Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo

EMBO Journal

Volumn 33, Issue 20, 2014, Pages 2295-2313

  Amoyel, Marc ^a   Simons, Benjamin D ^b,c,d   Bach, Erika A ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

competition; Hedgehog; Hippo; stem cell; testis

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE; GREEN FLUORESCENT PROTEIN; INSULIN RECEPTOR; JANUS KINASE; MATURATION PROMOTING FACTOR; MOLECULAR MARKER; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN; STAT PROTEIN; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; HEDGEHOG PROTEIN, DROSOPHILA; HPO PROTEIN, DROSOPHILA; PROTEIN SERINE THREONINE KINASE; PTC PROTEIN, DROSOPHILA; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL CLONE; CELL INTERACTION; CELL MUTANT; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DROSOPHILA; GENE MUTATION; GERM LINE; HEDGEHOG SIGNALING PATHWAY; HIPPO SIGNALING PATHWAY; HOMEOSTASIS; MALE; NONHUMAN; ONCOGENE; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL NICHE; TESTIS; WILD TYPE; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; METABOLISM; MUTATION; PHENOTYPE; PHYSIOLOGY; THEORETICAL MODEL;

ERINACEIDAE;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CLONE CELLS; DROSOPHILA; DROSOPHILA PROTEINS; HEDGEHOG PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MODELS, THEORETICAL; MUTATION; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELLS; TESTIS;

EID: 84911477699     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201387500     Document Type: Article

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