Sulforaphane inhibits TNF-α-induced adhesion molecule expression through the rho A/ROCK/NF-κB signaling pathway

Journal of Medicinal Food

Volumn 17, Issue 10, 2014, Pages 1095-1102

  Hung, Chi Nan ^a   Huang, Hui Pei ^b,c   Wang, Chau Jong ^b,c   Liu, Kai Li ^b   Lii, Chong Kuei ^d,e  

^a MINGDAO UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

^e ASIA UNIVERSITY   (Taiwan)

Author keywords

atherosclerosis; proinflammation; Rho A; sulforaphane; tumor necrosis factor

Indexed keywords

CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SULFORAPHANE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; ISOTHIOCYANIC ACID DERIVATIVE; SULFORAFAN;

ARTICLE; BINDING AFFINITY; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; DNA BINDING; DOWN REGULATION; DRUG BINDING SITE; DRUG CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MTT ASSAY; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL LINE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM;

CELL LINE; DOWN-REGULATION; ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; ISOTHIOCYANATES; NF-KAPPA B; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84911886716     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2013.2901     Document Type: Article

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