Subcutaneous adipocytes promote melanoma cell growth by activating the Akt signaling pathway: Role of palmitic acid

Journal of Biological Chemistry

Volumn 289, Issue 44, 2014, Pages 30525-30537

  Kwan, Hiu Yee ^a   Fu, Xiuqiong ^a   Liu, Bin ^b   Chao, Xiaojuan ^a   Chan, Chi Leung ^a   Cao, Huihui ^a   Su, Tao ^a   Tse, Anfernee Kai Wing ^a   Fong, Wang Fun ^a   Yu, Zhi Ling ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL GROWTH; CELL PROLIFERATION; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; DERMATOLOGY; GROWTH KINETICS; MAMMALS; ONCOLOGY; PALMITIC ACID; SATURATED FATTY ACIDS; TUMORS;

ADIPOSE TISSUE; EXOGENOUS SOURCE; FLUORESCENT DYES; LIPID ACCUMULATIONS; MELANOMA CELLS; OVER-EXPRESSION; SIGNALING PATHWAYS; TUMORIGENESIS;

CELL SIGNALING;

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PALMITIC ACID; PD 98509; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; INGUINAL REGION; LIPID STORAGE; MALE; MELANOMA; MELANOMA CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; ANIMAL; C57BL MOUSE; CANCER TRANSPLANTATION; ENZYME ACTIVATION; EXPERIMENTAL MELANOMA; LIPID METABOLISM; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; SKIN TUMOR; TUMOR CELL LINE; TUMOR VOLUME; WHITE ADIPOCYTE;

ADIPOCYTES, WHITE; ANIMALS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COCULTURE TECHNIQUES; ENZYME ACTIVATION; LIPID METABOLISM; MALE; MELANOMA, EXPERIMENTAL; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PALMITIC ACID; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; SUBCUTANEOUS FAT; TUMOR BURDEN;

EID: 84910092046     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.593210     Document Type: Article

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