메뉴 건너뛰기




Volumn 84, Issue 4, 2010, Pages 1847-1855

Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON;

EID: 75449108141     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01317-09     Document Type: Article
Times cited : (45)

References (38)
  • 2
    • 62549085229 scopus 로고    scopus 로고
    • Baskin, C. R., H. Bielefeldt-Ohmann, T. M. Tumpey, P. J. Sabourin, J. P. Long, A. Garcia-Sastre, A. E. Tolnay, R. Albrecht, J. A. Pyles, P. H. Olson, L. D. Aicher, E. R. Rosenzweig, K. Murali-Krishna, E. A. Clark, M. S. Kotur, J. L. Fornek, S. Proll, R. E. Palermo, C. L. Sabourin, and M. G. Katze. 2009. Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus. Proc. Natl. Acad. Sci. U. S. A. 106:3455-3460.
    • Baskin, C. R., H. Bielefeldt-Ohmann, T. M. Tumpey, P. J. Sabourin, J. P. Long, A. Garcia-Sastre, A. E. Tolnay, R. Albrecht, J. A. Pyles, P. H. Olson, L. D. Aicher, E. R. Rosenzweig, K. Murali-Krishna, E. A. Clark, M. S. Kotur, J. L. Fornek, S. Proll, R. E. Palermo, C. L. Sabourin, and M. G. Katze. 2009. Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus. Proc. Natl. Acad. Sci. U. S. A. 106:3455-3460.
  • 3
    • 0346102606 scopus 로고    scopus 로고
    • Safety and efficacy of live attenuated, cold-adapted, influenza vaccine-trivalent
    • Belshe, R. B., and P. M. Mendelman. 2003. Safety and efficacy of live attenuated, cold-adapted, influenza vaccine-trivalent. Immunol. Allergy Clin. N. Am. 23:745-767.
    • (2003) Immunol. Allergy Clin. N. Am , vol.23 , pp. 745-767
    • Belshe, R.B.1    Mendelman, P.M.2
  • 4
    • 0026580765 scopus 로고    scopus 로고
    • Bender, B. S., T. Croghan, L. Zhang, and P. A. Small, Jr. 1992. Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge. J. Exp. Med. 175:1143-1145.
    • Bender, B. S., T. Croghan, L. Zhang, and P. A. Small, Jr. 1992. Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge. J. Exp. Med. 175:1143-1145.
  • 5
    • 67349182104 scopus 로고    scopus 로고
    • Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes
    • Brown, L. E., and A. Kelso. 2009. Prospects for an influenza vaccine that induces cross-protective cytotoxic T lymphocytes. Immunol. Cell Biol. 87: 300-308.
    • (2009) Immunol. Cell Biol , vol.87 , pp. 300-308
    • Brown, L.E.1    Kelso, A.2
  • 6
    • 66149099169 scopus 로고    scopus 로고
    • Vaccine decisions loom for new flu strain
    • Butler, D. 2009. Vaccine decisions loom for new flu strain. Nature 459:144-145.
    • (2009) Nature , vol.459 , pp. 144-145
    • Butler, D.1
  • 7
    • 0442323299 scopus 로고    scopus 로고
    • Influenza virus: Immunity and vaccination strategies: comparison of the immune response to inactivated and live, attenuated influenza vaccines
    • Cox, R. J., K. A. Brokstad, and P. Ogra. 2004. Influenza virus: immunity and vaccination strategies: comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scand. J. Immunol. 59:1-15.
    • (2004) Scand. J. Immunol , vol.59 , pp. 1-15
    • Cox, R.J.1    Brokstad, K.A.2    Ogra, P.3
  • 8
    • 18344362061 scopus 로고    scopus 로고
    • Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation
    • Curtsinger, J. M., J. O. Valenzuela, P. Agarwal, D. Lins, and M. F. Mescher. 2005. Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation. J. Immunol. 174:4465- 4469.
    • (2005) J. Immunol , vol.174 , pp. 4465-4469
    • Curtsinger, J.M.1    Valenzuela, J.O.2    Agarwal, P.3    Lins, D.4    Mescher, M.F.5
  • 9
    • 1842536901 scopus 로고    scopus 로고
    • Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 protein
    • Falcon, A. M., R. M. Marion, T. Zurcher, P. Gomez, A. Portela, A. Nieto, and J. Ortin. 2004. Defective RNA replication and late gene expression in temperature-sensitive influenza viruses expressing deleted forms of the NS1 protein. J. Virol. 78:3880-3888.
    • (2004) J. Virol , vol.78 , pp. 3880-3888
    • Falcon, A.M.1    Marion, R.M.2    Zurcher, T.3    Gomez, P.4    Portela, A.5    Nieto, A.6    Ortin, J.7
  • 10
    • 8644243888 scopus 로고    scopus 로고
    • Immunogenicity and protection efficacy of replicationdeficient influenza A viruses with altered NS1 genes
    • Ferko, B., J. Stasakova, J. Romanova, C. Kittel, S. Sereinig, H. Katinger, and A. Egorov. 2004. Immunogenicity and protection efficacy of replicationdeficient influenza A viruses with altered NS1 genes. J. Virol. 78:13037-13045.
    • (2004) J. Virol , vol.78 , pp. 13037-13045
    • Ferko, B.1    Stasakova, J.2    Romanova, J.3    Kittel, C.4    Sereinig, S.5    Katinger, H.6    Egorov, A.7
  • 12
    • 67249138142 scopus 로고    scopus 로고
    • Fraser, C., C. A. Donnelly, S. Cauchemez, W. P. Hanage, M. D. Van Kerkhove, T. D. Hollingsworth, J. Griffin, R. F. Baggaley, H. E. Jenkins, E. J. Lyons, T. Jombart, W. R. Hinsley, N. C. Grassly, F. Balloux, A. C. Ghani, N. M. Ferguson, A. Rambaut, O. G. Pybus, H. Lopez-Gatell, C. M. Apluche-Aranda, I. B. Chapela, E. P. Zavala, D. M. Guevara, F. Checchi, E. Garcia, S. Hugonnet, and C. Roth. 2009. Pandemic potential of a strain of influenza A (H1N1): early findings. Science 324:1557-1561.
    • Fraser, C., C. A. Donnelly, S. Cauchemez, W. P. Hanage, M. D. Van Kerkhove, T. D. Hollingsworth, J. Griffin, R. F. Baggaley, H. E. Jenkins, E. J. Lyons, T. Jombart, W. R. Hinsley, N. C. Grassly, F. Balloux, A. C. Ghani, N. M. Ferguson, A. Rambaut, O. G. Pybus, H. Lopez-Gatell, C. M. Apluche-Aranda, I. B. Chapela, E. P. Zavala, D. M. Guevara, F. Checchi, E. Garcia, S. Hugonnet, and C. Roth. 2009. Pandemic potential of a strain of influenza A (H1N1): early findings. Science 324:1557-1561.
  • 15
    • 33749004778 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling
    • Hale, B. G., D. Jackson, Y. H. Chen, R. A. Lamb, and R. E. Randall. 2006. Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. Proc. Natl. Acad. Sci. U. S. A. 103:14194-14199.
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , pp. 14194-14199
    • Hale, B.G.1    Jackson, D.2    Chen, Y.H.3    Lamb, R.A.4    Randall, R.E.5
  • 16
    • 54449099369 scopus 로고    scopus 로고
    • The multifunctional NS1 protein of influenza A viruses
    • Hale, B. G., R. E. Randall, J. Ortin, and D. Jackson. 2008. The multifunctional NS1 protein of influenza A viruses. J. Gen. Virol. 89:2359-2376.
    • (2008) J. Gen. Virol , vol.89 , pp. 2359-2376
    • Hale, B.G.1    Randall, R.E.2    Ortin, J.3    Jackson, D.4
  • 17
    • 0036118394 scopus 로고    scopus 로고
    • Recombinant vaccinia virus-induced T-cell immunity: Quantitation of the response to the virus vector and the foreign epitope
    • Harrington, L. E., R. Most Rv, J. L. Whitton, and R. Ahmed. 2002. Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J. Virol. 76:3329-3337.
    • (2002) J. Virol , vol.76 , pp. 3329-3337
    • Harrington, L.E.1    Most Rv, R.2    Whitton, J.L.3    Ahmed, R.4
  • 18
    • 0025340196 scopus 로고
    • Analysis of influenza A virus temperature-sensitive mutants with mutations in RNA segment 8
    • Hatada, E., M. Hasegawa, K. Shimizu, M. Hatanaka, and R. Fukuda. 1990. Analysis of influenza A virus temperature-sensitive mutants with mutations in RNA segment 8. J. Gen. Virol. 71(Pt. 6):1283-1292.
    • (1990) J. Gen. Virol , vol.71 , Issue.PART. 6 , pp. 1283-1292
    • Hatada, E.1    Hasegawa, M.2    Shimizu, K.3    Hatanaka, M.4    Fukuda, R.5
  • 19
    • 33644837684 scopus 로고    scopus 로고
    • Cutting edge: The direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection
    • Havenar-Daughton, C., G. A. Kolumam, and K. Murali-Krishna. 2006. Cutting edge: the direct action of type I IFN on CD4 T cells is critical for sustaining clonal expansion in response to a viral but not a bacterial infection. J. Immunol. 176:3315-3319.
    • (2006) J. Immunol , vol.176 , pp. 3315-3319
    • Havenar-Daughton, C.1    Kolumam, G.A.2    Murali-Krishna, K.3
  • 21
    • 33646497012 scopus 로고    scopus 로고
    • Influenza virus NS1 protein protects against lymphohematopoietic pathogenesis in an in vivo mouse model
    • Hyland, L., R. Webby, M. R. Sandbulte, B. Clarke, and S. Hou. 2006. Influenza virus NS1 protein protects against lymphohematopoietic pathogenesis in an in vivo mouse model. Virology 349:156-163.
    • (2006) Virology , vol.349 , pp. 156-163
    • Hyland, L.1    Webby, R.2    Sandbulte, M.R.3    Clarke, B.4    Hou, S.5
  • 22
    • 41949123710 scopus 로고    scopus 로고
    • A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity
    • Jackson, D., M. J. Hossain, D. Hickman, D. R. Perez, and R. A. Lamb. 2008. A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity. Proc. Natl. Acad. Sci. U. S. A. 105: 4381-4386.
    • (2008) Proc. Natl. Acad. Sci. U. S. A , vol.105 , pp. 4381-4386
    • Jackson, D.1    Hossain, M.J.2    Hickman, D.3    Perez, D.R.4    Lamb, R.A.5
  • 23
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T-cell differentiation
    • Kaech, S. M., S. Hemby, E. Kersh, and R. Ahmed. 2002. Molecular and functional profiling of memory CD8 T-cell differentiation. Cell 111:837-851.
    • (2002) Cell , vol.111 , pp. 837-851
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 24
    • 24344478196 scopus 로고    scopus 로고
    • Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection
    • Kolumam, G. A., S. Thomas, L. J. Thompson, J. Sprent, and K. Murali-Krishna. 2005. Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J. Exp. Med. 202:637-650.
    • (2005) J. Exp. Med , vol.202 , pp. 637-650
    • Kolumam, G.A.1    Thomas, S.2    Thompson, L.J.3    Sprent, J.4    Murali-Krishna, K.5
  • 25
    • 33646478272 scopus 로고    scopus 로고
    • The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2′-5′ oligo(A) synthetase/RNase L pathway
    • Min, J. Y., and R. M. Krug. 2006. The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: inhibiting the 2′-5′ oligo(A) synthetase/RNase L pathway. Proc. Natl. Acad. Sci. U. S. A. 103: 7100-7105.
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , pp. 7100-7105
    • Min, J.Y.1    Krug, R.M.2
  • 26
    • 34247566514 scopus 로고    scopus 로고
    • A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis
    • Min, J. Y., S. Li, G. C. Sen, and R. M. Krug. 2007. A site on the influenza A virus NS1 protein mediates both inhibition of PKR activation and temporal regulation of viral RNA synthesis. Virology 363:236-243.
    • (2007) Virology , vol.363 , pp. 236-243
    • Min, J.Y.1    Li, S.2    Sen, G.C.3    Krug, R.M.4
  • 30
    • 19944419799 scopus 로고    scopus 로고
    • Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
    • Solorzano, A., R. J. Webby, K. M. Lager, B. H. Janke, A. Garcia-Sastre, and J. A. Richt. 2005. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J. Virol. 79: 7535-7543.
    • (2005) J. Virol , vol.79 , pp. 7535-7543
    • Solorzano, A.1    Webby, R.J.2    Lager, K.M.3    Janke, B.H.4    Garcia-Sastre, A.5    Richt, J.A.6
  • 31
    • 30444444679 scopus 로고    scopus 로고
    • Development of effective vaccines against pandemic influenza
    • Subbarao, K., B. R. Murphy, and A. S. Fauci. 2006. Development of effective vaccines against pandemic influenza. Immunity 24:5-9.
    • (2006) Immunity , vol.24 , pp. 5-9
    • Subbarao, K.1    Murphy, B.R.2    Fauci, A.S.3
  • 33
    • 35548976678 scopus 로고    scopus 로고
    • Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine
    • Vincent, A. L., W. Ma, K. M. Lager, B. H. Janke, R. J. Webby, A. Garcia-Sastre, and J. A. Richt. 2007. Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine. Vaccine 25: 7999-8009.
    • (2007) Vaccine , vol.25 , pp. 7999-8009
    • Vincent, A.L.1    Ma, W.2    Lager, K.M.3    Janke, B.H.4    Webby, R.J.5    Garcia-Sastre, A.6    Richt, J.A.7
  • 34
    • 0036891842 scopus 로고    scopus 로고
    • Functional replacement of the carboxy-terminal twothirds of the influenza A virus NS1 protein with short heterologous dimerization domains
    • Wang, X., C. F. Basler, B. R. Williams, R. H. Silverman, P. Palese, and A. Garcia-Sastre. 2002. Functional replacement of the carboxy-terminal twothirds of the influenza A virus NS1 protein with short heterologous dimerization domains. J. Virol. 76:12951-12962.
    • (2002) J. Virol , vol.76 , pp. 12951-12962
    • Wang, X.1    Basler, C.F.2    Williams, B.R.3    Silverman, R.H.4    Palese, P.5    Garcia-Sastre, A.6
  • 38
    • 0041402774 scopus 로고    scopus 로고
    • Cell-mediated immunity to respiratory virus infections
    • Woodland, D. L. 2003. Cell-mediated immunity to respiratory virus infections. Curr. Opin. Immunol. 15:430-435.
    • (2003) Curr. Opin. Immunol , vol.15 , pp. 430-435
    • Woodland, D.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.