메뉴 건너뛰기




Volumn 37, Issue 7, 2012, Pages 1647-1655

Selective DNA methylation of BDNF promoter in bipolar disorder: Differences among patients with BDI and BDII

Author keywords

bipolar disorder (BD); brain derived neurotrophic factor (BDNF); DNA methylation; Gene expression; mood stabilizers and antidepressants; peripheral blood mononuclear cells (PBMCs)

Indexed keywords

ANTIDEPRESSANT AGENT; ARIPIPRAZOLE; BRAIN DERIVED NEUROTROPHIC FACTOR; CITALOPRAM; CLOMIPRAMINE; DNA; DULOXETINE; ESCITALOPRAM; GABAPENTIN; LITHIUM; MOOD STABILIZER; OLANZAPINE; PREGABALIN; QUETIAPINE; SERTRALINE; VALPROIC ACID; VENLAFAXINE;

EID: 84861190781     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.10     Document Type: Article
Times cited : (151)

References (73)
  • 2
    • 22244471085 scopus 로고    scopus 로고
    • Genetics and epigenetics in major psychiatric disorders: Dilemmas, achievements, applications, and future scope
    • DOI 10.2165/00129785-200505030-00002
    • Abdolmaleky HM, Thiagalingam S, Wilcox M (2005). Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope. Am J Pharmacogenomics 5: 149-160. (Pubitemid 40994274)
    • (2005) American Journal of PharmacoGenomics , vol.5 , Issue.3 , pp. 149-160
    • Abdolmaleky, H.M.1    Thiagalingam, S.2    Wilcox, M.3
  • 3
    • 77954547258 scopus 로고    scopus 로고
    • Adenosine A2A receptor expression in peripheral blood mononuclear cells of patients with mild cognitive impairment
    • Arosio B, Viazzoli C, Mastronardi L, Bilotta C, Vergani C, Bergamaschini L (2010). Adenosine A2A receptor expression in peripheral blood mononuclear cells of patients with mild cognitive impairment. J Alzheimers Dis 20: 991-996.
    • (2010) J Alzheimers Dis , vol.20 , pp. 991-996
    • Arosio, B.1    Viazzoli, C.2    Mastronardi, L.3    Bilotta, C.4    Vergani, C.5    Bergamaschini, L.6
  • 4
    • 55549139122 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: Implications for the role of neuroplasticity in depression
    • Brunoni AR, Lopes M, Fregni F (2008). A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 11: 1169-1180.
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 1169-1180
    • Brunoni, A.R.1    Lopes, M.2    Fregni, F.3
  • 7
    • 77949746666 scopus 로고    scopus 로고
    • The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity
    • Castrén E, Rantamäki T (2010). The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity. Dev Neurobiol 70: 289-297.
    • (2010) Dev Neurobiol , vol.70 , pp. 289-297
    • Castrén, E.1    Rantamäki, T.2
  • 8
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • DOI 10.1016/S0006-3223(01)01083-6, PII S0006322301010836
    • Chen B, Dowlatshahi D, MacQueen GM, Wang JF, Young LT (2001). Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 50: 260-265. (Pubitemid 32778442)
    • (2001) Biological Psychiatry , vol.50 , Issue.4 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3    Wang, J.-F.4    Young L.Trevor5
  • 9
    • 71349083042 scopus 로고    scopus 로고
    • Decreased levels of serum brain-derived neurotrophic factor in drug-na?̈ve first-episode schizophrenia: Relationship to clinical phenotypes
    • Chen da C, Wang J, Wang B, Yang SC, Zhang CX, Zheng YL et al (2009). Decreased levels of serum brain-derived neurotrophic factor in drug-na?̈ve first-episode schizophrenia: relationship to clinical phenotypes. Psychopharmacology (Berl) 07: 375-380.
    • (2009) Psychopharmacology (Berl) , vol.7 , pp. 375-380
    • Chen Da, C.1    Wang, J.2    Wang, B.3    Yang, S.C.4    Zhang, C.X.5    Zheng, Y.L.6
  • 10
    • 34248663955 scopus 로고    scopus 로고
    • The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: Twenty-something years on
    • Chomczynski P, Sacchi N (2006). The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on. Nat Protoc 1: 581-585.
    • (2006) Nat Protoc , vol.1 , pp. 581-585
    • Chomczynski, P.1    Sacchi, N.2
  • 11
    • 13344260679 scopus 로고    scopus 로고
    • Lithium protection from glutamate excitotoxicity: Therapeutic implications
    • DOI 10.1016/j.cnr.2004.09.016, PII S1566277204000775
    • Chuang D-M (2004). Lithium protection from glutamate excitotoxicity: therapeutic implications. ClinNeurosci Res 4: 243-252. (Pubitemid 40197847)
    • (2004) Clinical Neuroscience Research , vol.4 , pp. 243-252
    • Chuang, D.-M.1
  • 12
    • 0037688084 scopus 로고    scopus 로고
    • Finding the intracellular signaling pathways affected by mood disorder treatments
    • DOI 10.1016/S0896-6273(03)00195-8
    • Coyle JT, Duman RS (2003). Finding the intracellular signaling pathways affected by mood disorder treatments. Neuron 38: 157-160. (Pubitemid 36555643)
    • (2003) Neuron , vol.38 , Issue.2 , pp. 157-160
    • Coyle, J.T.1    Duman, R.S.2
  • 13
    • 0034987584 scopus 로고    scopus 로고
    • Molecular genetics of bipolar disorder
    • Craddock N, Jones I (2001). Molecular genetics of bipolar disorder. Br J Psychiatry 178: 128-133. (Pubitemid 32530340)
    • (2001) British Journal of Psychiatry , vol.178 , Issue.SUPPL. 141 , pp. 128-133
    • Craddock, N.1    Jones, I.2
  • 15
    • 51649127761 scopus 로고    scopus 로고
    • Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
    • Dong E, Nelson M, Grayson DR, Costa E, Guidotti A (2008). Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation. Proc Natl Acad Sci USA 105: 13614-13619.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13614-13619
    • Dong, E.1    Nelson, M.2    Grayson, D.R.3    Costa, E.4    Guidotti, A.5
  • 16
    • 0042154427 scopus 로고    scopus 로고
    • Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects
    • DOI 10.1001/archpsyc.60.8.804
    • Dwivedi Y, Rizavi HS, Conley RR, Roberts RC, Tamminga CA, Pandey GN (2003). Altered gene expression of brain-derived neurotrophic factor and receptor tyrosine kinase B in postmortem brain of suicide subjects. Arch Gen Psychiatry 60: 804-815. (Pubitemid 36960912)
    • (2003) Archives of General Psychiatry , vol.60 , Issue.8 , pp. 804-815
    • Dwivedi, Y.1    Rizavi, H.S.2    Conley, R.R.3    Roberts, R.C.4    Tamminga, C.A.5    Pandey, G.N.6
  • 18
    • 34247469843 scopus 로고    scopus 로고
    • Epigenetic regulation of neural gene expression and neuronal function
    • DOI 10.1203/pdr.0b013e3180457635
    • Feng J, Fouse S, Fan G (2007). Epigenetic regulation of neural gene expression and neuronal function. Pediatr Res 2007 61(5 Pt 2): 58R-63R. . (Pubitemid 46653070)
    • (2007) Pediatric Research , vol.61 , Issue.5 PART 2
    • Feng, J.1    Fouse, S.2    Fan, G.3
  • 22
    • 80052287594 scopus 로고    scopus 로고
    • DNA methylation profiles of the brainderived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression
    • Fuchikami M, Morinobu S, Segawa M, Okamoto Y, Yamawaki S, Ozaki N et al (2011). DNA methylation profiles of the brainderived neurotrophic factor (BDNF) gene as a potent diagnostic biomarker in major depression. PLoS One 6: e23881.
    • (2011) PLoS One , vol.6
    • Fuchikami, M.1    Morinobu, S.2    Segawa, M.3    Okamoto, Y.4    Yamawaki, S.5    Ozaki, N.6
  • 23
    • 0033988813 scopus 로고    scopus 로고
    • DNA methyltransferase Dnmt1 associates with histone deacetylase activity
    • DOI 10.1038/71750
    • Fuks F, Burgers WA, Brehm A, Hughes-Davies L, Kouzarides T (2000). DNA methyl transferase Dnmt1 associates with histone deacetylase activity. Nat Genet 24: 88-91. (Pubitemid 30041428)
    • (2000) Nature Genetics , vol.24 , Issue.1 , pp. 88-91
    • Fuks, F.1    Burgers, W.A.2    Brehm, A.3    Hughes-Davies, L.4    Kouzarides, T.5
  • 24
    • 0037423186 scopus 로고    scopus 로고
    • The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
    • DOI 10.1074/jbc.M210256200
    • Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T (2003). The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem 278: 4035-4040. (Pubitemid 36801137)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.6 , pp. 4035-4040
    • Fuks, F.1    Hurd, P.J.2    Wolf, D.3    Nan, X.4    Bird, A.P.5    Kouzarides, T.6
  • 25
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain derived neurotrophic factor in the rat brain
    • Fukumoto T, Morinobu S, Okamoto Y, Kagaya A, Yamawaki S (2001). Chronic lithium treatment increases the expression of brain derived neurotrophic factor in the rat brain. Psychopharmacology (Berl) 158: 100-106.
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 26
    • 33750530675 scopus 로고    scopus 로고
    • Phase 1/2 study of the combination of 5-aza-20-deoxycytidine with valproic acid in patients with leukemia
    • Garcia-Manero G, Kantarjian HM, Sanchez-Gonzalez B, Yang H, Rosner G, Verstovsek S et al (2006). Phase 1/2 study of the combination of 5-aza-20-deoxycytidine with valproic acid in patients with leukemia. Blood 108: 3271-3279.
    • (2006) Blood , vol.108 , pp. 3271-3279
    • Garcia-Manero, G.1    Kantarjian, H.M.2    Sanchez-Gonzalez, B.3    Yang, H.4    Rosner, G.5    Verstovsek, S.6
  • 27
    • 77950627166 scopus 로고    scopus 로고
    • Histone modifications, DNA methylation, and schizophrenia
    • Gavin DP, Sharma RP (2010). Histone modifications, DNA methylation, and schizophrenia. Neurosci Biobehav Rev 34: 882-888.
    • (2010) Neurosci Biobehav Rev , vol.34 , pp. 882-888
    • Gavin, D.P.1    Sharma, R.P.2
  • 28
    • 4444322215 scopus 로고    scopus 로고
    • Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype
    • DOI 10.1176/appi.ajp.161.9.1698
    • Geller B, Badner JA, Tillman R (2004). Linkage disequilibrium of the brain derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype. Am J Psychiatry 161: 1698-1700. (Pubitemid 39201469)
    • (2004) American Journal of Psychiatry , vol.161 , Issue.9 , pp. 1698-1700
    • Geller, B.1    Badner, J.A.2    Tillman, R.3    Christian, S.L.4    Bolhofner, K.5    Cook Jr., E.H.6
  • 29
    • 0033968007 scopus 로고    scopus 로고
    • Bipolar illness and schizophrenia as oligogenic diseases: Implications for the future
    • DOI 10.1016/S0006-3223(99)00299-1, PII S0006322399002991
    • Gershon ES (2000). Bipolar illness and schizophrenia as oligogenic diseases: implications for the future. Biol Psychiatry 47: 240-244. (Pubitemid 30077400)
    • (2000) Biological Psychiatry , vol.47 , Issue.3 , pp. 240-244
    • Gershon, E.S.1
  • 30
    • 0348077406 scopus 로고    scopus 로고
    • Antidepressants in bipolar disorder: The case for caution
    • DOI 10.1046/j.1399-5618.2003.00074.x
    • Ghaemi SN, Hsu DJ, Soldani F, Goodwin FK (2003). Antidepressants in bipolar disorder: the case for caution. Bipolar Disord 5: 421-433. (Pubitemid 38072244)
    • (2003) Bipolar Disorders , vol.5 , Issue.6 , pp. 421-433
    • Nassir Ghaemi, S.1    Hsu, D.J.2    Soldani, F.3    Goodwin, F.K.4
  • 31
    • 79551638797 scopus 로고    scopus 로고
    • The role of BDNF as a mediator of neuroplasticity in bipolar disorder
    • Grande I, Fries GR, Kunz M, Kapczinski F (2010). The role of BDNF as a mediator of neuroplasticity in bipolar disorder. Psychiatry Investig 7: 243-250.
    • (2010) Psychiatry Investig , vol.7 , pp. 243-250
    • Grande, I.1    Fries, G.R.2    Kunz, M.3    Kapczinski, F.4
  • 33
    • 77649207564 scopus 로고    scopus 로고
    • The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression
    • Grunze H, Vieta E, Goodwin GM, Bowden C, Licht RW, Möller HJ et al (2010). The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression. World J Biol Psychiatry 11: 81-109.
    • (2010) World J Biol Psychiatry , vol.11 , pp. 81-109
    • Grunze, H.1    Vieta, E.2    Goodwin, G.M.3    Bowden, C.4    Licht, R.W.5    Möller, H.J.6
  • 35
    • 3242788185 scopus 로고    scopus 로고
    • Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis
    • DOI 10.1523/JNEUROSCI.5747-03.2004
    • Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P et al (2004). Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. J Neurosci 24: 6590-6599. (Pubitemid 38971708)
    • (2004) Journal of Neuroscience , vol.24 , Issue.29 , pp. 6590-6599
    • Hao, Y.1    Creson, T.2    Zhang, L.3    Li, P.4    Du, F.5    Yuan, P.6    Gould, T.D.7    Manji, H.K.8    Chen, G.9
  • 36
    • 2442597374 scopus 로고    scopus 로고
    • Critical role of brain-derived neurotrophic factor in mood disorders
    • DOI 10.1016/j.brainresrev.2004.02.003, PII S0165017304000189
    • Hashimoto K, Shimizu E, Iyo M (2004). Critical role of brainderived neurotrophic factor in mood disorders. Brain Res Rev 45: 104-114. (Pubitemid 38625738)
    • (2004) Brain Research Reviews , vol.45 , Issue.2 , pp. 104-114
    • Hashimoto, K.1    Shimizu, E.2    Iyo, M.3
  • 37
    • 0031201685 scopus 로고    scopus 로고
    • Exploring and explaining epigenetic effects
    • Henikoff S, Matzke MA (1997). Exploring and explaining epigenetic effects. Trends Genet 13: 293-295.
    • (1997) Trends Genet , vol.13 , pp. 293-295
    • Henikoff, S.1    Metzke, M.A.2
  • 38
    • 33646492288 scopus 로고    scopus 로고
    • Gene expression and association analysis of LIM (PDLIM5) in major depression
    • Iga J, Ueno S, Yamauchi K, Numata S, Motoki I, Tayoshi S et al (2006). Gene expression and association analysis of LIM (PDLIM5) in major depression. Neurosci Lett 400: 203-207.
    • (2006) Neurosci Lett , vol.400 , pp. 203-207
    • Iga, J.1    Ueno, S.2    Yamauchi, K.3    Numata, S.4    Motoki, I.5    Tayoshi, S.6
  • 39
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • DOI 10.1038/nrg2045, PII NRG2045
    • Jirtle RL, Skinner MK (2007). Environmental epigenomics and disease susceptibility. Nat Rev Genet 8: 253-262. (Pubitemid 46439287)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.4 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 41
    • 18944406852 scopus 로고    scopus 로고
    • Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs
    • DOI 10.1016/j.molbrainres.2004.12.020, PII S0169328X04006345
    • Karege F, Vaudan G, Schwald M, Perroud N, La Harpe R (2005). Neurotrophin levels in postmortem brains of suicide victims and the effects of antemortem diagnosis and psychotropic drugs. Brain Res Mol Brain Res 136: 29-37. (Pubitemid 40704606)
    • (2005) Molecular Brain Research , vol.136 , Issue.1-2 , pp. 29-37
    • Karege, F.1    Vaudan, G.2    Schwald, M.3    Perroud, N.4    La Harpe, R.5
  • 43
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • DOI 10.1016/j.tibs.2005.12.008, PII S096800040500352X
    • Klose RJ, Bird RP (2006). Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 31: 89-97. (Pubitemid 43221841)
    • (2006) Trends in Biochemical Sciences , vol.31 , Issue.2 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 45
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001). Analysis of relative gene expression data using real-time quantitative PCR and the 2(- Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 46
    • 42649117164 scopus 로고    scopus 로고
    • Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors
    • Lu X, Freund JN, Muller M, Ravey J, Nicolas JP, Gueant JL et al (2008). Differential regulation of CDX1 and CDX2 gene expression by deficiency in methyl group donors. Biochimie 90: 697-704.
    • (2008) Biochimie , vol.90 , pp. 697-704
    • Lu, X.1    Freund, J.N.2    Muller, M.3    Ravey, J.4    Nicolas, J.P.5    Gueant, J.L.6
  • 47
    • 0035559697 scopus 로고    scopus 로고
    • Mutation detection using fluorescent hybridization probes and melting curve analysis
    • Lyon E (2001). Mutation detection using fluorescent hybridization probes and melting curve analysis. Expert Rev Mol Diagn 1: 92-101. (Pubitemid 34654451)
    • (2001) Expert Review of Molecular Diagnostics , vol.1 , Issue.1 , pp. 92-101
    • Lyon, E.1
  • 48
    • 0242300612 scopus 로고    scopus 로고
    • DNA methylation-related chromatin remodeling in activitydependent BDNF gene regulation
    • DOI 10.1126/science.1090842
    • Martinowich K, Hattori D, Wu H, Fouse S, He F, Hu Y et al (2003). DNA methylation-related chromatin remodeling in activitydependent BDNF gene regulation. Science 302: 890-893. (Pubitemid 37339633)
    • (2003) Science , vol.302 , Issue.5646 , pp. 890-893
    • Martinowich, K.1    Hattori, D.2    Wu, H.3    Fouse, S.4    He, F.5    Hu, Y.6    Fan, G.7    Sun, Y.E.8
  • 49
    • 0003679737 scopus 로고
    • National Institute of Mental Health, Intramural Research Program, Clinical Neurogenetics Branch: Washington
    • Maxwell ME (1992). The Family Interview for Genetic Studies Manual. National Institute of Mental Health, Intramural Research Program, Clinical Neurogenetics Branch: Washington. .
    • (1992) The Family Interview for Genetic Studies Manual
    • Maxwell, M.E.1
  • 50
    • 84870892855 scopus 로고    scopus 로고
    • The relevance of epigenetics to major psychosis
    • Mill J, Petronis A (2009). The relevance of epigenetics to major psychosis. Epigenomics (Part IV): 411-434.
    • (2009) Epigenomics , Issue.PART IV , pp. 411-434
    • Mill, J.1    Petronis, A.2
  • 52
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, Asberg M (1979). A new depression scale designed to be sensitive to change. Br J Psychiatry 134: 382-389. (Pubitemid 9136500)
    • (1979) British Journal of Psychiatry , vol.134 , Issue.4 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 54
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • DOI 10.1038/30764
    • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN et al (1998). Transcriptional repression by the methyl-CpGbinding protein MeCP2 involves a histone deacetylase complex. Nature 393: 386-389. (Pubitemid 28269714)
    • (1998) Nature , vol.393 , Issue.6683 , pp. 386-389
    • Nan, X.1    Ng, H.-H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 55
    • 59449106949 scopus 로고    scopus 로고
    • Methylation-sensitive linking libraries enhance gene-enriched sequencing of complex genomes and map DNA methylation domains
    • Nelson W, Luo M, Ma J, Estep M, Estill J, He R et al (2008). Methylation-sensitive linking libraries enhance gene-enriched sequencing of complex genomes and map DNA methylation domains. BMC Genomics 9: 621.
    • (2008) BMC Genomics , vol.9 , pp. 621
    • Nelson, W.1    Luo, M.2    Ma, J.3    Estep, M.4    Estill, J.5    He, R.6
  • 56
    • 0036724341 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: Evidence from a family-based association study
    • DOI 10.1086/342288
    • Neves-Perreira M, Mundo E, Muglia P (2002). The brain derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family based association study. Am J Hum Genet 71: 651-655. (Pubitemid 34970137)
    • (2002) American Journal of Human Genetics , vol.71 , Issue.3 , pp. 651-655
    • Neves-Pereira, M.1    Mundo, E.2    Muglia, P.3    King, N.4    Macciardi, F.5    Kennedy, J.L.6
  • 57
    • 0028815653 scopus 로고
    • Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
    • Nibuya M, Morinobu S, Duman RS (1995). Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 15: 7539-7547.
    • (1995) J Neurosci , vol.15 , pp. 7539-7547
    • Nibuya, M.1    Morinobu, S.2    Duman, R.S.3
  • 58
    • 55749111396 scopus 로고    scopus 로고
    • Brainderived neurotrophic factor gene expression in pediatric bipolar disorder: Effects of treatment and clinical response
    • Pandey GN, Rizavi HS, Dwivedi Y, Pavuluri MN (2008). Brainderived neurotrophic factor gene expression in pediatric bipolar disorder: effects of treatment and clinical response. J Am Acad Child Adolesc Psychiatry 47: 1077-1085.
    • (2008) J Am Acad Child Adolesc Psychiatry , vol.47 , pp. 1077-1085
    • Pandey, G.N.1    Rizavi, H.S.2    Dwivedi, Y.3    Pavuluri, M.N.4
  • 60
    • 78650429158 scopus 로고    scopus 로고
    • Epigenetic studies of psychosis: Current findings, methodological approaches and implications for postmortem research
    • Pidsley R, Mill J (2011). Epigenetic studies of psychosis: current findings, methodological approaches and implications for postmortem research. Biol Psychiatry 69: 146-156.
    • (2011) Biol Psychiatry , vol.69 , pp. 146-156
    • Pidsley, R.1    Mill, J.2
  • 61
    • 65749119032 scopus 로고    scopus 로고
    • Reduced serum BDNF levels in patients with chronic schizophrenic disorder in relapse, who were treated with typical or atypical antipsychotics
    • Rizos EN, Papadopoulou A, Laskos E, Michalopoulou PG, Kastania A, Vasilopoulos D et al (2008). Reduced serum BDNF levels in patients with chronic schizophrenic disorder in relapse, who were treated with typical or atypical antipsychotics. World J Biol Psychiatry 10: 1-5.
    • (2008) World J Biol Psychiatry , vol.10 , pp. 1-5
    • Rizos, E.N.1    Papadopoulou, A.2    Laskos, E.3    Michalopoulou, P.G.4    Kastania, A.5    Vasilopoulos, D.6
  • 62
    • 0036024263 scopus 로고    scopus 로고
    • Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus
    • Roceri M, Hendriks W, Racagni G, Ellenbroek BA, Riva MA (2002). Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus. Mol Psychiatry 7: 609-616.
    • (2002) Mol Psychiatry , vol.7 , pp. 609-616
    • Roceri, M.1    Hendriks, W.2    Racagni, G.3    Ellenbroek, B.A.4    Riva, M.A.5
  • 63
    • 0032863708 scopus 로고    scopus 로고
    • Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression
    • DOI 10.1016/S0893-133X(99)00059-7, PII S0893133X99000597
    • Russo-Neustadt A, Beard RC, Cotman CW (1999). Exercise, antidepressant medications, and enhanced brain derived neurotrophic factor expression. Neuropsychopharmacology 21: 679-682. (Pubitemid 29486636)
    • (1999) Neuropsychopharmacology , vol.21 , Issue.5 , pp. 679-682
    • Russo-Neustadt, A.1    Beard, R.C.2    Cotman, C.W.3
  • 65
    • 49749101642 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor, depression, and antidepressant medications: Meta-analyses and implications
    • Sen S, Duman R, Sanacora G (2008). Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry 64: 527-532.
    • (2008) Biol Psychiatry , vol.64 , pp. 527-532
    • Sen, S.1    Duman, R.2    Sanacora, G.3
  • 66
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS (2002). Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 22: 3251-3261. (Pubitemid 35379212)
    • (2002) Journal of Neuroscience , vol.22 , Issue.8 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.-H.2    Nakagawa, S.3    Russell, D.S.4    Duman, R.S.5
  • 67
    • 0036347948 scopus 로고    scopus 로고
    • Family based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus
    • Sklar P, Gabriel SB, McInnis MG (2002). Family based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Mol Psychiatry 7: 579-593.
    • (2002) Mol Psychiatry , vol.7 , pp. 579-593
    • Sklar, P.1    Gabriel, S.B.2    McInnis, M.G.3
  • 69
    • 0027402152 scopus 로고
    • Multiple promoters direct tissue-specific expression of the rat BDNF gene
    • Timmuskb T (1993). Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron 10: 475-489.
    • (1993) Neuron , vol.10 , pp. 475-489
    • Timmuskb, T.1
  • 70
    • 73549085850 scopus 로고    scopus 로고
    • DNA methylation: An introduction to the biology and the disease-associated changes of a promising biomarker
    • Tost J (2010). DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker. Mol Biotechnol 44: 71-81.
    • (2010) Mol Biotechnol , vol.44 , pp. 71-81
    • Tost, J.1
  • 72
    • 34848841583 scopus 로고    scopus 로고
    • Robust stimulation of TrkB induces delayed increases in BDNF and Arc mRNA expressions in cultured rat cortical neurons via distinct mechanisms
    • DOI 10.1111/j.1471-4159.2007.04851.x
    • Yasuda M, Fukuchi M, Tabuchi A, Kawahara M, Tsuneki H, Azuma Y et al (2007). Robust stimulation of TrkB induces delayed increases in BDNF and Arc mRNA expressions in cultured rat cortical neurons via distinct mechanisms. J Neurochem 103: 626-636. (Pubitemid 47498045)
    • (2007) Journal of Neurochemistry , vol.103 , Issue.2 , pp. 626-636
    • Yasuda, M.1    Fukuchi, M.2    Tabuchi, A.3    Kawahara, M.4    Tsuneki, H.5    Azuma, Y.6    Chiba, Y.7    Tsuda, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.