Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death

Journal of Membrane Biology

Volumn 209, Issue 1, 2006, Pages 21-29

  Okada, Y ^a   Shimizu, T ^a   Maeno, E ^a   Tanabe, S ^a   Wang, X ^a   Takahashi, N ^a  

^a NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Anion channel; Anti cancer drug; Apoptosis; Apoptotic volume decrease; Ischemia reperfusion injury; VSOR Cl channel

Indexed keywords

4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 5 NITRO 2 (3 PHENYLPROPYLAMINO)BENZOIC ACID; ANTINEOPLASTIC AGENT; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CHLORIDE ION; CISPLATIN; CLC3 PROTEIN; DEATH RECEPTOR; FLUFENAMIC ACID; GLIBENCLAMIDE; MEMBRANE PROTEIN; PHLORETIN; POTASSIUM ION; SCAVENGER; UNCLASSIFIED DRUG; VOLUME SENSITIVE CHLORIDE CHANNEL; VOLUME SENSITIVE OUTWARDLY RECTIFYING CHLORIDE CHANNEL;

ANIMAL CELL; APOPTOSIS; APOPTOTIC VOLUME DECREASE; BRAIN CELL; CANCER CELL; CELL SWELLING; CELL TYPE; CELL VOLUME; CHLORIDE CONDUCTANCE; CHLORIDE TRANSPORT; DEGENERATIVE DISEASE; EPITHELIUM CELL; HEART MUSCLE CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; ORGANOGENESIS; POTASSIUM TRANSPORT; REPERFUSION INJURY; REVIEW; SOMATIC CELL;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; 4-ACETAMIDO-4'-ISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID; ANIMALS; APOPTOSIS; CELL DEATH; CELL SIZE; CHLORIDE CHANNELS; HUMANS; MYOCYTES, CARDIAC; STAUROSPORINE;

EID: 33646586354     PISSN: 00222631     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00232-005-0836-6     Document Type: Review

References (68)

1. Araki, T., Hayashi, M., Watanabe, N., Kanuka, H., Yoshino, J., Miura, M., Saruta, T. 2002. Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death. Biochem. Biophys. Res. Commun. 290:1275-1281
2. - channel gene. J. Physiol. 545:207-216
3. Barriere, H., Poujeol, C., Tauc, M., Blasi, J.M., Counillon, L., Poujeol, P. 2001. CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts. Am. J. Physiol. 281:C810-C824
4. Bortner, C.D., Cidlowski, J.A. 1996. Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes. Am. J. Physiol. 271:C950-C961
5. Bortner, C.D., Cidlowski, J.A. 2002. Cellular mechanisms for the repression of apoptosis. Annu. Rev. Pharmacol. Toxicol. 42:259-281
6. + influx is required for volume loss during programmed cell death. J. Biol. Chem. 278:39176-39184
7. - current elicited by beta1 integral stretch in rabbit ventricular myocytes. J. Gen. Physiol. 124:273-287
8. Buettner, R., Papoutsoglou, G., Scemes, E., Spray, D.C., Dermietzel, R. 2000. Evidence for secretory pathway localization of a voltage-dependent anion channel isoform. Proc. Natl. Acad. Sci. USA 97:3201-3206
9. Cannon, C.L., Basavappa, S., Strange, K. 1998. Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel. Am. J. Physiol. 275:C416-C422
10. Cannon, C.L., Kowalski, M.P., Stopak, K.S., Pier, G.B. 2003. Pseudomonas aeruginosa-induced apoptosis is defective in respiratory epithelial cells expressing mutant cystic fibrosis transmembrane conductance regulator. Am. J. Respir. Cell Mol. Biol. 29:188-197
11. - channels associated with ciliary epithelial homologue of pICln. Am. J. Physiol. 268:C572-C579
12. d'Anglemont de Tassigny, A., Souktani, R., Henry, P., Ghaleh, B., Berdeaux, A. 2004. Volume-sensitive chloride channels (IC vol) mediate doxorubicin-induced apoptosis through apoptotic volume decrease in cardiomyocytes. Fundam. Clin. Pharmacol. 18:531-538
13. Dermietzel, R., Hwang, T.K., Buettner, R., Hofer, A., Dotzler, E., Kremer, M., Deutzmann, R., Thinnes, F.P., Fishman, G.I., Spray, D.C., Siemen, D. 1994. Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes. Proc. Natl. Acad. Sci. USA 91:499-503
14. Dong, Z., Wang, J., Zhong, Q. 2003. Postmitochondrial regulation of apoptosis by bicarbonate. Exp. Cell Res. 288:301-312
15. Duan, D., Winter, C., Cowley, S., Hume, J.R., Horowitz, B. 1997. Molecular identification of a volume-regulated chloride channel. Nature 390:417-421
16. Dupéré-Minier, G., Hamelin, C., Desharnais, P., Bernier, J. 2004. Apoptotic volume decrease, pH acidification and chloride channel activation during apoptosis requires CD45 expression in HPB-ALL T cells. Apoptosis 9:543-551
17. Dutta, A.K., Sabirov, R.Z., Uramoto, H., Okada, Y. 2004. Role of ATP-conductive anion channel in ATP release from neonatal rat cardiomyocytes in ischemic or hypoxic conditions. J. Physiol. 559:799-812
18. Eggermont, J. 2004. Calcium-activated chloride channels: (un)-known, (un)loved? Proc. Am. Thorac. Soc. 1:22-27
19. Elble, R.C., Pauli, B.U. 2001. Tumor suppression by a proapoptotic calcium-activated chloride channel in mammary epithelium. J. Biol. Chem. 276:40510-40517
20. Elinder, F., Akanda, N., Tofighi, R., Shimizu, S., Tsujimoto, Y., Orrenius, S., Ceccatelli, S. 2005. Opening of plasma membrane voltage-dependent anion channels (VDAC) precedes caspase activation in neuronal apoptosis induced by toxic stimuli. Cell Death Differ. 12:1134-1140
21. - channels. Br. J. Pharmacol. 133:1096-1106
22. Fujita, H., Ishizaki, Y., Yanagisawa, A., Morita, I., Murota, S.I., Ishikawa, K. 1999. Possible involvement of a chloride-bicarbonate exchanger in apoptosis of endothelial cells and cardiomyocytes. Cell Biol. Int. 23:241-249
23. Fujita, H., Yanagisawa, A., Ishikawa, K. 1997. Suppressive effect of a chloride bicarbonate exchanger inhibitor on staurosporine-induced apoptosis of endothelial cells. Heart Vessels (Suppl.) 12:84-88
24. - channel in mouse ventricular cardiomyocytes. Cell. Physiol. Biochem. 14:213-224
25. Gottlieb, R.A., Dosanjh, A. 1996. Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: possible relevance to cystic fibrosis. Proc. Natl. Acad. Sci. USA 93:3587-3591
26. Gulbins, E., Jekle, A., Ferlinz, K., Grassme, H., Lang, F. 2000. Physiology of apoptosis. Am. J. Physiol. 279:F605-F615
27. Hortelano, S., Zeini, M., Castrillo, A., Alvarez, A.M., Bosca, L. 2002. Induction of apoptosis by nitric oxide in macrophages is independent of apoptotic volume decrease. Cell Death Differ. 9:643-650
28. Inoue, H., Ohtaki, H., Shioda, S., Okada, Y. 2005. Chloride channel blockers attenuate delayed neuronal cell death induced by transient forebrain ischemia. Jpn. J. Physiol. 55:S149
29. - channel in cisplatin-induced apoptosis in human epidermoid cancer cells. J. Membrane Biol. 205:139-145
30. Jackson, P.S., Morrison, R., Strange, K. 1994. The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding. Am. J. Physiol. 267:C1203-C1209
31. - and ATP. Am. J. Physiol. 270:C57-C66
32. - channels in the mechanism of apoptosis induced by cyclosporin A in a human hepatoma cell line. Biochem. Biophys. Res. Commun. 309:291-297
33. Lepple-Wienhues, A., Szabo, I., Laun, T., Kaba, N.K., Gulbins, E., Lang., F. 1998. The tyrosine kinase p56lck mediates activation of swelling-induced chloride channels in lymphocytes. J. Cell Biol. 141:281-286
34. - channels by dual mechanisms. Am. J. Physiol. 275:C343-C351
35. Maeno, E., Ishizaki, Y., Kanaseki, T., Hazama, A., Okada, Y. 2000. Normotonic cell shrinkage due to disordered volume regulation is an early prerequisite to apoptosis. Proc. Natl. Acad. Sci. USA 97:9487-9492
36. Meng, X.J., Carruth, M.W., Weinman, S.A. 1997. Leukotriene D4 activates a chloride conductance in hepatocytes from lipopolysaccharide-treated rats. J. Clin. Invest. 99:2915-2922
37. Meyer, K., Korbmacher, C. 1996. Cell swelling activates ATP-dependent voltage-gated chloride channels in M-1 mouse cortical collecting duct cells. J. Gen. Physiol. 108:177-193
38. 2+-induced erythrocyte 'apoptosis'. Cell. Physiol. Biochem. 14:241-248
39. Nietsch, H.H., Roe, M.W., Fiekers, J.F., Moore, A.L., Lidofsky, S.D. 2000. Activation of potassium and chloride channels by tumor necrosis factor α. Role in liver cell death. J. Biol. Chem. 275:20556-20561
40. Nilius, B, Eggermont, J., Voets, T., Buyse, G., Manolopoulos, V., Droogmans, G. 1997. Properties of volume-regulated anion channels in mammalian cells. Prog. Biophys. Mol. Biol. 68:69-119
41. - channels in human epithelial cells. Jpn. J. Physiol. 44:(Suppl. 2)S77-S79
42. Okada, Y. 1997. Volume expansion-sensing outward rectifier Cl channel: A fresh start to the molecular identity and volume sensor. Am. J. Physiol. 273:C755-C789
43. Okada, Y. 2004. Ion channels and transporters involved in cell volume regulation and sensor mechanisms. Cell Biochem. Biophys. 41:233-258
44. Okada, Y., Maeno, E. 2001. Apoptosis, cell volume regulation and volume-regulatory chloride channels. Comp. Biochem. Physiol. Part A. 130:377-383
45. Okada, Y., Maeno, E., Shimizu, T., Dezaki, K., Wang, J., Morishima, S. 2001. Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J. Physiol. 532:3-16
46. Okada, Y., Maeno, E., Shimizu, T., Manabe, K., Mori, S., Nabekura, T. 2004. Dual roles of plasmalemmal chloride channels in induction of cell death. Pfluegers Arch. Eur. J. Physiol. 448:287-295
47. O'Reilly, N., Xia, Z., Fiander, H., Tauskela, J., Small, DL. 2002. Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells. Brain Res. 943:245-256
48. Porcelli, A.M., Ghelli, A., Zanna, C., Valente, P., Ferroni, S., Rugolo, M. 2003. Staurosporine induces apoptotic volume decrease (AVD) in ECV304 cells. Ann. N. Y. Acad. Sci. 1010:342-346
49. - conductance. Cell Death Differ. 11:655-662
50. - efflux impairment in hematopoietic cell apoptosis. FASEB J. 13:1711-1723
51. Sabirov, R.Z., Sheiko, T., Liu, H., Deng, D., Okada, Y., Craigen, W.J. 2006. Genetic demonstration that the plasma membrane maxi-anion channel and voltage-dependent anion channels (VDACS) are unrelated proteins. J. Biol. Chem. 281:1897-1904
52. Schumann, M.A., Gardner, P., Raffin, T.A. 1993. Recombinant human tumor necrosis factor alpha induces calcium oscillation and calcium-activated chloride current in human neutrophils. The role of calcium/calmodulin-dependent protein kinase. J. Biol. Chem. 268:2134-2140
53. Shen, M.R., Droogmans, G., Eggermont, J., Voets, T., Ellory, J.C., Nilius, B. 2000. Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells. J. Physiol. 529:385-394
54. - channel. Proc. Natl. Acad. Sci. USA 101:6770-6773
55. Small, D.L., Tauskela, J., Xia, Z. 2002. Role for chloride but not potassium channels in apoptosis in primary rat cortical cultures. Neurosci. Lett. 334:95-98
56. Souktani, R., Berdeaux, A., Ghaleh, B., Giudicelli, J.F., Guize, L., Le Heuzey, J.Y., Henry, P. 2000. Induction of apoptosis using sphingolipids activates a chloride current in Xenopus laevis oocytes. Am. J. Physiol. 279:C158-C165
57. Steinacker, P., Awni, L.A., Becker, S., Cole, T., Reymann, S., Hesse, D., Kratzin, H.D., Morris-Wortmann, C., Schwarzer, C., Thinnes, F.P., Hilschmann, N. 2000. The plasma membrane of Xenopus laevis oocytes contains voltage-dependent anion-selective porin channels. Int. J. Biochem. Cell Biol. 32:225-234
58. Stobrawa, S.M., Breiderhoff, T., Takamori, S., Engel, D., Schweizer, M., Zdebik, A.A., Bosl, M.R., Ruether, K., Jahn, H., Draguhn, A., Jahn, R., Jentsch, T.J. 2001. Disruption of ClC-3, a chloride channel expressed on synaptic vesicles, leads to a loss of the hippocampus. Neuron 29:185-196
59. Strange, K., Emma, F., Jackson, P.S. 1996. Cellular and molecular physiology of volume-sensitive anion channels. Am. J. Physiol. 270:C711-C730
60. Szabo, I., Lepple-Wienhues, A., Kaba, K.N., Zoratti, M., Gulbins, E., Lang, F. 1998. Tyrosine kinase-dependent activation of a chloride channel in CD95-induced apoptosis in T lymphocytes. Proc. Natl. Acad. Sci. USA 95:6169-6174
61. - channel blockers in mouse cardiomyocytes. Cell. Physiol. Biochem. 15:263-270
62. --independent rescue from apoptosis by stilbene derivatives in rat cardiomyocytes. FEBS Lett. 579:517-522
63. - channels in host epithelial cells. Pflügers Arch. Eur. J. Physiol. 447:23-28
64. 2 signals chloride channel activation in cell volume regulation and cell proliferation. J. Biol. Chem. 279:13301-1334
65. Wang, X., Takahashi, N., Uramoto, H., Okada, Y. 2005. Chloride channel inhibition prevents ROS-dependent apoptosis induced by ischemia-reperfusion in mouse cardiomyocytes. Cell. Physiol. Biochem. 16:147-154
66. Wei, L., Xiao, A.Y., Jin, C., Yang, A., Lu, Z.Y., Yu, S.P. 2004. Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. Pfluegers Arch. Eur. J. Physiol. 448:325-334
67. Wondergem, R., Gong, W., Monen, S.H., Dooley, S.N., Gonce, J.L., Conner, T.D., Houser, M., Ecay, T.W., Ferslew, K.E. 2001. Blocking swelling-activated chloride current inhibits mouse liver cell proliferation. J. Physiol. 532:661-672
68. Zamaraeva, M.V., Sabirov, R.Z., Maeno, E., Ando-Akatsuka, Y., Bessonova, S.V., Okada, Y. 2005. Cells die with increased cytosolic ATP during apoptosis: A bioluminescence study with intracellular luciferase. Cell Death Differ. 12:1390-1397