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Volumn 213, Issue 1, 2010, Pages 122-128

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

Author keywords

Atherosclerosis; Endothelial lipase; High density lipoprotein; Nuclear factor (NF) B; Sulforaphane

Indexed keywords

CYTOKINE; ENDOTHELIAL LIPASE; HIGH DENSITY LIPOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; RNA; SULFORAPHANE; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 77958488608     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2010.07.015     Document Type: Article
Times cited : (34)

References (31)
  • 1
    • 0024449985 scopus 로고
    • High-density lipoprotein-the clinical implications of recent studies
    • Gordon D.J., Rifkind B.M. High-density lipoprotein-the clinical implications of recent studies. N Engl J Med 1989, 321:1311-1316.
    • (1989) N Engl J Med , vol.321 , pp. 1311-1316
    • Gordon, D.J.1    Rifkind, B.M.2
  • 2
    • 33845320131 scopus 로고    scopus 로고
    • Molecular regulation of HDL metabolism and function: implications for novel therapies
    • Rader D.J. Molecular regulation of HDL metabolism and function: implications for novel therapies. J Clin Invest 2006, 116:3090-3100.
    • (2006) J Clin Invest , vol.116 , pp. 3090-3100
    • Rader, D.J.1
  • 3
    • 0032901331 scopus 로고    scopus 로고
    • A novel endothelial-derived lipase that modulates HDL metabolism
    • Jaye M., Lynch K.J., Krawiec J., et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 1999, 21:424-428.
    • (1999) Nat Genet , vol.21 , pp. 424-428
    • Jaye, M.1    Lynch, K.J.2    Krawiec, J.3
  • 4
    • 0035988350 scopus 로고    scopus 로고
    • Characterization of the lipolytic activity of endothelial lipase
    • McCoy M.G., Sun G.S., Marchadier D., et al. Characterization of the lipolytic activity of endothelial lipase. J Lipid Res 2002, 43:921-929.
    • (2002) J Lipid Res , vol.43 , pp. 921-929
    • McCoy, M.G.1    Sun, G.S.2    Marchadier, D.3
  • 5
    • 0037314398 scopus 로고    scopus 로고
    • Endothelial lipase is a major determinant of HDL level
    • Ishida T., Choi S., Kundu R.K., et al. Endothelial lipase is a major determinant of HDL level. J Clin Invest 2003, 111:347-355.
    • (2003) J Clin Invest , vol.111 , pp. 347-355
    • Ishida, T.1    Choi, S.2    Kundu, R.K.3
  • 6
    • 0037316555 scopus 로고    scopus 로고
    • Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo
    • Jin W., Millar J.S., Broedl U., et al. Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo. J Clin Invest 2003, 111:357-362.
    • (2003) J Clin Invest , vol.111 , pp. 357-362
    • Jin, W.1    Millar, J.S.2    Broedl, U.3
  • 7
    • 0344406740 scopus 로고    scopus 로고
    • Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism
    • Ma K., Cilingiroglu M., Otvos J.D., et al. Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc Natl Acad Sci U S A 2003, 100:2748-2753.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2748-2753
    • Ma, K.1    Cilingiroglu, M.2    Otvos, J.D.3
  • 8
    • 0037056085 scopus 로고    scopus 로고
    • Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol
    • deLemos A.S., Wolfe M.L., Long C.J., et al. Identification of genetic variants in endothelial lipase in persons with elevated high-density lipoprotein cholesterol. Circulation 2002, 106:1321-1326.
    • (2002) Circulation , vol.106 , pp. 1321-1326
    • deLemos, A.S.1    Wolfe, M.L.2    Long, C.J.3
  • 9
    • 1242292260 scopus 로고    scopus 로고
    • Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels
    • Mank-Seymour A.R., Durham K.L., Thompson J.F., et al. Association between single-nucleotide polymorphisms in the endothelial lipase (LIPG) gene and high-density lipoprotein cholesterol levels. Biochim Biophys Acta 2004, 1636:40-46.
    • (2004) Biochim Biophys Acta , vol.1636 , pp. 40-46
    • Mank-Seymour, A.R.1    Durham, K.L.2    Thompson, J.F.3
  • 10
    • 65249186429 scopus 로고    scopus 로고
    • Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans
    • Edmondson A.C., Brown R.J., Kathiresan S., et al. Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest 2009, 119:1042-1050.
    • (2009) J Clin Invest , vol.119 , pp. 1042-1050
    • Edmondson, A.C.1    Brown, R.J.2    Kathiresan, S.3
  • 11
    • 0034720464 scopus 로고    scopus 로고
    • Regulated expression of endothelial cell-derived lipase
    • Hirata K., Ishida T., Matsushita H., et al. Regulated expression of endothelial cell-derived lipase. Biochem Biophys Res Commun 2000, 272:90-93.
    • (2000) Biochem Biophys Res Commun , vol.272 , pp. 90-93
    • Hirata, K.1    Ishida, T.2    Matsushita, H.3
  • 12
    • 40149083940 scopus 로고    scopus 로고
    • Endothelial lipase is increased in vivo by inflammation in humans
    • Badellino K.O., Wolfe M.L., Reilly M.P., et al. Endothelial lipase is increased in vivo by inflammation in humans. Circulation 2008, 117:678-685.
    • (2008) Circulation , vol.117 , pp. 678-685
    • Badellino, K.O.1    Wolfe, M.L.2    Reilly, M.P.3
  • 13
    • 0037418915 scopus 로고    scopus 로고
    • Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase
    • Jin W., Sun G.S., Marchadier D., et al. Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase. Circ Res 2003, 92:644-650.
    • (2003) Circ Res , vol.92 , pp. 644-650
    • Jin, W.1    Sun, G.S.2    Marchadier, D.3
  • 14
    • 24944473034 scopus 로고    scopus 로고
    • NF-kappaB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program
    • Kempe S., Kestler H., Lasar A., et al. NF-kappaB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program. Nucleic Acids Res 2005, 33:5308-5319.
    • (2005) Nucleic Acids Res , vol.33 , pp. 5308-5319
    • Kempe, S.1    Kestler, H.2    Lasar, A.3
  • 15
    • 34948862909 scopus 로고    scopus 로고
    • Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages
    • Qiu G., Hill J.S. Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages. J Lipid Res 2007, 48:2112-2122.
    • (2007) J Lipid Res , vol.48 , pp. 2112-2122
    • Qiu, G.1    Hill, J.S.2
  • 16
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q., Verma I.M. NF-kappaB regulation in the immune system. Nat Rev Immunol 2002, 2:725-734.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 17
    • 33645472584 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention
    • Bertl E., Bartsch H., Gerhauser C. Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention. Mol Cancer Ther 2006, 5:575-585.
    • (2006) Mol Cancer Ther , vol.5 , pp. 575-585
    • Bertl, E.1    Bartsch, H.2    Gerhauser, C.3
  • 18
    • 51249112155 scopus 로고    scopus 로고
    • The dietary histone deacetylase inhibitor sulforaphane induces human beta-defensin-2 in intestinal epithelial cells
    • Schwab M., Reynders V., Loitsch S., et al. The dietary histone deacetylase inhibitor sulforaphane induces human beta-defensin-2 in intestinal epithelial cells. Immunology 2008, 125:241-251.
    • (2008) Immunology , vol.125 , pp. 241-251
    • Schwab, M.1    Reynders, V.2    Loitsch, S.3
  • 19
    • 34447561905 scopus 로고    scopus 로고
    • Immunomodulatory activity of sulforaphane, a naturally occurring isothiocyanate from broccoli (Brassica oleracea)
    • Thejass P., Kuttan G. Immunomodulatory activity of sulforaphane, a naturally occurring isothiocyanate from broccoli (Brassica oleracea). Phytomedicine 2007, 14:538-545.
    • (2007) Phytomedicine , vol.14 , pp. 538-545
    • Thejass, P.1    Kuttan, G.2
  • 20
    • 0035943597 scopus 로고    scopus 로고
    • Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms
    • Heiss E., Herhaus C., Klimo K., et al. Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms. J Biol Chem 2001, 276:32008-32015.
    • (2001) J Biol Chem , vol.276 , pp. 32008-32015
    • Heiss, E.1    Herhaus, C.2    Klimo, K.3
  • 21
    • 22744440329 scopus 로고    scopus 로고
    • Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells
    • Xu C., Shen G., Chen C., et al. Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells. Oncogene 2005, 24:4486-4495.
    • (2005) Oncogene , vol.24 , pp. 4486-4495
    • Xu, C.1    Shen, G.2    Chen, C.3
  • 22
    • 33646237345 scopus 로고    scopus 로고
    • Stable RNA interference: comparison of U6 and H1 promoters in endothelial cells and in mouse brain
    • Mäkinen P.I., Koponen J.K., Kärkkäinen A.M., et al. Stable RNA interference: comparison of U6 and H1 promoters in endothelial cells and in mouse brain. J Gene Med 2006, 8:433-441.
    • (2006) J Gene Med , vol.8 , pp. 433-441
    • Mäkinen, P.I.1    Koponen, J.K.2    Kärkkäinen, A.M.3
  • 23
    • 46249097429 scopus 로고    scopus 로고
    • Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells
    • Kivela A.M., Kansanen E., Jyrkkanen H.K., et al. Enterolactone induces heme oxygenase-1 expression through nuclear factor-E2-related factor 2 activation in endothelial cells. J Nutr 2008, 138:1263-1268.
    • (2008) J Nutr , vol.138 , pp. 1263-1268
    • Kivela, A.M.1    Kansanen, E.2    Jyrkkanen, H.K.3
  • 24
    • 0029992609 scopus 로고    scopus 로고
    • Suppression of TNF-alpha-induced apoptosis by NF-kappaB
    • Van Antwerp D.J., Martin S.J., Kafri T., et al. Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science 1996, 274:787-789.
    • (1996) Science , vol.274 , pp. 787-789
    • Van Antwerp, D.J.1    Martin, S.J.2    Kafri, T.3
  • 25
    • 2442584612 scopus 로고    scopus 로고
    • CRE recombinase-inducible RNA interference mediated by lentiviral vectors
    • Tiscornia G., Tergaonkar V., Galimi F., et al. CRE recombinase-inducible RNA interference mediated by lentiviral vectors. Proc Natl Acad Sci U S A 2004, 101:7347-7351.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 7347-7351
    • Tiscornia, G.1    Tergaonkar, V.2    Galimi, F.3
  • 26
    • 59249103720 scopus 로고    scopus 로고
    • Oral sulforaphane increases phase II antioxidant enzymes in the human upper airway
    • Riedl M.A., Saxon A., Diaz-Sanchez D. Oral sulforaphane increases phase II antioxidant enzymes in the human upper airway. Clin Immunol 2009, 130:244-251.
    • (2009) Clin Immunol , vol.130 , pp. 244-251
    • Riedl, M.A.1    Saxon, A.2    Diaz-Sanchez, D.3
  • 27
    • 3042688047 scopus 로고    scopus 로고
    • In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat
    • Hu R., Hebbar V., Kim B.R., et al. In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate sulforaphane in the rat. J Pharmacol Exp Ther 2004, 310:263-271.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 263-271
    • Hu, R.1    Hebbar, V.2    Kim, B.R.3
  • 28
    • 3242689803 scopus 로고    scopus 로고
    • Endothelial lipase: a modulator of lipoprotein metabolism upregulated by inflammation
    • Broedl U.C., Jin W., Rader D.J. Endothelial lipase: a modulator of lipoprotein metabolism upregulated by inflammation. Trends Cardiovasc Med 2004, 14:202-206.
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 202-206
    • Broedl, U.C.1    Jin, W.2    Rader, D.J.3
  • 29
    • 47749136267 scopus 로고    scopus 로고
    • IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver
    • Luedde T., Heinrichsdorff J., de Lorenzi R., et al. IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver. Proc Natl Acad Sci U S A 2008, 105:9733-9738.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9733-9738
    • Luedde, T.1    Heinrichsdorff, J.2    de Lorenzi, R.3
  • 30
    • 0028168798 scopus 로고
    • Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression
    • Schindler U., Baichwal V.R. Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression. Mol Cell Biol 1994, 14:5820-5831.
    • (1994) Mol Cell Biol , vol.14 , pp. 5820-5831
    • Schindler, U.1    Baichwal, V.R.2
  • 31
    • 38349063001 scopus 로고    scopus 로고
    • Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-kappaB is dependent upon glutathione depletion in endothelial cells
    • Liu Y.C., Hsieh C.W., Weng Y.C., et al. Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-kappaB is dependent upon glutathione depletion in endothelial cells. Vasc Pharmacol 2008, 48:54-61.
    • (2008) Vasc Pharmacol , vol.48 , pp. 54-61
    • Liu, Y.C.1    Hsieh, C.W.2    Weng, Y.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.