메뉴 건너뛰기




Volumn 137, Issue 3, 1996, Pages 846-856

The Drosophila insulin receptor is required for normal growth

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; PROTEIN TYROSINE KINASE;

EID: 0030060198     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.137.3.8603594     Document Type: Article
Times cited : (295)

References (47)
  • 2
    • 0028085078 scopus 로고
    • The insulin signaling system
    • White MF, Kahn CR 1994 The insulin signaling system. J Biol Chem 269:1-4
    • (1994) J Biol Chem , vol.269 , pp. 1-4
    • White, M.F.1    Kahn, C.R.2
  • 3
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger J, Ullrich A 1992 Growth factor signaling by receptor tyrosine kinases. Neuron 9:383-391
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 4
    • 0028221043 scopus 로고
    • Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila
    • Perrimon N 1994 Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila. Curr Opin Cell Biol 6:260-266
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 260-266
    • Perrimon, N.1
  • 5
    • 0016154855 scopus 로고
    • Insulin is a Drosophila hormone and acts to enhance the differentiation of embryonic Drosophila cells
    • Seecof RS, Dewhurst S 1974 Insulin is a Drosophila hormone and acts to enhance the differentiation of embryonic Drosophila cells. Cell Differ 3:63-70
    • (1974) Cell Differ , vol.3 , pp. 63-70
    • Seecof, R.S.1    Dewhurst, S.2
  • 6
    • 0028965549 scopus 로고
    • The Drosophila insulin receptor contains a novel carboxy-terminal extension likely to play an important role in signal transduction
    • Ruan Y, Chen C, Cao Y, Garofalo RS 1994 The Drosophila insulin receptor contains a novel carboxy-terminal extension likely to play an important role in signal transduction. J Biol Chem 270:4236-4243
    • (1994) J Biol Chem , vol.270 , pp. 4236-4243
    • Ruan, Y.1    Chen, C.2    Cao, Y.3    Garofalo, R.S.4
  • 7
    • 0023390967 scopus 로고
    • Structure and ligand specificity of the Drosophila melanogaster insulin receptor
    • Fernandez-Almonacid R, Rosen OM 1987 Structure and ligand specificity of the Drosophila melanogaster insulin receptor. Mol Cell Biol 7:2718-2727
    • (1987) Mol Cell Biol , vol.7 , pp. 2718-2727
    • Fernandez-Almonacid, R.1    Rosen, O.M.2
  • 9
    • 0242484309 scopus 로고
    • Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody
    • Petruzzelli LM, Herrera R, Arenas-Garcia R, Fernandez R, Birnbaum MJ, Rosen OM 1986 Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody. Proc Natl Acad Sci USA 83:4710-4714
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 4710-4714
    • Petruzzelli, L.M.1    Herrera, R.2    Arenas-Garcia, R.3    Fernandez, R.4    Birnbaum, M.J.5    Rosen, O.M.6
  • 10
    • 0022389345 scopus 로고
    • Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis
    • Petruzzelli L, Herrera R, Garcia-Arenas R, Rosen OM 1985 Acquisition of insulin-dependent protein tyrosine kinase activity during Drosophila embryogenesis. J Biol Chem 260:16072-16075
    • (1985) J Biol Chem , vol.260 , pp. 16072-16075
    • Petruzzelli, L.1    Herrera, R.2    Garcia-Arenas, R.3    Rosen, O.M.4
  • 11
    • 0029063485 scopus 로고
    • Drosophila insulin receptor: Lectin binding properties and a role for oxidation-reduction of receptor thiols in activation
    • Marin-Hincapie M, Garofalo RS 1995 Drosophila insulin receptor: lectin binding properties and a role for oxidation-reduction of receptor thiols in activation. Endocrinology 136:2357-2366
    • (1995) Endocrinology , vol.136 , pp. 2357-2366
    • Marin-Hincapie, M.1    Garofalo, R.S.2
  • 13
    • 0023929592 scopus 로고
    • Tissue localization of Drosophila melanogaster insulin receptor transcripts during development
    • Garofalo RS, Rosen OM 1988 Tissue localization of Drosophila melanogaster insulin receptor transcripts during development. Mol Cell Biol 8:1638-1647
    • (1988) Mol Cell Biol , vol.8 , pp. 1638-1647
    • Garofalo, R.S.1    Rosen, O.M.2
  • 14
    • 0025201880 scopus 로고
    • Insulin and insulin-like growth factor I in early development: Peptides, receptors and biological events
    • De Pablo F, Scott LA, Roth J 1990 Insulin and insulin-like growth factor I in early development: peptides, receptors and biological events. Endocr Rev 11:558-577
    • (1990) Endocr Rev , vol.11 , pp. 558-577
    • De Pablo, F.1    Scott, L.A.2    Roth, J.3
  • 15
    • 0024354214 scopus 로고
    • Insulin and insulin-like growth factor I (IGF-I) receptors during central nervous system development: Expression of two immunologically distinct IGF-I receptor beta subunits
    • Garofalo RS, Rosen OM 1989 Insulin and insulin-like growth factor I (IGF-I) receptors during central nervous system development: expression of two immunologically distinct IGF-I receptor beta subunits. Mol Cell Biol 9:2806-2817
    • (1989) Mol Cell Biol , vol.9 , pp. 2806-2817
    • Garofalo, R.S.1    Rosen, O.M.2
  • 17
    • 0002908132 scopus 로고
    • Mutagenesis
    • Roberts DB (ed) IRL Press, Washington, D.C.
    • Grigliatti T 1986 Mutagenesis. In: Roberts DB (ed) Drosophila, A Practical Approach. IRL Press, Washington, D.C., pp 39-58
    • (1986) Drosophila, A Practical Approach , pp. 39-58
    • Grigliatti, T.1
  • 18
    • 0021340907 scopus 로고
    • Mutational analysis of the region surrounding the 93D heat shock locus of Drosophila melanogaster
    • Mohler J, Pardue ML 1984 Mutational analysis of the region surrounding the 93D heat shock locus of Drosophila melanogaster. Genetics 106:249-265
    • (1984) Genetics , vol.106 , pp. 249-265
    • Mohler, J.1    Pardue, M.L.2
  • 19
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 20
    • 0019551730 scopus 로고
    • "Western Blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated Protein A
    • Burnette WN 1981 "Western Blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated Protein A. Anal Biochem 112:195-203
    • (1981) Anal Biochem , vol.112 , pp. 195-203
    • Burnette, W.N.1
  • 22
    • 84986522858 scopus 로고
    • Direct determination of the growth rate of Drosophila imaginai discs
    • Martin PF 1982 Direct determination of the growth rate of Drosophila imaginai discs. J Exp Zool 222:97-102
    • (1982) J Exp Zool , vol.222 , pp. 97-102
    • Martin, P.F.1
  • 23
    • 0023155309 scopus 로고
    • Proto-oncogenes in Drosophila melanogaster
    • Shilo B-Z 1987 Proto-oncogenes in Drosophila melanogaster. Trends Genet 3:69-72
    • (1987) Trends Genet , vol.3 , pp. 69-72
    • Shilo, B.-Z.1
  • 24
    • 0025938504 scopus 로고
    • Interallelic complementation among DER/flb alleles: Implications for the mechanism of signal transduction by receptor-tyrosine kinases
    • Raz E, Schejter ED, Shilo B-Z 1991 Interallelic complementation among DER/flb alleles: implications for the mechanism of signal transduction by receptor-tyrosine kinases. Genetics 129:191-201
    • (1991) Genetics , vol.129 , pp. 191-201
    • Raz, E.1    Schejter, E.D.2    Shilo, B.-Z.3
  • 25
    • 0001085592 scopus 로고
    • Imaginai disc development
    • Bate M, Martinez Arias A (eds) Cold Spring Harbor Laboratory Press, New York
    • Cohen SM 1993 Imaginai disc development. In: Bate M, Martinez Arias A (eds) The Development of Drosophila melanogaster. Cold Spring Harbor Laboratory Press, New York, pp 747-841
    • (1993) The Development of Drosophila Melanogaster , pp. 747-841
    • Cohen, S.M.1
  • 26
    • 0024510368 scopus 로고
    • The Drosophila EGF receptor homolog (DER) gene is allelic to faint little ball, a locus essential for embryonic development
    • Schejter ED, Shilo B-Z 1989 The Drosophila EGF receptor homolog (DER) gene is allelic to faint little ball, a locus essential for embryonic development. Cell 56:1093-1104
    • (1989) Cell , vol.56 , pp. 1093-1104
    • Schejter, E.D.1    Shilo, B.-Z.2
  • 28
    • 0023814924 scopus 로고
    • Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity
    • White MF, Livingston JN, Backer JM, Lauris V, Dull TJ, Ullrich A, Kahn CR 1988 Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity. Cell 54:641-649
    • (1988) Cell , vol.54 , pp. 641-649
    • White, M.F.1    Livingston, J.N.2    Backer, J.M.3    Lauris, V.4    Dull, T.J.5    Ullrich, A.6    Kahn, C.R.7
  • 29
    • 0026083942 scopus 로고
    • A mutation in the extracellular domain of the insulin receptor impairs the ability of insulin to stimulate receptor autophosphorylation
    • Accili D, Mosthaf L, Ullrich A, Taylor SI 1991 A mutation in the extracellular domain of the insulin receptor impairs the ability of insulin to stimulate receptor autophosphorylation. J Biol Chem 266: 434-439
    • (1991) J Biol Chem , vol.266 , pp. 434-439
    • Accili, D.1    Mosthaf, L.2    Ullrich, A.3    Taylor, S.I.4
  • 31
    • 0025653446 scopus 로고
    • The genetic control of cell proliferation in Drosophila imaginai discs
    • Bryant PJ, Schmidt O 1990 The genetic control of cell proliferation in Drosophila imaginai discs. J Cell Sci [Suppl] 13:169-189
    • (1990) J Cell Sci [Suppl] , vol.13 , pp. 169-189
    • Bryant, P.J.1    Schmidt, O.2
  • 32
    • 0017143415 scopus 로고
    • A temperature sensitive mutation that reduces mitotic rate in Drosophila melanogaster
    • Simpson P, Schneiderman HA 1976 A temperature sensitive mutation that reduces mitotic rate in Drosophila melanogaster. Wilhelm Roux' Arch Dev Biol 179:215-236
    • (1976) Wilhelm Roux' Arch Dev Biol , vol.179 , pp. 215-236
    • Simpson, P.1    Schneiderman, H.A.2
  • 33
    • 0017150826 scopus 로고
    • Analysis of the compartments of the wing of Drosophila melanogaster mosaic for a temperature-sensitive mutation that reduces mitotic rate
    • Simpson P 1976 Analysis of the compartments of the wing of Drosophila melanogaster mosaic for a temperature-sensitive mutation that reduces mitotic rate. Dev Biol 54:100-115
    • (1976) Dev Biol , vol.54 , pp. 100-115
    • Simpson, P.1
  • 34
    • 0023976715 scopus 로고
    • Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene
    • Nishida Y, Hata M, Ayaki T, Ryo H, Yamagata M, Shimizu K, Nishizuka Y 1988 Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene. EMBO J 7:775-781
    • (1988) EMBO J , vol.7 , pp. 775-781
    • Nishida, Y.1    Hata, M.2    Ayaki, T.3    Ryo, H.4    Yamagata, M.5    Shimizu, K.6    Nishizuka, Y.7
  • 35
    • 0024972524 scopus 로고
    • Requirement of the Drosophila raf homologue for torso function
    • Ambrosio L, Mahowald AP, Perrimon N 1989 Requirement of the Drosophila raf homologue for torso function. Nature 342:288-291
    • (1989) Nature , vol.342 , pp. 288-291
    • Ambrosio, L.1    Mahowald, A.P.2    Perrimon, N.3
  • 37
    • 0024382967 scopus 로고
    • Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor
    • Morrison DK, Kaplan DR, Escobedo JA, Rapp UR, Roberts TM, Williams LT 1989 Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor. Cell 58:649-657
    • (1989) Cell , vol.58 , pp. 649-657
    • Morrison, D.K.1    Kaplan, D.R.2    Escobedo, J.A.3    Rapp, U.R.4    Roberts, T.M.5    Williams, L.T.6
  • 38
    • 0021661051 scopus 로고
    • Intrinsic and extrinsic control of growth in developing organs
    • Bryant PJ, Simpson P 1984 Intrinsic and extrinsic control of growth in developing organs. Q Rev Biol 59:387-415
    • (1984) Q Rev Biol , vol.59 , pp. 387-415
    • Bryant, P.J.1    Simpson, P.2
  • 39
    • 0015136773 scopus 로고
    • Imaginai disc abnormalities in lethal mutants of Drosophila
    • Shearn A, Rice T, Garen A, Gehring W 1971 Imaginai disc abnormalities in lethal mutants of Drosophila. Proc Natl Acad Sci USA 68:2594-2598
    • (1971) Proc Natl Acad Sci USA , vol.68 , pp. 2594-2598
    • Shearn, A.1    Rice, T.2    Garen, A.3    Gehring, W.4
  • 40
    • 0002031074 scopus 로고
    • Developmental Genetics of Oogenesis
    • Bate M, Martinez Arias A (eds) Cold Spring Harbor Laboratory Press, New York
    • Spradling AC 1993 Developmental Genetics of Oogenesis. In: Bate M, Martinez Arias A (eds) The Development of Drosophila melanogaster. Cold Spring Harbor Laboratory Press, New York, 1:1-70
    • (1993) The Development of Drosophila Melanogaster , vol.1 , pp. 1-70
    • Spradling, A.C.1
  • 41
    • 0025945012 scopus 로고
    • Insulin resistance-mechanisms, syndromes and implications
    • Moller DE, Flier JS 1991 Insulin resistance-mechanisms, syndromes and implications. New Engl J Med 325:938-948
    • (1991) New Engl J Med , vol.325 , pp. 938-948
    • Moller, D.E.1    Flier, J.S.2
  • 42
    • 0022376346 scopus 로고
    • Insulin antibodies retard and insulin accelerates growth and differentiation in early embryos
    • DePablo F, Girbau M, Gomez JA, Hernandez E, Roth J 1985 Insulin antibodies retard and insulin accelerates growth and differentiation in early embryos. Diabetes 34:1063-1067
    • (1985) Diabetes , vol.34 , pp. 1063-1067
    • Depablo, F.1    Girbau, M.2    Gomez, J.A.3    Hernandez, E.4    Roth, J.5
  • 43
    • 0023891370 scopus 로고
    • Insulin action in early embryonic life: Anti-insulin receptor antibodies retard chicken embryo growth but not muscle differentiation in vivo
    • Girbau M, Lesniak MA, Gomez JA, DePablo F 1988 Insulin action in early embryonic life: anti-insulin receptor antibodies retard chicken embryo growth but not muscle differentiation in vivo. Biochem Biophys Res Commun 153:142-148
    • (1988) Biochem Biophys Res Commun , vol.153 , pp. 142-148
    • Girbau, M.1    Lesniak, M.A.2    Gomez, J.A.3    DePablo, F.4
  • 44
    • 0025320906 scopus 로고
    • A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting
    • DeChiara TM, Efstratiadis A, Robertson EJ 1990 A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting. Nature 345: 78-80
    • (1990) Nature , vol.345 , pp. 78-80
    • Dechiara, T.M.1    Efstratiadis, A.2    Robertson, E.J.3
  • 45
    • 0027496895 scopus 로고
    • Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
    • Liu J-P, Baker J, Perkins AS, Robertson EJ, Efstratiadis A 1993 Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:59-72
    • (1993) Cell , vol.75 , pp. 59-72
    • Liu, J.-P.1    Baker, J.2    Perkins, A.S.3    Robertson, E.J.4    Efstratiadis, A.5
  • 46
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J, Liu J-P, Robertson EJ, Efstratiadis A 1993 Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75: 73-82
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.-P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 47
    • 0027366338 scopus 로고
    • Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor
    • Sell C, Rubini M, Rubin R, Liu JP, Efstratiadis A, Baserga R 1993 Simian virus 40 large tumor antigen is unable to transform mouse embryonic fibroblasts lacking type 1 insulin-like growth factor receptor. Proc Natl Acad Sci USA 90:11217-11221
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11217-11221
    • Sell, C.1    Rubini, M.2    Rubin, R.3    Liu, J.P.4    Efstratiadis, A.5    Baserga, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.