RANK and RANKL expression as markers of dendritic cell-T cell interactions in paired samples of rheumatoid synovium and lymph nodes

Arthritis and Rheumatism

Volumn 52, Issue 8, 2005, Pages 2307-2312

  Page, Guillaume ^a   Miossec, Pierre ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1BETA; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; T6 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BONE DESTRUCTION; CELL INTERACTION; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNITY; IMMUNOHISTOCHEMISTRY; LYMPH NODE; LYMPHOCYTIC INFILTRATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; T LYMPHOCYTE SUBPOPULATION;

ARTHRITIS, RHEUMATOID; BIOLOGICAL MARKERS; CARRIER PROTEINS; CELL COMMUNICATION; CELLS, CULTURED; DENDRITIC CELLS; HUMANS; INTERLEUKIN-1; INTERLEUKIN-17; LYMPH NODES; MEMBRANE GLYCOPROTEINS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; SYNOVIAL MEMBRANE; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 23644450623     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21211     Document Type: Article

References (15)

1. Gravallese EM. Bone destruction in arthritis. Ann Rheum Dis 2002;61 Suppl 2:ii84-6.
2. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, Burgess T, et al. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 1998;93:165-76.
3. Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999;397: 315-23.
4. Anderson DM, Maraskovsky E, Billingsley WL, Dougall WC, Tometsko ME, Roux ER, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997;390:175-9.
5. Dougall WC, Glaccum M, Charrier K, Rohrhach K, Brasel K, de Smedt T, et al. RANK is essential for osteoclast and lymph node development. Genes Dev 1999;13:2412-24.
6. Page G, Miossee P. Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression. J Pathol 2004;204:28-38.
7. Ropes MW, Bennett GA, Cohb S, Jacox R, Jessar RA. 1958 revision of diagnostic criteria for rheumatoid arthritis. Bull Rheum Dis 1958;9:175-6.
8. Page G, Lebecque S, Miossee P. Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: correlation with selective chemokine expression in rheumatoid synovium. J Immunol 2002;168:5333-41.
9. Granet C, Maslinski W, Miossee P. Increased AP-1 and NF-κB activation and recruitment with the combination of the proinflammatory cytokines IL-1β, tumor necrosis factor α and IL-17 in rheumatoid synoviocytes. Arthritis Res Ther 2004;6:R190-8.
10. Gravallese EM, Manning C, Tsay A, Naito A, Pan C, Amento E, et al. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum 2000;43:250-8.
11. Crotti TN, Smith MD, Weedon H, Ahern MJ, Findlay DM, Kraan M, et al. Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients: semi-quantitative and quantitative analysis. Ann Rheum Dis 2002;61: 1047-54.
12. Haynes DR, Barg E, Crotti TN, Holding C, Weedon H, Atkins GJ, et al. Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls. Rheumatology (Oxford) 2003;42:123-34.
13. Kotake S, Udagawa N, Hakoda M, Mogi M, Yano K, Tsuda E, et al. Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum 2001;44: 1003-12.
14. Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, et al. Involvement of receptor activator of nuclear factor κB ligand/osteoclast differentiation factor in osteoclasto-genesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000;43:259-69.
15. Chabaud M, Miossee P. The combination of tumor necrosis factor α blockade with interleukin-1 and interleukin-17 blockade is more effective for controlling synovial inflammation and bone resorption in an ex vivo model. Arthritis Rheum 2001;44:1293-303.