메뉴 건너뛰기




Volumn 3, Issue 6, 2014, Pages 389-402

Developing stratified epithelia: Lessons from the epidermis and thymus

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; BETA CATENIN; BONE MORPHOGENETIC PROTEIN; CYTOKERATIN 14; CYTOKERATIN 18; CYTOKERATIN 8; EPHRIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 10; FILAGGRIN; HISTONE DEMETHYLASE; INTERLEUKIN 15; KERATINOCYTE GROWTH FACTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LYMPHOID ENHANCER FACTOR 1; NOTCH RECEPTOR; PAIRED BOX TRANSCRIPTION FACTOR; PROTEIN P107; PROTEIN P130; PROTEIN P53; PROTEIN P63; T BOX TRANSCRIPTION FACTOR; TESTIS DETERMINING FACTOR; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR PAX9; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

EID: 84911464247     PISSN: 17597684     EISSN: 17597692     Source Type: Journal    
DOI: 10.1002/wdev.146     Document Type: Review
Times cited : (25)

References (139)
  • 1
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: a balancing act of stem cells in the skin
    • Blanpain C, Fuchs E. Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 2009, 10:207-217.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 2
    • 38449101897 scopus 로고    scopus 로고
    • Mechanisms regulating epithelial stratification
    • Koster MI, Roop DR. Mechanisms regulating epithelial stratification. Annu Rev Cell Dev Biol 2007, 23:93-113.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 93-113
    • Koster, M.I.1    Roop, D.R.2
  • 3
    • 0037406396 scopus 로고    scopus 로고
    • Epidermal basement membrane zone components: ultrastructural distribution and molecular interactions
    • McMillan JR, Akiyama M, Shimizu H. Epidermal basement membrane zone components: ultrastructural distribution and molecular interactions. J Dermatol Sci 2003, 31:169-177.
    • (2003) J Dermatol Sci , vol.31 , pp. 169-177
    • McMillan, J.R.1    Akiyama, M.2    Shimizu, H.3
  • 4
    • 37149020758 scopus 로고    scopus 로고
    • Transcriptional control of the differentiation program of interfollicular epidermal keratinocytes
    • Nagarajan P, Romano RA, Sinha S. Transcriptional control of the differentiation program of interfollicular epidermal keratinocytes. Crit Rev Eukaryot Gene Expr 2008, 18:57-79.
    • (2008) Crit Rev Eukaryot Gene Expr , vol.18 , pp. 57-79
    • Nagarajan, P.1    Romano, R.A.2    Sinha, S.3
  • 6
    • 33645047906 scopus 로고    scopus 로고
    • Establishment and functioning of intrathymic microenvironments
    • Anderson G et al. Establishment and functioning of intrathymic microenvironments. Immunol Rev 2006, 209:10-27.
    • (2006) Immunol Rev , vol.209 , pp. 10-27
    • Anderson, G.1
  • 7
    • 42649138855 scopus 로고    scopus 로고
    • Thymus organogenesis
    • Rodewald HR. Thymus organogenesis. Annu Rev Immunol 2008, 26:355-388.
    • (2008) Annu Rev Immunol , vol.26 , pp. 355-388
    • Rodewald, H.R.1
  • 8
    • 84892472653 scopus 로고    scopus 로고
    • Serial progression of cortical and medullary thymic epithelial microenvironments
    • Alves NL et al. Serial progression of cortical and medullary thymic epithelial microenvironments. Eur J Immunol 2014, 44:16-22.
    • (2014) Eur J Immunol , vol.44 , pp. 16-22
    • Alves, N.L.1
  • 9
    • 43949165426 scopus 로고
    • The thymic microenvironment
    • Boyd RL et al. The thymic microenvironment. Immunol Today 1993, 14:445-459.
    • (1993) Immunol Today , vol.14 , pp. 445-459
    • Boyd, R.L.1
  • 10
    • 33644845679 scopus 로고    scopus 로고
    • Journey through the thymus: stromal guides for T-cell development and selection
    • Takahama Y. Journey through the thymus: stromal guides for T-cell development and selection. Nat Rev Immunol 2006, 6:127-135.
    • (2006) Nat Rev Immunol , vol.6 , pp. 127-135
    • Takahama, Y.1
  • 11
    • 84940625395 scopus 로고
    • Identification of filaggrin in Hassall's corpuscle by histochemical and immunohistochemical methods
    • Favre A. Identification of filaggrin in Hassall's corpuscle by histochemical and immunohistochemical methods. Acta Anat 1989, 135:71-76.
    • (1989) Acta Anat , vol.135 , pp. 71-76
    • Favre, A.1
  • 12
    • 0346103716 scopus 로고    scopus 로고
    • Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus
    • Hale LP, Markert ML. Corticosteroids regulate epithelial cell differentiation and Hassall body formation in the human thymus. J Immunol 2004, 172:617-624.
    • (2004) J Immunol , vol.172 , pp. 617-624
    • Hale, L.P.1    Markert, M.L.2
  • 13
    • 0028954846 scopus 로고
    • Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes
    • Patel DD, Whichard LP, Radcliff G, Denning SM, Haynes BF. Characterization of human thymic epithelial cell surface antigens: phenotypic similarity of thymic epithelial cells to epidermal keratinocytes. J Clin Immunol 1995, 15:80-92.
    • (1995) J Clin Immunol , vol.15 , pp. 80-92
    • Patel, D.D.1    Whichard, L.P.2    Radcliff, G.3    Denning, S.M.4    Haynes, B.F.5
  • 14
    • 0023113652 scopus 로고
    • Ontogeny of the human thymus during fetal development
    • Lobach DF, Haynes BF. Ontogeny of the human thymus during fetal development. J Clin Immunol 1987, 7:81-97.
    • (1987) J Clin Immunol , vol.7 , pp. 81-97
    • Lobach, D.F.1    Haynes, B.F.2
  • 15
    • 77955902048 scopus 로고    scopus 로고
    • Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells
    • Bonfanti P et al. Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells. Nature 2010, 466:978-982.
    • (2010) Nature , vol.466 , pp. 978-982
    • Bonfanti, P.1
  • 16
    • 77954943215 scopus 로고    scopus 로고
    • Epithelial decision makers: in search of the 'epimmunome'
    • Swamy M, Jamora C, Havran W, Hayday A. Epithelial decision makers: in search of the 'epimmunome'. Nat Immunol 2010, 11:656-665.
    • (2010) Nat Immunol , vol.11 , pp. 656-665
    • Swamy, M.1    Jamora, C.2    Havran, W.3    Hayday, A.4
  • 17
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • Gasser S, Orsulic S, Brown EJ, Raulet DH. The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 2005, 436:1186-1190.
    • (2005) Nature , vol.436 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 18
    • 65249157251 scopus 로고    scopus 로고
    • Costimulation of dendritic epidermal γδ T cells by a new NKG2D ligand expressed specifically in the skin
    • Whang MI, Guerra N, Raulet DH. Costimulation of dendritic epidermal γδ T cells by a new NKG2D ligand expressed specifically in the skin. J Immunol 2009, 182:4557-4564.
    • (2009) J Immunol , vol.182 , pp. 4557-4564
    • Whang, M.I.1    Guerra, N.2    Raulet, D.H.3
  • 19
    • 68649104004 scopus 로고    scopus 로고
    • γδ T cells and the lymphoid stress-surveillance response
    • Hayday AC. γδ T cells and the lymphoid stress-surveillance response. Immunity 2009, 31:184-196.
    • (2009) Immunity , vol.31 , pp. 184-196
    • Hayday, A.C.1
  • 20
    • 84888008030 scopus 로고    scopus 로고
    • The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin
    • Mackay LK et al. The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin. Nat Immunol 2013, 14:1294-1301.
    • (2013) Nat Immunol , vol.14 , pp. 1294-1301
    • Mackay, L.K.1
  • 22
    • 0032547830 scopus 로고    scopus 로고
    • Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development
    • McGowan KM, Coulombe PA. Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol 1998, 143:469-486.
    • (1998) J Cell Biol , vol.143 , pp. 469-486
    • McGowan, K.M.1    Coulombe, P.A.2
  • 23
    • 84883236090 scopus 로고    scopus 로고
    • Notch signaling represses p63 expression in the developing surface ectoderm
    • Tadeu AM, Horsley V. Notch signaling represses p63 expression in the developing surface ectoderm. Development 2013, 140:3777-3786.
    • (2013) Development , vol.140 , pp. 3777-3786
    • Tadeu, A.M.1    Horsley, V.2
  • 24
    • 0024232731 scopus 로고
    • Development and morphology of the periderm of mouse embryos (days 9-12 of gestation)
    • M'Boneko V, Merker HJ. Development and morphology of the periderm of mouse embryos (days 9-12 of gestation). Acta Anat 1988, 133:325-336.
    • (1988) Acta Anat , vol.133 , pp. 325-336
    • M'Boneko, V.1    Merker, H.J.2
  • 25
    • 0031865846 scopus 로고    scopus 로고
    • Patterned acquisition of skin barrier function during development
    • Hardman MJ, Sisi P, Banbury DN, Byrne C. Patterned acquisition of skin barrier function during development. Development 1998, 125:1541-1552.
    • (1998) Development , vol.125 , pp. 1541-1552
    • Hardman, M.J.1    Sisi, P.2    Banbury, D.N.3    Byrne, C.4
  • 26
    • 0028025616 scopus 로고
    • Programming gene expression in developing epidermis
    • Byrne C, Tainsky M, Fuchs E. Programming gene expression in developing epidermis. Development 1994, 120:2369-2383.
    • (1994) Development , vol.120 , pp. 2369-2383
    • Byrne, C.1    Tainsky, M.2    Fuchs, E.3
  • 27
    • 24644494270 scopus 로고    scopus 로고
    • Asymmetric cell divisions promote stratification and differentiation of mammalian skin
    • Lechler T, Fuchs E. Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature 2005, 437:275-280.
    • (2005) Nature , vol.437 , pp. 275-280
    • Lechler, T.1    Fuchs, E.2
  • 28
    • 0028267922 scopus 로고
    • Protein composition of cornified cell envelopes of epidermal keratinocytes
    • Steven AC, Steinert PM. Protein composition of cornified cell envelopes of epidermal keratinocytes. J Cell Sci 1994, 107(Pt 2):693-700.
    • (1994) J Cell Sci , vol.107 , pp. 693-700
    • Steven, A.C.1    Steinert, P.M.2
  • 30
    • 70449729939 scopus 로고    scopus 로고
    • Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis
    • Van Keymeulen A et al. Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol 2009, 187:91-100.
    • (2009) J Cell Biol , vol.187 , pp. 91-100
    • Van Keymeulen, A.1
  • 34
    • 84880330419 scopus 로고    scopus 로고
    • Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells
    • Bardot ES et al. Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells. EMBO J 2013, 32:1990-2000.
    • (2013) EMBO J , vol.32 , pp. 1990-2000
    • Bardot, E.S.1
  • 35
    • 44749091499 scopus 로고    scopus 로고
    • Thymus development and function
    • Boehm T. Thymus development and function. Curr Opin Immunol 2008, 20:178-184.
    • (2008) Curr Opin Immunol , vol.20 , pp. 178-184
    • Boehm, T.1
  • 36
    • 0028000121 scopus 로고
    • New member of the winged-helix protein family disrupted in mouse and rat nude mutations
    • Nehls M, Pfeifer D, Schorpp M, Hedrich H, Boehm T. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature 1994, 372:103-107.
    • (1994) Nature , vol.372 , pp. 103-107
    • Nehls, M.1    Pfeifer, D.2    Schorpp, M.3    Hedrich, H.4    Boehm, T.5
  • 37
    • 0029920145 scopus 로고    scopus 로고
    • Two genetically separable steps in the differentiation of thymic epithelium
    • Nehls M et al. Two genetically separable steps in the differentiation of thymic epithelium. Science 1996, 272:886-889.
    • (1996) Science , vol.272 , pp. 886-889
    • Nehls, M.1
  • 38
    • 0034644149 scopus 로고    scopus 로고
    • Genetic ablation of parathyroid glands reveals another source of parathyroid hormone
    • Gunther T et al. Genetic ablation of parathyroid glands reveals another source of parathyroid hormone. Nature 2000, 406:199-203.
    • (2000) Nature , vol.406 , pp. 199-203
    • Gunther, T.1
  • 39
    • 0035496231 scopus 로고    scopus 로고
    • Lymphostromal interactions in thymic development and function
    • Anderson G, Jenkinson EJ. Lymphostromal interactions in thymic development and function. Nat Rev Immunol 2001, 1:31-40.
    • (2001) Nat Rev Immunol , vol.1 , pp. 31-40
    • Anderson, G.1    Jenkinson, E.J.2
  • 40
    • 33645091616 scopus 로고    scopus 로고
    • Cellular and molecular events during early thymus development
    • Hollander G et al. Cellular and molecular events during early thymus development. Immunol Rev 2006, 209:28-46.
    • (2006) Immunol Rev , vol.209 , pp. 28-46
    • Hollander, G.1
  • 41
    • 34548798748 scopus 로고    scopus 로고
    • Redefining epithelial progenitor potential in the developing thymus
    • Rossi SW et al. Redefining epithelial progenitor potential in the developing thymus. Eur J Immunol 2007, 37:2411-2418.
    • (2007) Eur J Immunol , vol.37 , pp. 2411-2418
    • Rossi, S.W.1
  • 42
    • 33745532385 scopus 로고    scopus 로고
    • Formation of a functional thymus initiated by a postnatal epithelial progenitor cell
    • Bleul CC et al. Formation of a functional thymus initiated by a postnatal epithelial progenitor cell. Nature 2006, 441:992-996.
    • (2006) Nature , vol.441 , pp. 992-996
    • Bleul, C.C.1
  • 43
    • 33745516115 scopus 로고    scopus 로고
    • Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium
    • Rossi SW, Jenkinson WE, Anderson G, Jenkinson EJ. Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature 2006, 441:988-991.
    • (2006) Nature , vol.441 , pp. 988-991
    • Rossi, S.W.1    Jenkinson, W.E.2    Anderson, G.3    Jenkinson, E.J.4
  • 44
    • 0036063262 scopus 로고    scopus 로고
    • Identification and characterization of thymic epithelial progenitor cells
    • Bennett AR et al. Identification and characterization of thymic epithelial progenitor cells. Immunity 2002, 16:803-814.
    • (2002) Immunity , vol.16 , pp. 803-814
    • Bennett, A.R.1
  • 45
    • 0035856960 scopus 로고    scopus 로고
    • Thymus medulla consisting of epithelial islets each derived from a single progenitor
    • Rodewald HR, Paul S, Haller C, Bluethmann H, Blum C. Thymus medulla consisting of epithelial islets each derived from a single progenitor. Nature 2001, 414:763-768.
    • (2001) Nature , vol.414 , pp. 763-768
    • Rodewald, H.R.1    Paul, S.2    Haller, C.3    Bluethmann, H.4    Blum, C.5
  • 46
    • 14844303460 scopus 로고    scopus 로고
    • Controlling the thymic microenvironment
    • Gray DH et al. Controlling the thymic microenvironment. Curr Opin Immunol 2005, 17:137-143.
    • (2005) Curr Opin Immunol , vol.17 , pp. 137-143
    • Gray, D.H.1
  • 47
    • 0032578456 scopus 로고    scopus 로고
    • Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment
    • Klug DB et al. Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci USA 1998, 95:11822-11827.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11822-11827
    • Klug, D.B.1
  • 48
    • 0036305567 scopus 로고    scopus 로고
    • Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells
    • Gill J, Malin M, Hollander GA, Boyd R. Generation of a complete thymic microenvironment by MTS24(+) thymic epithelial cells. Nat Immunol 2002, 3:635-642.
    • (2002) Nat Immunol , vol.3 , pp. 635-642
    • Gill, J.1    Malin, M.2    Hollander, G.A.3    Boyd, R.4
  • 49
    • 84874962972 scopus 로고    scopus 로고
    • Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors
    • Baik S, Jenkinson EJ, Lane PJ, Anderson G, Jenkinson WE. Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors. Eur J Immunol 2013, 43:589-594.
    • (2013) Eur J Immunol , vol.43 , pp. 589-594
    • Baik, S.1    Jenkinson, E.J.2    Lane, P.J.3    Anderson, G.4    Jenkinson, W.E.5
  • 50
  • 51
    • 35748941369 scopus 로고    scopus 로고
    • Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
    • Gray D, Abramson J, Benoist C, Mathis D. Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. J Exp Med 2007, 204:2521-2528.
    • (2007) J Exp Med , vol.204 , pp. 2521-2528
    • Gray, D.1    Abramson, J.2    Benoist, C.3    Mathis, D.4
  • 52
    • 70349556314 scopus 로고    scopus 로고
    • Thymic epithelial cells: the multi-tasking framework of the T cell "cradle"
    • Alves NL, Huntington ND, Rodewald HR, Di Santo JP. Thymic epithelial cells: the multi-tasking framework of the T cell "cradle". Trends Immunol 2009, 30:468-474.
    • (2009) Trends Immunol , vol.30 , pp. 468-474
    • Alves, N.L.1    Huntington, N.D.2    Rodewald, H.R.3    Di Santo, J.P.4
  • 53
    • 84886430543 scopus 로고    scopus 로고
    • TGF-β type II receptor expression in thymic epithelial cells inhibits the development of Hassall's corpuscles in mice
    • Odaka C et al. TGF-β type II receptor expression in thymic epithelial cells inhibits the development of Hassall's corpuscles in mice. Int Immunol 2013, 25:633-642.
    • (2013) Int Immunol , vol.25 , pp. 633-642
    • Odaka, C.1
  • 54
    • 62149122634 scopus 로고    scopus 로고
    • Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
    • Ezhkova E et al. Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 2009, 136:1122-1135.
    • (2009) Cell , vol.136 , pp. 1122-1135
    • Ezhkova, E.1
  • 55
    • 47549105128 scopus 로고    scopus 로고
    • Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
    • Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes Dev 2008, 22:1865-1870.
    • (2008) Genes Dev , vol.22 , pp. 1865-1870
    • Sen, G.L.1    Webster, D.E.2    Barragan, D.I.3    Chang, H.Y.4    Khavari, P.A.5
  • 56
    • 84898474685 scopus 로고    scopus 로고
    • Early inductive events in ectodermal appendage morphogenesis
    • Biggs LC, Mikkola ML. Early inductive events in ectodermal appendage morphogenesis. Semin Cell Dev Biol 2014, 25-26:11-21.
    • (2014) Semin Cell Dev Biol , vol.25-26 , pp. 11-21
    • Biggs, L.C.1    Mikkola, M.L.2
  • 58
    • 85028111221 scopus 로고    scopus 로고
    • Epithelial stem cells and the development of the thymus, parathyroid, and skin
    • Vemuri MC, Rajasekhar VK, eds. Springer Science and Business Media: Humana Press
    • Chew-Li Soh JMC, Richard LB, Chidgey AP. Epithelial stem cells and the development of the thymus, parathyroid, and skin. In: Vemuri MC, Rajasekhar VK, eds. Stem Cell Biology and Regenerative Medicine. Springer Science and Business Media: Humana Press; 2009, 405-437.
    • (2009) Stem Cell Biology and Regenerative Medicine , pp. 405-437
    • Chew-Li Soh, J.M.C.1    Richard, L.B.2    Chidgey, A.P.3
  • 59
    • 0347994904 scopus 로고    scopus 로고
    • Marker succession during the development of keratinocytes from cultured human embryonic stem cells
    • Green H, Easley K, Iuchi S. Marker succession during the development of keratinocytes from cultured human embryonic stem cells. Proc Natl Acad Sci USA 2003, 100:15625-15630.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15625-15630
    • Green, H.1    Easley, K.2    Iuchi, S.3
  • 60
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 2007, 129:523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 61
    • 29144524913 scopus 로고    scopus 로고
    • TAp63α induces AP-2γ as an early event in epidermal morphogenesis
    • Koster MI, Kim S, Huang J, Williams T, Roop DR. TAp63α induces AP-2γ as an early event in epidermal morphogenesis. Dev Biol 2006, 289:253-261.
    • (2006) Dev Biol , vol.289 , pp. 253-261
    • Koster, M.I.1    Kim, S.2    Huang, J.3    Williams, T.4    Roop, D.R.5
  • 62
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA et al. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999, 398:708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1
  • 63
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999, 398:714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1
  • 64
    • 67649159970 scopus 로고    scopus 로고
    • TAp63 prevents premature aging by promoting adult stem cell maintenance
    • Su X et al. TAp63 prevents premature aging by promoting adult stem cell maintenance. Cell Stem Cell 2009, 5:64-75.
    • (2009) Cell Stem Cell , vol.5 , pp. 64-75
    • Su, X.1
  • 65
    • 84856188471 scopus 로고    scopus 로고
    • δNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation
    • Romano RA et al. δNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development 2012, 139:772-782.
    • (2012) Development , vol.139 , pp. 772-782
    • Romano, R.A.1
  • 66
    • 34247252481 scopus 로고    scopus 로고
    • A functional enhancer of keratin14 is a direct transcriptional target of δNp63
    • Romano RA, Birkaya B, Sinha S. A functional enhancer of keratin14 is a direct transcriptional target of δNp63. J Invest Dermatol 2007, 127:1175-1186.
    • (2007) J Invest Dermatol , vol.127 , pp. 1175-1186
    • Romano, R.A.1    Birkaya, B.2    Sinha, S.3
  • 67
    • 34547513872 scopus 로고    scopus 로고
    • δNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2
    • Candi E et al. δNp63 regulates thymic development through enhanced expression of FgfR2 and Jag2. Proc Natl Acad Sci USA 2007, 104:11999-12004.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11999-12004
    • Candi, E.1
  • 68
    • 84863229693 scopus 로고    scopus 로고
    • Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome
    • Ferone G et al. Mutant p63 causes defective expansion of ectodermal progenitor cells and impaired FGF signalling in AEC syndrome. EMBO Mol Med 2012, 4:192-205.
    • (2012) EMBO Mol Med , vol.4 , pp. 192-205
    • Ferone, G.1
  • 69
    • 85047690938 scopus 로고    scopus 로고
    • Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate
    • Rice R et al. Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest 2004, 113:1692-1700.
    • (2004) J Clin Invest , vol.113 , pp. 1692-1700
    • Rice, R.1
  • 70
    • 0035881543 scopus 로고    scopus 로고
    • Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb
    • Revest JM, Suniara RK, Kerr K, Owen JJ, Dickson C. Development of the thymus requires signaling through the fibroblast growth factor receptor R2-IIIb. J Immunol 2001, 167:1954-1961.
    • (2001) J Immunol , vol.167 , pp. 1954-1961
    • Revest, J.M.1    Suniara, R.K.2    Kerr, K.3    Owen, J.J.4    Dickson, C.5
  • 71
    • 33646711244 scopus 로고    scopus 로고
    • p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
    • Laurikkala J et al. p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development 2006, 133:1553-1563.
    • (2006) Development , vol.133 , pp. 1553-1563
    • Laurikkala, J.1
  • 73
    • 0036239671 scopus 로고    scopus 로고
    • Complete rescue of the nude mutant phenotype by a wild-type Foxn1 transgene
    • Cunliffe VT, Furley AJ, Keenan D. Complete rescue of the nude mutant phenotype by a wild-type Foxn1 transgene. Mamm Genome 2002, 13:245-252.
    • (2002) Mamm Genome , vol.13 , pp. 245-252
    • Cunliffe, V.T.1    Furley, A.J.2    Keenan, D.3
  • 74
    • 0029838175 scopus 로고    scopus 로고
    • The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation
    • Brissette JL, Li J, Kamimura J, Lee D, Dotto GP. The product of the mouse nude locus, Whn, regulates the balance between epithelial cell growth and differentiation. Genes Dev 1996, 10:2212-2221.
    • (1996) Genes Dev , vol.10 , pp. 2212-2221
    • Brissette, J.L.1    Li, J.2    Kamimura, J.3    Lee, D.4    Dotto, G.P.5
  • 75
    • 0036174684 scopus 로고    scopus 로고
    • Role of the nude gene in epithelial terminal differentiation
    • Baxter RM, Brissette JL. Role of the nude gene in epithelial terminal differentiation. J Invest Dermatol 2002, 118:303-309.
    • (2002) J Invest Dermatol , vol.118 , pp. 303-309
    • Baxter, R.M.1    Brissette, J.L.2
  • 76
    • 59849123625 scopus 로고    scopus 로고
    • Checkpoints in the development of thymic cortical epithelial cells
    • Shakib S et al. Checkpoints in the development of thymic cortical epithelial cells. J Immunol 2009, 182:130-137.
    • (2009) J Immunol , vol.182 , pp. 130-137
    • Shakib, S.1
  • 77
    • 38449106709 scopus 로고    scopus 로고
    • The thymus as an inductive site for T lymphopoiesis
    • Ciofani M, Zuniga-Pflucker JC. The thymus as an inductive site for T lymphopoiesis. Annu Rev Cell Dev Biol 2007, 23:463-493.
    • (2007) Annu Rev Cell Dev Biol , vol.23 , pp. 463-493
    • Ciofani, M.1    Zuniga-Pflucker, J.C.2
  • 78
    • 84880646691 scopus 로고    scopus 로고
    • Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression
    • Garfin PM et al. Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. J Exp Med 2013, 210:1087-1097.
    • (2013) J Exp Med , vol.210 , pp. 1087-1097
    • Garfin, P.M.1
  • 79
    • 84883660958 scopus 로고    scopus 로고
    • FOXN1: a master regulator gene of thymic epithelial development program
    • Romano R et al. FOXN1: a master regulator gene of thymic epithelial development program. Front Immunol 2013, 4:187.
    • (2013) Front Immunol , vol.4 , pp. 187
    • Romano, R.1
  • 80
    • 0036237355 scopus 로고    scopus 로고
    • Thymopoiesis requires Pax9 function in thymic epithelial cells
    • Hetzer-Egger C et al. Thymopoiesis requires Pax9 function in thymic epithelial cells. Eur J Immunol 2002, 32:1175-1181.
    • (2002) Eur J Immunol , vol.32 , pp. 1175-1181
    • Hetzer-Egger, C.1
  • 81
    • 0035881214 scopus 로고    scopus 로고
    • Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis
    • Su D, Ellis S, Napier A, Lee K, Manley NR. Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Dev Biol 2001, 236:316-329.
    • (2001) Dev Biol , vol.236 , pp. 316-329
    • Su, D.1    Ellis, S.2    Napier, A.3    Lee, K.4    Manley, N.R.5
  • 82
    • 0029030722 scopus 로고
    • The role of Hoxa-3 in mouse thymus and thyroid development
    • Manley NR, Capecchi MR. The role of Hoxa-3 in mouse thymus and thyroid development. Development 1995, 121:1989-2003.
    • (1995) Development , vol.121 , pp. 1989-2003
    • Manley, N.R.1    Capecchi, M.R.2
  • 83
    • 21644472188 scopus 로고    scopus 로고
    • HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair
    • Mace KA, Hansen SL, Myers C, Young DM, Boudreau N. HOXA3 induces cell migration in endothelial and epithelial cells promoting angiogenesis and wound repair. J Cell Sci 2005, 118:2567-2577.
    • (2005) J Cell Sci , vol.118 , pp. 2567-2577
    • Mace, K.A.1    Hansen, S.L.2    Myers, C.3    Young, D.M.4    Boudreau, N.5
  • 84
    • 3042813439 scopus 로고    scopus 로고
    • Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis
    • Ruiz S et al. Unique and overlapping functions of pRb and p107 in the control of proliferation and differentiation in epidermis. Development 2004, 131:2737-2748.
    • (2004) Development , vol.131 , pp. 2737-2748
    • Ruiz, S.1
  • 85
    • 60249092412 scopus 로고    scopus 로고
    • Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner
    • Chen L, Xiao S, Manley NR. Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner. Blood 2009, 113:567-574.
    • (2009) Blood , vol.113 , pp. 567-574
    • Chen, L.1    Xiao, S.2    Manley, N.R.3
  • 86
    • 77949312399 scopus 로고    scopus 로고
    • Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy
    • Cheng L et al. Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy. J Biol Chem 2010, 285:5836-5847.
    • (2010) J Biol Chem , vol.285 , pp. 5836-5847
    • Cheng, L.1
  • 87
    • 84860508493 scopus 로고    scopus 로고
    • An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration
    • Chen T et al. An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration. Nature 2012, 485:104-108.
    • (2012) Nature , vol.485 , pp. 104-108
    • Chen, T.1
  • 88
    • 0342658137 scopus 로고    scopus 로고
    • Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development
    • Chapman DL et al. Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev Dyn 1996, 206:379-390.
    • (1996) Dev Dyn , vol.206 , pp. 379-390
    • Chapman, D.L.1
  • 89
    • 0035098557 scopus 로고    scopus 로고
    • DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
    • Jerome LA, Papaioannou VE. DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1. Nat Genet 2001, 27:286-291.
    • (2001) Nat Genet , vol.27 , pp. 286-291
    • Jerome, L.A.1    Papaioannou, V.E.2
  • 90
    • 0037389229 scopus 로고    scopus 로고
    • T-box genes in human disorders
    • Packham EA, Brook JD. T-box genes in human disorders. Hum Mol Genet 2003, 12 Spec No 1:R37-44.
    • (2003) Hum Mol Genet , vol.12 SPEC. NO. 1 , pp. R37-R44
    • Packham, E.A.1    Brook, J.D.2
  • 91
    • 0035263599 scopus 로고    scopus 로고
    • Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice
    • Lindsay EA et al. Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice. Nature 2001, 410:97-101.
    • (2001) Nature , vol.410 , pp. 97-101
    • Lindsay, E.A.1
  • 93
    • 0036797067 scopus 로고    scopus 로고
    • A genetic link between Tbx1 and fibroblast growth factor signaling
    • Vitelli F et al. A genetic link between Tbx1 and fibroblast growth factor signaling. Development 2002, 129:4605-4611.
    • (2002) Development , vol.129 , pp. 4605-4611
    • Vitelli, F.1
  • 94
    • 25844503071 scopus 로고    scopus 로고
    • Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1
    • Ivins S et al. Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking Tbx1. Dev Biol 2005, 285:554-569.
    • (2005) Dev Biol , vol.285 , pp. 554-569
    • Ivins, S.1
  • 95
    • 0033961133 scopus 로고    scopus 로고
    • An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
    • De Moerlooze L et al. An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development 2000, 127:483-492.
    • (2000) Development , vol.127 , pp. 483-492
    • De Moerlooze, L.1
  • 96
    • 0344445675 scopus 로고    scopus 로고
    • A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning
    • Petiot A et al. A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development 2003, 130:5493-5501.
    • (2003) Development , vol.130 , pp. 5493-5501
    • Petiot, A.1
  • 97
    • 67651057006 scopus 로고    scopus 로고
    • KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin
    • Richardson GD et al. KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development 2009, 136:2153-2164.
    • (2009) Development , vol.136 , pp. 2153-2164
    • Richardson, G.D.1
  • 99
    • 22344441322 scopus 로고    scopus 로고
    • Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells
    • Lowry WE et al. Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells. Genes Dev 2005, 19:1596-1611.
    • (2005) Genes Dev , vol.19 , pp. 1596-1611
    • Lowry, W.E.1
  • 100
    • 84890076086 scopus 로고    scopus 로고
    • Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis
    • Choi YS et al. Distinct functions for Wnt/β-catenin in hair follicle stem cell proliferation and survival and interfollicular epidermal homeostasis. Cell Stem Cell 2013, 13:720-733.
    • (2013) Cell Stem Cell , vol.13 , pp. 720-733
    • Choi, Y.S.1
  • 101
    • 84889242647 scopus 로고    scopus 로고
    • Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling
    • Lim X et al. Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. Science 2013, 342:1226-1230.
    • (2013) Science , vol.342 , pp. 1226-1230
    • Lim, X.1
  • 102
    • 0035902074 scopus 로고    scopus 로고
    • The status of Wnt signalling regulates neural and epidermal fates in the chick embryo
    • Wilson SI et al. The status of Wnt signalling regulates neural and epidermal fates in the chick embryo. Nature 2001, 411:325-330.
    • (2001) Nature , vol.411 , pp. 325-330
    • Wilson, S.I.1
  • 103
    • 0036113510 scopus 로고    scopus 로고
    • WNT signals are required for the initiation of hair follicle development
    • Andl T, Reddy ST, Gaddapara T, Millar SE. WNT signals are required for the initiation of hair follicle development. Dev Cell 2002, 2:643-653.
    • (2002) Dev Cell , vol.2 , pp. 643-653
    • Andl, T.1    Reddy, S.T.2    Gaddapara, T.3    Millar, S.E.4
  • 104
    • 0035907041 scopus 로고    scopus 로고
    • β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W. β-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 2001, 105:533-545.
    • (2001) Cell , vol.105 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 105
    • 0032567078 scopus 로고    scopus 로고
    • Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin
    • Gat U, DasGupta R, Degenstein L, Fuchs ED. Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin. Cell 1998, 95:605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.D.4
  • 106
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice
    • van Genderen C et al. Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 1994, 8:2691-2703.
    • (1994) Genes Dev , vol.8 , pp. 2691-2703
    • van Genderen, C.1
  • 107
    • 0036852151 scopus 로고    scopus 로고
    • Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
    • Balciunaite G et al. Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice. Nat Immunol 2002, 3:1102-1108.
    • (2002) Nat Immunol , vol.3 , pp. 1102-1108
    • Balciunaite, G.1
  • 108
    • 33845609951 scopus 로고    scopus 로고
    • The Wnt signaling antagonist Kremen1 is required for development of thymic architecture
    • Osada M et al. The Wnt signaling antagonist Kremen1 is required for development of thymic architecture. Clin Dev Immunol 2006, 13:299-319.
    • (2006) Clin Dev Immunol , vol.13 , pp. 299-319
    • Osada, M.1
  • 110
    • 33749411672 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC) is required for normal development of skin and thymus
    • Kuraguchi M et al. Adenomatous polyposis coli (APC) is required for normal development of skin and thymus. PLoS Genet 2006, 2:e146.
    • (2006) PLoS Genet , vol.2 , pp. e146
    • Kuraguchi, M.1
  • 111
    • 84857444836 scopus 로고    scopus 로고
    • Eph/ephrin signaling in epidermal differentiation and disease
    • Lin S, Wang B, Getsios S. Eph/ephrin signaling in epidermal differentiation and disease. Semin Cell Dev Biol 2012, 23:92-101.
    • (2012) Semin Cell Dev Biol , vol.23 , pp. 92-101
    • Lin, S.1    Wang, B.2    Getsios, S.3
  • 112
    • 84874923547 scopus 로고    scopus 로고
    • Ephrin-B-dependent thymic epithelial cell-thymocyte interactions are necessary for correct T cell differentiation and thymus histology organization: relevance for thymic cortex development
    • Cejalvo T et al. Ephrin-B-dependent thymic epithelial cell-thymocyte interactions are necessary for correct T cell differentiation and thymus histology organization: relevance for thymic cortex development. J Immunol 2013, 190:2670-2681.
    • (2013) J Immunol , vol.190 , pp. 2670-2681
    • Cejalvo, T.1
  • 113
    • 33745834379 scopus 로고    scopus 로고
    • Thymic alterations in EphA4-deficient mice
    • Munoz JJ et al. Thymic alterations in EphA4-deficient mice. J Immunol 2006, 177:804-813.
    • (2006) J Immunol , vol.177 , pp. 804-813
    • Munoz, J.J.1
  • 114
    • 4644360116 scopus 로고    scopus 로고
    • Compartmentalized Eph receptor and ephrin expression in the thymus
    • Vergara-Silva A, Schaefer KL, Berg LJ. Compartmentalized Eph receptor and ephrin expression in the thymus. Mech Dev 2002, 119(Suppl 1):S225-229.
    • (2002) Mech Dev , vol.119 , pp. S225-S229
    • Vergara-Silva, A.1    Schaefer, K.L.2    Berg, L.J.3
  • 115
    • 78649685203 scopus 로고    scopus 로고
    • Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1
    • Lin S, Gordon K, Kaplan N, Getsios S. Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1. Mol Biol Cell 2010, 21:3902-3914.
    • (2010) Mol Biol Cell , vol.21 , pp. 3902-3914
    • Lin, S.1    Gordon, K.2    Kaplan, N.3    Getsios, S.4
  • 116
    • 77954823673 scopus 로고    scopus 로고
    • Ephrins negatively regulate cell proliferation in the epidermis and hair follicle
    • Genander M, Holmberg J, Frisen J. Ephrins negatively regulate cell proliferation in the epidermis and hair follicle. Stem Cells 2010, 28:1196-1205.
    • (2010) Stem Cells , vol.28 , pp. 1196-1205
    • Genander, M.1    Holmberg, J.2    Frisen, J.3
  • 117
    • 33746929036 scopus 로고    scopus 로고
    • Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin
    • Guo H et al. Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin. Cancer Res 2006, 66:7050-7058.
    • (2006) Cancer Res , vol.66 , pp. 7050-7058
    • Guo, H.1
  • 118
    • 35348927451 scopus 로고    scopus 로고
    • Desmosomes: new perspectives on a classic
    • Green KJ, Simpson CL. Desmosomes: new perspectives on a classic. J Invest Dermatol 2007, 127:2499-2515.
    • (2007) J Invest Dermatol , vol.127 , pp. 2499-2515
    • Green, K.J.1    Simpson, C.L.2
  • 119
    • 0034868746 scopus 로고    scopus 로고
    • Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival
    • Sano S et al. Stat3 in thymic epithelial cells is essential for postnatal maintenance of thymic architecture and thymocyte survival. Immunity 2001, 15:261-273.
    • (2001) Immunity , vol.15 , pp. 261-273
    • Sano, S.1
  • 120
    • 49249138982 scopus 로고    scopus 로고
    • Alterations in the thymocyte phenotype of EphB-deficient mice largely affect the double negative cell compartment
    • Alfaro D et al. Alterations in the thymocyte phenotype of EphB-deficient mice largely affect the double negative cell compartment. Immunology 2008, 125:131-143.
    • (2008) Immunology , vol.125 , pp. 131-143
    • Alfaro, D.1
  • 121
    • 2142764419 scopus 로고    scopus 로고
    • Eph-ephrin promiscuity is now crystal clear
    • Pasquale EB. Eph-ephrin promiscuity is now crystal clear. Nat Neurosci 2004, 7:417-418.
    • (2004) Nat Neurosci , vol.7 , pp. 417-418
    • Pasquale, E.B.1
  • 122
    • 0345689338 scopus 로고    scopus 로고
    • BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis
    • Tsai PT, Lee RA, Wu H. BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis. Blood 2003, 102:3947-3953.
    • (2003) Blood , vol.102 , pp. 3947-3953
    • Tsai, P.T.1    Lee, R.A.2    Wu, H.3
  • 123
    • 0037111391 scopus 로고    scopus 로고
    • Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation
    • Hager-Theodorides AL et al. Bone morphogenetic protein 2/4 signaling regulates early thymocyte differentiation. J Immunol 2002, 169:5496-5504.
    • (2002) J Immunol , vol.169 , pp. 5496-5504
    • Hager-Theodorides, A.L.1
  • 124
    • 0028790603 scopus 로고
    • Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction
    • Hawley SH et al. Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev 1995, 9:2923-2935.
    • (1995) Genes Dev , vol.9 , pp. 2923-2935
    • Hawley, S.H.1
  • 125
    • 0032933798 scopus 로고    scopus 로고
    • In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning
    • Nikaido M, Tada M, Takeda H, Kuroiwa A, Ueno N. In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning. Development 1999, 126:181-190.
    • (1999) Development , vol.126 , pp. 181-190
    • Nikaido, M.1    Tada, M.2    Takeda, H.3    Kuroiwa, A.4    Ueno, N.5
  • 126
    • 0033161898 scopus 로고    scopus 로고
    • Noggin is a mesenchymally derived stimulator of hair-follicle induction
    • Botchkarev VA et al. Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol 1999, 1:158-164.
    • (1999) Nat Cell Biol , vol.1 , pp. 158-164
    • Botchkarev, V.A.1
  • 127
    • 0037456847 scopus 로고    scopus 로고
    • Links between signal transduction, transcription and adhesion in epithelial bud development
    • Jamora C, DasGupta R, Kocieniewski P, Fuchs E. Links between signal transduction, transcription and adhesion in epithelial bud development. Nature 2003, 422:317-322.
    • (2003) Nature , vol.422 , pp. 317-322
    • Jamora, C.1    DasGupta, R.2    Kocieniewski, P.3    Fuchs, E.4
  • 128
    • 0034671830 scopus 로고    scopus 로고
    • Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle
    • Kulessa H, Turk G, Hogan BL. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle. EMBO J 2000, 19:6664-6674.
    • (2000) EMBO J , vol.19 , pp. 6664-6674
    • Kulessa, H.1    Turk, G.2    Hogan, B.L.3
  • 129
    • 26844543561 scopus 로고    scopus 로고
    • BMP signaling is required for normal thymus development
    • Bleul CC, Boehm T. BMP signaling is required for normal thymus development. J Immunol 2005, 175:5213-5221.
    • (2005) J Immunol , vol.175 , pp. 5213-5221
    • Bleul, C.C.1    Boehm, T.2
  • 131
    • 33751078603 scopus 로고    scopus 로고
    • Canonical notch signaling functions as a commitment switch in the epidermal lineage
    • Blanpain C, Lowry WE, Pasolli HA, Fuchs E. Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev 2006, 20:3022-3035.
    • (2006) Genes Dev , vol.20 , pp. 3022-3035
    • Blanpain, C.1    Lowry, W.E.2    Pasolli, H.A.3    Fuchs, E.4
  • 132
    • 41649088627 scopus 로고    scopus 로고
    • Multiple roles of Notch signaling in the regulation of epidermal development
    • Moriyama M et al. Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell 2008, 14:594-604.
    • (2008) Dev Cell , vol.14 , pp. 594-604
    • Moriyama, M.1
  • 133
    • 17844384528 scopus 로고    scopus 로고
    • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
    • Rangarajan A et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J 2001, 20:3427-3436.
    • (2001) EMBO J , vol.20 , pp. 3427-3436
    • Rangarajan, A.1
  • 134
    • 0035179878 scopus 로고    scopus 로고
    • Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling
    • Anderson G, Pongracz J, Parnell S, Jenkinson EJ. Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling. Eur J Immunol 2001, 31:3349-3354.
    • (2001) Eur J Immunol , vol.31 , pp. 3349-3354
    • Anderson, G.1    Pongracz, J.2    Parnell, S.3    Jenkinson, E.J.4
  • 135
    • 84892459800 scopus 로고    scopus 로고
    • Epithelial stem cells in adult skin
    • Tadeu AM, Horsley V. Epithelial stem cells in adult skin. Curr Top Dev Biol 2014, 107:109-131.
    • (2014) Curr Top Dev Biol , vol.107 , pp. 109-131
    • Tadeu, A.M.1    Horsley, V.2
  • 136
    • 67349171030 scopus 로고    scopus 로고
    • Phenotypical and morphological changes in the thymic microenvironment from ageing mice
    • Aw D, Taylor-Brown F, Cooper K, Palmer DB. Phenotypical and morphological changes in the thymic microenvironment from ageing mice. Biogerontology 2009, 10:311-322.
    • (2009) Biogerontology , vol.10 , pp. 311-322
    • Aw, D.1    Taylor-Brown, F.2    Cooper, K.3    Palmer, D.B.4
  • 137
    • 84856449868 scopus 로고    scopus 로고
    • The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin
    • Driskell I et al. The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. EMBO J 2012, 31:616-629.
    • (2012) EMBO J , vol.31 , pp. 616-629
    • Driskell, I.1
  • 138
    • 80052261506 scopus 로고    scopus 로고
    • Jarid2 regulates mouse epidermal stem cell activation and differentiation
    • Mejetta S et al. Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J 2011, 30:3635-3646.
    • (2011) EMBO J , vol.30 , pp. 3635-3646
    • Mejetta, S.1
  • 139
    • 84890350271 scopus 로고    scopus 로고
    • Distinct fibroblast lineages determine dermal architecture in skin development and repair
    • Driskell RR et al. Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature 2013, 504:277-281.
    • (2013) Nature , vol.504 , pp. 277-281
    • Driskell, R.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.