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Volumn 20, Issue 37, 2014, Pages 5853-5861

Regulation and function of Rankl in arterial calcification

Author keywords

Arterial calcification; Osteoprotegerin (OPG); Receptor activator of nuclear factor B ligand (RANKL); Tumour necrosis factor related apoptosisinducing ligand (TRAIL)

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TNFSF11 PROTEIN, HUMAN;

EID: 84911466832     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612820666140212205455     Document Type: Article
Times cited : (6)

References (113)
  • 1
    • 44649133999 scopus 로고    scopus 로고
    • Vascular calcification: Pathobiology of a multifaceted disease
    • Demer LL, Tintut Y. Vascular calcification: pathobiology of a multifaceted disease. Circulation 2008; 117: 2938-48.
    • (2008) Circulation , vol.117 , pp. 2938-2948
    • Demer, L.L.1    Tintut, Y.2
  • 2
    • 84859590913 scopus 로고    scopus 로고
    • Vascular calcification, diabetes, and cardiovascular disease: Connecting the dots. JACC
    • Kovacic JC, Fuster V. Vascular calcification, diabetes, and cardiovascular disease: connecting the dots. JACC. Cardiovascular Imaging 2012; 5: 367-9.
    • (2012) Cardiovascular Imaging , vol.5 , pp. 367-369
    • Kovacic, J.C.1    Fuster, V.2
  • 3
    • 39049096394 scopus 로고    scopus 로고
    • Mechanisms of vascular calcification in chronic kidney disease
    • Moe SM, Chen NX. Mechanisms of vascular calcification in chronic kidney disease. J Am Soc Nephrol: JASN 2008; 19: 213-6.
    • (2008) J Am Soc Nephrol: JASN , vol.19 , pp. 213-216
    • Moe, S.M.1    Chen, N.X.2
  • 4
    • 20444373191 scopus 로고    scopus 로고
    • Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: The St. Francis Heart Study
    • Arad Y, Goodman KJ, Roth M, Newstein D, Guerci AD. Coronary calcification, coronary disease risk factors, C-reactive protein, and atherosclerotic cardiovascular disease events: the St. Francis Heart Study. J Am College Cardiol 2005; 46: 158-65.
    • (2005) J Am College Cardiol , vol.46 , pp. 158-165
    • Arad, Y.1    Goodman, K.J.2    Roth, M.3    Newstein, D.4    Guerci, A.D.5
  • 5
    • 0034616810 scopus 로고    scopus 로고
    • Calcification of the aortic arch: Risk factors and association with coronary heart disease, stroke, and peripheral vascular disease
    • Iribarren C, Sidney S, Sternfeld B, Browner WS. Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. JAMA: J Am Med Assoc 2000; 283: 2810-5.
    • (2000) JAMA: J Am Med Assoc , vol.283 , pp. 2810-2815
    • Iribarren, C.1    Sidney, S.2    Sternfeld, B.3    Browner, W.S.4
  • 6
  • 7
    • 67649678424 scopus 로고    scopus 로고
    • Vascular calcification: The killer of patients with chronic kidney disease
    • Mizobuchi M, Towler D, Slatopolsky E. Vascular calcification: the killer of patients with chronic kidney disease. J Am Soc Nephrol: JASN 2009; 20: 1453-64.
    • (2009) J Am Soc Nephrol: JASN , vol.20 , pp. 1453-1464
    • Mizobuchi, M.1    Towler, D.2    Slatopolsky, E.3
  • 10
    • 84865688452 scopus 로고    scopus 로고
    • Vascular calcification: Pathophysiology and risk factors
    • Chen NX, Moe SM. Vascular calcification: pathophysiology and risk factors. Curr Hypertension Reports 2012; 14: 228-37.
    • (2012) Curr Hypertension Reports , vol.14 , pp. 228-237
    • Chen, N.X.1    Moe, S.M.2
  • 11
    • 0141920487 scopus 로고    scopus 로고
    • Calciphylaxis and vascular calcification: A continuum of extra-skeletal osteogenesis
    • Moe SM, Chen NX. Calciphylaxis and vascular calcification: a continuum of extra-skeletal osteogenesis. Pediatric nephrology 2003; 18: 969-75.
    • (2003) Pediatric nephrology , vol.18 , pp. 969-975
    • Moe, S.M.1    Chen, N.X.2
  • 12
    • 0141817707 scopus 로고    scopus 로고
    • Calcification in atherosclerosis: Bone biology and chronic inflammation at the arterial crossroads
    • Doherty TM, Asotra K, Fitzpatrick LA, et al. Calcification in atherosclerosis: bone biology and chronic inflammation at the arterial crossroads. Proc Natl Acad Sci USA 2003; 100: 11201-6.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11201-11206
    • Doherty, T.M.1    Asotra, K.2    Fitzpatrick, L.A.3
  • 13
    • 79957463868 scopus 로고    scopus 로고
    • Runx2-upregulated receptor activator of nuclear factor kappaB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages
    • Byon CH, Sun Y, Chen J, et al. Runx2-upregulated receptor activator of nuclear factor kappaB ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation of macrophages. Arteriosclerosis, Thrombosis, Vascular Biol 2011; 31: 1387-96.
    • (2011) Arteriosclerosis, Thrombosis, Vascular Biol , vol.31 , pp. 1387-1396
    • Byon, C.H.1    Sun, Y.2    Chen, J.3
  • 14
    • 84871222459 scopus 로고    scopus 로고
    • Enhanced mineralization potential of vascular cells from SM22alpha-Rankl (tg) mice
    • Morony S, Sage AP, Corbin T, Lu J, Tintut Y, Demer LL. Enhanced mineralization potential of vascular cells from SM22alpha-Rankl (tg) mice. Calcified Tissue Int 2012; 91: 379-86.
    • (2012) Calcified Tissue Int , vol.91 , pp. 379-386
    • Morony, S.1    Sage, A.P.2    Corbin, T.3    Lu, J.4    Tintut, Y.5    Demer, L.L.6
  • 15
    • 80052829942 scopus 로고    scopus 로고
    • The RANKL/RANK/OPG signaling pathway mediates medial arterial calcification in diabetic Charcot neuroarthropathy
    • Ndip A, Williams A, Jude EB, et al The RANKL/RANK/OPG signaling pathway mediates medial arterial calcification in diabetic Charcot neuroarthropathy. Diabetes 2011; 60: 2187-96.
    • (2011) Diabetes , vol.60 , pp. 2187-2196
    • Ndip, A.1    Williams, A.2    Jude, E.B.3
  • 16
    • 77956226790 scopus 로고    scopus 로고
    • Estrogen inhibits vascular calcification via vascular RANKL system: Common mechanism of osteoporosis and vascular calcification
    • Osako MK, Nakagami H, Koibuchi N, et al. Estrogen inhibits vascular calcification via vascular RANKL system: common mechanism of osteoporosis and vascular calcification. Circulation Res 2010; 107: 466-75.
    • (2010) Circulation Res , vol.107 , pp. 466-475
    • Osako, M.K.1    Nakagami, H.2    Koibuchi, N.3
  • 17
    • 66149095438 scopus 로고    scopus 로고
    • RANKL increases vascular smooth muscle cell calcification through a RANK-BMP4-dependent pathway
    • Panizo S, Cardus A, Encinas M, et al. RANKL increases vascular smooth muscle cell calcification through a RANK-BMP4-dependent pathway. Circulation Res 2009; 104: 1041-8.
    • (2009) Circulation Res , vol.104 , pp. 1041-1048
    • Panizo, S.1    Cardus, A.2    Encinas, M.3
  • 18
    • 83455205924 scopus 로고    scopus 로고
    • RANKL is a downstream mediator for insulin-induced osteoblastic differentiation of vascular smooth muscle cells
    • Yuan LQ, Zhu JH, Wang HW, et al. RANKL is a downstream mediator for insulin-induced osteoblastic differentiation of vascular smooth muscle cells. PLoS One 2011; 6: e29037.
    • (2011) PLoS One , vol.6
    • Yuan, L.Q.1    Zhu, J.H.2    Wang, H.W.3
  • 19
    • 34249294496 scopus 로고    scopus 로고
    • Clinical, cellular, and molecular aspects of arterial calcification
    • Guzman RJ. Clinical, cellular, and molecular aspects of arterial calcification. J Vasc Surg 2007; 45 Suppl A: A57-63.
    • (2007) J Vasc Surg , vol.45 , pp. A57-A63
    • Guzman, R.J.1
  • 20
    • 0030714605 scopus 로고    scopus 로고
    • A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
    • Anderson DM, Maraskovsky E, Billingsley WL, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997; 390: 175-9.
    • (1997) Nature , vol.390 , pp. 175-179
    • Anderson, D.M.1    Maraskovsky, E.2    Billingsley, W.L.3
  • 21
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey DL, Timms E, Tan HL, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998; 93: 165-76.
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3
  • 22
    • 0030989969 scopus 로고    scopus 로고
    • Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis
    • Tsuda E, Goto M, Mochizuki S, et al. Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. Biochem Biophys Res Communicat 1997; 234: 137-42.
    • (1997) Biochem Biophys Res Communicat , vol.234 , pp. 137-142
    • Tsuda, E.1    Goto, M.2    Mochizuki, S.3
  • 23
    • 14444272043 scopus 로고    scopus 로고
    • TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells
    • Wong BR, Rho J, Arron J, et al. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. J biological chemistry 1997; 272: 25190-4.
    • (1997) J biological chemistry , vol.272 , pp. 25190-25194
    • Wong, B.R.1    Rho, J.2    Arron, J.3
  • 24
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda H, Shima N, Nakagawa N, et al. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 1998; 95: 3597-602.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 25
    • 77950537989 scopus 로고    scopus 로고
    • Control of RANKL gene expression
    • O’Brien CA. Control of RANKL gene expression. Bone 2010; 46: 911-9.
    • (2010) Bone , vol.46 , pp. 911-919
    • O’Brien, C.A.1
  • 26
    • 0033848680 scopus 로고    scopus 로고
    • Importance of membrane-or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors
    • Itoh K, Udagawa N, Matsuzaki K, et al. Importance of membrane-or matrix-associated forms of M-CSF and RANKL/ODF in osteoclastogenesis supported by SaOS-4/3 cells expressing recombinant PTH/PTHrP receptors. J bone and mineral research: the official J Am Soc Bone Mineral Res 2000; 15: 1766-75.
    • (2000) J bone and mineral research: The official J Am Soc Bone Mineral Res , vol.15 , pp. 1766-1775
    • Itoh, K.1    Udagawa, N.2    Matsuzaki, K.3
  • 27
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong YY, Yoshida H, Sarosi I, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999; 397: 315-23.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1    Yoshida, H.2    Sarosi, I.3
  • 28
    • 33845994375 scopus 로고    scopus 로고
    • Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand
    • Hikita A, Yana I, Wakeyama H, et al. Negative regulation of osteoclastogenesis by ectodomain shedding of receptor activator of NF-kappaB ligand. J biological chemistry 2006; 281: 36846-55.
    • (2006) J biological chemistry , vol.281 , pp. 36846-36855
    • Hikita, A.1    Yana, I.2    Wakeyama, H.3
  • 29
    • 0033532191 scopus 로고    scopus 로고
    • Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival
    • Lum L, Wong BR, Josien R, et al. Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival. J Biological Chem 1999; 274: 13613-8.
    • (1999) J Biological Chem , vol.274 , pp. 13613-13618
    • Lum, L.1    Wong, B.R.2    Josien, R.3
  • 30
    • 0034673525 scopus 로고    scopus 로고
    • Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation
    • Nagai M, Kyakumoto S, Sato N. Cancer cells responsible for humoral hypercalcemia express mRNA encoding a secreted form of ODF/TRANCE that induces osteoclast formation. Biochemical Biophysical Res Communicat 2000; 269: 532-6.
    • (2000) Biochemical Biophysical Res Communicat , vol.269 , pp. 532-536
    • Nagai, M.1    Kyakumoto, S.2    Sato, N.3
  • 31
    • 84880919124 scopus 로고    scopus 로고
    • Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL
    • Walsh NC, Alexander KA, Manning CA, et al. Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL. Genes Immunity 2013; 14: 336-45.
    • (2013) Genes Immunity , vol.14 , pp. 336-345
    • Walsh, N.C.1    Alexander, K.A.2    Manning, C.A.3
  • 32
    • 77953623660 scopus 로고    scopus 로고
    • Structural and functional insights of RANKL-RANK interaction and signaling
    • Liu C, Walter TS, Huang P, et al. Structural and functional insights of RANKL-RANK interaction and signaling. J immunol 2010; 184: 6910-9.
    • (2010) J immunol , vol.184 , pp. 6910-6919
    • Liu, C.1    Walter, T.S.2    Huang, P.3
  • 33
    • 84862884060 scopus 로고    scopus 로고
    • Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin
    • Luan X, Lu Q, Jiang Y, et al. Crystal structure of human RANKL complexed with its decoy receptor osteoprotegerin. J immunol 2012; 189: 245-52.
    • (2012) J immunol , vol.189 , pp. 245-252
    • Luan, X.1    Lu, Q.2    Jiang, Y.3
  • 36
    • 45349091141 scopus 로고    scopus 로고
    • Molecular biology of bone remodelling
    • Rucci N. Molecular biology of bone remodelling. Clin Cases Miner Bone Metab 2008; 5: 49-56.
    • (2008) Clin Cases Miner Bone Metab , vol.5 , pp. 49-56
    • Rucci, N.1
  • 37
    • 34547521058 scopus 로고    scopus 로고
    • Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL
    • Sobacchi C, Frattini A, Guerrini MM, et al. Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL. Nature Genet 2007; 39: 960-2.
    • (2007) Nature Genet , vol.39 , pp. 960-962
    • Sobacchi, C.1    Frattini, A.2    Guerrini, M.M.3
  • 38
    • 46349084493 scopus 로고    scopus 로고
    • Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations
    • Guerrini MM, Sobacchi C, Cassani B, et al. Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am J Hum Genet 2008; 83: 64-76.
    • (2008) Am J Hum Genet , vol.83 , pp. 64-76
    • Guerrini, M.M.1    Sobacchi, C.2    Cassani, B.3
  • 39
    • 3242781731 scopus 로고    scopus 로고
    • Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases
    • Hofbauer LC, Schoppet M. Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases. JAMA: the J Am Med Associat 2004; 292: 490-5.
    • (2004) JAMA: The J Am Med Associat , vol.292 , pp. 490-495
    • Hofbauer, L.C.1    Schoppet, M.2
  • 40
    • 84868488604 scopus 로고    scopus 로고
    • New developments in osteoimmunology
    • Takayanagi H. New developments in osteoimmunology. Nature Rev Rheumatol 2012; 8: 684-9.
    • (2012) Nature Rev Rheumatol , vol.8 , pp. 684-689
    • Takayanagi, H.1
  • 41
    • 0035827692 scopus 로고    scopus 로고
    • Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis
    • Collin-Osdoby P, Rothe L, Anderson F, Nelson M, Maloney W, Osdoby P. Receptor activator of NF-kappa B and osteoprotegerin expression by human microvascular endothelial cells, regulation by inflammatory cytokines, and role in human osteoclastogenesis. J Biological Chem 2001; 276: 20659-72.
    • (2001) J Biological Chem , vol.276 , pp. 20659-20672
    • Collin-Osdoby, P.1    Rothe, L.2    Anderson, F.3    Nelson, M.4    Maloney, W.5    Osdoby, P.6
  • 42
    • 33646441388 scopus 로고    scopus 로고
    • Enhanced T-cell expression of RANK ligand in acute coronary syndrome: Possible role in plaque destabilization
    • Sandberg WJ, Yndestad A, Oie E, et al. Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization. Arteriosclerosis, Thrombosis, Vascular Biol 2006; 26: 857-63.
    • (2006) Arteriosclerosis, Thrombosis, Vascular Biol , vol.26 , pp. 857-863
    • Sandberg, W.J.1    Yndestad, A.2    Oie, E.3
  • 44
    • 4043158681 scopus 로고    scopus 로고
    • Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Monckeberg’s sclerosis and atherosclerosis
    • Schoppet M, Al-Fakhri N, Franke FE, et al. Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Monckeberg’s sclerosis and atherosclerosis. J Clin Endocrinol Metab 2004; 89: 4104-12.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4104-4112
    • Schoppet, M.1    Al-Fakhri, N.2    Franke, F.E.3
  • 45
    • 0035571591 scopus 로고    scopus 로고
    • Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques
    • Dhore CR, Cleutjens JP, Lutgens E, et al. Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques. Arterioscler Thromb Vasc Biol 2001; 21: 1998-2003.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1998-2003
    • Dhore, C.R.1    Cleutjens, J.P.2    Lutgens, E.3
  • 47
    • 38349133382 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice
    • Morony S, Tintut Y, Zhang Z, et al. Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in ldlr(-/-) mice. Circulation 2008; 117: 411-20.
    • (2008) Circulation , vol.117 , pp. 411-420
    • Morony, S.1    Tintut, Y.2    Zhang, Z.3
  • 48
    • 68449102008 scopus 로고    scopus 로고
    • Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice
    • Helas S, Goettsch C, Schoppet M, et al. Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice. Am J Pathol 2009; 175: 473-8.
    • (2009) Am J Pathol , vol.175 , pp. 473-478
    • Helas, S.1    Goettsch, C.2    Schoppet, M.3
  • 49
    • 84865593466 scopus 로고    scopus 로고
    • RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: Dependence on IL-6 and TNF-alpha
    • Deuell KA, Callegari A, Giachelli CM, Rosenfeld ME, Scatena M. RANKL enhances macrophage paracrine pro-calcific activity in high phosphate-treated smooth muscle cells: dependence on IL-6 and TNF-alpha. J Vascular Res 2012; 49: 510-21.
    • (2012) J Vascular Res , vol.49 , pp. 510-521
    • Deuell, K.A.1    Callegari, A.2    Giachelli, C.M.3    Rosenfeld, M.E.4    Scatena, M.5
  • 51
    • 84876454779 scopus 로고    scopus 로고
    • Cell adhesion signaling regulates RANK expression in osteoclast precursors
    • Mochizuki A, Takami M, Miyamoto Y, et al. Cell adhesion signaling regulates RANK expression in osteoclast precursors. PLoS One 2012; 7: e48795.
    • (2012) PLoS One , vol.7
    • Mochizuki, A.1    Takami, M.2    Miyamoto, Y.3
  • 53
    • 22744434737 scopus 로고    scopus 로고
    • Bone morphogenetic proteins in vascular calcification
    • Hruska KA, Mathew S, Saab G. Bone morphogenetic proteins in vascular calcification. Circulation research 2005; 97: 105-14.
    • (2005) Circulation research , vol.97 , pp. 105-114
    • Hruska, K.A.1    Mathew, S.2    Saab, G.3
  • 54
    • 0032079445 scopus 로고    scopus 로고
    • Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
    • Bucay N, Sarosi I, Dunstan CR, et al. osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification. Genes Dev 1998; 12: 1260-8.
    • (1998) Genes Dev , vol.12 , pp. 1260-1268
    • Bucay, N.1    Sarosi, I.2    Dunstan, C.R.3
  • 55
    • 0034698926 scopus 로고    scopus 로고
    • Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis
    • Min H, Morony S, Sarosi I, et al. Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis. J Exp Med 2000; 192: 463-74.
    • (2000) J Exp Med , vol.192 , pp. 463-474
    • Min, H.1    Morony, S.2    Sarosi, I.3
  • 56
    • 84887108648 scopus 로고    scopus 로고
    • Bone marrow-or vessel wall-derived osteoprotegerin is sufficient to reduce atherosclerotic lesion size and vascular calcification
    • Callegari A, Coons ML, Ricks JL, et al. Bone marrow-or vessel wall-derived osteoprotegerin is sufficient to reduce atherosclerotic lesion size and vascular calcification. Arterioscler Thromb Vasc Biol 2013; 33: 2491-500.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 2491-2500
    • Callegari, A.1    Coons, M.L.2    Ricks, J.L.3
  • 57
    • 0034102960 scopus 로고    scopus 로고
    • Assay for human matrix gla protein in serum: Potential applications in the cardiovascular field
    • Braam LA, Dissel P, Gijsbers BL, et al. Assay for human matrix gla protein in serum: potential applications in the cardiovascular field. Arteriosclerosis, thrombosis, and vascular biology 2000; 20: 1257-61.
    • (2000) Arteriosclerosis, thrombosis, and vascular biology , vol.20 , pp. 1257-1261
    • Braam, L.A.1    Dissel, P.2    Gijsbers, B.L.3
  • 58
    • 0030947025 scopus 로고    scopus 로고
    • Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
    • Luo G, Ducy P, McKee MD, et al. Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature 1997; 386: 78-81.
    • (1997) Nature , vol.386 , pp. 78-81
    • Luo, G.1    Ducy, P.2    McKee, M.D.3
  • 60
    • 84876136816 scopus 로고    scopus 로고
    • The role of osteoprotegerin in cardiovascular disease
    • Montagnana M, Lippi G, Danese E, Guidi GC. The role of osteoprotegerin in cardiovascular disease. Ann Med 2013; 45: 254-64.
    • (2013) Ann Med , vol.45 , pp. 254-264
    • Montagnana, M.1    Lippi, G.2    Danese, E.3    Guidi, G.C.4
  • 61
    • 67349099856 scopus 로고    scopus 로고
    • Osteoprotegerin, vascular calcification and atherosclerosis
    • Van Campenhout A, Golledge J. Osteoprotegerin, vascular calcification and atherosclerosis. Atherosclerosis 2009; 204: 321-9.
    • (2009) Atherosclerosis , vol.204 , pp. 321-329
    • Van Campenhout, A.1    Golledge, J.2
  • 62
    • 9344246863 scopus 로고    scopus 로고
    • Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin
    • Collin-Osdoby P. Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerin. Circ Res 2004; 95: 1046-57.
    • (2004) Circ Res , vol.95 , pp. 1046-1057
    • Collin-Osdoby, P.1
  • 63
    • 0035094860 scopus 로고    scopus 로고
    • Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women
    • Browner WS, Lui LY, Cummings SR. Associations of serum osteoprotegerin levels with diabetes, stroke, bone density, fractures, and mortality in elderly women. J Clin Endocrinol Metab 2001; 86: 631-7.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 631-637
    • Browner, W.S.1    Lui, L.Y.2    Cummings, S.R.3
  • 64
    • 0037015255 scopus 로고    scopus 로고
    • Serum osteoprotegerin levels are associated with the presence and severity of coronary artery disease
    • Jono S, Ikari Y, Shioi A, et al. Serum osteoprotegerin levels are associated with the presence and severity of coronary artery disease. Circulation 2002; 106: 1192-4.
    • (2002) Circulation , vol.106 , pp. 1192-1194
    • Jono, S.1    Ikari, Y.2    Shioi, A.3
  • 66
    • 0037466084 scopus 로고    scopus 로고
    • Low serum levels of soluble RANK ligand are associated with the presence of coronary artery disease in men
    • author reply e76
    • Schoppet M, Schaefer JR, Hofbauer LC. Low serum levels of soluble RANK ligand are associated with the presence of coronary artery disease in men. Circulation 2003; 107: e76; author reply e76.
    • (2003) Circulation , vol.107
    • Schoppet, M.1    Schaefer, J.R.2    Hofbauer, L.C.3
  • 67
    • 40649099588 scopus 로고    scopus 로고
    • Expression, regulation and function of trail in atherosclerosis
    • Kavurma MM, Bennett MR. Expression, regulation and function of trail in atherosclerosis. Biochem Pharmacol 2008; 75: 1441-50.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1441-1450
    • Kavurma, M.M.1    Bennett, M.R.2
  • 68
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the TNF family that induces apoptosis
    • Wiley SR, Schooley K, Smolak PJ, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 2: 673-82.
    • (1995) Immunity , vol.2 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3
  • 70
    • 84884349409 scopus 로고    scopus 로고
    • Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand
    • 10.1007
    • Azahri NS, Kavurma MM. Transcriptional regulation of tumour necrosis factor-related apoptosis-inducing ligand. Cell Mol Life Sci 2013; 70(19): 3617-29. doi: 10. 1007.
    • (2013) Cell Mol Life Sci , vol.70 , Issue.19 , pp. 3617-3629
    • Azahri, N.S.1    Kavurma, M.M.2
  • 71
    • 40149109157 scopus 로고    scopus 로고
    • TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells
    • Yen ML, Tsai HF, Wu YY, Hwa HL, Lee BH, Hsu PN. TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. Molecular immunology 2008; 45: 2205-13.
    • (2008) Molecular immunology , vol.45 , pp. 2205-2213
    • Yen, M.L.1    Tsai, H.F.2    Wu, Y.Y.3    Hwa, H.L.4    Lee, B.H.5    Hsu, P.N.6
  • 72
    • 84862263981 scopus 로고    scopus 로고
    • TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation
    • Yen ML, Hsu PN, Liao HJ, Lee BH, Tsai HF. TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation. PLoS One 2012; 7: e38048.
    • (2012) PLoS One , vol.7
    • Yen, M.L.1    Hsu, P.N.2    Liao, H.J.3    Lee, B.H.4    Tsai, H.F.5
  • 75
    • 84883507476 scopus 로고    scopus 로고
    • TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL
    • 10.1371
    • Di Bartolo BA, Cartland SP, Harith HH, Bobryshev Y, Schoppet M, Kavurma MM. TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL. PLoS One 2013; 8(9): e74211. doi: 10. 1371.
    • (2013) PLoS One , vol.8 , Issue.9
    • Di Bartolo, B.A.1    Cartland, S.P.2    Harith, H.H.3    Bobryshev, Y.4    Schoppet, M.5    Kavurma, M.M.6
  • 76
    • 0029148659 scopus 로고
    • Modulation of osteoclast differentiation by local factors
    • Suda T, Udagawa N, Nakamura I, Miyaura C, Takahashi N. Modulation of osteoclast differentiation by local factors. Bone 1995; 17: 87S-91S.
    • (1995) Bone , vol.17 , pp. 87S-91S
    • Suda, T.1    Udagawa, N.2    Nakamura, I.3    Miyaura, C.4    Takahashi, N.5
  • 77
    • 0023928381 scopus 로고
    • Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures
    • Takahashi N, Yamana H, Yoshiki S, et al. Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures. Endocrinology 1988; 122: 1373-82.
    • (1988) Endocrinology , vol.122 , pp. 1373-1382
    • Takahashi, N.1    Yamana, H.2    Yoshiki, S.3
  • 78
    • 0033305046 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: Correlation with osteoclast-like cell formation
    • Lee SK, Lorenzo JA. Parathyroid hormone stimulates TRANCE and inhibits osteoprotegerin messenger ribonucleic acid expression in murine bone marrow cultures: correlation with osteoclast-like cell formation. Endocrinology 1999; 140: 3552-61.
    • (1999) Endocrinology , vol.140 , pp. 3552-3561
    • Lee, S.K.1    Lorenzo, J.A.2
  • 79
    • 0033623876 scopus 로고    scopus 로고
    • Prostaglandin E2 induces expression of receptor activator of nuclear factor-kappa B ligand/osteoprotegrin ligand on pre-B cells: Implications for accelerated osteoclastogenesis in estrogen deficiency
    • Kanematsu M, Sato T, Takai H, Watanabe K, Ikeda K, Yamada Y. Prostaglandin E2 induces expression of receptor activator of nuclear factor-kappa B ligand/osteoprotegrin ligand on pre-B cells: implications for accelerated osteoclastogenesis in estrogen deficiency. J bone and mineral research: the official J Am Society Bone Mineral Res 2000; 15: 1321-9.
    • (2000) J bone and mineral research: The official J Am Society Bone Mineral Res , vol.15 , pp. 1321-1329
    • Kanematsu, M.1    Sato, T.2    Takai, H.3    Watanabe, K.4    Ikeda, K.5    Yamada, Y.6
  • 80
    • 1642313645 scopus 로고    scopus 로고
    • Regulatory effects of interleukin-1beta and prostaglandin E2 on expression of receptor activator of nuclear factor-kappaB ligand in human periodontal ligament cells
    • Nukaga J, Kobayashi M, Shinki T, et al. Regulatory effects of interleukin-1beta and prostaglandin E2 on expression of receptor activator of nuclear factor-kappaB ligand in human periodontal ligament cells. J Periodontol 2004; 75: 249-59.
    • (2004) J Periodontol , vol.75 , pp. 249-259
    • Nukaga, J.1    Kobayashi, M.2    Shinki, T.3
  • 81
    • 0032854699 scopus 로고    scopus 로고
    • Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor: Receptor activator of NF-kappa B ligand
    • Udagawa N, Takahashi N, Jimi E, et al. Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor: receptor activator of NF-kappa B ligand. Bone 1999; 25: 517-23.
    • (1999) Bone , vol.25 , pp. 517-523
    • Udagawa, N.1    Takahashi, N.2    Jimi, E.3
  • 82
    • 33745138231 scopus 로고    scopus 로고
    • Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvarial bones
    • Swanson C, Lorentzon M, Conaway HH, Lerner UH. Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvarial bones. Endocrinology 2006; 147: 3613-22.
    • (2006) Endocrinology , vol.147 , pp. 3613-3622
    • Swanson, C.1    Lorentzon, M.2    Conaway, H.H.3    Lerner, U.H.4
  • 83
    • 33646808104 scopus 로고    scopus 로고
    • Wnt signalling in osteoblasts regulates expression of the receptor activator of NFkappaB ligand and inhibits osteoclastogenesis in vitro
    • Spencer GJ, Utting JC, Etheridge SL, Arnett TR, Genever PG. Wnt signalling in osteoblasts regulates expression of the receptor activator of NFkappaB ligand and inhibits osteoclastogenesis in vitro. J cell science 2006; 119: 1283-96.
    • (2006) J cell science , vol.119 , pp. 1283-1296
    • Spencer, G.J.1    Utting, J.C.2    Etheridge, S.L.3    Arnett, T.R.4    Genever, P.G.5
  • 85
    • 0037636046 scopus 로고    scopus 로고
    • Vitamin D3 supports osteoclastogenesis via functional vitamin D response element of human RANKL gene promoter
    • Kitazawa S, Kajimoto K, Kondo T, Kitazawa R. Vitamin D3 supports osteoclastogenesis via functional vitamin D response element of human RANKL gene promoter. J cellular Biochem 2003; 89: 771-7.
    • (2003) J cellular Biochem , vol.89 , pp. 771-777
    • Kitazawa, S.1    Kajimoto, K.2    Kondo, T.3    Kitazawa, R.4
  • 87
    • 0037073707 scopus 로고    scopus 로고
    • Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein
    • Fu Q, Jilka RL, Manolagas SC, O’Brien CA. Parathyroid hormone stimulates receptor activator of NFkappa B ligand and inhibits osteoprotegerin expression via protein kinase A activation of cAMP-response element-binding protein. J biological Chem 2002; 277: 48868-75.
    • (2002) J biological Chem , vol.277 , pp. 48868-48875
    • Fu, Q.1    Jilka, R.L.2    Manolagas, S.C.3    O’Brien, C.A.4
  • 88
    • 33846029473 scopus 로고    scopus 로고
    • Transcriptional control of receptor activator of nuclear factor-kappaB ligand by the protein kinase A activator forskolin and the transmembrane glycoprotein 130-activating cytokine, oncostatin M, is exerted through multiple distal enhancers
    • Kim S, Yamazaki M, Shevde NK, Pike JW. Transcriptional control of receptor activator of nuclear factor-kappaB ligand by the protein kinase A activator forskolin and the transmembrane glycoprotein 130-activating cytokine, oncostatin M, is exerted through multiple distal enhancers. Molecular Endocrinol 2007; 21: 197-214.
    • (2007) Molecular Endocrinol , vol.21 , pp. 197-214
    • Kim, S.1    Yamazaki, M.2    Shevde, N.K.3    Pike, J.W.4
  • 89
    • 0033516661 scopus 로고    scopus 로고
    • STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1, 2 5-dihydroxy vitamin D3 or parathyroid hormone
    • O’Brien CA, Gubrij I, Lin SC, Saylors RL, Manolagas SC. STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1, 2 5-dihydroxy vitamin D3 or parathyroid hormone. J Biological Chem 1999; 274: 19301-8.
    • (1999) J Biological Chem , vol.274 , pp. 19301-19308
    • O’Brien, C.A.1    Gubrij, I.2    Lin, S.C.3    Saylors, R.L.4    Manolagas, S.C.5
  • 90
    • 1642410788 scopus 로고    scopus 로고
    • Functional role for heat shock factors in the transcriptional regulation of human RANK ligand gene expression in stromal/osteoblast cells
    • Roccisana JL, Kawanabe N, Kajiya H, Koide M, Roodman GD, Reddy SV. Functional role for heat shock factors in the transcriptional regulation of human RANK ligand gene expression in stromal/osteoblast cells. J biological chemistry 2004; 279: 10500-7.
    • (2004) J biological chemistry , vol.279 , pp. 10500-10507
    • Roccisana, J.L.1    Kawanabe, N.2    Kajiya, H.3    Koide, M.4    Roodman, G.D.5    Reddy, S.V.6
  • 91
    • 0037135568 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone
    • Ishida A, Fujita N, Kitazawa R, Tsuruo T. Transforming growth factor-beta induces expression of receptor activator of NF-kappa B ligand in vascular endothelial cells derived from bone. J biological chemistry 2002; 277: 26217-24.
    • (2002) J biological chemistry , vol.277 , pp. 26217-26224
    • Ishida, A.1    Fujita, N.2    Kitazawa, R.3    Tsuruo, T.4
  • 92
    • 0642364978 scopus 로고    scopus 로고
    • RANKL regulates endothelial cell survival through the phosphatidylinositol 3’-kinase/Akt signal transduction pathway
    • Kim HH, Shin HS, Kwak HJ, et al. RANKL regulates endothelial cell survival through the phosphatidylinositol 3’-kinase/Akt signal transduction pathway. FASEB journal: official publication Federation Am Soc Exp Biol 2003; 17: 2163-5.
    • (2003) FASEB journal: Official publication Federation Am Soc Exp Biol , vol.17 , pp. 2163-2165
    • Kim, H.H.1    Shin, H.S.2    Kwak, H.J.3
  • 93
    • 0344441769 scopus 로고    scopus 로고
    • Bone marrow metastatic myeloma cells promote osteoclastogenesis through RANKL on endothelial cells
    • Okada T, Akikusa S, Okuno H, Kodaka M. Bone marrow metastatic myeloma cells promote osteoclastogenesis through RANKL on endothelial cells. Clinical Experimental Metastasis 2003; 20: 639-46.
    • (2003) Clinical Experimental Metastasis , vol.20 , pp. 639-646
    • Okada, T.1    Akikusa, S.2    Okuno, H.3    Kodaka, M.4
  • 94
    • 79958016522 scopus 로고    scopus 로고
    • Mouse Rankl expression is regulated in T cells by c-Fos through a cluster of distal regulatory enhancers designated the T cell control region
    • Bishop KA, Coy HM, Nerenz RD, Meyer MB, Pike JW. Mouse Rankl expression is regulated in T cells by c-Fos through a cluster of distal regulatory enhancers designated the T cell control region. J Biological Chem 2011; 286: 20880-91.
    • (2011) J Biological Chem , vol.286 , pp. 20880-20891
    • Bishop, K.A.1    Coy, H.M.2    Nerenz, R.D.3    Meyer, M.B.4    Pike, J.W.5
  • 95
    • 49049103008 scopus 로고    scopus 로고
    • IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model
    • Ju JH, Cho ML, Moon YM, et al. IL-23 induces receptor activator of NF-kappaB ligand expression on CD4+ T cells and promotes osteoclastogenesis in an autoimmune arthritis model. J Immunol 2008; 181: 1507-18.
    • (2008) J Immunol , vol.181 , pp. 1507-1518
    • Ju, J.H.1    Cho, M.L.2    Moon, Y.M.3
  • 96
    • 23644450623 scopus 로고    scopus 로고
    • RANK and RANKL expression as markers of dendritic cell-T cell interactions in paired samples of rheumatoid synovium and lymph nodes
    • Page G, Miossec P. RANK and RANKL expression as markers of dendritic cell-T cell interactions in paired samples of rheumatoid synovium and lymph nodes. Arthritis Rheum 2005; 52: 2307-12.
    • (2005) Arthritis Rheum , vol.52 , pp. 2307-2312
    • Page, G.1    Miossec, P.2
  • 97
    • 77956896044 scopus 로고    scopus 로고
    • PKA-induced receptor activator of NF-kappaB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification
    • Tseng W, Graham LS, Geng Y, et al. PKA-induced receptor activator of NF-kappaB ligand (RANKL) expression in vascular cells mediates osteoclastogenesis but not matrix calcification. J Biological Chem 2010; 285: 29925-31.
    • (2010) J Biological Chem , vol.285 , pp. 29925-29931
    • Tseng, W.1    Graham, L.S.2    Geng, Y.3
  • 98
    • 70449535539 scopus 로고    scopus 로고
    • Arterial stiffness and the autonomic nervous system during the development of Zucker diabetic fatty rats
    • Cosson E, Valensi P, Laude D, Mesangeau D, Dabire H. Arterial stiffness and the autonomic nervous system during the development of Zucker diabetic fatty rats. Diabetes Metabol 2009; 35: 364-70.
    • (2009) Diabetes Metabol , vol.35 , pp. 364-370
    • Cosson, E.1    Valensi, P.2    Laude, D.3    Mesangeau, D.4    Dabire, H.5
  • 99
    • 68749113916 scopus 로고    scopus 로고
    • cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models. Tissue engineering
    • Siddappa R, Mulder W, Steeghs I, et al. cAMP/PKA signaling inhibits osteogenic differentiation and bone formation in rodent models. Tissue engineering. Part A 2009; 15: 2135-43.
    • (2009) Part A , vol.15 , pp. 2135-2143
    • Siddappa, R.1    Mulder, W.2    Steeghs, I.3
  • 100
    • 49849084827 scopus 로고    scopus 로고
    • Redox control of endothelial function and dysfunction: Molecular mechanisms and therapeutic opportunities
    • Thomas SR, Witting PK, Drummond GR. Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. Antioxidants Redox Signaling 2008; 10: 1713-65.
    • (2008) Antioxidants Redox Signaling , vol.10 , pp. 1713-1765
    • Thomas, S.R.1    Witting, P.K.2    Drummond, G.R.3
  • 101
    • 47249157776 scopus 로고    scopus 로고
    • Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling
    • Byon CH, Javed A, Dai Q, et al. Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J Biological Chem 2008; 283: 15319-27.
    • (2008) J Biological Chem , vol.283 , pp. 15319-15327
    • Byon, C.H.1    Javed, A.2    Dai, Q.3
  • 102
    • 0036510762 scopus 로고    scopus 로고
    • TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells
    • Kim YM, Lee YM, Kim HS, Kim JD, Choi Y, Kim KW, Lee SY, Kwon YG. TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. J Biological Chem 2002; 277: 6799-805.
    • (2002) J Biological Chem , vol.277 , pp. 6799-6805
    • Kim, Y.M.1    Lee, Y.M.2    Kim, H.S.3    Kim, J.D.4    Choi, Y.5    Kim, K.W.6    Lee, S.Y.7    Kwon, Y.G.8
  • 103
    • 21244499298 scopus 로고    scopus 로고
    • TNF-related activation-induced cytokine enhances leukocyte adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF receptor-associated factor and protein kinase C-dependent NF-kappaB activation in endothelial cells
    • Min JK, Kim YM, Kim SW, et al. TNF-related activation-induced cytokine enhances leukocyte adhesiveness: induction of ICAM-1 and VCAM-1 via TNF receptor-associated factor and protein kinase C-dependent NF-kappaB activation in endothelial cells. J Immunol 2005; 175: 531-40.
    • (2005) J Immunol , vol.175 , pp. 531-540
    • Min, J.K.1    Kim, Y.M.2    Kim, S.W.3
  • 104
    • 33846925850 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: Impaired permeability and angiogenesis in eNOS-deficient mice
    • Min JK, Cho YL, Choi JH, et al. Receptor activator of nuclear factor (NF)-kappaB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice. Blood 2007; 109: 1495-502.
    • (2007) Blood , vol.109 , pp. 1495-1502
    • Min, J.K.1    Cho, Y.L.2    Choi, J.H.3
  • 105
    • 34047156083 scopus 로고    scopus 로고
    • TGF-beta and atherosclerosis in man
    • Grainger DJ. TGF-beta and atherosclerosis in man. Cardiovascular Research 2007; 74: 213-22.
    • (2007) Cardiovascular Research , vol.74 , pp. 213-222
    • Grainger, D.J.1
  • 107
    • 0033581952 scopus 로고    scopus 로고
    • Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
    • Kong YY, Feige U, Sarosi I, et al. Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand. Nature 1999; 402: 304-9.
    • (1999) Nature , vol.402 , pp. 304-309
    • Kong, Y.Y.1    Feige, U.2    Sarosi, I.3
  • 108
    • 0028972025 scopus 로고
    • 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma
    • Forman BM, Tontonoz P, Chen J, Brun RP, Spiegelman BM, Evans RM. 15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma. Cell 1995; 83: 803-12.
    • (1995) Cell , vol.83 , pp. 803-812
    • Forman, B.M.1    Tontonoz, P.2    Chen, J.3    Brun, R.P.4    Spiegelman, B.M.5    Evans, R.M.6
  • 109
    • 80053930190 scopus 로고    scopus 로고
    • 15-Deoxy-Delta(1)(2), (1) (4) prostaglandin J(2) reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice
    • Seno T, Hamaguchi M, Ashihara E, et al. 15-Deoxy-Delta(1)(2), (1) (4) prostaglandin J(2) reduces the formation of atherosclerotic lesions in apolipoprotein E knockout mice. PLoS One 2011; 6: e25541.
    • (2011) PLoS One , vol.6
    • Seno, T.1    Hamaguchi, M.2    Ashihara, E.3
  • 110
    • 33947665437 scopus 로고    scopus 로고
    • 15-deoxy-Delta12, 14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: Role of NF-kappaB and early growth response transcription factors
    • Fionda C, Nappi F, Piccoli M, Frati L, Santoni A, Cippitelli M. 15-deoxy-Delta12, 14-prostaglandin J2 negatively regulates rankl gene expression in activated T lymphocytes: role of NF-kappaB and early growth response transcription factors. J Immunol 2007; 178: 4039-50.
    • (2007) J Immunol , vol.178 , pp. 4039-4050
    • Fionda, C.1    Nappi, F.2    Piccoli, M.3    Frati, L.4    Santoni, A.5    Cippitelli, M.6
  • 111
    • 3142516035 scopus 로고    scopus 로고
    • Egr-1 is a major vascular pathogenic transcription factor in atherosclerosis and restenosis
    • Blaschke F, Bruemmer D, Law RE. Egr-1 is a major vascular pathogenic transcription factor in atherosclerosis and restenosis. Rev Endocrine Metabol Disorders 2004; 5: 249-54.
    • (2004) Rev Endocrine Metabol Disorders , vol.5 , pp. 249-254
    • Blaschke, F.1    Bruemmer, D.2    Law, R.E.3
  • 112
    • 0028173214 scopus 로고
    • c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling
    • Grigoriadis AE, Wang ZQ, Cecchini MG, et al. c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 1994; 266: 443-8.
    • (1994) Science , vol.266 , pp. 443-448
    • Grigoriadis, A.E.1    Wang, Z.Q.2    Cecchini, M.G.3
  • 113
    • 31344462096 scopus 로고    scopus 로고
    • Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells
    • Park HJ, Park OJ, Shin J. Receptor activator of NF-kappaB ligand enhances the activity of macrophages as antigen presenting cells. Exp Mol Med 2005; 37: 524-32.
    • (2005) Exp Mol Med , vol.37 , pp. 524-532
    • Park, H.J.1    Park, O.J.2    Shin, J.3


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