Adipocyte-released insulin-like growth factor-1 is regulated by glucose and fatty acids and controls breast cancer cell growth in vitro

Diabetologia

Volumn 55, Issue 10, 2012, Pages 2811-2822

  D'Esposito, V ^a   Passaretti, F ^a,b   Hammarstedt, A ^c   Liguoro, D ^a   Terracciano, D ^a   Molea, G ^a   Canta, L ^a   Miele, C ^a   Smith, U ^c   Beguinot, F ^a   Formisano, P ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Adipocytes; Breast cancer; IGF 1

Indexed keywords

FATTY ACID; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; GLUCOSE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; KERATINOCYTE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; OLEIC ACID; PALMITIC ACID; PLATELET DERIVED GROWTH FACTOR; RANTES; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADIPOCYTE; ADIPOSE TISSUE; ADULT; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN 3T3; CELL STRAIN MCF 7; CELL SURVIVAL; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; STEM CELL;

ADENOCARCINOMA; ADIPOCYTES; ADULT; AGED; BREAST NEOPLASMS; CELL COMMUNICATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CHEMOKINE CCL5; COCULTURE TECHNIQUES; FEMALE; GLUCOSE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-8; MCF-7 CELLS; MIDDLE AGED; OBESITY; OLEIC ACID; PALMITATES; SIGNAL TRANSDUCTION;

EID: 84866135453     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2629-7     Document Type: Article

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