NAD+ treatment prevents rotenone-induced apoptosis and necrosis of differentiated PC12 cells

Neuroscience Letters

Volumn 560, Issue , 2014, Pages 46-50

  Hong, Yunyi ^a   Nie, Hui ^a   Wu, Danhong ^b   Wei, Xunbin ^a   Ding, Xianting ^a   Ying, Weihai ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Apoptosis; Mitochondrial membrane potential; Necrosis; PC12 cells; Rotenone

Indexed keywords

LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE; ROTENONE;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL LEVEL; CELL MEMBRANE DEPOLARIZATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; FLOW CYTOMETRY; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROPROTECTION; PC12 CELL; PRIORITY JOURNAL;

APOPTOSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; NAD(+); NECROSIS; PC12 CELLS; ROTENONE;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; INSECTICIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; NAD; NECROSIS; PC12 CELLS; RATS; ROTENONE;

EID: 84891139900     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.11.039     Document Type: Article

References (25)

1. + depletion is necessary and sufficient for poly (ADP-ribose) polymerase-1-mediated neuronal death. J. Neurosci. 2010, 30:2967-2978.
2. + depletion and mitochondrial permeability transition. J. Biol. Chem. 2004, 279:18895-18902.
3. Baker C.A., Bousheri S., Ssewanyana I., Jones N.G., K'Aluoch O., Baliruno D., Ssali F., Huyen C. HIV subtypes distribution and implication for antiretroviral treatment in a Ugandan population. J. Int. Assoc. Physicians AIDS Care (Chic.) 2007, 6:260-263.
4. V. Borutaite, Mitochondria as decision-makers in cell death, Environ. Mol. Mutagen 51 406-416.
5. Greenamyre J.T., Betarbet R., Sherer T.B. The rotenone model of Parkinson's disease: genes, environment and mitochondria. Parkinsonism Relat. Disord. 2003, 9(Suppl. 2):S59-S64.
6. Greenamyre J.T., MacKenzie G., Peng T.I., Stephans S.E. Mitochondrial dysfunction in Parkinson's disease. Biochem. Soc. Symp. 1999, 66:85-97.
7. + treatment can block rotenone-induced nuclear apoptotic changes of PC12 cells. FASEB J. 2010, 24. (2010' Experimental Biology Meeting Abstracts) 965.6.
8. Kristal B.S., Stavrovskaya I.G., Narayanan M.V., Krasnikov B.F., Brown A.M., Beal M.F., Friedlander R.M. The mitochondrial permeability transition as a target for neuroprotection. J. Bioenerg. Biomembr. 2004, 36:309-312.
9. + oxidation-reduction state. Biochem. J. 2002, 368:545-553.
10. Lu C., Wang Y., Furukawa K., Fu W., Ouyang X., Mattson M.P. Evidence that caspase-1 is a negative regulator of AMPA receptor-mediated long-term potentiation at hippocampal synapses. J. Neurochem. 2006, 97:1104-1110.
11. Ly J.D., Grubb D.R., Lawen A. The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update. Apoptosis 2003, 8:115-128.
12. Ma Y., Jiang J., Wang L., Nie H., Xia W., Liu J., Ying W. CD38 is a key enzyme for the survival of mouse microglial BV2 cells. Biochem. Biophys. Res. Commun. 2012, 418:714-719.
13. Marella M., Seo B.B., Matsuno-Yagi A., Yagi T. Mechanism of cell death caused by complex I defects in a rat dopaminergic cell line. J. Biol. Chem. 2007, 282:24146-24156.
14. Norenberg M.D., Rao K.V. The mitochondrial permeability transition in neurologic disease. Neurochem. Int. 2007, 50:983-997.
15. Petit P.X., Goubern M., Diolez P., Susin S.A., Zamzami N., Kroemer G. Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition. FEBS Lett. 1998, 426:111-116.
16. Pittelli M., Felici R., Pitozzi V., Giovannelli L., Bigagli E., Cialdai F., Romano G., Moroni F., Chiarugi A. Pharmacological effects of exogenous NAD on mitochondrial bioenergetics, DNA repair, and apoptosis. Mol. Pharmacol. 2011, 80:1136-1146.
17. Polster B.M., Basanez G., Etxebarria A., Hardwick J.M., Nicholls D.G. Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J. Biol. Chem. 2005, 280:6447-6454.
18. Tsujimoto Y., Shimizu S. Role of the mitochondrial membrane permeability transition in cell death. Apoptosis 2007, 12:835-840.
19. Ying W. Deleterious network: a testable pathogenetic concept of Alzheimer's disease. Gerontology 1997, 43:242-253.
20. + and NADH in cellular functions and cell death. Front. Biosci. 2006, 11:3129-3148.
21. +/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid. Redox Signal. 2008, 10:179-206.
22. Ying W. A new hypothesis of neurodegenerative diseases: the deleterious network hypothesis. Med. Hypotheses 1996, 47:307-313.
23. + repletion prevents PARP-1-induced glycolytic blockade and cell death in cultured mouse astrocytes. Biochem. Biophys. Res. Commun. 2003, 308:809-813.
24. + profoundly decreases brain injury in a rat model of transient focal ischemia. Front. Biosci. 2007, 12:2728-2734.
25. + administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia. Neurosci. Lett. 2012, 512:67-71.