High-fat diet-induced obesity increases lymphangiogenesis and lymph node metastasis in the B16F10 melanoma allograft model: Roles of adipocytes and M2-macrophages

International Journal of Cancer

Volumn 136, Issue 2, 2015, Pages 258-270

  Jung, Jae In ^a   Cho, Han Jin ^b   Jung, Yoo Jin ^a   Kwon, Seung Hae ^c   Her, Song ^c   Choi, Sun Shim ^d   Shin, Seung Ho ^d   Lee, Ki Won ^b,e   Park, Jung Han Yoon ^a,e  

^a Hallym University   (South Korea)

^b Seoul National University   (South Korea)

^c Korea Basic Science Institute (KBSI)   (South Korea)

^d Kangwon National University   (South Korea)

^e Seoul National University   (South Korea)

Author keywords

high fat diet; lymphangiogenesis; melanoma; obesity

Indexed keywords

CHEMOKINE RECEPTOR CCR7; COLONY STIMULATING FACTOR 1; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; SECONDARY LYMPHOID TISSUE CHEMOKINE; VASCULOTROPIN C; VASCULOTROPIN D; VASCULOTROPIN RECEPTOR 3; CHEMOKINE; CYTOKINE; LEPTIN; MC4R PROTEIN, MOUSE; MELANOCORTIN 4 RECEPTOR; MESSENGER RNA;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CCL19 GENE; CCL2 GENE; CCL21 GENE; CCR7 GENE; CELL FUNCTION; CELL INTERACTION; CELL MATURATION; CELL MIGRATION; CELL VACUOLE; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; LYMPH NODE METASTASIS; LYMPHANGIOGENESIS; LYMPHATIC ENDOTHELIAL CELL; M CSF GENE; MACROPHAGE; MALE; MELANOMA; MELANOMA CELL; MONOCYTE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; UPREGULATION; VEGF C GENE; VEGF D GENE; VEGFR 3 GENE; ALLOGRAFT; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL MELANOMA; FLOW CYTOMETRY; GENETICS; KNOCKOUT MOUSE; LIPID DIET; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN MICROARRAY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE; TUMOR MICROENVIRONMENT; WESTERN BLOTTING;

ADIPOCYTES; ALLOGRAFTS; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CHEMOKINES; CYTOKINES; DIET, HIGH-FAT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; LEPTIN; LYMPHANGIOGENESIS; LYMPHATIC METASTASIS; MACROPHAGES; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PATHOLOGIC; OBESITY; PROTEIN ARRAY ANALYSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, MELANOCORTIN, TYPE 4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 84922286407     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28983     Document Type: Article

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