Effects of Diet and Exercise on Obesity-Related Vascular Dysfunction in Children

Circulation

Volumn 109, Issue 16, 2004, Pages 1981-1986

  Woo, Kam S ^a   Chook, Ping ^a   Yu, Chung W ^a   Sung, Rita Y T ^a   Qiao, Mu ^a   Leung, Sophie S F ^a   Lam, Christopher W K ^a   Metreweli, Con ^a   Celermajer, David S ^b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

Author keywords

Atherosclerosis; Endothelium; Exercise; Lifestyle; Obesity

Indexed keywords

ARTERY ENDOTHELIUM; ARTERY INTIMA PROLIFERATION; ARTICLE; ATHEROSCLEROSIS; BEHAVIOR MODIFICATION; BEHAVIOR THERAPY; BODY MASS; CAROTID ARTERY; CHILDHOOD DISEASE; DIET; EXERCISE; FEMALE; HEALTH PROGRAM; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; SCHOOL CHILD; TRAINING;

ARTERIOSCLEROSIS; CAROTID ARTERY, COMMON; CHILD; COMBINED MODALITY THERAPY; ENDOTHELIUM, VASCULAR; EXERCISE THERAPY; FEMALE; HUMANS; MALE; OBESITY; VASODILATION;

EID: 2142767317     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000126599.47470.BE     Document Type: Article

References (18)

1. Kopelman PG. Obesity as a medical problem. Nature. 2000;404: 635-643.
2. Reilly JJ, Dorosty AR, Emmett PM. Prevalence of overweight and obesity in British children: cohort study. Br Med J. 1999;319:1039.
3. Berenson GS, Srinvasan SR, Bao W, et al, for the Bogalusa Heart Study. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. N Engl J Med. 1998;338:1650-1656.
4. Tounian P, Aggoun Y, Dubern B, et al. Presence of increased stiffness of the common carotid artery and endothelial dysfunction in severely obese children: a prospective study. Lancet. 2001;358:1400-1404.
5. Woo KS, Chook P, Yu CW, et al. Overweight in children is associated with arterial endothelial dysfunction and intima-media thickening. Int J Obesity. In press.
6. Ogden CL, Kuczmarski RJ, Flegal KM, et al. Centers for Disease Control and Prevention 2000 growth charts for the United States: improvements to the 1977 National Center for Health Statistics version. Pediatrics. 2002;109:45-60.
7. Woo KS, Chook P, Lolin YI, et al. Folic acid improves arterial endothelial function in adults with hyperhomocystinemia. J Am Coll Cardiol. 1999;34:2002-2006.
8. Raitakari OT, Celermajer DS. Testing for endothelial dysfunction. Ann Med. 2000;32:293-304.
9. Woo KS, Chook P, Raitakari OT, et al. Westernization of Chinese adults and increased subclinical atherosclerosis. Arterioscler Thromb Vasc Biol. 1999;19:2487-2493.
10. Sorensen KE, Celermajer DS, Spiegelhalter DJ, et al. Non-invasive measurement of human endothelium dependent arterial responses: accuracy and reproducibility. Br Heart J. 1995;74:247-53.
11. Adams MR, Nakagomi A, Keech A, et al. Carotid intima-media thickness is only weakly correlated with the extent and severity of coronary artery disease. Circulation. 1995;92:2127-2134.
12. O'Leary DH, Polak JF, Kronmai RA, et al. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med. 1999;340:14-22.
13. Hochberg Y. A sharper Bonferroni procedure for multiple tests of significance. Biometrika. 1988;75:800-802.
14. Kingwell BA, Sherrard B, Jennings GL, et al. Four weeks of cycle training increases basal production of nitric oxide from the forearm. Am J Physiol. 1997;272:H1070-H1077.
15. Hambrecht R, Wolf A, Gielen S, et al. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med. 2000;342:454-460.
16. Yudkin JS, Stehouwer CDA, Emeis JJ, et al. C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol. 1999;19:972-978.
17. Martorell R, Kettel Khan L, Hughes ML, et al. Overweight and obesity in preschool children from developing countries. Int J Obes Relat Metab Disord. 2000;24:959-967.
18. Connolly HM, Crary JL, McGoon MD, et al. Valvular heart disease associated with fenfluramine-phentermine. N Engl J Med. 1997;337:581-588.