-
2
-
-
8444236025
-
The adenomatous polyposis coli protein: The Achilles heel of the gut epithelium
-
Nathke IS (2004) The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium. Annu Rev Cell Dev Biol 20: 337-366.
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 337-366
-
-
Nathke, I.S.1
-
3
-
-
0037340399
-
The multiple functions of tumour suppressors: It's all in APC
-
Fodde R (2003) The multiple functions of tumour suppressors: It's all in APC. Nat Cell Biol 5: 190-192.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 190-192
-
-
Fodde, R.1
-
4
-
-
0030592517
-
Lessons from hereditary colorectal cancer
-
Kinzler KW, Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170.
-
(1996)
Cell
, vol.87
, pp. 159-170
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
5
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, et al. (1991) Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66: 589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
Carlson, M.4
Gelbert, L.5
-
7
-
-
0031408413
-
Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis
-
Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, et al. (1997) Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis 18: 321-327.
-
(1997)
Carcinogenesis
, vol.18
, pp. 321-327
-
-
Smits, R.1
Kartheuser, A.2
Jagmohan-Changur, S.3
Leblanc, V.4
Breukel, C.5
-
8
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C, et al. (1995) Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci U S A 92: 4482-4486.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
Kobayashi, M.4
Itakura, C.5
-
9
-
-
0029143510
-
ApcMin: A mouse model for intestinal and mammary tumorigenesis
-
Moser AR, Luongo C, Gould KA, McNeley MK, Shoemaker AR, et al. (1995) ApcMin: A mouse model for intestinal and mammary tumorigenesis. Eur J Cancer 31A: 1061-1064.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1061-1064
-
-
Moser, A.R.1
Luongo, C.2
Gould, K.A.3
McNeley, M.K.4
Shoemaker, A.R.5
-
10
-
-
0028567875
-
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde R, Edelmann W, Yang K, van Leeuwen C, Carlson C, et al. (1994) A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci U S A 91: 8969-8973.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelmann, W.2
Yang, K.3
Van Leeuwen, C.4
Carlson, C.5
-
11
-
-
0037440378
-
Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo
-
Ishikawa TO, Tamai Y, Li Q, Oshima M, Taketo MM (2003) Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo. Dev Biol 253: 230-246.
-
(2003)
Dev Biol
, vol.253
, pp. 230-246
-
-
Ishikawa, T.O.1
Tamai, Y.2
Li, Q.3
Oshima, M.4
Taketo, M.M.5
-
12
-
-
0035308590
-
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
-
Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, et al. (2001) A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73: 56-65.
-
(2001)
Genomics
, vol.73
, pp. 56-65
-
-
Lee, E.C.1
Yu, D.2
Martinez De Velasco, J.3
Tessarollo, L.4
Swing, D.A.5
-
13
-
-
0037352031
-
A highly efficient recombineering-based method for generating conditional knockout mutations
-
Liu P, Jenkins NA, Copeland NG (2003) A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res 13: 476-484.
-
(2003)
Genome Res
, vol.13
, pp. 476-484
-
-
Liu, P.1
Jenkins, N.A.2
Copeland, N.G.3
-
14
-
-
10044221016
-
Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
-
Colnot S, Niwa-Kawakita M, Hamard G, Godard C, Le Plenier S, et al. (2004) Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers. Lab Invest 84: 1619-1630.
-
(2004)
Lab Invest
, vol.84
, pp. 1619-1630
-
-
Colnot, S.1
Niwa-Kawakita, M.2
Hamard, G.3
Godard, C.4
Le Plenier, S.5
-
15
-
-
0029091809
-
WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras
-
Ioffe E, Liu Y, Bhaumik M, Poirier F, Factor SM, et al. (1995) WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras. Proc Natl Acad Sci U S A 92: 7357-7361.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7357-7361
-
-
Ioffe, E.1
Liu, Y.2
Bhaumik, M.3
Poirier, F.4
Factor, S.M.5
-
16
-
-
0035734285
-
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
-
Jonkers J, Meuwissen R, van der Gulden H, Peterse H, van der Valk M, et al. (2001) Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29: 418-425.
-
(2001)
Nat Genet
, vol.29
, pp. 418-425
-
-
Jonkers, J.1
Meuwissen, R.2
Van Der Gulden, H.3
Peterse, H.4
Van Der Valk, M.5
-
17
-
-
2342471358
-
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein
-
Hafner M, Wenk J, Nenci A, Pasparakis M, Scharffetter-Kochanek K, et al. (2004) Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein. Genesis 38: 176-181.
-
(2004)
Genesis
, vol.38
, pp. 176-181
-
-
Hafner, M.1
Wenk, J.2
Nenci, A.3
Pasparakis, M.4
Scharffetter-Kochanek, K.5
-
18
-
-
0018866880
-
Changes in keratin gene expression during terminal differentiation of the keratinocyte
-
Fuchs E, Green H (1980) Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell 19: 1033-1042.
-
(1980)
Cell
, vol.19
, pp. 1033-1042
-
-
Fuchs, E.1
Green, H.2
-
19
-
-
0028025616
-
Programming gene expression in developing epidermis
-
Byrne C, Tainsky M, Fuchs E (1994) Programming gene expression in developing epidermis. Development 120: 2369-2383.
-
(1994)
Development
, vol.120
, pp. 2369-2383
-
-
Byrne, C.1
Tainsky, M.2
Fuchs, E.3
-
20
-
-
0030474645
-
The cytoskeleton and disease: Genetic disorders of intermediate filaments
-
Fuchs E (1996) The cytoskeleton and disease: Genetic disorders of intermediate filaments. Annu Rev Genet 30: 197-231.
-
(1996)
Annu Rev Genet
, vol.30
, pp. 197-231
-
-
Fuchs, E.1
-
21
-
-
0031865846
-
Patterned acquisition of skin barrier function during development
-
Hardman MJ, Sisi P, Banbury DN, Byrne C (1998) Patterned acquisition of skin barrier function during development. Development 125: 1541-1552.
-
(1998)
Development
, vol.125
, pp. 1541-1552
-
-
Hardman, M.J.1
Sisi, P.2
Banbury, D.N.3
Byrne, C.4
-
22
-
-
0141706431
-
Stem cells of the skin epithelium
-
Alonso L, Fuchs E (2003) Stem cells of the skin epithelium. Proc Natl Acad Sci U S A 100 (Suppl 1): 11830-11835.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.1 SUPPL.
, pp. 11830-11835
-
-
Alonso, L.1
Fuchs, E.2
-
23
-
-
0038274074
-
Stem cells in the skin: Waste not, Wnt not
-
Alonso L, Fuchs E (2003) Stem cells in the skin: Waste not, Wnt not. Genes Dev 17: 1189-1200.
-
(2003)
Genes Dev
, vol.17
, pp. 1189-1200
-
-
Alonso, L.1
Fuchs, E.2
-
24
-
-
0036178229
-
Molecular mechanisms regulating hair follicle development
-
Millar SE (2002) Molecular mechanisms regulating hair follicle development. J Invest Dermatol 118: 216-225.
-
(2002)
J Invest Dermatol
, vol.118
, pp. 216-225
-
-
Millar, S.E.1
-
25
-
-
0032567078
-
De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
-
Gat U, DasGupta R, Degenstein L, Fuchs E (1998) De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95: 605-614.
-
(1998)
Cell
, vol.95
, pp. 605-614
-
-
Gat, U.1
DasGupta, R.2
Degenstein, L.3
Fuchs, E.4
-
27
-
-
0028935955
-
Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate
-
Zhou P, Byrne C, Jacobs J, Fuchs E (1995) Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9: 700-713.
-
(1995)
Genes Dev
, vol.9
, pp. 700-713
-
-
Zhou, P.1
Byrne, C.2
Jacobs, J.3
Fuchs, E.4
-
28
-
-
0035907041
-
Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
-
Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W (2001) beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105: 533-545.
-
(2001)
Cell
, vol.105
, pp. 533-545
-
-
Huelsken, J.1
Vogel, R.2
Erdmann, B.3
Cotsarelis, G.4
Birchmeier, W.5
-
29
-
-
0036113510
-
WNT signals are required for the initiation of hair follicle development
-
Andl T, Reddy ST, Gaddapara T, Millar SE (2002) WNT signals are required for the initiation of hair follicle development. Dev Cell 2: 643-653.
-
(2002)
Dev Cell
, vol.2
, pp. 643-653
-
-
Andl, T.1
Reddy, S.T.2
Gaddapara, T.3
Millar, S.E.4
-
30
-
-
0027945654
-
Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-deficient mice
-
van Genderen C, Okamura RM, Farinas I, Quo RG, Parslow TG, et al. (1994) Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 8: 2691-2703.
-
(1994)
Genes Dev
, vol.8
, pp. 2691-2703
-
-
Van Genderen, C.1
Okamura, R.M.2
Farinas, I.3
Quo, R.G.4
Parslow, T.G.5
-
31
-
-
0031031056
-
Transgenic studies with a keratin promoter-driven growth hormone transgene: Prospects for gene therapy
-
Wang X, Zinkel S, Polonsky K, Fuchs E (1997) Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. Proc Natl Acad Sci U S A 94: 219-226.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 219-226
-
-
Wang, X.1
Zinkel, S.2
Polonsky, K.3
Fuchs, E.4
-
32
-
-
0032578456
-
Interdependence of cortical thymic epithelial cell differentiation and Tlineage commitment
-
Klug DB, Carter C, Crouch E, Roop D, Conti CJ, et al. (1998) Interdependence of cortical thymic epithelial cell differentiation and Tlineage commitment. Proc Natl Acad Sci U S A 95: 11822-11827.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 11822-11827
-
-
Klug, D.B.1
Carter, C.2
Crouch, E.3
Roop, D.4
Conti, C.J.5
-
33
-
-
23944472219
-
Loss of adenomatous polyposis coli gene function disrupts thymic development
-
Gounari F, Chang R, Cowan J, Guo Z, Dose M, et al. (2005) Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat Immunol 6: 800-809.
-
(2005)
Nat Immunol
, vol.6
, pp. 800-809
-
-
Gounari, F.1
Chang, R.2
Cowan, J.3
Guo, Z.4
Dose, M.5
-
34
-
-
0034041160
-
High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP
-
Rodriguez CI, Buchholz F, Galloway J, Sequerra R, Kasper J, et al. (2000) High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat Genet 25: 139-140.
-
(2000)
Nat Genet
, vol.25
, pp. 139-140
-
-
Rodriguez, C.I.1
Buchholz, F.2
Galloway, J.3
Sequerra, R.4
Kasper, J.5
-
35
-
-
0030008349
-
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
-
Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, et al. (1996) Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci U S A 93: 5860-5865.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5860-5865
-
-
Lakso, M.1
Pichel, J.G.2
Gorman, J.R.3
Sauer, B.4
Okamoto, Y.5
-
36
-
-
0036336486
-
Permeability barrier dysfunction in transgenic mice overexpressing claudin 6
-
Turksen K, Troy TC (2002) Permeability barrier dysfunction in transgenic mice overexpressing claudin 6. Development 129: 1775-1784.
-
(2002)
Development
, vol.129
, pp. 1775-1784
-
-
Turksen, K.1
Troy, T.C.2
-
37
-
-
15544385745
-
Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth
-
Wang XP, Aberg T, James MJ, Levanon D, Groner Y, et al. (2005) Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. J Dent Res 84: 138-143.
-
(2005)
J Dent Res
, vol.84
, pp. 138-143
-
-
Wang, X.P.1
Aberg, T.2
James, M.J.3
Levanon, D.4
Groner, Y.5
-
38
-
-
0036333966
-
Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar
-
Laurikkala J, Pispa J, Jung HS, Nieminen P, Mikkola M, et al. (2002) Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development 129: 2541-2553.
-
(2002)
Development
, vol.129
, pp. 2541-2553
-
-
Laurikkala, J.1
Pispa, J.2
Jung, H.S.3
Nieminen, P.4
Mikkola, M.5
-
39
-
-
0033555669
-
Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling
-
Murtaugh LC, Chyung JH, Lassar AB (1999) Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling. Genes Dev 13: 225-237.
-
(1999)
Genes Dev
, vol.13
, pp. 225-237
-
-
Murtaugh, L.C.1
Chyung, J.H.2
Lassar, A.B.3
-
40
-
-
0027760995
-
Sonic hedgehog mediates the polarizing activity of the ZPA
-
Riddle RD, Johnson RL, Laufer E, Tabin C (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75: 1401-1416.
-
(1993)
Cell
, vol.75
, pp. 1401-1416
-
-
Riddle, R.D.1
Johnson, R.L.2
Laufer, E.3
Tabin, C.4
|