
(2004)
J Neurosci
, vol.24
, Issue.36
, pp. 7771-7778
-
-
Tretter, L.1
Adam-Vizi, V.2
-
22
-
-
0024586535
-
Supramolecular organization of tricarboxylic acid cycle enzymes
-
Lyubarev AE, Kurganov BI. Supramolecular organization of tricarboxylic acid cycle enzymes. Bio Sys 1989;22(2):91-102
-
(1989)
Bio Sys
, vol.22
, Issue.2
, pp. 91-102
-
-
Lyubarev, A.E.1
Kurganov, B.I.2
-
23
-
-
78650103059
-
A-Ketoglutarate dehydrogenase: A mitochondrial redox sensor
-
Mclain AL, Szweda PA, Szweda LI. a-Ketoglutarate dehydrogenase: a mitochondrial redox sensor. Free Radic Res 2011;45(1):29-36
-
(2011)
Free Radic Res
, vol.45
, Issue.1
, pp. 29-36
-
-
McLain, A.L.1
Szweda, P.A.2
Szweda, L.I.3
-
24
-
-
0030768236
-
The pharmacology of the antioxidant lipoic acid
-
Biewenga GP, Haenen G, Bast A. The pharmacology of the antioxidant lipoic acid. Gen Pharmacol 1997;29(3):315-31
-
(1997)
Gen Pharmacol
, vol.29
, Issue.3
, pp. 315-331
-
-
Biewenga, G.P.1
Haenen, G.2
Bast, A.3
-
25
-
-
33847349283
-
Reactive oxygen species: A breath of life or death?
-
Fruehauf JP, Meyskens FL. Reactive oxygen species: a breath of life or death? Clin Cancer Res 2007;13(3):789-94
-
(2007)
Clin Cancer Res
, vol.13
, Issue.3
, pp. 789-794
-
-
Fruehauf, J.P.1
Meyskens, F.L.2
-
26
-
-
84911946560
-
Cancer metabolism: A nexus of matter, energy and reactive oxygen species
-
In: Kanner S, editor Springer; New York, NY, USA
-
Bingham P, Stuart SD, Zachar Z. Cancer metabolism: a nexus of matter, energy and reactive oxygen species. In: Kanner S, editor. Tumor metabolom targeting and drug development. Springer; New York, NY, USA: 2014. p. 7-27
-
(2014)
Tumor Metabolom Targeting and Drug Development
, pp. 7-27
-
-
Bingham, P.1
Stuart, S.D.2
Zachar, Z.3
-
27
-
-
0037362060
-
Alpha-lipoic acid induces p27(Kip)- dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines
-
Van de Mark K, Chen JS, Steliou K, et al. alpha-lipoic acid induces p27(Kip)- dependent cell cycle arrest in non-transformed cell lines and apoptosis in tumor cell lines. J Cell Physiol 2003;194(3): 325-40
-
(2003)
J Cell Physiol
, vol.194
, Issue.3
, pp. 325-340
-
-
Van De Mark, K.1
Chen, J.S.2
Steliou, K.3
-
28
-
-
84860721634
-
Alpha lipoic acid selectively inhibits proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells
-
Yamasaki M, Iwase M, Kawano K, et al. Alpha lipoic acid selectively inhibits proliferation and adhesion to fibronectin of v-H-ras-transformed 3Y1 cells. J Clin Biochem Nutr 2012;50(3):234-40
-
(2012)
J Clin Biochem Nutr
, vol.50
, Issue.3
, pp. 234-240
-
-
Yamasaki, M.1
Iwase, M.2
Kawano, K.3
-
29
-
-
43549122067
-
Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway
-
Shi DY, Liu HL, Stern JS, et al. Alpha-lipoic acid induces apoptosis in hepatoma cells via the PTEN/Akt pathway. FEBS Lett 2008;582(12):1667-71
-
(2008)
FEBS Lett
, vol.582
, Issue.12
, pp. 1667-1671
-
-
Shi, D.Y.1
Liu, H.L.2
Stern, J.S.3
-
30
-
-
77954906454
-
Alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells
-
Lee HS, Na MH, Kim WK. alpha-Lipoic acid reduces matrix metalloproteinase activity in MDA-MB-231 human breast cancer cells. Nutr Res 2010;30(6):403-9
-
(2010)
Nutr Res
, vol.30
, Issue.6
, pp. 403-409
-
-
Lee, H.S.1
Na, M.H.2
Kim, W.K.3
-
31
-
-
84867847230
-
Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line
-
Choi HJ, Kim TY, Ruiz-Llorente S, et al. Alpha-lipoic acid induces sodium iodide symporter expression in TPC-1 thyroid cancer cell line. Nucl Med Biol 2012;39(8): 1275-80
-
(2012)
Nucl Med Biol
, vol.39
, Issue.8
, pp. 1275-1280
-
-
Choi, H.J.1
Kim, T.Y.2
Ruiz-Llorente, S.3
-
32
-
-
18044392727
-
Alpha-lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O-2(-.)-generation
-
Wenzel U, Nickel A, Daniel H. Alpha-lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O-2(-.)-generation. Apoptosis 2005;10(2):359-68
-
(2005)
Apoptosis
, vol.10
, Issue.2
, pp. 359-368
-
-
Wenzel, U.1
Nickel, A.2
Daniel, H.3
-
33
-
-
33845726964
-
Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells
-
Simbula G, Columbano A, Ledda-Columbano GM, et al. Increased ROS generation and p53 activation in alpha-lipoic acid-induced apoptosis of hepatoma cells. Apoptosis 2007;12(1): 113-23
-
(2007)
Apoptosis
, vol.12
, Issue.1
, pp. 113-123
-
-
Simbula, G.1
Columbano, A.2
Ledda-Columbano, G.M.3
-
34
-
-
77953812337
-
The natural antioxidant alpha-lipoic acid induces p27(Kip1)-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells
-
Dozio E, Ruscica M, Passafaro L, et al. The natural antioxidant alpha-lipoic acid induces p27(Kip1)-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells. Eur J Pharmacol 2010;641(1):29-34
-
(2010)
Eur J Pharmacol
, vol.641
, Issue.1
, pp. 29-34
-
-
Dozio, E.1
Ruscica, M.2
Passafaro, L.3
-
35
-
-
33751180574
-
Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation
-
Moungjaroen J, Nimmannit U, Callery PS, et al. Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation. J Pharmacol Exp Ther 2006;319(3):1062-9
-
(2006)
J Pharmacol Exp Ther
, vol.319
, Issue.3
, pp. 1062-1069
-
-
Moungjaroen, J.1
Nimmannit, U.2
Callery, P.S.3
-
36
-
-
33748529374
-
Alpha-lipoic acid modulates ovarian surface epithelial cell growth
-
Vig-Varga E, Benson EA, Limbil TL, et al. Alpha-lipoic acid modulates ovarian surface epithelial cell growth. Gynecol Oncol 2006; 103(1):45-52
-
(2006)
Gynecol Oncol
, vol.103
, Issue.1
, pp. 45-52
-
-
Vig-Varga, E.1
Benson, E.A.2
Limbil, T.L.3
-
37
-
-
54049130826
-
Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells
-
Elangovan S, Hsieh TC. Control of cellular redox status and upregulation of quinone reductase NQO1 via Nrf2 activation by alpha-lipoic acid in human leukemia HL-60 cells. Int J Oncol 2008;33(4):833-8
-
(2008)
Int J Oncol
, vol.33
, Issue.4
, pp. 833-838
-
-
Elangovan, S.1
Hsieh, T.C.2
-
38
-
-
80052228524
-
Effects of Lipoic Acid, Caffeic Acid and a Synthesized Lipoyl-Caffeic Conjugate on Human Hepatoma Cell Lines
-
Guerriero E, Sorice A, Capone F, et al. Effects of Lipoic Acid, Caffeic Acid and a Synthesized Lipoyl-Caffeic Conjugate on Human Hepatoma Cell Lines. Molecules 2011;16(8):6365-77
-
(2011)
Molecules
, vol.16
, Issue.8
, pp. 6365-6377
-
-
Guerriero, E.1
Sorice, A.2
Capone, F.3
-
39
-
-
84870672248
-
Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo
-
Feuerecker BS, Pirsig C, Seidl M, et al. Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo. Cancer Biol Ther 2012;14:1425-35
-
(2012)
Cancer Biol Ther
, vol.14
, pp. 1425-1435
-
-
Feuerecker, B.S.1
Pirsig, C.2
Seidl, M.3
-
40
-
-
84862332140
-
Alpha-lipoic acid controls tumor growth and modulates hepatic redox state in ehrlich-ascites-carcinoma-bearing mice
-
Al Abdan M. Alpha-lipoic acid controls tumor growth and modulates hepatic redox state in ehrlich-ascites-carcinoma-bearing mice. Sci World J 2012;doi; 10.1100/2012/ 509838
-
(2012)
Sci World J
-
-
Al Abdan, M.1
-
41
-
-
77950841021
-
A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: Preliminary results
-
Schwartz LM, Abolhassani A, Guais E, et al. A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results. Oncol Rep 2010;23(5):1407-16
-
(2010)
Oncol Rep
, vol.23
, Issue.5
, pp. 1407-1416
-
-
Schwartz, L.M.1
Abolhassani, A.2
Guais, E.3
-
42
-
-
77949402381
-
Revisiting the ALA/N (alpha-lipoic acid/ low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: A report of 3 new cases
-
Berkson BM, Rubin DM, Berkson AJ. Revisiting the ALA/N (alpha-lipoic acid/ low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases. Integr Cancer Ther 2009;8(4):416-22
-
(2009)
Integr Cancer Ther
, vol.8
, Issue.4
, pp. 416-422
-
-
Berkson, B.M.1
Rubin, D.M.2
Berkson, A.J.3
-
43
-
-
84897062309
-
Metabolic Treatment of Cancer: Intermediate Results of a Prospective Case Series
-
Schwartz LL, Buhler P, Icard H, et al. Metabolic Treatment of Cancer: intermediate Results of a Prospective Case Series. Anticancer Res 2014;34(2):973-80
-
(2014)
Anticancer Res
, vol.34
, Issue.2
, pp. 973-980
-
-
Schwartz, L.L.1
Buhler, P.2
Icard, H.3
-
44
-
-
78650727185
-
Lipoic acid: Energy metabolism and redox regulation of transcription and cell signaling
-
Packer L, Cadenas E. Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. J Clin Biochem Nutr 2011;48(1):26-32
-
(2011)
J Clin Biochem Nutr
, vol.48
, Issue.1
, pp. 26-32
-
-
Packer, L.1
Cadenas, E.2
-
45
-
-
85006768050
-
The metabolism of tumors in the body
-
Warburg O, Wind F, Negelein E. The metabolism of tumors in the body. J Gen Physiol 1927;8(6):519-30
-
(1927)
J Gen Physiol
, vol.8
, Issue.6
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
47
-
-
85015483678
-
The pyruvate dehydrogenase complex in cancer: Implications for the transformed state and cancer chemotherapy
-
In: Canuto R, editor. Available from
-
Bingham PM, Zachar Z. The Pyruvate Dehydrogenase Complex in Cancer: Implications for the Transformed State and Cancer Chemotherapy. In: Canuto R, editor. Dehydrogenases. InTech; 2012.p. 41-62; Available from: http://dx.doi.org/ 10.5772/48582
-
(2012)
Dehydrogenases. InTech
, pp. 41-62
-
-
Bingham, P.M.1
Zachar, Z.2
-
48
-
-
84858604270
-
Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
-
Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 2012;21(3):297-308
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
49
-
-
0022891340
-
Tumors - Wounds that do not heal - Similarities between tumor stroma generation and wound-healing
-
Dvorak HF. Tumors - wounds that do not heal - similarities between tumor stroma generation and wound-healing. N Engl J Med 1986;315(26):1650-9
-
(1986)
N Engl J Med
, vol.315
, Issue.26
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
50
-
-
62549151252
-
Why are tumour blood vessels abnormal and why is it important to know?
-
Nagy JA, Chang SH, Dvorak AM, et al. Why are tumour blood vessels abnormal and why is it important to know? Br J Cancer 2009;100(6):865-9
-
(2009)
Br J Cancer
, vol.100
, Issue.6
, pp. 865-869
-
-
Nagy, J.A.1
Chang, S.H.2
Dvorak, A.M.3
-
51
-
-
84855434874
-
Caveolin-1 and cancer metabolism in the tumor microenvironment: Markers, models, and mechanisms
-
Sotgia F, Martinez-Outschoorn UE, Ubaldo E, et al. Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms. Ann Rev Pathol 2012;7(7): 423-67
-
(2012)
Ann Rev Pathol
, vol.7
, Issue.7
, pp. 423-467
-
-
Sotgia, F.1
Martinez-Outschoorn, U.E.2
Ubaldo, E.3
-
52
-
-
84055225365
-
Warburg meets autophagy: Cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis
-
Pavlides S, Vera I, Gandara R, et al. Warburg meets autophagy: cancer-associated fibroblasts accelerate tumor growth and metastasis via oxidative stress, mitophagy, and aerobic glycolysis. Antioxid Redox Signal 2012;16(11):1264-84
-
(2012)
Antioxid Redox Signal
, vol.16
, Issue.11
, pp. 1264-1284
-
-
Pavlides, S.1
Vera, I.2
Gandara, R.3
-
53
-
-
84877150506
-
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer
-
Curry JM, Tuluc M, Whitaker-Menezes D, et al. Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer. Cell Cycle 2013;12(9):1371-84
-
(2013)
Cell Cycle
, vol.12
, Issue.9
, pp. 1371-1384
-
-
Curry, J.M.1
Tuluc, M.2
Whitaker-Menezes, D.3
-
54
-
-
84897544161
-
Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth
-
Martinez-Outschoorn UE, Lisanti MP, Sotgia F. Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth. Semin Cancer Biol 2014;2014:25:47-60
-
(2014)
Semin Cancer Biol
, vol.2014
, Issue.25
, pp. 47-60
-
-
Martinez-Outschoorn, U.E.1
Lisanti, M.P.2
Sotgia, F.3
-
55
-
-
0346158376
-
Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation
-
Holness MJ, Sugden MC. Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation. Biochem Soc Trans 2003;31(6):1143-51
-
(2003)
Biochem Soc Trans
, vol.31
, Issue.6
, pp. 1143-1151
-
-
Holness, M.J.1
Sugden, M.C.2
-
56
-
-
80052845698
-
Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer
-
Lu CW, Lin SC, Chien CW, et al. Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer. Am J Pathol 2011;179(3):1405-14
-
(2011)
Am J Pathol
, vol.179
, Issue.3
, pp. 1405-1414
-
-
Lu, C.W.1
Lin, S.C.2
Chien, C.W.3
-
57
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, et al. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006;3(3):177-85
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
-
58
-
-
33644622570
-
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
-
Papandreou I, Cairns RA, Fontana L, et al. HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption. Cell Metab 2006;3(3): 187-97
-
(2006)
Cell Metab
, vol.3
, Issue.3
, pp. 187-197
-
-
Papandreou, I.1
Cairns, R.A.2
Fontana, L.3
-
59
-
-
84910095664
-
A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process
-
Available from
-
Stuart SD, Schauble A, Gupta S, et al. A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process. Cancer Metabol 2014.2:4. Available from: www. cancerandmetabolism.com/content/2/1/4
-
(2014)
Cancer Metabol
, vol.2
, pp. 4
-
-
Stuart, S.D.1
Schauble, A.2
Gupta, S.3
-
60
-
-
80755133485
-
Non-redox-active lipoatederivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
-
Zachar Z, Marecek J, Maturo C, et al. Non-redox-active lipoatederivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo. J Mol Med 2011;89(11):1137-48
-
(2011)
J Mol Med
, vol.89
, Issue.11
, pp. 1137-1148
-
-
Zachar, Z.1
Marecek, J.2
Maturo, C.3
-
61
-
-
84910088129
-
A phase i study of the first-in-class anti-mitochondrial metabolism agent, CPI-613, in patients with advanced hematologic malignancies
-
pii: clincanres.1019. PMID: 25165100. [Epub ahead of print]
-
Pardee TS, Lee K, Luddy J, et al. A phase I study of the first-in-class anti-mitochondrial metabolism agent, CPI-613, in patients with advanced hematologic malignancies. Clin Cancer Res 2014;pii: clincanres.1019. PMID: 25165100. [Epub ahead of print]
-
(2014)
Clin Cancer Res
-
-
Pardee, T.S.1
Lee, K.2
Luddy, J.3
|