Using engineered endonucleases to create knockout and knockin zebrafish models

Methods in Molecular Biology

Volumn 1239, Issue , 2015, Pages 291-306

  Bedell, Victoria M ^a   Ekker, Stephen C ^a  

^a MAYO GRADUATE SCHOOL   (United States)

Author keywords

Genome engineering; HDR; Homology directed repair; TALEN; Zebrafish

Indexed keywords

ENDONUCLEASE; GENOMIC DNA; MESSENGER RNA; RESTRICTION ENDONUCLEASE; SINGLE STRANDED DNA; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; ZINC FINGER NUCLEASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; CRISPR CAS SYSTEM; EMBRYO; ENZYME ANALYSIS; ENZYME ENGINEERING; ENZYME PURIFICATION; GENE INACTIVATION; GENE INSERTION SEQUENCE; GENE LOCUS; GENE TARGETING; GERM LINE; GERMLINE MUTATION; NONHUMAN; TRANSGENIC ZEBRAFISH; ANIMAL; ANIMAL MODEL; DNA REPAIR; GENE VECTOR; GENETIC ENGINEERING; GENETIC SCREENING; GENETICS; GERM CELL; HOMOLOGOUS RECOMBINATION; METABOLISM; PROCEDURES; TRANSGENIC ANIMAL; ZEBRA FISH;

DANIO RERIO;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; DNA REPAIR; DNA, SINGLE-STRANDED; ENDONUCLEASES; GENE KNOCK-IN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; GENETIC ENGINEERING; GENETIC TESTING; GENETIC VECTORS; GERM CELLS; HOMOLOGOUS RECOMBINATION; MODELS, ANIMAL; ZEBRAFISH;

EID: 84911870422     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-1862-1_17     Document Type: Article

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