Lithium reduces the effects of rotenone-induced complex i dysfunction on DNA methylation and hydroxymethylation in rat cortical primary neurons

Psychopharmacology

Volumn 231, Issue 21, 2014, Pages 4189-4198

  Scola, Gustavo ^a,c,d   Kim, Helena K ^b,c   Young, L Trevor ^a,b,c   Salvador, Mirian ^d   Andreazza, Ana C ^a,b,c  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^d UNIVERSITY OF CAXIAS DO SUL   (Brazil)

Author keywords

Bipolar disorder; Complex I; Hydroxymethylation; Lithium; Methylation

Indexed keywords

5 METHYLCYTOSINE; ADENOSINE TRIPHOSPHATE; LITHIUM; NEUROLEPTIC AGENT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE;

ANIMAL; APOPTOSIS; BIPOLAR DISORDER; BRAIN CORTEX; CELL SURVIVAL; DNA METHYLATION; DRUG EFFECTS; METABOLISM; MITOCHONDRION; NERVE CELL; RAT;

5-METHYLCYTOSINE; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIPSYCHOTIC AGENTS; APOPTOSIS; BIPOLAR DISORDER; CELL SURVIVAL; CEREBRAL CORTEX; DNA METHYLATION; ELECTRON TRANSPORT COMPLEX I; LITHIUM; MITOCHONDRIA; NEURONS; RATS; ROTENONE;

EID: 84909609488     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-014-3565-7     Document Type: Article

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