메뉴 건너뛰기




Volumn 276, Issue 5, 2014, Pages 498-511

Fish oil supplementation induces expression of genes related to cell cycle, endoplasmic reticulum stress and apoptosis in peripheral blood mononuclear cells: A transcriptomic approach

Author keywords

Fish oil; Intervention; N 3 fatty acid; Peripheral blood mononuclear cells; Transcriptome

Indexed keywords

DOCOSAHEXAENOIC ACID; FISH OIL; G PROTEIN COUPLED RECEPTOR 120; ICOSAPENTAENOIC ACID; OMEGA 3 FATTY ACID; PROTEIN P53; SUNFLOWER OIL; TRANSCRIPTION FACTOR E2F; TRANSCRIPTOME;

EID: 84911437414     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/joim.12217     Document Type: Article
Times cited : (32)

References (54)
  • 1
    • 0037051975 scopus 로고    scopus 로고
    • Fish and omega-3 fatty acid intake and risk of coronary heart disease in women
    • Hu FB, Bronner L, Willett WC et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA 2002; 287: 1815-21.
    • (2002) JAMA , vol.287 , pp. 1815-1821
    • Hu, F.B.1    Bronner, L.2    Willett, W.C.3
  • 2
    • 2942548948 scopus 로고    scopus 로고
    • Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies
    • He K, Song Y, Daviglus ML et al. Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studies. Circulation 2004; 109: 2705-11.
    • (2004) Circulation , vol.109 , pp. 2705-2711
    • He, K.1    Song, Y.2    Daviglus, M.L.3
  • 3
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • GISSI-Prevenzione Investigators.
    • GISSI-Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 1999; 354: 447-55.
    • (1999) Lancet , vol.354 , pp. 447-455
  • 4
    • 84866070612 scopus 로고    scopus 로고
    • Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis
    • Rizos EC, Ntzani EE, Bika E, Kostapanos MS, Elisaf MS. Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis. JAMA 2012; 308: 1024-33.
    • (2012) JAMA , vol.308 , pp. 1024-1033
    • Rizos, E.C.1    Ntzani, E.E.2    Bika, E.3    Kostapanos, M.S.4    Elisaf, M.S.5
  • 5
    • 38749112555 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction
    • Packard RR, Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem 2008; 54: 24-38.
    • (2008) Clin Chem , vol.54 , pp. 24-38
    • Packard, R.R.1    Libby, P.2
  • 8
    • 33746830525 scopus 로고    scopus 로고
    • n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases
    • Calder PC. n-3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. Am J Clin Nutr 2006; 83: 1505S-19S.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1505S-1519S
    • Calder, P.C.1
  • 9
    • 3042786322 scopus 로고    scopus 로고
    • Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women
    • Lopez-Garcia E, Schulze MB, Manson JE et al. Consumption of (n-3) fatty acids is related to plasma biomarkers of inflammation and endothelial activation in women. J Nutr 2004; 134: 1806-11.
    • (2004) J Nutr , vol.134 , pp. 1806-1811
    • Lopez-Garcia, E.1    Schulze, M.B.2    Manson, J.E.3
  • 10
    • 0035889484 scopus 로고    scopus 로고
    • C-reactive protein, dietary n-3 fatty acids, and the extent of coronary artery disease
    • Madsen T, Skou HA, Hansen VE et al. C-reactive protein, dietary n-3 fatty acids, and the extent of coronary artery disease. Am J Cardiol 2001; 88: 1139-42.
    • (2001) Am J Cardiol , vol.88 , pp. 1139-1142
    • Madsen, T.1    Skou, H.A.2    Hansen, V.E.3
  • 11
    • 79955930583 scopus 로고    scopus 로고
    • Effect of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects and subjects with cardiovascular risk factors
    • Myhrstad MC, Retterstol K, Telle-Hansen VH et al. Effect of marine n-3 fatty acids on circulating inflammatory markers in healthy subjects and subjects with cardiovascular risk factors. Inflamm Res 2011; 60: 309-19.
    • (2011) Inflamm Res , vol.60 , pp. 309-319
    • Myhrstad, M.C.1    Retterstol, K.2    Telle-Hansen, V.H.3
  • 12
    • 0006132932 scopus 로고    scopus 로고
    • Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma
    • Kliewer SA, Sundseth SS, Jones SA et al. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma. Proc Natl Acad Sci U S A 1997; 94: 4318-23.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4318-4323
    • Kliewer, S.A.1    Sundseth, S.S.2    Jones, S.A.3
  • 13
    • 50649097541 scopus 로고    scopus 로고
    • Fat and beyond: the diverse biology of PPARgamma
    • Tontonoz P, Spiegelman BM. Fat and beyond: the diverse biology of PPARgamma. Annu Rev Biochem 2008; 77: 289-312.
    • (2008) Annu Rev Biochem , vol.77 , pp. 289-312
    • Tontonoz, P.1    Spiegelman, B.M.2
  • 14
    • 8444233254 scopus 로고    scopus 로고
    • Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation
    • Castrillo A, Tontonoz P. Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation. Annu Rev Cell Dev Biol 2004; 20: 455-80.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 455-480
    • Castrillo, A.1    Tontonoz, P.2
  • 15
    • 0038143617 scopus 로고    scopus 로고
    • Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids
    • Lee JY, Plakidas A, Lee WH et al. Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res 2003; 44: 479-86.
    • (2003) J Lipid Res , vol.44 , pp. 479-486
    • Lee, J.Y.1    Plakidas, A.2    Lee, W.H.3
  • 16
    • 77956165390 scopus 로고    scopus 로고
    • GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
    • Oh DY, Talukdar S, Bae EJ et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell 2010; 142: 687-98.
    • (2010) Cell , vol.142 , pp. 687-698
    • Oh, D.Y.1    Talukdar, S.2    Bae, E.J.3
  • 17
    • 33846876581 scopus 로고    scopus 로고
    • Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects
    • Ma J, Dempsey AA, Stamatiou D, Marshall KW, Liew CC. Identifying leukocyte gene expression patterns associated with plasma lipid levels in human subjects. Atherosclerosis 2007; 191: 63-72.
    • (2007) Atherosclerosis , vol.191 , pp. 63-72
    • Ma, J.1    Dempsey, A.A.2    Stamatiou, D.3    Marshall, K.W.4    Liew, C.C.5
  • 18
    • 84863538443 scopus 로고    scopus 로고
    • Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: what do we know so far?
    • de Mello VD, Kolehmanien M, Schwab U, Pulkkinen L, Uusitupa M. Gene expression of peripheral blood mononuclear cells as a tool in dietary intervention studies: what do we know so far? Mol Nutr Food Res 2012; 56: 1160-72.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 1160-1172
    • de Mello, V.D.1    Kolehmanien, M.2    Schwab, U.3    Pulkkinen, L.4    Uusitupa, M.5
  • 19
    • 36248967735 scopus 로고    scopus 로고
    • Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid beta-oxidation: functional role of peroxisome proliferator activated receptor alpha in human peripheral blood mononuclear cells
    • Bouwens M, Afman LA, Muller M. Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid beta-oxidation: functional role of peroxisome proliferator activated receptor alpha in human peripheral blood mononuclear cells. Am J Clin Nutr 2007; 86: 1515-23.
    • (2007) Am J Clin Nutr , vol.86 , pp. 1515-1523
    • Bouwens, M.1    Afman, L.A.2    Muller, M.3
  • 20
    • 77950493668 scopus 로고    scopus 로고
    • An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach
    • Bakker GC, van Erk MJ, Pellis L et al. An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach. Am J Clin Nutr 2010; 91: 1044-59.
    • (2010) Am J Clin Nutr , vol.91 , pp. 1044-1059
    • Bakker, G.C.1    van Erk, M.J.2    Pellis, L.3
  • 21
    • 79551508239 scopus 로고    scopus 로고
    • Validation of the use of peripheral blood mononuclear cells as surrogate model for skeletal muscle tissue in nutrigenomic studies
    • Rudkowska I, Raymond C, Ponton A et al. Validation of the use of peripheral blood mononuclear cells as surrogate model for skeletal muscle tissue in nutrigenomic studies. OMICS 2011; 15: 1-7.
    • (2011) OMICS , vol.15 , pp. 1-7
    • Rudkowska, I.1    Raymond, C.2    Ponton, A.3
  • 22
    • 84863839313 scopus 로고    scopus 로고
    • Oxidised fish oil does not influence established markers of oxidative stress in healthy human subjects: a randomised controlled trial
    • Ottestad I, Vogt G, Retterstol K et al. Oxidised fish oil does not influence established markers of oxidative stress in healthy human subjects: a randomised controlled trial. Br J Nutr 2011; 108: 315-26.
    • (2011) Br J Nutr , vol.108 , pp. 315-326
    • Ottestad, I.1    Vogt, G.2    Retterstol, K.3
  • 23
    • 84872683246 scopus 로고    scopus 로고
    • Intake of oxidised fish oil does not affect circulating levels of oxidised LDL or inflammatory markers in healthy subjects
    • Ottestad I, Retterstol K, Myhrstad MC et al. Intake of oxidised fish oil does not affect circulating levels of oxidised LDL or inflammatory markers in healthy subjects. Nutr Metab Cardiovasc Dis 2013; 23: e3-4.
    • (2013) Nutr Metab Cardiovasc Dis , vol.23 , pp. e3-e4
    • Ottestad, I.1    Retterstol, K.2    Myhrstad, M.C.3
  • 24
    • 84865477877 scopus 로고    scopus 로고
    • Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects
    • Ottestad I, Hassani S, Borge GI et al. Fish oil supplementation alters the plasma lipidomic profile and increases long-chain PUFAs of phospholipids and triglycerides in healthy subjects. PLoS One 2012; 7: e42550.
    • (2012) PLoS One , vol.7 , pp. e42550
    • Ottestad, I.1    Hassani, S.2    Borge, G.I.3
  • 25
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical bayes methods for assessing differential expression in microarray experiments
    • Article3.
    • Smyth GK. Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 2004; 3: Article3.
    • (2004) Stat Appl Genet Mol Biol , vol.3
    • Smyth, G.K.1
  • 26
    • 18344396568 scopus 로고    scopus 로고
    • Minimum information about a microarray experiment (MIAME)-toward standards for microarray data
    • Brazma A, Hingamp P, Quackenbush J et al. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet 2001; 29: 365-71.
    • (2001) Nat Genet , vol.29 , pp. 365-371
    • Brazma, A.1    Hingamp, P.2    Quackenbush, J.3
  • 27
    • 0038052805 scopus 로고    scopus 로고
    • The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer
    • Vermeulen K, Van Bockstaele DR, Berneman ZN. The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer. Cell Prolif 2003; 36: 131-49.
    • (2003) Cell Prolif , vol.36 , pp. 131-149
    • Vermeulen, K.1    Van Bockstaele, D.R.2    Berneman, Z.N.3
  • 28
    • 67949089699 scopus 로고    scopus 로고
    • Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells
    • Bouwens M, van de Rest O, Dellschaft N et al. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. Am J Clin Nutr 2009; 90: 415-24.
    • (2009) Am J Clin Nutr , vol.90 , pp. 415-424
    • Bouwens, M.1    van de Rest, O.2    Dellschaft, N.3
  • 29
    • 84855162522 scopus 로고    scopus 로고
    • Human nutrigenomics of gene regulation by dietary fatty acids
    • Afman LA, Muller M. Human nutrigenomics of gene regulation by dietary fatty acids. Prog Lipid Res 2012; 51: 63-70.
    • (2012) Prog Lipid Res , vol.51 , pp. 63-70
    • Afman, L.A.1    Muller, M.2
  • 30
    • 0031805395 scopus 로고    scopus 로고
    • Multiplication and death-type of leukemia cell lines exposed to very long-chain polyunsaturated fatty acids
    • Finstad HS, Myhrstad MC, Heimli H et al. Multiplication and death-type of leukemia cell lines exposed to very long-chain polyunsaturated fatty acids. Leukemia 1998; 12: 921-9.
    • (1998) Leukemia , vol.12 , pp. 921-929
    • Finstad, H.S.1    Myhrstad, M.C.2    Heimli, H.3
  • 31
    • 58849102749 scopus 로고    scopus 로고
    • DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis
    • Jakobsen CH, Storvold GL, Bremseth H et al. DHA induces ER stress and growth arrest in human colon cancer cells: associations with cholesterol and calcium homeostasis. J Lipid Res 2008; 49: 2089-100.
    • (2008) J Lipid Res , vol.49 , pp. 2089-2100
    • Jakobsen, C.H.1    Storvold, G.L.2    Bremseth, H.3
  • 32
    • 9744230664 scopus 로고    scopus 로고
    • Conjugated docosahexaenoic acid is a potent inducer of cell cycle arrest and apoptosis and inhibits growth of colo 201 human colon cancer cells
    • Danbara N, Yuri T, Tsujita-Kyutoku M et al. Conjugated docosahexaenoic acid is a potent inducer of cell cycle arrest and apoptosis and inhibits growth of colo 201 human colon cancer cells. Nutr Cancer 2004; 50: 71-9.
    • (2004) Nutr Cancer , vol.50 , pp. 71-79
    • Danbara, N.1    Yuri, T.2    Tsujita-Kyutoku, M.3
  • 33
  • 34
    • 10444226462 scopus 로고    scopus 로고
    • ER stress and the unfolded protein response
    • Schroder M, Kaufman RJ. ER stress and the unfolded protein response. Mutat Res 2005; 569: 29-63.
    • (2005) Mutat Res , vol.569 , pp. 29-63
    • Schroder, M.1    Kaufman, R.J.2
  • 35
    • 84872462504 scopus 로고    scopus 로고
    • Integration of autophagy, proteasomal degradation, unfolded protein response and apoptosis
    • Benbrook DM, Long A. Integration of autophagy, proteasomal degradation, unfolded protein response and apoptosis. Exp Oncol 2012; 34: 286-97.
    • (2012) Exp Oncol , vol.34 , pp. 286-297
    • Benbrook, D.M.1    Long, A.2
  • 36
    • 84866544628 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response in aging and age-related diseases
    • Brown MK, Naidoo N. The endoplasmic reticulum stress response in aging and age-related diseases. Front Physiol 2012; 3: 263.
    • (2012) Front Physiol , vol.3 , pp. 263
    • Brown, M.K.1    Naidoo, N.2
  • 37
    • 77952675374 scopus 로고    scopus 로고
    • ER stress in cardiovascular disease
    • Minamino T, Kitakaze M. ER stress in cardiovascular disease. J Mol Cell Cardiol 2010; 48: 1105-10.
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 1105-1110
    • Minamino, T.1    Kitakaze, M.2
  • 38
    • 33644858343 scopus 로고    scopus 로고
    • The unfolded protein response: a stress signaling pathway critical for health and disease
    • Zhang K, Kaufman RJ. The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 2006; 66: S102-9.
    • (2006) Neurology , vol.66 , pp. S102-S109
    • Zhang, K.1    Kaufman, R.J.2
  • 39
    • 0034598991 scopus 로고    scopus 로고
    • The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway
    • van Laar T, Schouten T, Hoogervorst E, van Eck M, van der Eb AJ, Terleth C. The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway. FEBS Lett 2000; 469: 123-31.
    • (2000) FEBS Lett , vol.469 , pp. 123-131
    • van Laar, T.1    Schouten, T.2    Hoogervorst, E.3    van Eck, M.4    van der Eb, A.J.5    Terleth, C.6
  • 40
    • 84879402032 scopus 로고    scopus 로고
    • Plasma Fatty Acid ratios affect blood gene expression profiles - a cross-sectional study of the norwegian women and cancer post-genome cohort
    • Olsen KS, Fenton C, Froyland L, Waaseth M, Paulssen RH, Lund E. Plasma Fatty Acid ratios affect blood gene expression profiles - a cross-sectional study of the norwegian women and cancer post-genome cohort. PLoS One 2013; 8: e67270.
    • (2013) PLoS One , vol.8 , pp. e67270
    • Olsen, K.S.1    Fenton, C.2    Froyland, L.3    Waaseth, M.4    Paulssen, R.H.5    Lund, E.6
  • 41
    • 77951214016 scopus 로고    scopus 로고
    • Mammalian autophagy: core molecular machinery and signaling regulation
    • Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol 2010; 22: 124-31.
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 124-131
    • Yang, Z.1    Klionsky, D.J.2
  • 42
    • 65949095803 scopus 로고    scopus 로고
    • Autophagy regulates lipid metabolism
    • Singh R, Kaushik S, Wang Y et al. Autophagy regulates lipid metabolism. Nature 2009; 458: 1131-5.
    • (2009) Nature , vol.458 , pp. 1131-1135
    • Singh, R.1    Kaushik, S.2    Wang, Y.3
  • 43
    • 65449132536 scopus 로고    scopus 로고
    • Age-associated mitochondrial dysfunction in skeletal muscle: contributing factors and suggestions for long-term interventions
    • Huang JH, Hood DA. Age-associated mitochondrial dysfunction in skeletal muscle: contributing factors and suggestions for long-term interventions. IUBMB Life 2009; 61: 201-14.
    • (2009) IUBMB Life , vol.61 , pp. 201-214
    • Huang, J.H.1    Hood, D.A.2
  • 44
    • 57649194935 scopus 로고    scopus 로고
    • Oxidant-induced changes in mitochondria and calcium dynamics in the pathophysiology of Alzheimer's disease
    • Gibson GE, Karuppagounder SS, Shi Q. Oxidant-induced changes in mitochondria and calcium dynamics in the pathophysiology of Alzheimer's disease. Ann N Y Acad Sci 2008; 1147: 221-32.
    • (2008) Ann N Y Acad Sci , vol.1147 , pp. 221-232
    • Gibson, G.E.1    Karuppagounder, S.S.2    Shi, Q.3
  • 45
    • 0033610079 scopus 로고    scopus 로고
    • Gene expression profile of aging and its retardation by caloric restriction
    • Lee CK, Klopp RG, Weindruch R, Prolla TA. Gene expression profile of aging and its retardation by caloric restriction. Science 1999; 285: 1390-3.
    • (1999) Science , vol.285 , pp. 1390-1393
    • Lee, C.K.1    Klopp, R.G.2    Weindruch, R.3    Prolla, T.A.4
  • 46
    • 26844558334 scopus 로고    scopus 로고
    • Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
    • Nisoli E, Tonello C, Cardile A et al. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 2005; 310: 314-7.
    • (2005) Science , vol.310 , pp. 314-317
    • Nisoli, E.1    Tonello, C.2    Cardile, A.3
  • 47
    • 77956588511 scopus 로고    scopus 로고
    • Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers
    • Bøhn SK, Myhrstad MC, Thoresen M et al. Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers. BMC Med 2010; 8: 54.
    • (2010) BMC Med , vol.8 , pp. 54
    • Bøhn, S.K.1    Myhrstad, M.C.2    Thoresen, M.3
  • 48
    • 0142166332 scopus 로고    scopus 로고
    • Targeting HIF-1 for cancer therapy
    • Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3: 721-32.
    • (2003) Nat Rev Cancer , vol.3 , pp. 721-732
    • Semenza, G.L.1
  • 49
    • 84865441790 scopus 로고    scopus 로고
    • Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial
    • Schmidt S, Stahl F, Mutz KO, Scheper T, Hahn A, Schuchardt JP. Different gene expression profiles in normo- and dyslipidemic men after fish oil supplementation: results from a randomized controlled trial. Lipids Health Dis 2012; 11: 105.
    • (2012) Lipids Health Dis , vol.11 , pp. 105
    • Schmidt, S.1    Stahl, F.2    Mutz, K.O.3    Scheper, T.4    Hahn, A.5    Schuchardt, J.P.6
  • 50
    • 84861335424 scopus 로고    scopus 로고
    • Transcriptome-based identification of antioxidative gene expression after fish oil supplementation in normo- and dyslipidemic men
    • Schmidt S, Stahl F, Mutz KO, Scheper T, Hahn A, Schuchardt JP. Transcriptome-based identification of antioxidative gene expression after fish oil supplementation in normo- and dyslipidemic men. Nutr Metab 2012; 9: 45.
    • (2012) Nutr Metab , vol.9 , pp. 45
    • Schmidt, S.1    Stahl, F.2    Mutz, K.O.3    Scheper, T.4    Hahn, A.5    Schuchardt, J.P.6
  • 51
    • 84870922416 scopus 로고    scopus 로고
    • Regulation of lipid metabolism-related gene expression in whole blood cells of normo- and dyslipidemic men after fish oil supplementation
    • Schmidt S, Willers J, Stahl F et al. Regulation of lipid metabolism-related gene expression in whole blood cells of normo- and dyslipidemic men after fish oil supplementation. Lipids Health Dis 2012; 11: 172.
    • (2012) Lipids Health Dis , vol.11 , pp. 172
    • Schmidt, S.1    Willers, J.2    Stahl, F.3
  • 52
    • 84870465239 scopus 로고    scopus 로고
    • Transcriptomic and metabolomic signatures of an n-3 polyunsaturated fatty acids supplementation in a normolipidemic/normocholesterolemic Caucasian population
    • Rudkowska I, Paradis AM, Thifault E et al. Transcriptomic and metabolomic signatures of an n-3 polyunsaturated fatty acids supplementation in a normolipidemic/normocholesterolemic Caucasian population. J Nutr Biochem 2013; 24: 54-61.
    • (2013) J Nutr Biochem , vol.24 , pp. 54-61
    • Rudkowska, I.1    Paradis, A.M.2    Thifault, E.3
  • 53
    • 84860184035 scopus 로고    scopus 로고
    • Effects of DHA-rich n-3 fatty acidsupplementation on gene expression in blood mononuclear leukocytes: the OmegAD study
    • Vedin I, Cederholm T, Freund-Levi Y et al. Effects of DHA-rich n-3 fatty acidsupplementation on gene expression in blood mononuclear leukocytes: the OmegAD study. PLoS One 2012; 7: e35425.
    • (2012) PLoS One , vol.7 , pp. e35425
    • Vedin, I.1    Cederholm, T.2    Freund-Levi, Y.3
  • 54
    • 33645376731 scopus 로고    scopus 로고
    • Nutrigenomics: from molecular nutrition to prevention of disease
    • Afman L, Muller M. Nutrigenomics: from molecular nutrition to prevention of disease. J Am Diet Assoc 2006; 106: 569-76.
    • (2006) J Am Diet Assoc , vol.106 , pp. 569-576
    • Afman, L.1    Muller, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.