Peptide array on cellulose support—a screening tool to identify peptides with dipeptidyl-peptidase IV inhibitory activity within the sequence of α-lactalbumin

International Journal of Molecular Sciences

Volumn 15, Issue 11, 2014, Pages 20846-20858

  Lacroix, Isabelle M E ^a   Li Chan, Eunice C Y ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Dipeptidyl peptidase IV (DPP IV) inhibitors; Peptide array; Peptide DPP IV interaction; lactalbumin

Indexed keywords

ALPHA LACTALBUMIN; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; CELLULOSE; LACTALBUMIN; PEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; BIOINFORMATICS; CELLULOSE BOUND PEPTIDE ARRAY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME KINETICS; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN MICROARRAY; PROTEIN STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; SYNTHESIS;

AMINO ACID SEQUENCE; CELLULOSE; CHEMISTRY TECHNIQUES, SYNTHETIC; DIPEPTIDYL PEPTIDASE 4; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; DRUG DISCOVERY; HEK293 CELLS; HUMANS; LACTALBUMIN; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN ARRAY ANALYSIS;

EID: 84910110593     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms151120846     Document Type: Article

References (30)

1. Jahan-Mihan, A.; Luhovyy, B.L.; Khoury, D.E.; Anderson, G.H. Dietary proteins as determinants of metabolic and physiologic functions of the gastrointestinal tract. Nutrients 2011, 3, 574-603.
2. Shahidi, F.; Zhong, Y. Bioactive peptides. J. AOAC Int. 2008, 91, 914-931.
3. Korhonen, H. Milk-derived bioactive peptides: From science to applications. J. Funct. Foods 2009, 1, 177-187.
4. Hartmann, R.; Meisel, H. Food-derived peptides with biological activity: From research to food applications. Curr. Opin. Biotechnol. 2007, 18, 163-169.
5. Jauregi, P. Bioactive peptides from food proteins: New opportunities and challenges. Food Sci. Tech. Bull. Funct. Foods 2008, 5, 11-25.
6. Kamau, S.M.; Lu, R.-R.; Chen, W.; Liu, X.-M.; Tian, F.-W.; Shen, Y.; Gao, T. Functional significance of bioactive peptides derived from milk proteins. Food Rev. Int. 2010, 26, 386-401.
7. Dziuba, M.; Dziuba, B.; Iwaniak, A. Milk proteins as precursors of bioactive peptides. Acta Sci. Pol. Technol. Aliment. 2009, 8, 71-90.
8. Tulipano, G.; Sibilia, V.; Caroli, A.M.; Cocchi, D. Whey proteins as sources of dipeptidyl peptidase IV (dipeptidyl peptidase-4) inhibitors. Peptides 2011, 32, 835-838.
9. Uchida, M.; Ohshida, Y.; Mogami, O. Novel dipeptidyl peptidase-4-inhibiting peptide derived from β-lactoglobulin. J. Pharmacol. Sci. 2011, 117, 63-66.
10. Uenishi, H.; Kabuki, T.; Seto, Y.; Serizawa, A.; Nakajima, H. Isolation and identification of casein-derived dipeptidyl-peptidase 4 (DPP-4)-inhibitory peptide LPQNIPPL from gouda-type cheese and its effect on plasma glucose in rats. Int. Dairy J. 2012, 22, 24-30.
11. Nongonierma, A.B.; FitzGerald, R.J. Dipeptidyl peptidase IV inhibitory and antioxidative properties of milk protein-derived peptides and hydrolysates. Peptides 2013, 39, 157-163.
12. Lacroix, I.M.E.; Li-Chan, E.C.Y. Evaluation of the potential of dietary proteins as precursors of dipeptidyl peptidase (DPP)-IV inhibitors by an in silico approach. J. Funct. Foods 2012, 4, 403-422.
13. Lacroix, I.M.E.; Li-Chan, E.C.Y. Dipeptidyl peptidase-IV inhibitory activity of dairy protein hydrolysates. Int. Dairy J. 2012, 25, 97-102.
14. Lacroix, I.M.E.; Li-Chan, E.C.Y. Inhibition of dipeptidyl peptidase (DPP)-IV and α-glucosidase activities by pepsin-treated whey proteins. J. Agric. Food Chem. 2013, 61, 7500-7506.
15. Lacroix, I.M.E.; Li-Chan, E.C.Y. Isolation and characterization of peptides with dipeptidyl peptidase-IV inhibitory activity from pepsin-treated bovine whey proteins. Peptides 2014, 54, 39-48.
16. Lim, G.E.; Brubaker, P. Glucagon-like peptide 1 secretion by the L-cell. The view from within. Diabetes 2006, 55, S70-S77.
17. Phillips, L.K.; Prins, J.B. Update on incretin hormones. Ann. N. Y. Acad. Sci. 2011, 1243, E55-E77.
18. Deacon, C.F. Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review. Diabetes Obes. Metab. 2011, 13, 7-18.
19. Udenigwe, C.C. Bioinformatics approaches, prospects and challenges of food bioactive peptide research. Trends Food Sci. Technol. 2014, 36, 137-143.
20. Khaldi, N. Bioinformatics approaches for identifying new therapeutic bioactive peptides in food. Funct. Foods Health Dis. 2012, 2, 325-338.
21. Li-Chan, E.C.Y.; Hunag, S.-L.; Jao, C.-L.; Ho, K.-P.; Hsu, K.-C. Peptides derived from Atlantic salmon skin gelatin as dipeptidyl-peptidase IV inhibitors. J. Agric. Food Chem. 2012, 60, 973-978.
22. Huang, S.-L.; Joa, C.-L.; Ho, K.-P.; Hsu, K.-C. Dipeptidyl-peptidase IV inhibitory activity of peptides derived from tuna cooking juice hydrolysates. Peptides 2012, 35, 114-121.
23. Hatanaka, T.; Inoue, Y.; Arima, J.; Kumagai, Y.; Usuki, H.; Kawakami, K.; Kimura, M.; Mukaihara, T. Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran. Food Chem. 2012, 134, 797-802.
24. Hilpert, K.; Winkler, D.F.H.; Hancock, R.E.W. Peptide arrays on cellulose support: SPOT synthesis, a time and cost effective method for synthesis of large numbers of peptides in a parallel and addressable fashion. Nat. Protoc. 2007, 2, 1333-1349.
25. Volkmer, R.; Tapia, V.; Landgraf, C. Synthetic peptide arrays for investigating protein interaction domains. FEBS Lett. 2012, 586, 2780-2786.
26. Min, D.-H.; Mrksich, M. Peptide arrays: Towards routine implementation. Curr. Opin. Chem. Biol. 2004, 8, 554-558.
27. Kühn-Wache, K.; Bär, J.; Hoffmann, T.; Wolf, R.; Rahfeld, J.-U.; Demuth, H.-U. Selective inhibition of dipeptidyl peptidase 4 by targeting a substrate-specific secondary binding site. Biol. Chem. 2011, 392, 223-231.
28. Lan, V.T.T.; Ito, K.; Ito, S.; Kawarasaki, Y. Trp-Arg-Xaa tripeptides act as uncompetitive-type inhibitors of human dipeptidyl peptidase IV. Peptides 2014, 54, 166-170.
29. Katz, C.; Levy-Beladev, L.; Rotem-Bamberger, S.; Rito, T.; Rüdiger, S.G.D.; Friedler, A. Studying protein-protein interactions using peptide arrays. Chem. Soc. Rev. 2011, 40, 2131-2145.
30. Zhong, J.; Rao, X.; Rajagopalan, S. An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease. Atherosclerosis 2013, 226, 305-314.