메뉴 건너뛰기




Volumn 15, Issue 11, 2014, Pages 20449-20468

The effects of NAD+on apoptotic neuronal death and mitochondrial biogenesis and function after glutamate excitotoxicity

Author keywords

AIF; Apoptosis; Glutamate excitotoxicity; Ischemic stroke; Mitochondrial biogenesis

Indexed keywords

MITOCHONDRIAL DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; NUCLEAR RESPIRATORY FACTOR 1; APOPTOSIS INDUCING FACTOR; GLUTAMIC ACID;

EID: 84910132573     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms151120449     Document Type: Article
Times cited : (29)

References (49)
  • 1
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl, U.; Iadecola, C.; Moskowitz, M.A. Pathobiology of ischaemic stroke: An integrated view. Trends Neurosci. 1999, 22, 391-397
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 2
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi, D. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1, 623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.1
  • 3
    • 84865411082 scopus 로고    scopus 로고
    • The dynamic regulation of NAD+ metabolism in mitochondria. Trends Endocrinol
    • Stein, L.R.; Imai, S. The dynamic regulation of NAD+ metabolism in mitochondria. Trends Endocrinol. Metab. 2012, 23, 420-428.
    • (2012) Metab , vol.23 , pp. 420-428
    • Stein, L.R.1    Imai, S.2
  • 5
    • 34547413569 scopus 로고    scopus 로고
    • Sirtuin functions in health and disease.
    • Yamamoto, H.; Schoonjans, K.; Auwerx, J. Sirtuin functions in health and disease. Mol. Endocrinol. 2007, 21, 1745-1755.
    • (2007) Mol. Endocrinol , vol.21 , pp. 1745-1755
    • Yamamoto, H.1    Schoonjans, K.2    Auwerx, J.3
  • 6
    • 33747139670 scopus 로고    scopus 로고
    • Nampt/PBEF/Visfatin: A regulator of mammalian health and longevity?
    • Yang, H.; Lavu, S.; Sinclair, D.A. Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity? Exp. Gerontol. 2006, 41, 718-726.
    • (2006) Exp. Gerontol , vol.41 , pp. 718-726
    • Yang, H.1    Lavu, S.2    Sinclair, D.A.3
  • 7
    • 0347128279 scopus 로고    scopus 로고
    • Calorie restriction extends yeast life span by lowering the level of NADH
    • Lin, S.J.; Ford, E.; Haigis, M.; Liszt, G.; Guarente, L. Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev. 2004, 18, 12-16.
    • (2004) Genes Dev , vol.18 , pp. 12-16
    • Lin, S.J.1    Ford, E.2    Haigis, M.3    Liszt, G.4    Guarente, L.5
  • 9
    • 77953455149 scopus 로고    scopus 로고
    • Shear stress, SIRT1, and vascular homeostasis
    • Chen, Z.; Peng, I.C.; Cui, X.; Li, Y.S.; Chien, S.; Shyy, J.Y.J. Shear stress, SIRT1, and vascular homeostasis. PNAS 2010, 107, 10268-10273
    • (2010) PNAS , vol.107 , pp. 10268-10273
    • Chen, Z.1    Peng, I.C.2    Cui, X.3    Li, Y.S.4    Chien, S.5    Shyy, J.6
  • 12
    • 52449091282 scopus 로고    scopus 로고
    • Cellular NAD+ replenishment confers marked neuroprotection against ischemic cell death: Role of enhanced DNA repair
    • Wang, S.; Xing, Z.; Vosler, P.S.; Yin, H.; Li, W.; Zhang, F.; Signore, A.P.; Stetler, R.A.; Gao, Y.; Chen, J. Cellular NAD+ replenishment confers marked neuroprotection against ischemic cell death: Role of enhanced DNA repair. Stroke 2008, 39, 2587-2595.
    • (2008) Stroke , vol.39 , pp. 2587-2595
    • Wang, S.1    Xing, Z.2    Vosler, P.S.3    Yin, H.4    Li, W.5    Zhang, F.6    Signore, A.P.7    Stetler, R.A.8    Gao, Y.9    Chen, J.10
  • 13
    • 84155160707 scopus 로고    scopus 로고
    • Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models
    • Bi, J.; Li, H.; Ye, S.Q.; Ding, S. Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models. J. Neurochem. 2012, 120, 334-346.
    • (2012) J. Neurochem , vol.120 , pp. 334-346
    • Bi, J.1    Li, H.2    Ye, S.Q.3    Ding, S.4
  • 14
    • 84862776739 scopus 로고    scopus 로고
    • Administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia
    • Zheng, C.; Han, J.; Xia, W.; Shi, S.; Liu, J.; Ying, W. NAD+ administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia. Neurosci. Lett. 2012, 512, 67-71.
    • (2012) Neurosci. Lett , vol.512 , pp. 67-71
    • Zheng, C.1    Han, J.2    Xia, W.3    Shi, S.4    Liu, J.5    Ying, W.N.6
  • 15
    • 57649217303 scopus 로고    scopus 로고
    • Preventing NAD+ depletion protects neurons against excitotoxicity: Bioenergetic effects of mild mitochondrial uncoupling and caloric restriction
    • Liu, D.; Pitta, M.; Mattson, M.P. Preventing NAD+ depletion protects neurons against excitotoxicity: bioenergetic effects of mild mitochondrial uncoupling and caloric restriction. Ann. N. Y. Acad. Sci. 2008, 1147, 275-282.
    • (2008) Ann. N. Y. Acad. Sci , vol.1147 , pp. 275-282
    • Liu, D.1    Pitta, M.2    Mattson, M.P.3
  • 18
    • 19444364781 scopus 로고    scopus 로고
    • Poly(ADP-ribosyl)ation and stroke
    • Chiarugi, A. Poly(ADP-ribosyl)ation and stroke. Pharmacol. Res. 2005, 52, 15-24.
    • (2005) Pharmacol. Res , vol.52 , pp. 15-24
    • Chiarugi, A.1
  • 19
    • 2142694340 scopus 로고    scopus 로고
    • Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol
    • Hong, S.J.; Dawson, T.M.; Dawson, V.L. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling. Trends Pharmacol. Sci. 2004, 25, 259-264.
    • (2004) Sci , vol.25 , pp. 259-264
    • Hong, S.J.1    Dawson, T.M.2    Dawson, V.L.3
  • 20
    • 35448960851 scopus 로고    scopus 로고
    • Functions and dysfunctions of mitochondrial dynamics
    • Detmer, S.A.; Chan, D.C. Functions and dysfunctions of mitochondrial dynamics. Nat. Rev. Mol. Cell Biol. 2007, 8, 870-879.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 870-879
    • Detmer, S.A.1    Chan, D.C.2
  • 21
    • 77957358299 scopus 로고    scopus 로고
    • Mitochondrial dynamics in cell death and neurodegeneration
    • Cho, D.H.; Nakamura, T.; Lipton, S.A. Mitochondrial dynamics in cell death and neurodegeneration. Cell. Mol. Life Sci. 2010, 67, 3435-3447.
    • (2010) Cell. Mol. Life Sci , vol.67 , pp. 3435-3447
    • Cho, D.H.1    Nakamura, T.2    Lipton, S.A.3
  • 22
    • 79952443408 scopus 로고    scopus 로고
    • Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
    • Song, W.; Chen, J.; Petrilli, A.; Liot, G.; Klinglmayr, E.; Zhou, Y.; Poquiz, P.; Tjong, J.; Pouladi, M.A.; Hayden, M.R., et al. Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity. Nat. Med. 2011, 17, 377-382.
    • (2011) Nat. Med , vol.17 , pp. 377-382
    • Song, W.1    Chen, J.2    Petrilli, A.3    Liot, G.4    Klinglmayr, E.5    Zhou, Y.6    Poquiz, P.7    Tjong, J.8    Pouladi, M.A.9    Hayden, M.R.10
  • 23
    • 58049218922 scopus 로고    scopus 로고
    • Amyloid-b overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
    • Wang, X.; Su, B.; Siedlak, S.L.; Moreira, P.I.; Fujioka, H.; Wang, Y.; Casadesus, G.; Zhu, X. Amyloid-b overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. PNAS 2008, 105, 19318-19323.
    • (2008) PNAS , vol.105 , pp. 19318-19323
    • Wang, X.1    Su, B.2    Siedlak, S.L.3    Moreira, P.I.4    Fujioka, H.5    Wang, Y.6    Casadesus, G.7    Zhu, X.8
  • 24
    • 0036192440 scopus 로고    scopus 로고
    • Ultrastructural changes of neuronal mitochondria after transient and permanent cerebral ischemia
    • Solenski, N.J.; diPierro, C.G.; Trimmer, P.A.; Kwan, A.L.; Helms, G.A. Ultrastructural changes of neuronal mitochondria after transient and permanent cerebral ischemia. Stroke 2002, 33, 816-824.
    • (2002) Stroke , vol.33 , pp. 816-824
    • Solenski, N.J.1    Dipierro, C.G.2    Trimmer, P.A.3    Kwan, A.L.4    Helms, G.A.5
  • 25
    • 77956511129 scopus 로고    scopus 로고
    • Different pathways lead to mitochondrial fragmentation during apoptotic and excitotoxic cell death in primary neurons
    • Young, K.W.; Piñon, L.G.P.; Bampton, E.T.W.; Nicotera, P. Different pathways lead to mitochondrial fragmentation during apoptotic and excitotoxic cell death in primary neurons. J. Biochem. Mol. Toxicol. 2010, 24, 335-341.
    • (2010) J. Biochem. Mol. Toxicol , vol.24 , pp. 335-341
    • Young, K.W.1    Piñon, L.2    Bampton, E.3    Nicotera, P.4
  • 26
    • 79953019314 scopus 로고    scopus 로고
    • The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity
    • Jahani-Asl, A.; Pilon-Larose, K.; Xu, W.; MacLaurin, J.G.; Park, D.S.; McBride, H.M.; Slack, R.S. The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity. J. Biol. Chem. 2011, 286, 4772-4782.
    • (2011) J. Biol. Chem , vol.286 , pp. 4772-4782
    • Jahani-Asl, A.1    Pilon-Larose, K.2    Xu, W.3    Maclaurin, J.G.4    Park, D.S.5    McBride, H.M.6    Slack, R.S.7
  • 27
    • 79952369773 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production
    • Valerio, A.; Bertolotti, P.; Delbarba, A.; Perego, C.; Dossena, M.; Ragni, M.; Spano, P.; Carruba, M.O.; de Simoni, M.G.; Nisoli, E. Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production. J. Neurochem. 2011, 116, 1148-1159.
    • (2011) J. Neurochem , vol.116 , pp. 1148-1159
    • Valerio, A.1    Bertolotti, P.2    Delbarba, A.3    Perego, C.4    Dossena, M.5    Ragni, M.6    Spano, P.7    Carruba, M.O.8    De Simoni, M.G.9    Nisoli, E.10
  • 28
    • 0034798348 scopus 로고    scopus 로고
    • Reduction and Restoration of Mitochondrial DNA Content After Focal Cerebral Ischemia/Reperfusion
    • Chen, H.; Hu, C.J.; He, Y.Y.; Yang, D.I.; Xu, J.; Hsu, C.Y. Reduction and Restoration of Mitochondrial DNA Content After Focal Cerebral Ischemia/Reperfusion. Stroke 2001, 32, 2382-2387.
    • (2001) Stroke , vol.32 , pp. 2382-2387
    • Chen, H.1    Hu, C.J.2    He, Y.Y.3    Yang, D.I.4    Xu, J.5    Hsu, C.Y.6
  • 29
    • 84867516589 scopus 로고    scopus 로고
    • Mitochondrial biogenesis contributes to ischemic neuroprotection afforded by LPS pre-conditioning
    • Stetler, R.A.; Leak, R.K.; Yin, W.; Zhang, L.; Wang, S.; Gao, Y.; Chen, J. Mitochondrial biogenesis contributes to ischemic neuroprotection afforded by LPS pre-conditioning. J. Neurochem. 2012, 123 (Suppl. 2), 125-137.
    • (2012) J. Neurochem , vol.123 , pp. 125-137
    • Stetler, R.A.1    Leak, R.K.2    Yin, W.3    Zhang, L.4    Wang, S.5    Gao, Y.6    Chen, J.7
  • 30
    • 84891139900 scopus 로고    scopus 로고
    • NAD+ treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells
    • Hong, Y.; Nie, H.; Wu, D.; Wei, X.; Ding, X.; Ying, W. NAD+ treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells. Neurosci. Lett. 2014, 2014, 46-50.
    • (2014) Neurosci. Lett , vol.2014 , pp. 46-50
    • Hong, Y.1    Nie, H.2    Wu, D.3    Wei, X.4    Ding, X.5    Ying, W.6
  • 33
    • 0030832874 scopus 로고    scopus 로고
    • Ischemic brain injury is mediated by the activation of poly(ADP-Ribose)polymerase
    • Endres, M.; Wang, Z.Q.; Namura, S.; Waeber, C.; Moskowitz, M.A. Ischemic brain injury is mediated by the activation of poly(ADP-Ribose)polymerase. J. Cereb. Blood Flow Metab. 1997, 17, 1143-1151.
    • (1997) J. Cereb. Blood Flow Metab , vol.17 , pp. 1143-1151
    • Endres, M.1    Wang, Z.Q.2    Namura, S.3    Waeber, C.4    Moskowitz, M.A.5
  • 34
    • 77649133016 scopus 로고    scopus 로고
    • Swanson, R.A. NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death
    • Alano, C.C.; Garnier, P.; Ying, W.; Higashi, Y.; Kauppinen, T.M.; Swanson, R.A. NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. J. Neurosci. 2010, 30, 2967-2978.
    • (2010) J. Neurosci , vol.30 , pp. 2967-2978
    • Alano, C.C.1    Garnier, P.2    Ying, W.3    Higashi, Y.4    Kauppinen, T.M.5
  • 36
    • 33750358771 scopus 로고    scopus 로고
    • Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia
    • Niimura, M.; Takagi, N.; Takagi, K.; Mizutani, R.; Ishihara, N.; Matsumoto, K.; Funakoshi, H.; Nakamura, T.; Takeo, S. Prevention of apoptosis-inducing factor translocation is a possible mechanism for protective effects of hepatocyte growth factor against neuronal cell death in the hippocampus after transient forebrain ischemia. J. Cereb. Blood Flow Metab. 2006, 26, 1354-1365.
    • (2006) J. Cereb. Blood Flow Metab , vol.26 , pp. 1354-1365
    • Niimura, M.1    Takagi, N.2    Takagi, K.3    Mizutani, R.4    Ishihara, N.5    Matsumoto, K.6    Funakoshi, H.7    Nakamura, T.8    Takeo, S.9
  • 37
    • 26444580828 scopus 로고    scopus 로고
    • Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release
    • Zhang, Y.M.; Bhavnani, B.R. Glutamate-induced apoptosis in primary cortical neurons is inhibited by equine estrogens via down-regulation of caspase-3 and prevention of mitochondrial cytochrome c release. BMC Neurosci. 2005, 6, 13.
    • (2005) BMC Neurosci , vol.6 , pp. 13
    • Zhang, Y.M.1    Bhavnani, B.R.2
  • 38
    • 84890815650 scopus 로고    scopus 로고
    • Addition of exogenous NAD+ prevents mefloquine-induced neuroaxonal and hair cell degeneration through reduction of caspase-3-mediated apoptosis in cochlear organotypic cultures
    • Ding, D.; Qi, W.; Yu, D.; Jiang, H.; Han, C.; Kim, M.J.; Katsuno, K.; Hsieh, Y.H.; Miyakawa, T.; Salvi, R., et al. Addition of exogenous NAD+ prevents mefloquine-induced neuroaxonal and hair cell degeneration through reduction of caspase-3-mediated apoptosis in cochlear organotypic cultures. PLoS One 2013, 8, e79817.
    • (2013) Plos One , vol.8
    • Ding, D.1    Qi, W.2    Yu, D.3    Jiang, H.4    Han, C.5    Kim, M.J.6    Katsuno, K.7    Hsieh, Y.H.8    Miyakawa, T.9    Salvi, R.10
  • 39
    • 0041819756 scopus 로고    scopus 로고
    • Glutamate decreases mitochondrial size and movement in primary forebrain neurons
    • Rintoul, G.L.; Filiano, A.J.; Brocard, J.B.; Kress, G.J.; Reynolds, I.J. Glutamate decreases mitochondrial size and movement in primary forebrain neurons. J Neurosci. 2003, 23, 78881-78888.
    • (2003) J Neurosci , vol.23 , pp. 78881-78888
    • Rintoul, G.L.1    Filiano, A.J.2    Brocard, J.B.3    Kress, G.J.4    Reynolds, I.J.5
  • 40
    • 84898690811 scopus 로고    scopus 로고
    • Mitochondrial morphology is dynamic and varied
    • Rube, D.A.; van der Bliek, A.M. Mitochondrial morphology is dynamic and varied. Mol. Cell. Biochem. 2004, 2004, 256-257.
    • (2004) Mol. Cell. Biochem , vol.2004 , pp. 256-257
    • Rube, D.A.1    Van Der Bliek, A.M.2
  • 41
    • 79958721260 scopus 로고    scopus 로고
    • Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer’s disease: Implications for neuronal damage
    • Manczak, M.; Calkins, M.J.; Reddy, P.H. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer’s disease: Implications for neuronal damage. Hum. Mol. Genet. 2011, 20, 2495-2509.
    • (2011) Hum. Mol. Genet , vol.20 , pp. 2495-2509
    • Manczak, M.1    Calkins, M.J.2    Reddy, P.H.3
  • 42
    • 0037455575 scopus 로고    scopus 로고
    • Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
    • Chen, H.; Detmer, S.A.; Ewald, A.J.; Griffin, E.E.; Fraser, S.E.; Chan, D.C. Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J. Cell Biol. 2003, 160, 189-200.
    • (2003) J. Cell Biol , vol.160 , pp. 189-200
    • Chen, H.1    Detmer, S.A.2    Ewald, A.J.3    Griffin, E.E.4    Fraser, S.E.5    Chan, D.C.6
  • 45
    • 74149091370 scopus 로고    scopus 로고
    • NMDA receptor dependent PGC-1alpha up-regulation protects the cortical neuron against oxygen-glucose deprivation/reperfusion injury
    • Luo, Y.; Zhu, W.; Jia, J.; Zhang, C.; Xu, Y. NMDA receptor dependent PGC-1alpha up-regulation protects the cortical neuron against oxygen-glucose deprivation/reperfusion injury. J. Mol. Neurosci. 2009, 39, 262-268.
    • (2009) J. Mol. Neurosci , vol.39 , pp. 262-268
    • Luo, Y.1    Zhu, W.2    Jia, J.3    Zhang, C.4    Xu, Y.5
  • 47
    • 77953285783 scopus 로고    scopus 로고
    • Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α expression in experimental stroke
    • Zhu, H.R.; Wang, Z.Y.; Zhu, X.L.; Wu, X.X.; Li, E.G.; Xu, Y. Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α expression in experimental stroke. Neuropharmacology 2010, 59, 70-76.
    • (2010) Neuropharmacology , vol.59 , pp. 70-76
    • Zhu, H.R.1    Wang, Z.Y.2    Zhu, X.L.3    Wu, X.X.4    Li, E.G.5    Xu, Y.6
  • 49
    • 55749114205 scopus 로고    scopus 로고
    • Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury
    • Yin, W.; Signore, A.P.; Iwai, M.; Cao, G.; Gao, Y.; Chen, J. Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury. Stroke 2008, 39, 3057-3063.
    • (2008) Stroke , vol.39 , pp. 3057-3063
    • Yin, W.1    Signore, A.P.2    Iwai, M.3    Cao, G.4    Gao, Y.5    Chen, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.