메뉴 건너뛰기




Volumn 2, Issue 9, 2006, Pages 1362-1374

Adenomatous polyposis coli (APC) is required for normal development of skin and thymus

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; CRE RECOMBINASE; CYTOKERATIN 14; WNT PROTEIN; BETA CATENIN; KERATIN; MESSENGER RNA; SHH PROTEIN, MOUSE; SONIC HEDGEHOG PROTEIN;

EID: 33749411672     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020146     Document Type: Article
Times cited : (157)

References (40)
  • 2
    • 8444236025 scopus 로고    scopus 로고
    • The adenomatous polyposis coli protein: The Achilles heel of the gut epithelium
    • Nathke IS (2004) The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium. Annu Rev Cell Dev Biol 20: 337-366.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 337-366
    • Nathke, I.S.1
  • 3
    • 0037340399 scopus 로고    scopus 로고
    • The multiple functions of tumour suppressors: It's all in APC
    • Fodde R (2003) The multiple functions of tumour suppressors: It's all in APC. Nat Cell Biol 5: 190-192.
    • (2003) Nat Cell Biol , vol.5 , pp. 190-192
    • Fodde, R.1
  • 4
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B (1996) Lessons from hereditary colorectal cancer. Cell 87: 159-170.
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 5
    • 0025938038 scopus 로고
    • Identification and characterization of the familial adenomatous polyposis coli gene
    • Groden J, Thliveris A, Samowitz W, Carlson M, Gelbert L, et al. (1991) Identification and characterization of the familial adenomatous polyposis coli gene. Cell 66: 589-600.
    • (1991) Cell , vol.66 , pp. 589-600
    • Groden, J.1    Thliveris, A.2    Samowitz, W.3    Carlson, M.4    Gelbert, L.5
  • 7
    • 0031408413 scopus 로고    scopus 로고
    • Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis
    • Smits R, Kartheuser A, Jagmohan-Changur S, Leblanc V, Breukel C, et al. (1997) Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis. Carcinogenesis 18: 321-327.
    • (1997) Carcinogenesis , vol.18 , pp. 321-327
    • Smits, R.1    Kartheuser, A.2    Jagmohan-Changur, S.3    Leblanc, V.4    Breukel, C.5
  • 8
    • 0029047954 scopus 로고
    • Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
    • Oshima M, Oshima H, Kitagawa K, Kobayashi M, Itakura C, et al. (1995) Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Natl Acad Sci U S A 92: 4482-4486.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4482-4486
    • Oshima, M.1    Oshima, H.2    Kitagawa, K.3    Kobayashi, M.4    Itakura, C.5
  • 10
    • 0028567875 scopus 로고
    • A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
    • Fodde R, Edelmann W, Yang K, van Leeuwen C, Carlson C, et al. (1994) A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci U S A 91: 8969-8973.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 8969-8973
    • Fodde, R.1    Edelmann, W.2    Yang, K.3    Van Leeuwen, C.4    Carlson, C.5
  • 11
    • 0037440378 scopus 로고    scopus 로고
    • Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo
    • Ishikawa TO, Tamai Y, Li Q, Oshima M, Taketo MM (2003) Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo. Dev Biol 253: 230-246.
    • (2003) Dev Biol , vol.253 , pp. 230-246
    • Ishikawa, T.O.1    Tamai, Y.2    Li, Q.3    Oshima, M.4    Taketo, M.M.5
  • 12
    • 0035308590 scopus 로고    scopus 로고
    • A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA
    • Lee EC, Yu D, Martinez de Velasco J, Tessarollo L, Swing DA, et al. (2001) A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics 73: 56-65.
    • (2001) Genomics , vol.73 , pp. 56-65
    • Lee, E.C.1    Yu, D.2    Martinez De Velasco, J.3    Tessarollo, L.4    Swing, D.A.5
  • 13
    • 0037352031 scopus 로고    scopus 로고
    • A highly efficient recombineering-based method for generating conditional knockout mutations
    • Liu P, Jenkins NA, Copeland NG (2003) A highly efficient recombineering-based method for generating conditional knockout mutations. Genome Res 13: 476-484.
    • (2003) Genome Res , vol.13 , pp. 476-484
    • Liu, P.1    Jenkins, N.A.2    Copeland, N.G.3
  • 14
    • 10044221016 scopus 로고    scopus 로고
    • Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
    • Colnot S, Niwa-Kawakita M, Hamard G, Godard C, Le Plenier S, et al. (2004) Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers. Lab Invest 84: 1619-1630.
    • (2004) Lab Invest , vol.84 , pp. 1619-1630
    • Colnot, S.1    Niwa-Kawakita, M.2    Hamard, G.3    Godard, C.4    Le Plenier, S.5
  • 15
    • 0029091809 scopus 로고
    • WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras
    • Ioffe E, Liu Y, Bhaumik M, Poirier F, Factor SM, et al. (1995) WW6: An embryonic stem cell line with an inert genetic marker that can be traced in chimeras. Proc Natl Acad Sci U S A 92: 7357-7361.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7357-7361
    • Ioffe, E.1    Liu, Y.2    Bhaumik, M.3    Poirier, F.4    Factor, S.M.5
  • 16
    • 0035734285 scopus 로고    scopus 로고
    • Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
    • Jonkers J, Meuwissen R, van der Gulden H, Peterse H, van der Valk M, et al. (2001) Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet 29: 418-425.
    • (2001) Nat Genet , vol.29 , pp. 418-425
    • Jonkers, J.1    Meuwissen, R.2    Van Der Gulden, H.3    Peterse, H.4    Van Der Valk, M.5
  • 17
    • 2342471358 scopus 로고    scopus 로고
    • Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein
    • Hafner M, Wenk J, Nenci A, Pasparakis M, Scharffetter-Kochanek K, et al. (2004) Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein. Genesis 38: 176-181.
    • (2004) Genesis , vol.38 , pp. 176-181
    • Hafner, M.1    Wenk, J.2    Nenci, A.3    Pasparakis, M.4    Scharffetter-Kochanek, K.5
  • 18
    • 0018866880 scopus 로고
    • Changes in keratin gene expression during terminal differentiation of the keratinocyte
    • Fuchs E, Green H (1980) Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell 19: 1033-1042.
    • (1980) Cell , vol.19 , pp. 1033-1042
    • Fuchs, E.1    Green, H.2
  • 19
    • 0028025616 scopus 로고
    • Programming gene expression in developing epidermis
    • Byrne C, Tainsky M, Fuchs E (1994) Programming gene expression in developing epidermis. Development 120: 2369-2383.
    • (1994) Development , vol.120 , pp. 2369-2383
    • Byrne, C.1    Tainsky, M.2    Fuchs, E.3
  • 20
    • 0030474645 scopus 로고    scopus 로고
    • The cytoskeleton and disease: Genetic disorders of intermediate filaments
    • Fuchs E (1996) The cytoskeleton and disease: Genetic disorders of intermediate filaments. Annu Rev Genet 30: 197-231.
    • (1996) Annu Rev Genet , vol.30 , pp. 197-231
    • Fuchs, E.1
  • 21
    • 0031865846 scopus 로고    scopus 로고
    • Patterned acquisition of skin barrier function during development
    • Hardman MJ, Sisi P, Banbury DN, Byrne C (1998) Patterned acquisition of skin barrier function during development. Development 125: 1541-1552.
    • (1998) Development , vol.125 , pp. 1541-1552
    • Hardman, M.J.1    Sisi, P.2    Banbury, D.N.3    Byrne, C.4
  • 22
    • 0141706431 scopus 로고    scopus 로고
    • Stem cells of the skin epithelium
    • Alonso L, Fuchs E (2003) Stem cells of the skin epithelium. Proc Natl Acad Sci U S A 100 (Suppl 1): 11830-11835.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.1 SUPPL. , pp. 11830-11835
    • Alonso, L.1    Fuchs, E.2
  • 23
    • 0038274074 scopus 로고    scopus 로고
    • Stem cells in the skin: Waste not, Wnt not
    • Alonso L, Fuchs E (2003) Stem cells in the skin: Waste not, Wnt not. Genes Dev 17: 1189-1200.
    • (2003) Genes Dev , vol.17 , pp. 1189-1200
    • Alonso, L.1    Fuchs, E.2
  • 24
    • 0036178229 scopus 로고    scopus 로고
    • Molecular mechanisms regulating hair follicle development
    • Millar SE (2002) Molecular mechanisms regulating hair follicle development. J Invest Dermatol 118: 216-225.
    • (2002) J Invest Dermatol , vol.118 , pp. 216-225
    • Millar, S.E.1
  • 25
    • 0032567078 scopus 로고    scopus 로고
    • De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin
    • Gat U, DasGupta R, Degenstein L, Fuchs E (1998) De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95: 605-614.
    • (1998) Cell , vol.95 , pp. 605-614
    • Gat, U.1    DasGupta, R.2    Degenstein, L.3    Fuchs, E.4
  • 27
    • 0028935955 scopus 로고
    • Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate
    • Zhou P, Byrne C, Jacobs J, Fuchs E (1995) Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9: 700-713.
    • (1995) Genes Dev , vol.9 , pp. 700-713
    • Zhou, P.1    Byrne, C.2    Jacobs, J.3    Fuchs, E.4
  • 28
    • 0035907041 scopus 로고    scopus 로고
    • Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin
    • Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W (2001) beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin. Cell 105: 533-545.
    • (2001) Cell , vol.105 , pp. 533-545
    • Huelsken, J.1    Vogel, R.2    Erdmann, B.3    Cotsarelis, G.4    Birchmeier, W.5
  • 29
    • 0036113510 scopus 로고    scopus 로고
    • WNT signals are required for the initiation of hair follicle development
    • Andl T, Reddy ST, Gaddapara T, Millar SE (2002) WNT signals are required for the initiation of hair follicle development. Dev Cell 2: 643-653.
    • (2002) Dev Cell , vol.2 , pp. 643-653
    • Andl, T.1    Reddy, S.T.2    Gaddapara, T.3    Millar, S.E.4
  • 30
    • 0027945654 scopus 로고
    • Development of several organs that require inductive epithelial- mesenchymal interactions is impaired in LEF-1-deficient mice
    • van Genderen C, Okamura RM, Farinas I, Quo RG, Parslow TG, et al. (1994) Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 8: 2691-2703.
    • (1994) Genes Dev , vol.8 , pp. 2691-2703
    • Van Genderen, C.1    Okamura, R.M.2    Farinas, I.3    Quo, R.G.4    Parslow, T.G.5
  • 31
    • 0031031056 scopus 로고    scopus 로고
    • Transgenic studies with a keratin promoter-driven growth hormone transgene: Prospects for gene therapy
    • Wang X, Zinkel S, Polonsky K, Fuchs E (1997) Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. Proc Natl Acad Sci U S A 94: 219-226.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 219-226
    • Wang, X.1    Zinkel, S.2    Polonsky, K.3    Fuchs, E.4
  • 32
    • 0032578456 scopus 로고    scopus 로고
    • Interdependence of cortical thymic epithelial cell differentiation and Tlineage commitment
    • Klug DB, Carter C, Crouch E, Roop D, Conti CJ, et al. (1998) Interdependence of cortical thymic epithelial cell differentiation and Tlineage commitment. Proc Natl Acad Sci U S A 95: 11822-11827.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11822-11827
    • Klug, D.B.1    Carter, C.2    Crouch, E.3    Roop, D.4    Conti, C.J.5
  • 33
    • 23944472219 scopus 로고    scopus 로고
    • Loss of adenomatous polyposis coli gene function disrupts thymic development
    • Gounari F, Chang R, Cowan J, Guo Z, Dose M, et al. (2005) Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat Immunol 6: 800-809.
    • (2005) Nat Immunol , vol.6 , pp. 800-809
    • Gounari, F.1    Chang, R.2    Cowan, J.3    Guo, Z.4    Dose, M.5
  • 34
    • 0034041160 scopus 로고    scopus 로고
    • High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP
    • Rodriguez CI, Buchholz F, Galloway J, Sequerra R, Kasper J, et al. (2000) High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat Genet 25: 139-140.
    • (2000) Nat Genet , vol.25 , pp. 139-140
    • Rodriguez, C.I.1    Buchholz, F.2    Galloway, J.3    Sequerra, R.4    Kasper, J.5
  • 35
    • 0030008349 scopus 로고    scopus 로고
    • Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
    • Lakso M, Pichel JG, Gorman JR, Sauer B, Okamoto Y, et al. (1996) Efficient in vivo manipulation of mouse genomic sequences at the zygote stage. Proc Natl Acad Sci U S A 93: 5860-5865.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5860-5865
    • Lakso, M.1    Pichel, J.G.2    Gorman, J.R.3    Sauer, B.4    Okamoto, Y.5
  • 36
    • 0036336486 scopus 로고    scopus 로고
    • Permeability barrier dysfunction in transgenic mice overexpressing claudin 6
    • Turksen K, Troy TC (2002) Permeability barrier dysfunction in transgenic mice overexpressing claudin 6. Development 129: 1775-1784.
    • (2002) Development , vol.129 , pp. 1775-1784
    • Turksen, K.1    Troy, T.C.2
  • 37
    • 15544385745 scopus 로고    scopus 로고
    • Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth
    • Wang XP, Aberg T, James MJ, Levanon D, Groner Y, et al. (2005) Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth. J Dent Res 84: 138-143.
    • (2005) J Dent Res , vol.84 , pp. 138-143
    • Wang, X.P.1    Aberg, T.2    James, M.J.3    Levanon, D.4    Groner, Y.5
  • 38
    • 0036333966 scopus 로고    scopus 로고
    • Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar
    • Laurikkala J, Pispa J, Jung HS, Nieminen P, Mikkola M, et al. (2002) Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development 129: 2541-2553.
    • (2002) Development , vol.129 , pp. 2541-2553
    • Laurikkala, J.1    Pispa, J.2    Jung, H.S.3    Nieminen, P.4    Mikkola, M.5
  • 39
    • 0033555669 scopus 로고    scopus 로고
    • Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling
    • Murtaugh LC, Chyung JH, Lassar AB (1999) Sonic hedgehog promotes somitic chondrogenesis by altering the cellular response to BMP signaling. Genes Dev 13: 225-237.
    • (1999) Genes Dev , vol.13 , pp. 225-237
    • Murtaugh, L.C.1    Chyung, J.H.2    Lassar, A.B.3
  • 40
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle RD, Johnson RL, Laufer E, Tabin C (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75: 1401-1416.
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.