Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-κB is dependent upon glutathione depletion in endothelial cells

Vascular Pharmacology

Volumn 48, Issue 1, 2008, Pages 54-61

  Liu, Yen Chin ^a   Hsieh, Chia Wen ^a   Weng, Yu Chun ^a   Chuang, Shu Hui ^a   Hsieh, Cheng Yuan ^a   Wung, Being Sun ^a  

^a NATIONAL CHIAYI UNIVERSITY   (Taiwan)

Author keywords

Glutathione; ICAM 1; LPS; NF B; Sulforaphane

Indexed keywords

GLUTATHIONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; SULFORAPHANE; SYNAPTOTAGMIN I;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME DEGRADATION; GENE EXPRESSION; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; AORTA; BLOTTING, WESTERN; CATTLE; CELL ADHESION; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GLUTATHIONE; I-KAPPA B PROTEINS; INTERCELLULAR ADHESION MOLECULE-1; LIPOPOLYSACCHARIDES; LUCIFERASES; MONOCYTES; NF-KAPPA B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SULFHYDRYL COMPOUNDS; THIOCYANATES; TIME FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 38349063001     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2007.11.006     Document Type: Article

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