The effect of mood stabilizer lithium on expression and activity of glutathione s-transferase isoenzymes

Neuroscience

Volumn 151, Issue 2, 2008, Pages 518-524

  Shao, L ^a   Cui, J ^a   Young, L T ^a   Wang, J F ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

bipolar disorder; cell death; cerebral cortical cells; DNA fragmentation; mood stabilizing drug; oxidative stress

Indexed keywords

DNA FRAGMENT; ETACRYNIC ACID; GLUTATHIONE; GLUTATHIONE S TRANSFERASE MU5; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A4; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE M3; HYDROGEN PEROXIDE; LITHIUM; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIPOLAR DISORDER; BRAIN CELL; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; DRUG EFFECT; ENZYME ACTIVITY; FETUS; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIMANIC AGENTS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; DIURETICS; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHACRYNIC ACID; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; IN SITU NICK-END LABELING; ISOENZYMES; LITHIUM CHLORIDE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 37849054293     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.10.041     Document Type: Article

References (33)

1. Bachmann R.F., Schloesser R.J., Gould T.D., and Manji H.K. Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics. Mol Neurobiol 32 (2005) 173-202
2. Bowden C.L. Treatment of bipolar disorder. In: Schatzberg A.F., and Nemeroff C.B. (Eds). Textbook of psychopharmacology (1995), APA Press, Washington, DC 603-614
3. Chen R.W., Qin Z.H., Ren M., Kanai H., Chalecka-Franaszek E., Leeds P., and Chuang D.M. Regulation of c-Jun N-terminal kinase, p38 kinase and AP-1 DNA binding in cultured brain neurons: roles in glutamate excitotoxicity and lithium neuroprotection. J Neurochem 84 (2003) 566-575
4. Cho S.G., Lee Y.H., Park H.S., Ryoo K., Kang K.W., Park J., Eom S.J., Kim M.J., Chang T.S., Choi S.Y., Shim J., Kim Y., Dong M.S., Lee M.J., Kim S.G., Ichijo H., and Choi E.J. Glutathione s-transferase mu modulates the stress-activated signals by suppressing apoptosis signal-regulating kinase 1. J Biol Chem 276 (2001) 12749-12755
5. Chuang D.M. The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials. Ann N Y Acad Sci 1053 (2005) 195-204
6. Cui J., Shao L., Young L.T., and Wang J.F. Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate. Neuroscience 144 (2007) 1447-1453
7. Dager S.R., Friedman S.D., Parow A., Demopulos C., Stoll A.L., Lyoo I.K., Dunner D.L., and Renshaw P.F. Brain metabolic alterations in medication-free patients with bipolar disorder. Arch Gen Psychiatry 61 (2004) 450-458
8. Deicken R.F., Fein G., and Weiner M.W. Abnormal frontal lobe phosphorous metabolism in bipolar disorder. Am J Psychiatry 152 (1995) 915-918
9. Eaton D.L., and Bammler T.K. Concise review of the glutathione S-transferases and their significance to toxicology. Toxicol Sci 49 (1999) 156-164
10. Frey B.N., Valvassori S.S., Réus G.Z., Martins M.R., Petronilho F.C., Bardini K., Dal-Pizzol F., Kapczinski F., and Quevedo J. Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania. J Psychiatry Neurosci 31 (2006) 326-332
11. Gelenberg A.J., Kane J.M., Keller M.B., Lavori P., Rosenbaum J.F., Cole K., and Lavelle J. Comparison of standard and low serum levels of lithium for maintenance treatment of bipolar disorder. N Engl J Med 321 (1989) 1489-1493
12. Ghribi O., Prammonjago P., Herman M.M., Spaulding N.K., and Savory J. Abeta(1-42)-induced JNK and ERK activation in rabbit hippocampus is differentially regulated by lithium but is not involved in the phosphorylation of tau. Brain Res Mol Brain Res 119 (2003) 201-206
13. Hamakawa H., Kato T., Shioiri T., Inubushi T., and Kato N. Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder. Psychol Med 29 (1999) 639-644
14. Hamakawa H., Murashita J., Yamada N., Inubushi T., Kato N., and Kato T. Reduced intracellular pH in the basal ganglia and whole brain measured by 31P-MRS in bipolar disorder. Psychiatry Clin Neurosci 58 (2004) 82-88
15. Hayes J.D., Flanagan J.U., and Jowsey I.R. Glutathione transferases. Annu Rev Pharmacol Toxicol 45 (2005) 51-88
16. Hayes J.D., and Strange R.C. Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology 61 (2000) 154-166
17. Hubatsch I., Ridderstrom M., and Mannervik B. Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. Biochem J 330 (1998) 175-179
18. Kato T., Takahashi S., Shioiri T., Murashita J., Hamakawa H., and Inubushi T. Reduction of brain phosphocreatine in bipolar II disorder detected by phosphorus-31 magnetic resonance spectroscopy. J Affect Disord 31 (1994) 125-133
19. Kato T., Shioiri T., Murashita J., Hamakawa H., Takahashi Y., Inubushi T., and Takahashi S. Lateralized abnormality of high energy phosphate metabolism in the frontal lobes of patients with bipolar disorder detected by phase-encoded 31P-MRS. Psychol Med 25 (1995) 557-566
20. Kato T., Murashita J., Kamiya A., Shioiri T., Kato N., and Inubushi T. Decreased brain intracellular pH measured by 31P-MRS in bipolar disorder: a confirmation in drug-free patients and correlation with white matter hyperintensity. Eur Arch Psychiatry Clin Neurosci 248 (1998) 301-306
21. King T.D., and Jope R.S. Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress. Neuroreport 16 (2005) 597-601
22. Konradi C., Eaton M., MacDonald M.L., Walsh J., Benes F.M., and Heckers S. Molecular evidence for mitochondrial dysfunction in bipolar disorder. Arch Gen Psychiatry 61 (2004) 300-308
23. Lai J.S., Zhao C., Warsh J.J., and Li P.P. Cytoprotection by lithium and valproate varies between cell types and cellular stresses. Eur J Pharmacol 539 (2006) 18-26
24. Li N., Ragheb K., Lawler G., Sturgis J., Rajwa B., Melendez J.A., and Robinson J.P. Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J Biol Chem 278 (2003) 8516-8525
25. McCubrey J.A., Lahair M.M., and Franklin R.A. Reactive oxygen species-induced activation of the MAP kinase signalling pathways. Antioxid Redox Signal 8 (2006) 1775-1789
26. Schafer M., Goodenough S., Moosmann B., and Behl C. Inhibition of glycogen synthase kinase 3 beta is involved in the resistance to oxidative stress in neuronal HT22 cells. Brain Res 1005 (2004) 84-89
27. Shao L., Young L.T., and Wang J.F. Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells. Biol Psychiatry 58 (2005) 879-884
28. Sharma R., Yang Y., Sharma A., Awasthi S., and Awasthi Y.C. Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis. Antioxid Redox Signal 6 (2004) 289-300
29. Shen H.M., and Liu Z.G. JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic Biol Med 40 (2006) 928-939
30. Sun X., Wang J.F., Tseng M., and Young L.T. Downregulation in components of mitochondrial electron transport chain in post-mortem frontal cortex from subjects with bipolar disorder. J Psychiatry Neurosci 31 (2006) 189-196
31. Wang J.F., Azzam J.E., and Young L.T. Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells. Neuroscience 116 (2003) 485-489
32. Wang J.F., Shao L., Sun X., and Young L.T. Glutathione S-transferase is a novel target for mood stabilizing drugs in primary cultured neurons. J Neurochem 88 (2004) 1477-1484
33. 2-induced cell death via coordinated regulation of stress kinases. Cancer Res 60 (2000) 4053-4057