-
1
-
-
0028793248
-
The Aberrant Behavior Checklist-Community: factor validity and effect of subject variables for adults in group homes
-
Aman M.G., Burrow W.H., Wolford P.L. The Aberrant Behavior Checklist-Community: factor validity and effect of subject variables for adults in group homes. Am. J. Ment. Retard. 1995, 100:283-292.
-
(1995)
Am. J. Ment. Retard.
, vol.100
, pp. 283-292
-
-
Aman, M.G.1
Burrow, W.H.2
Wolford, P.L.3
-
2
-
-
33744966575
-
Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses
-
Antar L.N., Li C., Zhang H., Carroll R.C., Bassell G.J. Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses. Mol. Cell. Neurosci. 2006, 32:37-48.
-
(2006)
Mol. Cell. Neurosci.
, vol.32
, pp. 37-48
-
-
Antar, L.N.1
Li, C.2
Zhang, H.3
Carroll, R.C.4
Bassell, G.J.5
-
3
-
-
84870543150
-
Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics
-
Bagni C., Tassone F., Neri G., Hagerman R. Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics. J. Clin. Invest. 2012, 122:4314-4322.
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 4314-4322
-
-
Bagni, C.1
Tassone, F.2
Neri, G.3
Hagerman, R.4
-
4
-
-
0344962385
-
Understanding fragile X syndrome: insights from animal models
-
Bakker C.E., Oostra B.A. Understanding fragile X syndrome: insights from animal models. Cytogenet. Genome Res. 2003, 100:111-123.
-
(2003)
Cytogenet. Genome Res.
, vol.100
, pp. 111-123
-
-
Bakker, C.E.1
Oostra, B.A.2
-
5
-
-
0028246435
-
Fmr1 knockout mice: a model to study fragile X mental retardation
-
Bakker C.E., Verheij C., Willemsen R., Vanderhelm R., Oerlemans F., Vermey M., Bygrave A., Hoogeveen A.T., Oostra B.A., Reyniers E., Deboulle K., Dhooge R., Cras P., Van Velzen D., Nagels G., Martin J.J., Dedeyn P.P., Darby J.K., Willems P.J. Fmr1 knockout mice: a model to study fragile X mental retardation. Cell 1994, 78:23-33.
-
(1994)
Cell
, vol.78
, pp. 23-33
-
-
Bakker, C.E.1
Verheij, C.2
Willemsen, R.3
Vanderhelm, R.4
Oerlemans, F.5
Vermey, M.6
Bygrave, A.7
Hoogeveen, A.T.8
Oostra, B.A.9
Reyniers, E.10
Deboulle, K.11
Dhooge, R.12
Cras, P.13
Van Velzen, D.14
Nagels, G.15
Martin, J.J.16
Dedeyn, P.P.17
Darby, J.K.18
Willems, P.J.19
-
6
-
-
84861849462
-
Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives
-
Bar-Nur O., Caspi I., Benvenisty N. Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives. J. Mol. Cell Biol. 2012, 4:180-183.
-
(2012)
J. Mol. Cell Biol.
, vol.4
, pp. 180-183
-
-
Bar-Nur, O.1
Caspi, I.2
Benvenisty, N.3
-
7
-
-
3042647610
-
The mGluR theory of fragile X mental retardation
-
Bear M.F., Huber K.M., Warren S.T. The mGluR theory of fragile X mental retardation. Trends Neurosci. 2004, 27:370-377.
-
(2004)
Trends Neurosci.
, vol.27
, pp. 370-377
-
-
Bear, M.F.1
Huber, K.M.2
Warren, S.T.3
-
8
-
-
33750962399
-
Effect of CX516, an AMPA-modulating compound, on cognition and behavior in fragile X syndrome: acontrolled trial
-
Berry-Kravis E., Krause S.E., Block S.S., Guter S., Wuu J., Leurgans S., Decle P., Potanos K., Cook E., Salt J., Maino D., Weinberg D., Lara R., Jardini T., Cogswell J., Johnson S.A., Hagerman R. Effect of CX516, an AMPA-modulating compound, on cognition and behavior in fragile X syndrome: acontrolled trial. J. Child Adolesc. Psychopharmacol. 2006, 16:525-540.
-
(2006)
J. Child Adolesc. Psychopharmacol.
, vol.16
, pp. 525-540
-
-
Berry-Kravis, E.1
Krause, S.E.2
Block, S.S.3
Guter, S.4
Wuu, J.5
Leurgans, S.6
Decle, P.7
Potanos, K.8
Cook, E.9
Salt, J.10
Maino, D.11
Weinberg, D.12
Lara, R.13
Jardini, T.14
Cogswell, J.15
Johnson, S.A.16
Hagerman, R.17
-
9
-
-
51249098804
-
Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome
-
Berry-Kravis E., Sumis A., Hervey C., Nelson M., Porges S.W., Weng N., Weiler I.J., Greenough W.T. Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome. J. Dev. Behav. Pediatr. 2008, 29:293-302.
-
(2008)
J. Dev. Behav. Pediatr.
, vol.29
, pp. 293-302
-
-
Berry-Kravis, E.1
Sumis, A.2
Hervey, C.3
Nelson, M.4
Porges, S.W.5
Weng, N.6
Weiler, I.J.7
Greenough, W.T.8
-
10
-
-
65949096495
-
A pilot open-label single-dose trial of fenobam in adults with fragile X syndrome
-
Berry-Kravis E.M., Hessl D., Coffey S., Hervey C., Schneider A., Yuhas J., Hutchison J., Snape M., Tranfaglia M., Nguyen D.V., Hagerman R. A pilot open-label single-dose trial of fenobam in adults with fragile X syndrome. J. Med. Genet. 2009, 46:266-271.
-
(2009)
J. Med. Genet.
, vol.46
, pp. 266-271
-
-
Berry-Kravis, E.M.1
Hessl, D.2
Coffey, S.3
Hervey, C.4
Schneider, A.5
Yuhas, J.6
Hutchison, J.7
Snape, M.8
Tranfaglia, M.9
Nguyen, D.V.10
Hagerman, R.11
-
11
-
-
84866628742
-
Effects of STX209 (Arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial
-
152ra127
-
Berry-Kravis E.M., Hessl D., Rathmell B., Zarevics P., Cherubini M., Walton-Bowen K., Mu Y., Nguyen D.V., Gonzalez-Heydrich J., Wang P.P., Carpenter R.L., Bear M.F., Hagerman R.J. Effects of STX209 (Arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci. Transl. Med. 2012, 4:152ra127.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Berry-Kravis, E.M.1
Hessl, D.2
Rathmell, B.3
Zarevics, P.4
Cherubini, M.5
Walton-Bowen, K.6
Mu, Y.7
Nguyen, D.V.8
Gonzalez-Heydrich, J.9
Wang, P.P.10
Carpenter, R.L.11
Bear, M.F.12
Hagerman, R.J.13
-
12
-
-
62149089881
-
Minocycline promotes dendritic spine maturation and improves behavioral performance in the fragile X mouse model
-
Bilousova T., Dansie L., Ngo M., Aye J., Charles J.R., Ethell D.W., Ethell I.M. Minocycline promotes dendritic spine maturation and improves behavioral performance in the fragile X mouse model. J. Med. Genet. 2008, 46:94-102.
-
(2008)
J. Med. Genet.
, vol.46
, pp. 94-102
-
-
Bilousova, T.1
Dansie, L.2
Ngo, M.3
Aye, J.4
Charles, J.R.5
Ethell, D.W.6
Ethell, I.M.7
-
13
-
-
48749093145
-
Regional rates of cerebral protein synthesis measured with L-[1-11C]leucine and PET in conscious, young adult men: normal values, variability, and reproducibility
-
Bishu S., Schmidt K.C., Burlin T., Channing M., Conant S., Huang T., Liu Z.H., Qin M., Unterman A., Xia Z., Zametkin A., Herscovitch P., Smith C.B. Regional rates of cerebral protein synthesis measured with L-[1-11C]leucine and PET in conscious, young adult men: normal values, variability, and reproducibility. J. Cereb. Blood Flow Metab. 2008, 28:1502-1513.
-
(2008)
J. Cereb. Blood Flow Metab.
, vol.28
, pp. 1502-1513
-
-
Bishu, S.1
Schmidt, K.C.2
Burlin, T.3
Channing, M.4
Conant, S.5
Huang, T.6
Liu, Z.H.7
Qin, M.8
Unterman, A.9
Xia, Z.10
Zametkin, A.11
Herscovitch, P.12
Smith, C.B.13
-
14
-
-
65549149125
-
Propofol anesthesia does not alter regional rates of cerebral protein synthesis measured with L-[1-(11)C]leucine and PET in healthy male subjects
-
Bishu S., Schmidt K.C., Burlin T.V., Channing M.A., Horowitz L., Huang T., Liu Z.H., Qin M., Vuong B.K., Unterman A.J., Xia Z., Zametkin A., Herscovitch P., Quezado Z., Smith C.B. Propofol anesthesia does not alter regional rates of cerebral protein synthesis measured with L-[1-(11)C]leucine and PET in healthy male subjects. J. Cereb. Blood Flow Metab. 2009, 29:1035-1047.
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 1035-1047
-
-
Bishu, S.1
Schmidt, K.C.2
Burlin, T.V.3
Channing, M.A.4
Horowitz, L.5
Huang, T.6
Liu, Z.H.7
Qin, M.8
Vuong, B.K.9
Unterman, A.J.10
Xia, Z.11
Zametkin, A.12
Herscovitch, P.13
Quezado, Z.14
Smith, C.B.15
-
15
-
-
0033797682
-
Varieties of repetitive behavior in autism: comparisons to mental retardation
-
Bodfish J.W., Symons F.J., Parker D.E., Lewis M.H. Varieties of repetitive behavior in autism: comparisons to mental retardation. J. Autism Dev. Disord. 2000, 30:237-243.
-
(2000)
J. Autism Dev. Disord.
, vol.30
, pp. 237-243
-
-
Bodfish, J.W.1
Symons, F.J.2
Parker, D.E.3
Lewis, M.H.4
-
16
-
-
0033802736
-
FMRP involvement in formation of synapses among cultured hippocampal neurons
-
Braun K., Segal M. FMRP involvement in formation of synapses among cultured hippocampal neurons. Cereb. Cortex 2000, 10:1045-1052.
-
(2000)
Cereb. Cortex
, vol.10
, pp. 1045-1052
-
-
Braun, K.1
Segal, M.2
-
17
-
-
57149129372
-
The clinical global impressions scale: applying a research tool in clinical practice
-
Busner J., Targum S.D. The clinical global impressions scale: applying a research tool in clinical practice. Psychiatry (Edgmont) 2007, 4:28-37.
-
(2007)
Psychiatry (Edgmont)
, vol.4
, pp. 28-37
-
-
Busner, J.1
Targum, S.D.2
-
18
-
-
48849105546
-
Parent and teacher SNAP-IV ratings of attention deficit hyperactivity disorder symptoms: psychometric properties and normative ratings from a school district sample
-
Bussing R., Fernandez M., Harwood M., Wei H., Garvan C.W., Eyberg S.M., Swanson J.M. Parent and teacher SNAP-IV ratings of attention deficit hyperactivity disorder symptoms: psychometric properties and normative ratings from a school district sample. Assessment 2008, 15:317-328.
-
(2008)
Assessment
, vol.15
, pp. 317-328
-
-
Bussing, R.1
Fernandez, M.2
Harwood, M.3
Wei, H.4
Garvan, C.W.5
Eyberg, S.M.6
Swanson, J.M.7
-
19
-
-
42649085026
-
Abnormal striatal GABA transmission in the mouse model for the fragile X syndrome
-
Centonze D., Rossi S., Mercaldo V., Napoli I., Ciotti M.T., Chiara V.D., Musella A., Prosperetti C., Calabresi P., Bernardi G., Bagni C. Abnormal striatal GABA transmission in the mouse model for the fragile X syndrome. Biol. Psychiatry 2007, 63:963-973.
-
(2007)
Biol. Psychiatry
, vol.63
, pp. 963-973
-
-
Centonze, D.1
Rossi, S.2
Mercaldo, V.3
Napoli, I.4
Ciotti, M.T.5
Chiara, V.D.6
Musella, A.7
Prosperetti, C.8
Calabresi, P.9
Bernardi, G.10
Bagni, C.11
-
20
-
-
0021812232
-
The assessment of affective disorders in children and adolescents by semistructured interview. Test-retest reliability of the schedule for affective disorders and schizophrenia for school-age children, present episode version
-
Chambers W.J., Puig-Antich J., Hirsch M., Paez P., Ambrosini P.J., Tabrizi M.A., Davies M. The assessment of affective disorders in children and adolescents by semistructured interview. Test-retest reliability of the schedule for affective disorders and schizophrenia for school-age children, present episode version. Arch. Gen. Psychiatry 1985, 42:696-702.
-
(1985)
Arch. Gen. Psychiatry
, vol.42
, pp. 696-702
-
-
Chambers, W.J.1
Puig-Antich, J.2
Hirsch, M.3
Paez, P.4
Ambrosini, P.J.5
Tabrizi, M.A.6
Davies, M.7
-
21
-
-
41049102573
-
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila
-
Chang S., Bray S.M., Li Z., Zarnescu D.C., He C., Jin P., Warren S.T. Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila. Nat. Chem. Biol. 2008, 4:256-263.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 256-263
-
-
Chang, S.1
Bray, S.M.2
Li, Z.3
Zarnescu, D.C.4
He, C.5
Jin, P.6
Warren, S.T.7
-
22
-
-
0035804765
-
Fragile X mice develop sensory hyperreactivity to auditory stimuli
-
Chen L., Toth M. Fragile X mice develop sensory hyperreactivity to auditory stimuli. Neuroscience 2001, 103:1043-1050.
-
(2001)
Neuroscience
, vol.103
, pp. 1043-1050
-
-
Chen, L.1
Toth, M.2
-
23
-
-
79952315521
-
Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment
-
Choi C.H., Schoenfeld B.P., Bell A.J., Hinchey P., Kollaros M., Gertner M.J., Woo N.H., Tranfaglia M.R., Bear M.F., Zukin R.S., McDonald T.V., Jongens T.A., McBride S.M. Pharmacological reversal of synaptic plasticity deficits in the mouse model of fragile X syndrome by group II mGluR antagonist or lithium treatment. Brain Res. 2011, 1380:106-119.
-
(2011)
Brain Res.
, vol.1380
, pp. 106-119
-
-
Choi, C.H.1
Schoenfeld, B.P.2
Bell, A.J.3
Hinchey, P.4
Kollaros, M.5
Gertner, M.J.6
Woo, N.H.7
Tranfaglia, M.R.8
Bear, M.F.9
Zukin, R.S.10
McDonald, T.V.11
Jongens, T.A.12
McBride, S.M.13
-
24
-
-
0141539482
-
Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised
-
Constantino J.N., Davis S.A., Todd R.D., Schindler M.K., Gross M.M., Brophy S.L., Metzger L.M., Shoushtari C.S., Splinter R., Reich W. Validation of a brief quantitative measure of autistic traits: comparison of the social responsiveness scale with the autism diagnostic interview-revised. J. Autism Dev. Disord. 2003, 33:427-433.
-
(2003)
J. Autism Dev. Disord.
, vol.33
, pp. 427-433
-
-
Constantino, J.N.1
Davis, S.A.2
Todd, R.D.3
Schindler, M.K.4
Gross, M.M.5
Brophy, S.L.6
Metzger, L.M.7
Shoushtari, C.S.8
Splinter, R.9
Reich, W.10
-
25
-
-
67649427508
-
Downregulation of tonic GABAergic inhibition in a mouse model of fragile X syndrome
-
Curia G., Papouin T., Seguela P., Avoli M. Downregulation of tonic GABAergic inhibition in a mouse model of fragile X syndrome. Cereb. Cortex 2009, 19:1515-1520.
-
(2009)
Cereb. Cortex
, vol.19
, pp. 1515-1520
-
-
Curia, G.1
Papouin, T.2
Seguela, P.3
Avoli, M.4
-
26
-
-
0037987767
-
Involvement of cholinergic and gabaergic systems in the fragile X knockout mice
-
D'Antuono M., Merlo D., Avoli M. Involvement of cholinergic and gabaergic systems in the fragile X knockout mice. Neuroscience 2003, 119:9-13.
-
(2003)
Neuroscience
, vol.119
, pp. 9-13
-
-
D'Antuono, M.1
Merlo, D.2
Avoli, M.3
-
27
-
-
0031014044
-
Mildly impaired water maze performance in male Fmr1 knockout mice
-
D'Hooge R., Nagels G., Franck F., Bakker C.E., Reyniers E., Storm K., Kooy R.F., Oostra B.A., Willems P.J., Dedeyn P.P. Mildly impaired water maze performance in male Fmr1 knockout mice. Neuroscience 1997, 76:367-376.
-
(1997)
Neuroscience
, vol.76
, pp. 367-376
-
-
D'Hooge, R.1
Nagels, G.2
Franck, F.3
Bakker, C.E.4
Reyniers, E.5
Storm, K.6
Kooy, R.F.7
Oostra, B.A.8
Willems, P.J.9
Dedeyn, P.P.10
-
28
-
-
33750726094
-
Decreased expression of the GABA(A) receptor in fragile X syndrome
-
D'Hulst C., De Geest N., Reeve S.P., Van Dam D., De Deyn P.P., Hassan B.A., Kooy R.F. Decreased expression of the GABA(A) receptor in fragile X syndrome. Brain Res. 2006, 1121:238-245.
-
(2006)
Brain Res.
, vol.1121
, pp. 238-245
-
-
D'Hulst, C.1
De Geest, N.2
Reeve, S.P.3
Van Dam, D.4
De Deyn, P.P.5
Hassan, B.A.6
Kooy, R.F.7
-
29
-
-
58249135425
-
Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS)
-
D'Hulst C., Heulens I., Brouwer J.R., Willemsen R., De Geest N., Reeve S.P., De Deyn P.P., Hassan B.A., Kooy R.F. Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS). Brain Res. 2009, 1253:176-183.
-
(2009)
Brain Res.
, vol.1253
, pp. 176-183
-
-
D'Hulst, C.1
Heulens, I.2
Brouwer, J.R.3
Willemsen, R.4
De Geest, N.5
Reeve, S.P.6
De Deyn, P.P.7
Hassan, B.A.8
Kooy, R.F.9
-
30
-
-
84878921815
-
Long-lasting effects of minocycline on behavior in young but not adult fragile X mice
-
Dansie L.E., Phommahaxay K., Okusanya A.G., Uwadia J., Huang M., Rotschafer S.E., Razak K.A., Ethell D.W., Ethell I.M. Long-lasting effects of minocycline on behavior in young but not adult fragile X mice. Neuroscience 2013, 246:186-198.
-
(2013)
Neuroscience
, vol.246
, pp. 186-198
-
-
Dansie, L.E.1
Phommahaxay, K.2
Okusanya, A.G.3
Uwadia, J.4
Huang, M.5
Rotschafer, S.E.6
Razak, K.A.7
Ethell, D.W.8
Ethell, I.M.9
-
31
-
-
79960779323
-
FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
-
Darnell J.C., Van Driesche S.J., Zhang C., Hung K.Y., Mele A., Fraser C.E., Stone E.F., Chen C., Fak J.J., Chi S.W., Licatalosi D.D., Richter J.D., Darnell R.B. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell 2011, 146:247-261.
-
(2011)
Cell
, vol.146
, pp. 247-261
-
-
Darnell, J.C.1
Van Driesche, S.J.2
Zhang, C.3
Hung, K.Y.4
Mele, A.5
Fraser, C.E.6
Stone, E.F.7
Chen, C.8
Fak, J.J.9
Chi, S.W.10
Licatalosi, D.D.11
Richter, J.D.12
Darnell, R.B.13
-
32
-
-
44949125523
-
Rescue of behavioral phenotype and neuronal protrusion morphology in FMR1 KO mice
-
De Vrij F.M.S., Levenga J., Van der Linde H.C., Koekkoek S.K., De Zeeuw C.I., Nelson D.L., Oostra B.A., Willemsen R. Rescue of behavioral phenotype and neuronal protrusion morphology in FMR1 KO mice. Neurobiol. Dis. 2008, 31:127-132.
-
(2008)
Neurobiol. Dis.
, vol.31
, pp. 127-132
-
-
De Vrij, F.M.S.1
Levenga, J.2
Van der Linde, H.C.3
Koekkoek, S.K.4
De Zeeuw, C.I.5
Nelson, D.L.6
Oostra, B.A.7
Willemsen, R.8
-
33
-
-
54149118376
-
The usefulness of Conners' Rating Scales-Revised in screening for attention deficit hyperactivity disorder in children with intellectual disabilities and borderline intelligence
-
Deb S., Dhaliwal A.J., Roy M. The usefulness of Conners' Rating Scales-Revised in screening for attention deficit hyperactivity disorder in children with intellectual disabilities and borderline intelligence. J. Intellect. Disabil. Res. 2008, 52:950-965.
-
(2008)
J. Intellect. Disabil. Res.
, vol.52
, pp. 950-965
-
-
Deb, S.1
Dhaliwal, A.J.2
Roy, M.3
-
34
-
-
70949101686
-
Generation and characterization of FMR1 knockout zebrafish
-
den Broeder M.J., van der Linde H., Brouwer J.R., Oostra B.A., Willemsen R., Ketting R.F. Generation and characterization of FMR1 knockout zebrafish. PLoS ONE 2009, 4:e7910.
-
(2009)
PLoS ONE
, vol.4
, pp. e7910
-
-
den Broeder, M.J.1
van der Linde, H.2
Brouwer, J.R.3
Oostra, B.A.4
Willemsen, R.5
Ketting, R.F.6
-
35
-
-
33646812582
-
Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis
-
Dhami G.K., Ferguson S.S. Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis. Pharmacol. Ther. 2006, 111:260-271.
-
(2006)
Pharmacol. Ther.
, vol.111
, pp. 260-271
-
-
Dhami, G.K.1
Ferguson, S.S.2
-
36
-
-
44449121279
-
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome
-
Dictenberg J.B., Swanger S.A., Antar L.N., Singer R.H., Bassell G.J. A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev. Cell 2008, 14:926-939.
-
(2008)
Dev. Cell
, vol.14
, pp. 926-939
-
-
Dictenberg, J.B.1
Swanger, S.A.2
Antar, L.N.3
Singer, R.H.4
Bassell, G.J.5
-
37
-
-
0037071905
-
Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest
-
Dockendorff T.C., Su H.S., McBride S.M.J., Yang Z., Choi C.H., Siwicki K.K., Sehgal A., Jongens T.A. Drosophila lacking dfmr1 activity show defects in circadian output and fail to maintain courtship interest. Neuron 2002, 34:973-984.
-
(2002)
Neuron
, vol.34
, pp. 973-984
-
-
Dockendorff, T.C.1
Su, H.S.2
McBride, S.M.J.3
Yang, Z.4
Choi, C.H.5
Siwicki, K.K.6
Sehgal, A.7
Jongens, T.A.8
-
38
-
-
84875844949
-
Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486
-
Dolan B.M., Duron S.G., Campbell D.A., Vollrath B., Rao B.S., Ko H.Y., Lin G.G., Govindarajan A., Choi S.Y., Tonegawa S. Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:5671-5676.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 5671-5676
-
-
Dolan, B.M.1
Duron, S.G.2
Campbell, D.A.3
Vollrath, B.4
Rao, B.S.5
Ko, H.Y.6
Lin, G.G.7
Govindarajan, A.8
Choi, S.Y.9
Tonegawa, S.10
-
39
-
-
37049032616
-
Correction of fragile X syndrome in mice
-
Dolen G., Osterweil E., Rao B.S., Smith G.B., Auerbach B.D., Chattarji S., Bear M.F. Correction of fragile X syndrome in mice. Neuron 2007, 56:955-962.
-
(2007)
Neuron
, vol.56
, pp. 955-962
-
-
Dolen, G.1
Osterweil, E.2
Rao, B.S.3
Smith, G.B.4
Auerbach, B.D.5
Chattarji, S.6
Bear, M.F.7
-
40
-
-
84880746947
-
High MMP-9 activity levels in fragile X syndrome are lowered by minocycline
-
Dziembowska M., Pretto D.I., Janusz A., Kaczmarek L., Leigh M.J., Gabriel N., Durbin-Johnson B., Hagerman R.J., Tassone F. High MMP-9 activity levels in fragile X syndrome are lowered by minocycline. Am. J. Med. Genet. A 2013, 161A:1897-1903.
-
(2013)
Am. J. Med. Genet. A
, vol.161 A
, pp. 1897-1903
-
-
Dziembowska, M.1
Pretto, D.I.2
Janusz, A.3
Kaczmarek, L.4
Leigh, M.J.5
Gabriel, N.6
Durbin-Johnson, B.7
Hagerman, R.J.8
Tassone, F.9
-
41
-
-
14744291567
-
Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse
-
El Idrissi A., Ding X.H., Scalia J., Trenkner E., Brown W.T., Dobkin C. Decreased GABA(A) receptor expression in the seizure-prone fragile X mouse. Neurosci. Lett. 2005, 377:141-146.
-
(2005)
Neurosci. Lett.
, vol.377
, pp. 141-146
-
-
El Idrissi, A.1
Ding, X.H.2
Scalia, J.3
Trenkner, E.4
Brown, W.T.5
Dobkin, C.6
-
42
-
-
79952315316
-
Open-label riluzole in fragile X syndrome
-
Erickson C.A., Weng N., Weiler I.J., Greenough W.T., Stigler K.A., Wink L.K., McDougle C.J. Open-label riluzole in fragile X syndrome. Brain Res. 2011, 1380:264-270.
-
(2011)
Brain Res.
, vol.1380
, pp. 264-270
-
-
Erickson, C.A.1
Weng, N.2
Weiler, I.J.3
Greenough, W.T.4
Stigler, K.A.5
Wink, L.K.6
McDougle, C.J.7
-
43
-
-
84879238323
-
Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome
-
Erickson C.A., Wink L.K., Ray B., Early M.C., Stiegelmeyer E., Mathieu-Frasier L., Patrick V., Lahiri D.K., McDougle C.J. Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome. Psychopharmacology (Berl) 2013, 228:75-84.
-
(2013)
Psychopharmacology (Berl)
, vol.228
, pp. 75-84
-
-
Erickson, C.A.1
Wink, L.K.2
Ray, B.3
Early, M.C.4
Stiegelmeyer, E.5
Mathieu-Frasier, L.6
Patrick, V.7
Lahiri, D.K.8
McDougle, C.J.9
-
45
-
-
3242790134
-
Genetic modifiers in mice: the example of the fragile X mouse model
-
Errijgers V., Kooy R.F. Genetic modifiers in mice: the example of the fragile X mouse model. Cytogenet. Genome Res. 2004, 105:448-454.
-
(2004)
Cytogenet. Genome Res.
, vol.105
, pp. 448-454
-
-
Errijgers, V.1
Kooy, R.F.2
-
46
-
-
84858749247
-
Dysregulation of fragile X mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of subjects with autism: a postmortem brain study
-
Fatemi S.H., Folsom T.D. Dysregulation of fragile X mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of subjects with autism: a postmortem brain study. Mol. Autism 2011, 2:6.
-
(2011)
Mol. Autism
, vol.2
, pp. 6
-
-
Fatemi, S.H.1
Folsom, T.D.2
-
47
-
-
0031046778
-
Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes
-
Feng Y., Gutekunst C.A., Eberhart D.E., Yi H., Warren S.T., Hersch S.M. Fragile X mental retardation protein: nucleocytoplasmic shuttling and association with somatodendritic ribosomes. J. Neurosci. 1997, 17:1539-1547.
-
(1997)
J. Neurosci.
, vol.17
, pp. 1539-1547
-
-
Feng, Y.1
Gutekunst, C.A.2
Eberhart, D.E.3
Yi, H.4
Warren, S.T.5
Hersch, S.M.6
-
48
-
-
2042473496
-
Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice
-
Frankland P.W., Wang Y., Rosner B., Shimizu T., Balleine B.W., Dykens E.M., Ornitz E.M., Silva A.J. Sensorimotor gating abnormalities in young males with fragile X syndrome and Fmr1-knockout mice. Mol. Psychiatry 2004, 9:417-425.
-
(2004)
Mol. Psychiatry
, vol.9
, pp. 417-425
-
-
Frankland, P.W.1
Wang, Y.2
Rosner, B.3
Shimizu, T.4
Balleine, B.W.5
Dykens, E.M.6
Ornitz, E.M.7
Silva, A.J.8
-
49
-
-
84862512314
-
Fragile X-associated disorders: a clinical overview
-
Gallagher A., Hallahan B. Fragile X-associated disorders: a clinical overview. J. Neurol. 2011, 259:401-413.
-
(2011)
J. Neurol.
, vol.259
, pp. 401-413
-
-
Gallagher, A.1
Hallahan, B.2
-
50
-
-
84869861822
-
Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice
-
Gantois I., Pop A.S., de Esch C.E., Buijsen R.A., Pooters T., Gomez-Mancilla B., Gasparini F., Oostra B.A., D'Hooge R., Willemsen R. Chronic administration of AFQ056/Mavoglurant restores social behaviour in Fmr1 knockout mice. Behav. Brain Res. 2013, 239:72-79.
-
(2013)
Behav. Brain Res.
, vol.239
, pp. 72-79
-
-
Gantois, I.1
Pop, A.S.2
de Esch, C.E.3
Buijsen, R.A.4
Pooters, T.5
Gomez-Mancilla, B.6
Gasparini, F.7
Oostra, B.A.8
D'Hooge, R.9
Willemsen, R.10
-
52
-
-
50649095000
-
Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure
-
Gatto C.L., Broadie K. Temporal requirements of the fragile X mental retardation protein in the regulation of synaptic structure. Development 2008, 135:2637-2648.
-
(2008)
Development
, vol.135
, pp. 2637-2648
-
-
Gatto, C.L.1
Broadie, K.2
-
53
-
-
25644434915
-
A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome
-
Giuffrida R., Musumeci S., D'Antoni S., Bonaccorso C.M., Giuffrida-Stella A.M., Oostra B.A., Catania M.V. A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome. J. Neurosci. 2005, 25:8908-8916.
-
(2005)
J. Neurosci.
, vol.25
, pp. 8908-8916
-
-
Giuffrida, R.1
Musumeci, S.2
D'Antoni, S.3
Bonaccorso, C.M.4
Giuffrida-Stella, A.M.5
Oostra, B.A.6
Catania, M.V.7
-
54
-
-
84863333644
-
Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model
-
Goebel-Goody S.M., Wilson-Wallis E.D., Royston S., Tagliatela S.M., Naegele J.R., Lombroso P.J. Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model. Genes Brain Behav 2012, 11:586-600.
-
(2012)
Genes Brain Behav
, vol.11
, pp. 586-600
-
-
Goebel-Goody, S.M.1
Wilson-Wallis, E.D.2
Royston, S.3
Tagliatela, S.M.4
Naegele, J.R.5
Lombroso, P.J.6
-
55
-
-
39049094764
-
Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP)
-
Gothelf D., Furfaro J.A., Hoeft F., Eckert M.A., Hall S.S., O'Hara R., Erba H.W., Ringel J., Hayashi K.M., Patnaik S., Golianu B., Kraemer H.C., Thompson P.M., Piven J., Reiss A.L. Neuroanatomy of fragile X syndrome is associated with aberrant behavior and the fragile X mental retardation protein (FMRP). Ann. Neurol. 2007, 63:40-51.
-
(2007)
Ann. Neurol.
, vol.63
, pp. 40-51
-
-
Gothelf, D.1
Furfaro, J.A.2
Hoeft, F.3
Eckert, M.A.4
Hall, S.S.5
O'Hara, R.6
Erba, H.W.7
Ringel, J.8
Hayashi, K.M.9
Patnaik, S.10
Golianu, B.11
Kraemer, H.C.12
Thompson, P.M.13
Piven, J.14
Reiss, A.L.15
-
56
-
-
79957461232
-
Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome
-
Greco C.M., Navarro C.S., Hunsaker M.R., Maezawa I., Shuler J.F., Tassone F., Delany M., Au J.W., Berman R.F., Jin L.W., Schumann C., Hagerman P.J., Hagerman R.J. Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome. Mol. Autism 2011, 2:2.
-
(2011)
Mol. Autism
, vol.2
, pp. 2
-
-
Greco, C.M.1
Navarro, C.S.2
Hunsaker, M.R.3
Maezawa, I.4
Shuler, J.F.5
Tassone, F.6
Delany, M.7
Au, J.W.8
Berman, R.F.9
Jin, L.W.10
Schumann, C.11
Hagerman, P.J.12
Hagerman, R.J.13
-
57
-
-
84860568814
-
Excess protein synthesis in FXS patient lymphoblastoid cells can be rescued with a p110beta-selective inhibitor
-
Gross C., Bassell G.J. Excess protein synthesis in FXS patient lymphoblastoid cells can be rescued with a p110beta-selective inhibitor. Mol. Med. 2012, 18:336-345.
-
(2012)
Mol. Med.
, vol.18
, pp. 336-345
-
-
Gross, C.1
Bassell, G.J.2
-
58
-
-
84856078399
-
Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond
-
Gross C., Berry-Kravis E.M., Bassell G.J. Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond. Neuropsychopharmacology 2012, 37:178-195.
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 178-195
-
-
Gross, C.1
Berry-Kravis, E.M.2
Bassell, G.J.3
-
59
-
-
77956209418
-
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile x syndrome
-
Gross C., Nakamoto M., Yao X., Chan C.B., Yim S.Y., Ye K., Warren S.T., Bassell G.J. Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile x syndrome. J. Neurosci. 2010, 30:10624-10638.
-
(2010)
J. Neurosci.
, vol.30
, pp. 10624-10638
-
-
Gross, C.1
Nakamoto, M.2
Yao, X.3
Chan, C.B.4
Yim, S.Y.5
Ye, K.6
Warren, S.T.7
Bassell, G.J.8
-
60
-
-
0031941351
-
Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients
-
Hazlett E.A., Buchsbaum M.S., Haznedar M.M., Singer M.B., Germans M.K., Schnur D.B., Jimenez E.A., Buchsbaum B.R., Troyer B.T. Prefrontal cortex glucose metabolism and startle eyeblink modification abnormalities in unmedicated schizophrenia patients. Psychophysiology 1998, 35:186-198.
-
(1998)
Psychophysiology
, vol.35
, pp. 186-198
-
-
Hazlett, E.A.1
Buchsbaum, M.S.2
Haznedar, M.M.3
Singer, M.B.4
Germans, M.K.5
Schnur, D.B.6
Jimenez, E.A.7
Buchsbaum, B.R.8
Troyer, B.T.9
-
61
-
-
84866615813
-
Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABA(B) receptors with arbaclofen
-
152ra128
-
Henderson C., Wijetunge L., Kinoshita M.N., Shumway M., Hammond R.S., Postma F.R., Brynczka C., Rush R., Thomas A., Paylor R., Warren S.T., Vanderklish P.W., Kind P.C., Carpenter R.L., Bear M.F., Healy A.M. Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABA(B) receptors with arbaclofen. Sci. Transl. Med. 2012, 4:152ra128.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Henderson, C.1
Wijetunge, L.2
Kinoshita, M.N.3
Shumway, M.4
Hammond, R.S.5
Postma, F.R.6
Brynczka, C.7
Rush, R.8
Thomas, A.9
Paylor, R.10
Warren, S.T.11
Vanderklish, P.W.12
Kind, P.C.13
Carpenter, R.L.14
Bear, M.F.15
Healy, A.M.16
-
62
-
-
66649136789
-
Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment
-
Hessl D., Berry-Kravis E., Cordeiro L., Yuhas J., Ornitz E.M., Campbell A., Chruscinski E., Hervey C., Long J.M., Hagerman R.J. Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 2009, 150B:545-553.
-
(2009)
Am. J. Med. Genet. B: Neuropsychiatr. Genet.
, vol.150 B
, pp. 545-553
-
-
Hessl, D.1
Berry-Kravis, E.2
Cordeiro, L.3
Yuhas, J.4
Ornitz, E.M.5
Campbell, A.6
Chruscinski, E.7
Hervey, C.8
Long, J.M.9
Hagerman, R.J.10
-
64
-
-
84856578911
-
Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model
-
Heulens I., D'Hulst C., Van Dam D., De Deyn P.P., Kooy R.F. Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model. Behav. Brain Res. 2012, 229:244-249.
-
(2012)
Behav. Brain Res.
, vol.229
, pp. 244-249
-
-
Heulens, I.1
D'Hulst, C.2
Van Dam, D.3
De Deyn, P.P.4
Kooy, R.F.5
-
65
-
-
84880920687
-
Craniofacial characteristics of fragile X syndrome in mouse and man
-
Heulens I., Suttie M., Postnov A., De Clerck N., Perrotta C.S., Mattina T., Faravelli F., Forzano F., Kooy R.F., Hammond P. Craniofacial characteristics of fragile X syndrome in mouse and man. Eur. J. Hum. Genet. 2013, 21:816-823.
-
(2013)
Eur. J. Hum. Genet.
, vol.21
, pp. 816-823
-
-
Heulens, I.1
Suttie, M.2
Postnov, A.3
De Clerck, N.4
Perrotta, C.S.5
Mattina, T.6
Faravelli, F.7
Forzano, F.8
Kooy, R.F.9
Hammond, P.10
-
66
-
-
0025720084
-
Analysis of neocortex in three males with the fragile X syndrome
-
Hinton V.J., Brown W.T., Wisniewski K., Rudelli R.D. Analysis of neocortex in three males with the fragile X syndrome. Am. J. Med. Genet. 1991, 41:289-294.
-
(1991)
Am. J. Med. Genet.
, vol.41
, pp. 289-294
-
-
Hinton, V.J.1
Brown, W.T.2
Wisniewski, K.3
Rudelli, R.D.4
-
67
-
-
84859420878
-
Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome
-
Hoeffer C.A., Sanchez E., Hagerman R.J., Mu Y., Nguyen D.V., Wong H., Whelan A.M., Zukin R.S., Klann E., Tassone F. Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome. Genes Brain Behav. 2012, 11:332-341.
-
(2012)
Genes Brain Behav.
, vol.11
, pp. 332-341
-
-
Hoeffer, C.A.1
Sanchez, E.2
Hagerman, R.J.3
Mu, Y.4
Nguyen, D.V.5
Wong, H.6
Whelan, A.M.7
Zukin, R.S.8
Klann, E.9
Tassone, F.10
-
68
-
-
34249804167
-
Fronto-striatal dysfunction and potential compensatory mechanisms in male adolescents with fragile X syndrome
-
Hoeft F., Hernandez A., Parthasarathy S., Watson C.L., Hall S.S., Reiss A.L. Fronto-striatal dysfunction and potential compensatory mechanisms in male adolescents with fragile X syndrome. Hum. Brain Mapp. 2007, 28:543-554.
-
(2007)
Hum. Brain Mapp.
, vol.28
, pp. 543-554
-
-
Hoeft, F.1
Hernandez, A.2
Parthasarathy, S.3
Watson, C.L.4
Hall, S.S.5
Reiss, A.L.6
-
69
-
-
0037188502
-
Altered synaptic plasticity in a mouse model of fragile X mental retardation
-
Huber K.M., Gallagher S.M., Warren S.T., Bear M.F. Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:7746-7750.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7746-7750
-
-
Huber, K.M.1
Gallagher, S.M.2
Warren, S.T.3
Bear, M.F.4
-
70
-
-
0034942216
-
Chemical induction of mGluR5- and protein synthesis-dependent long-term depression in hippocampal area CA1
-
Huber K.M., Roder J.C., Bear M.F. Chemical induction of mGluR5- and protein synthesis-dependent long-term depression in hippocampal area CA1. J. Neurophysiol. 2001, 86:321-325.
-
(2001)
J. Neurophysiol.
, vol.86
, pp. 321-325
-
-
Huber, K.M.1
Roder, J.C.2
Bear, M.F.3
-
71
-
-
0033797832
-
Dendritic spine structural anomalies in fragile-X mental retardation syndrome
-
Irwin S.A., Galvez R., Greenough W.T. Dendritic spine structural anomalies in fragile-X mental retardation syndrome. Cereb. Cortex 2000, 10:1038-1044.
-
(2000)
Cereb. Cortex
, vol.10
, pp. 1038-1044
-
-
Irwin, S.A.1
Galvez, R.2
Greenough, W.T.3
-
72
-
-
0035863624
-
Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination
-
Irwin S.A., Patel B., Idupulapati M., Harris J.B., Crisostomo R.A., Larsen B.P., Kooy F., Willems P.J., Cras P., Kozlowski P.B., Swain R.A., Weiler I.J., Greenough W.T. Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination. Am. J. Med. Genet. 2001, 98:161-167.
-
(2001)
Am. J. Med. Genet.
, vol.98
, pp. 161-167
-
-
Irwin, S.A.1
Patel, B.2
Idupulapati, M.3
Harris, J.B.4
Crisostomo, R.A.5
Larsen, B.P.6
Kooy, F.7
Willems, P.J.8
Cras, P.9
Kozlowski, P.B.10
Swain, R.A.11
Weiler, I.J.12
Greenough, W.T.13
-
73
-
-
0031029570
-
GABA(B)-mediated presynaptic inhibition of excitatory transmission and synaptic vesicle dynamics in cultured hippocampal neurons
-
Isaacson J.S., Hille B. GABA(B)-mediated presynaptic inhibition of excitatory transmission and synaptic vesicle dynamics in cultured hippocampal neurons. Neuron 1997, 18:143-152.
-
(1997)
Neuron
, vol.18
, pp. 143-152
-
-
Isaacson, J.S.1
Hille, B.2
-
74
-
-
78650937072
-
Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056
-
64ra61
-
Jacquemont S., Curie A., des Portes V., Torrioli M.G., Berry-Kravis E., Hagerman R.J., Ramos F.J., Cornish K., He Y., Paulding C., Neri G., Chen F., Hadjikhani N., Martinet D., Meyer J., Beckmann J.S., Delange K., Brun A., Bussy G., Gasparini F., Hilse T., Floesser A., Branson J., Bilbe G., Johns D., Gomez-Mancilla B. Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056. Sci. Transl. Med. 2011, 3:64ra61.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Jacquemont, S.1
Curie, A.2
des Portes, V.3
Torrioli, M.G.4
Berry-Kravis, E.5
Hagerman, R.J.6
Ramos, F.J.7
Cornish, K.8
He, Y.9
Paulding, C.10
Neri, G.11
Chen, F.12
Hadjikhani, N.13
Martinet, D.14
Meyer, J.15
Beckmann, J.S.16
Delange, K.17
Brun, A.18
Bussy, G.19
Gasparini, F.20
Hilse, T.21
Floesser, A.22
Branson, J.23
Bilbe, G.24
Johns, D.25
Gomez-Mancilla, B.26
more..
-
75
-
-
84867013830
-
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome
-
Jung K.M., Sepers M., Henstridge C.M., Lassalle O., Neuhofer D., Martin H., Ginger M., Frick A., Dipatrizio N.V., Mackie K., Katona I., Piomelli D., Manzoni O.J. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nat. Commun. 2012, 3:1080.
-
(2012)
Nat. Commun.
, vol.3
, pp. 1080
-
-
Jung, K.M.1
Sepers, M.2
Henstridge, C.M.3
Lassalle, O.4
Neuhofer, D.5
Martin, H.6
Ginger, M.7
Frick, A.8
Dipatrizio, N.V.9
Mackie, K.10
Katona, I.11
Piomelli, D.12
Manzoni, O.J.13
-
76
-
-
84866415765
-
Learning and memory deficits consequent to reduction of the fragile x mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila
-
Kanellopoulos A.K., Semelidou O., Kotini A.G., Anezaki M., Skoulakis E.M. Learning and memory deficits consequent to reduction of the fragile x mental retardation protein result from metabotropic glutamate receptor-mediated inhibition of cAMP signaling in Drosophila. J. Neurosci. 2012, 32:13111-13124.
-
(2012)
J. Neurosci.
, vol.32
, pp. 13111-13124
-
-
Kanellopoulos, A.K.1
Semelidou, O.2
Kotini, A.G.3
Anezaki, M.4
Skoulakis, E.M.5
-
77
-
-
65649115029
-
Directed differentiation of human-induced pluripotent stem cells generates active motor neurons
-
Karumbayaram S., Novitch B.G., Patterson M., Umbach J.A., Richter L., Lindgren A., Conway A.E., Clark A.T., Goldman S.A., Plath K., Wiedau-Pazos M., Kornblum H.I., Lowry W.E. Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells 2009, 27:806-811.
-
(2009)
Stem Cells
, vol.27
, pp. 806-811
-
-
Karumbayaram, S.1
Novitch, B.G.2
Patterson, M.3
Umbach, J.A.4
Richter, L.5
Lindgren, A.6
Conway, A.E.7
Clark, A.T.8
Goldman, S.A.9
Plath, K.10
Wiedau-Pazos, M.11
Kornblum, H.I.12
Lowry, W.E.13
-
78
-
-
0033797735
-
Dendritic anomalies in disorders associated with mental retardation
-
Kaufmann W.E., Moser H.W. Dendritic anomalies in disorders associated with mental retardation. Cereb. Cortex 2000, 10:981-991.
-
(2000)
Cereb. Cortex
, vol.10
, pp. 981-991
-
-
Kaufmann, W.E.1
Moser, H.W.2
-
79
-
-
61749092234
-
Cholinergic dysfunction in fragile X syndrome and potential intervention: a preliminary (1)H MRS study
-
Kesler S.R., Lightbody A.A., Reiss A.L. Cholinergic dysfunction in fragile X syndrome and potential intervention: a preliminary (1)H MRS study. Am. J. Med. Genet. A 2009, 149A:403-407.
-
(2009)
Am. J. Med. Genet. A
, vol.149 A
, pp. 403-407
-
-
Kesler, S.R.1
Lightbody, A.A.2
Reiss, A.L.3
-
80
-
-
84894277862
-
Fear-Specific Amygdala Function in Children and Adolescents on the Fragile X Spectrum: A Dosage Response of the FMR1 Gene
-
Kim S.Y., Burris J., Bassal F., Koldewyn K., Chattarji S., Tassone F., Hessl D., Rivera S.M. Fear-Specific Amygdala Function in Children and Adolescents on the Fragile X Spectrum: A Dosage Response of the FMR1 Gene. Cereb. Cortex 2013, 10.1093/cercor/bhs341.
-
(2013)
Cereb. Cortex
-
-
Kim, S.Y.1
Burris, J.2
Bassal, F.3
Koldewyn, K.4
Chattarji, S.5
Tassone, F.6
Hessl, D.7
Rivera, S.M.8
-
81
-
-
23044503253
-
Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome
-
Koekkoek S.K., Yamaguchi K., Milojkovic B.A., Dortland B.R., Ruigrok T.J., Maex R., De Graaf W., Smit A.E., Vanderwerf F., Bakker C.E., Willemsen R., Ikeda T., Kakizawa S., Onodera K., Nelson D.L., Mientjes E., Joosten M., De Schutter E., Oostra B.A., Ito M., De Zeeuw C.I. Deletion of FMR1 in Purkinje cells enhances parallel fiber LTD, enlarges spines, and attenuates cerebellar eyelid conditioning in fragile X syndrome. Neuron 2005, 47:339-352.
-
(2005)
Neuron
, vol.47
, pp. 339-352
-
-
Koekkoek, S.K.1
Yamaguchi, K.2
Milojkovic, B.A.3
Dortland, B.R.4
Ruigrok, T.J.5
Maex, R.6
De Graaf, W.7
Smit, A.E.8
Vanderwerf, F.9
Bakker, C.E.10
Willemsen, R.11
Ikeda, T.12
Kakizawa, S.13
Onodera, K.14
Nelson, D.L.15
Mientjes, E.16
Joosten, M.17
De Schutter, E.18
Oostra, B.A.19
Ito, M.20
De Zeeuw, C.I.21
more..
-
82
-
-
0037372019
-
Of mice and the fragile X syndrome
-
Kooy R.F. Of mice and the fragile X syndrome. Trends Genet. 2003, 19:148-154.
-
(2003)
Trends Genet.
, vol.19
, pp. 148-154
-
-
Kooy, R.F.1
-
83
-
-
79952301339
-
Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome
-
Krueger D.D., Osterweil E.K., Chen S.P., Tye L.D., Bear M.F. Cognitive dysfunction and prefrontal synaptic abnormalities in a mouse model of fragile X syndrome. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:2587-2592.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 2587-2592
-
-
Krueger, D.D.1
Osterweil, E.K.2
Chen, S.P.3
Tye, L.D.4
Bear, M.F.5
-
84
-
-
84859293639
-
Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex
-
Kwan K.Y., Lam M.M., Johnson M.B., Dube U., Shim S., Rasin M.R., Sousa A.M., Fertuzinhos S., Chen J.G., Arellano J.I., Chan D.W., Pletikos M., Vasung L., Rowitch D.H., Huang E.J., Schwartz M.L., Willemsen R., Oostra B.A., Rakic P., Heffer M., Kostovic I., Judas M., Sestan N. Species-dependent posttranscriptional regulation of NOS1 by FMRP in the developing cerebral cortex. Cell 2012, 149:899-911.
-
(2012)
Cell
, vol.149
, pp. 899-911
-
-
Kwan, K.Y.1
Lam, M.M.2
Johnson, M.B.3
Dube, U.4
Shim, S.5
Rasin, M.R.6
Sousa, A.M.7
Fertuzinhos, S.8
Chen, J.G.9
Arellano, J.I.10
Chan, D.W.11
Pletikos, M.12
Vasung, L.13
Rowitch, D.H.14
Huang, E.J.15
Schwartz, M.L.16
Willemsen, R.17
Oostra, B.A.18
Rakic, P.19
Heffer, M.20
Kostovic, I.21
Judas, M.22
Sestan, N.23
more..
-
85
-
-
0035864826
-
Evidence that fragile X mental retardation protein is a negative regulator of translation
-
Laggerbauer B., Ostareck D., Keidel E.M., Ostareck-Lederer A., Fischer U. Evidence that fragile X mental retardation protein is a negative regulator of translation. Hum. Mol. Genet. 2001, 10:329-338.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 329-338
-
-
Laggerbauer, B.1
Ostareck, D.2
Keidel, E.M.3
Ostareck-Lederer, A.4
Fischer, U.5
-
86
-
-
84876358587
-
A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile X syndrome
-
Leigh M.J., Nguyen D.V., Mu Y., Winarni T.I., Schneider A., Chechi T., Polussa J., Doucet P., Tassone F., Rivera S.M., Hessl D., Hagerman R.J. A randomized double-blind, placebo-controlled trial of minocycline in children and adolescents with fragile X syndrome. J. Dev. Behav. Pediatr. 2013, 34:147-155.
-
(2013)
J. Dev. Behav. Pediatr.
, vol.34
, pp. 147-155
-
-
Leigh, M.J.1
Nguyen, D.V.2
Mu, Y.3
Winarni, T.I.4
Schneider, A.5
Chechi, T.6
Polussa, J.7
Doucet, P.8
Tassone, F.9
Rivera, S.M.10
Hessl, D.11
Hagerman, R.J.12
-
87
-
-
84877302187
-
Treating Fragile X syndrome with the diuretic bumetanide: a case report
-
Lemonnier E., Robin G., Degrez C., Tyzio R., Grandgeorge M., Ben-Ari Y. Treating Fragile X syndrome with the diuretic bumetanide: a case report. Acta Paediatr. 2013, 102:e288-e290.
-
(2013)
Acta Paediatr.
, vol.102
, pp. e288-e290
-
-
Lemonnier, E.1
Robin, G.2
Degrez, C.3
Tyzio, R.4
Grandgeorge, M.5
Ben-Ari, Y.6
-
88
-
-
79954629349
-
AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome
-
Levenga J., Hayashi S., de Vrij F.M., Koekkoek S.K., van der Linde H.C., Nieuwenhuizen I., Song C., Buijsen R.A., Pop A.S., GomezMancilla B., Nelson D.L., Willemsen R., Gasparini F., Oostra B.A. AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome. Neurobiol. Dis. 2011, 42:311-317.
-
(2011)
Neurobiol. Dis.
, vol.42
, pp. 311-317
-
-
Levenga, J.1
Hayashi, S.2
de Vrij, F.M.3
Koekkoek, S.K.4
van der Linde, H.C.5
Nieuwenhuizen, I.6
Song, C.7
Buijsen, R.A.8
Pop, A.S.9
GomezMancilla, B.10
Nelson, D.L.11
Willemsen, R.12
Gasparini, F.13
Oostra, B.A.14
-
89
-
-
0035368955
-
The fragile X mental retardation protein inhibits translation via interacting with mRNA
-
Li Z., Zhang Y., Ku L., Wilkinson K.D., Warren S.T., Feng Y. The fragile X mental retardation protein inhibits translation via interacting with mRNA. Nucleic Acids Res. 2001, 29:2276-2283.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2276-2283
-
-
Li, Z.1
Zhang, Y.2
Ku, L.3
Wilkinson, K.D.4
Warren, S.T.5
Feng, Y.6
-
90
-
-
79956013568
-
Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome
-
Liu Z.H., Chuang D.M., Smith C.B. Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome. Int. J. Neuropsychopharmacol. 2010, 1-13.
-
(2010)
Int. J. Neuropsychopharmacol.
, pp. 1-13
-
-
Liu, Z.H.1
Chuang, D.M.2
Smith, C.B.3
-
91
-
-
84878004228
-
Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?
-
Lohith T.G., Osterweil E.K., Fujita M., Jenko K.J., Bear M.F., Innis R.B. Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?. Mol. Autism 2013, 4:15.
-
(2013)
Mol. Autism
, vol.4
, pp. 15
-
-
Lohith, T.G.1
Osterweil, E.K.2
Fujita, M.3
Jenko, K.J.4
Bear, M.F.5
Innis, R.B.6
-
92
-
-
0024369122
-
Autism diagnostic observation schedule: a standardized observation of communicative and social behavior
-
Lord C., Rutter M., Goode S., Heemsbergen J., Jordan H., Mawhood L., Schopler E. Autism diagnostic observation schedule: a standardized observation of communicative and social behavior. J. Autism Dev. Disord. 1989, 19:185-212.
-
(1989)
J. Autism Dev. Disord.
, vol.19
, pp. 185-212
-
-
Lord, C.1
Rutter, M.2
Goode, S.3
Heemsbergen, J.4
Jordan, H.5
Mawhood, L.6
Schopler, E.7
-
93
-
-
0014517848
-
A marker X-chromosome
-
Lubs H.A. A marker X-chromosome. Am. J. Hum. Genet. 1969, 21:231-244.
-
(1969)
Am. J. Hum. Genet.
, vol.21
, pp. 231-244
-
-
Lubs, H.A.1
-
94
-
-
0034199405
-
Phenotypic checklist to screen for fragile X syndrome in people with mental retardation
-
Maes B., Fryns J.P., Ghesquiere P., Borghgraef M. Phenotypic checklist to screen for fragile X syndrome in people with mental retardation. Ment. Retard. 2000, 38:207-215.
-
(2000)
Ment. Retard.
, vol.38
, pp. 207-215
-
-
Maes, B.1
Fryns, J.P.2
Ghesquiere, P.3
Borghgraef, M.4
-
95
-
-
5344241223
-
LTP and LTD: an embarrassment of riches
-
Malenka R.C., Bear M.F. LTP and LTD: an embarrassment of riches. Neuron 2004, 44:5-21.
-
(2004)
Neuron
, vol.44
, pp. 5-21
-
-
Malenka, R.C.1
Bear, M.F.2
-
96
-
-
0000524625
-
A pedigree of mental defect showing sex-linkage
-
Martin J.P., Bell J. A pedigree of mental defect showing sex-linkage. J. Neurol. Psychiatry 1943, 6:154-157.
-
(1943)
J. Neurol. Psychiatry
, vol.6
, pp. 154-157
-
-
Martin, J.P.1
Bell, J.2
-
97
-
-
0024109728
-
Clinical applications of visual analogue scales: a critical review
-
McCormack H.M., Horne D.J., Sheather S. Clinical applications of visual analogue scales: a critical review. Psychol. Med. 1988, 18:1007-1019.
-
(1988)
Psychol. Med.
, vol.18
, pp. 1007-1019
-
-
McCormack, H.M.1
Horne, D.J.2
Sheather, S.3
-
98
-
-
1542723394
-
Frontostriatal deficits in fragile X syndrome: relation to FMR1 gene expression
-
Menon V., Leroux J., White C.D., Reiss A.L. Frontostriatal deficits in fragile X syndrome: relation to FMR1 gene expression. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:3615-3620.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 3615-3620
-
-
Menon, V.1
Leroux, J.2
White, C.D.3
Reiss, A.L.4
-
99
-
-
0024319574
-
Use of the childhood autism rating scale with autistic adolescents and adults
-
Mesibov G.B., Schopler E., Schaffer B., Michal N. Use of the childhood autism rating scale with autistic adolescents and adults. J. Am. Acad. Child Adolesc. Psychiatry 1989, 28:538-541.
-
(1989)
J. Am. Acad. Child Adolesc. Psychiatry
, vol.28
, pp. 538-541
-
-
Mesibov, G.B.1
Schopler, E.2
Schaffer, B.3
Michal, N.4
-
100
-
-
84859628864
-
Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice
-
Michalon A., Sidorov M., Ballard T.M., Ozmen L., Spooren W., Wettstein J.G., Jaeschke G., Bear M.F., Lindemann L. Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. Neuron 2012, 74:49-56.
-
(2012)
Neuron
, vol.74
, pp. 49-56
-
-
Michalon, A.1
Sidorov, M.2
Ballard, T.M.3
Ozmen, L.4
Spooren, W.5
Wettstein, J.G.6
Jaeschke, G.7
Bear, M.F.8
Lindemann, L.9
-
101
-
-
33244492432
-
The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo
-
Mientjes E.J., Nieuwenhuizen I., Kirkpatrick L., Zu T., Hoogeveen-Westerveld M., Severijnen L., Rife M., Willemsen R., Nelson D.L., Oostra B.A. The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo. Neurobiol. Dis. 2006, 21:549-555.
-
(2006)
Neurobiol. Dis.
, vol.21
, pp. 549-555
-
-
Mientjes, E.J.1
Nieuwenhuizen, I.2
Kirkpatrick, L.3
Zu, T.4
Hoogeveen-Westerveld, M.5
Severijnen, L.6
Rife, M.7
Willemsen, R.8
Nelson, D.L.9
Oostra, B.A.10
-
102
-
-
58849126410
-
Elevated glycogen synthase kinase-3 activity in fragile X mice: key metabolic regulator with evidence for treatment potential
-
Min W.W., Yuskaitis C.J., Yan Q., Sikorski C., Chen S., Jope R.S., Bauchwitz R.P. Elevated glycogen synthase kinase-3 activity in fragile X mice: key metabolic regulator with evidence for treatment potential. Neuropharmacology 2009, 56:463-472.
-
(2009)
Neuropharmacology
, vol.56
, pp. 463-472
-
-
Min, W.W.1
Yuskaitis, C.J.2
Yan, Q.3
Sikorski, C.4
Chen, S.5
Jope, R.S.6
Bauchwitz, R.P.7
-
103
-
-
34249064936
-
Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome
-
Muddashetty R.S., Kelic S., Gross C., Xu M., Bassell G.J. Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. J. Neurosci. 2007, 27:5338-5348.
-
(2007)
J. Neurosci.
, vol.27
, pp. 5338-5348
-
-
Muddashetty, R.S.1
Kelic, S.2
Gross, C.3
Xu, M.4
Bassell, G.J.5
-
104
-
-
0021377793
-
Semel and Wiig's CELF: construct validity?
-
Muma J.R. Semel and Wiig's CELF: construct validity?. J. Speech Hear. Disord. 1984, 49:101-104.
-
(1984)
J. Speech Hear. Disord.
, vol.49
, pp. 101-104
-
-
Muma, J.R.1
-
105
-
-
0033987591
-
Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome
-
Musumeci S.A., Bosco P., Calabrese G., Bakker C., De Sarro G.B., Elia M., Ferri R., Oostra B.A. Audiogenic seizures susceptibility in transgenic mice with fragile X syndrome. Epilepsia 2000, 41:19-23.
-
(2000)
Epilepsia
, vol.41
, pp. 19-23
-
-
Musumeci, S.A.1
Bosco, P.2
Calabrese, G.3
Bakker, C.4
De Sarro, G.B.5
Elia, M.6
Ferri, R.7
Oostra, B.A.8
-
106
-
-
0021082582
-
Stability, concurrent and predictive validity of the PPVT-R
-
Naglieri J.A., Pfeiffer S.I. Stability, concurrent and predictive validity of the PPVT-R. J. Clin. Psychol. 1983, 39:965-967.
-
(1983)
J. Clin. Psychol.
, vol.39
, pp. 965-967
-
-
Naglieri, J.A.1
Pfeiffer, S.I.2
-
107
-
-
34848890329
-
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors
-
Nakamoto M., Nalavadi V., Epstein M.P., Narayanan U., Bassell G.J., Warren S.T. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:15537-15542.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 15537-15542
-
-
Nakamoto, M.1
Nalavadi, V.2
Epstein, M.P.3
Narayanan, U.4
Bassell, G.J.5
Warren, S.T.6
-
108
-
-
84874854034
-
Behavioral and synaptic circuit features in a zebrafish model of fragile x syndrome
-
Ng M.C., Yang Y.L., Lu K.T. Behavioral and synaptic circuit features in a zebrafish model of fragile x syndrome. PLoS ONE 2013, 8:e51456.
-
(2013)
PLoS ONE
, vol.8
, pp. e51456
-
-
Ng, M.C.1
Yang, Y.L.2
Lu, K.T.3
-
109
-
-
77954851827
-
Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile x syndrome
-
Olmos-Serrano J.L., Paluszkiewicz S.M., Martin B.S., Kaufmann W.E., Corbin J.G., Huntsman M.M. Defective GABAergic neurotransmission and pharmacological rescue of neuronal hyperexcitability in the amygdala in a mouse model of fragile x syndrome. J. Neurosci. 2010, 30:9929-9938.
-
(2010)
J. Neurosci.
, vol.30
, pp. 9929-9938
-
-
Olmos-Serrano, J.L.1
Paluszkiewicz, S.M.2
Martin, B.S.3
Kaufmann, W.E.4
Corbin, J.G.5
Huntsman, M.M.6
-
110
-
-
84872716739
-
Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile x syndrome
-
Osterweil E.K., Chuang S.C., Chubykin A.A., Sidorov M., Bianchi R., Wong R.K., Bear M.F. Lovastatin corrects excess protein synthesis and prevents epileptogenesis in a mouse model of fragile x syndrome. Neuron 2013, 77:243-250.
-
(2013)
Neuron
, vol.77
, pp. 243-250
-
-
Osterweil, E.K.1
Chuang, S.C.2
Chubykin, A.A.3
Sidorov, M.4
Bianchi, R.5
Wong, R.K.6
Bear, M.F.7
-
111
-
-
78449259794
-
Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome
-
Osterweil E.K., Krueger D.D., Reinhold K., Bear M.F. Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome. J. Neurosci. 2010, 30:15616-15627.
-
(2010)
J. Neurosci.
, vol.30
, pp. 15616-15627
-
-
Osterweil, E.K.1
Krueger, D.D.2
Reinhold, K.3
Bear, M.F.4
-
112
-
-
67649834454
-
Increased GABAB receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures
-
Pacey L.K., Heximer S.P., Hampson D.R. Increased GABAB receptor-mediated signaling reduces the susceptibility of fragile X knockout mice to audiogenic seizures. Mol. Pharmacol. 2009, 76:18-24.
-
(2009)
Mol. Pharmacol.
, vol.76
, pp. 18-24
-
-
Pacey, L.K.1
Heximer, S.P.2
Hampson, D.R.3
-
113
-
-
80052166631
-
Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome
-
Pacey L.K., Tharmalingam S., Hampson D.R. Subchronic administration and combination metabotropic glutamate and GABAB receptor drug therapy in fragile X syndrome. J. Pharmacol. Exp. Ther. 2011, 338:897-905.
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.338
, pp. 897-905
-
-
Pacey, L.K.1
Tharmalingam, S.2
Hampson, D.R.3
-
114
-
-
6944247816
-
The Drosophila fragile x gene negatively regulates neuronal elaboration and synaptic differentiation
-
Pan L., Zhang Y.Q., Woodruff E., Broadie K. The Drosophila fragile x gene negatively regulates neuronal elaboration and synaptic differentiation. Curr. Biol. 2004, 14:1863-1870.
-
(2004)
Curr. Biol.
, vol.14
, pp. 1863-1870
-
-
Pan, L.1
Zhang, Y.Q.2
Woodruff, E.3
Broadie, K.4
-
115
-
-
77957678816
-
Open-label add-on treatment trial of minocycline in fragile X syndrome
-
Paribello C., Tao L., Folino A., Berry-Kravis E., Tranfaglia M., Ethell I.M., Ethell D.W. Open-label add-on treatment trial of minocycline in fragile X syndrome. BMC Neurol. 2010, 10:91.
-
(2010)
BMC Neurol.
, vol.10
, pp. 91
-
-
Paribello, C.1
Tao, L.2
Folino, A.3
Berry-Kravis, E.4
Tranfaglia, M.5
Ethell, I.M.6
Ethell, D.W.7
-
116
-
-
79952060043
-
Genetic-background modulation of core and variable autistic-like symptoms in FMR1 knock-out mice
-
Pietropaolo S., Guilleminot A., Martin B., D'Amato F.R., Crusio W.E. Genetic-background modulation of core and variable autistic-like symptoms in FMR1 knock-out mice. PLoS ONE 2011, 6:e17073.
-
(2011)
PLoS ONE
, vol.6
, pp. e17073
-
-
Pietropaolo, S.1
Guilleminot, A.2
Martin, B.3
D'Amato, F.R.4
Crusio, W.E.5
-
117
-
-
84856437186
-
Which comes first in fragile X syndrome, dendritic spine dysgenesis or defects in circuit plasticity?
-
Portera-Cailliau C. Which comes first in fragile X syndrome, dendritic spine dysgenesis or defects in circuit plasticity?. Neuroscientist 2011, 18:28-44.
-
(2011)
Neuroscientist
, vol.18
, pp. 28-44
-
-
Portera-Cailliau, C.1
-
118
-
-
0024992330
-
Study of WAIS-R Quick Test and PPVT IQS for neuropsychiatric patients
-
Price D.R., Herbert D.A., Walsh M.L., Law J.G. Study of WAIS-R Quick Test and PPVT IQS for neuropsychiatric patients. Percept. Mot. Skills 1990, 70:1320-1322.
-
(1990)
Percept. Mot. Skills
, vol.70
, pp. 1320-1322
-
-
Price, D.R.1
Herbert, D.A.2
Walsh, M.L.3
Law, J.G.4
-
119
-
-
0016251748
-
Dendritic spine dysgenesis and mental retardation
-
Purpura R.P. Dendritic spine dysgenesis and mental retardation. Science 1974, 186:1126-1128.
-
(1974)
Science
, vol.186
, pp. 1126-1128
-
-
Purpura, R.P.1
-
120
-
-
84876416347
-
Altered cerebral protein synthesis in fragile X syndrome: studies in human subjects and knockout mice
-
Qin M., Schmidt K.C., Zametkin A.J., Bishu S., Horowitz L.M., Burlin T.V., Xia Z., Huang T., Quezado Z.M., Smith C.B. Altered cerebral protein synthesis in fragile X syndrome: studies in human subjects and knockout mice. J. Cereb. Blood Flow Metab. 2013, 33:499-507.
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, pp. 499-507
-
-
Qin, M.1
Schmidt, K.C.2
Zametkin, A.J.3
Bishu, S.4
Horowitz, L.M.5
Burlin, T.V.6
Xia, Z.7
Huang, T.8
Quezado, Z.M.9
Smith, C.B.10
-
121
-
-
0031767811
-
The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity
-
Randolph C., Tierney M.C., Mohr E., Chase T.N. The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS): preliminary clinical validity. J. Clin. Exp. Neuropsychol. 1998, 20:310-319.
-
(1998)
J. Clin. Exp. Neuropsychol.
, vol.20
, pp. 310-319
-
-
Randolph, C.1
Tierney, M.C.2
Mohr, E.3
Chase, T.N.4
-
122
-
-
0037417238
-
Memantine in moderate-to-severe Alzheimer's disease
-
Reisberg B., Doody R., Stoffler A., Schmitt F., Ferris S., Mobius H.J., Memantine Study G. Memantine in moderate-to-severe Alzheimer's disease. N. Engl. J. Med. 2003, 348:1333-1341.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1333-1341
-
-
Reisberg, B.1
Doody, R.2
Stoffler, A.3
Schmitt, F.4
Ferris, S.5
Mobius, H.J.6
Memantine Study, G.7
-
123
-
-
0028898302
-
Neurodevelopmental effects of the FMR-1 full mutation in humans
-
Reiss A.L., Abrams M.T., Greenlaw R., Freund L., Denckla M.B. Neurodevelopmental effects of the FMR-1 full mutation in humans. Nat. Med. 1995, 1:159-167.
-
(1995)
Nat. Med.
, vol.1
, pp. 159-167
-
-
Reiss, A.L.1
Abrams, M.T.2
Greenlaw, R.3
Freund, L.4
Denckla, M.B.5
-
124
-
-
33644677918
-
Performance on the PPVT-III and the EVT: applicability of the measures with African American and European American preschool children
-
Restrepo M.A., Schwanenflugel P.J., Blake J., Neuharth-Pritchett S., Cramer S.E., Ruston H.P. Performance on the PPVT-III and the EVT: applicability of the measures with African American and European American preschool children. Lang. Speech Hear Serv. Sch. 2006, 37:17-27.
-
(2006)
Lang. Speech Hear Serv. Sch.
, vol.37
, pp. 17-27
-
-
Restrepo, M.A.1
Schwanenflugel, P.J.2
Blake, J.3
Neuharth-Pritchett, S.4
Cramer, S.E.5
Ruston, H.P.6
-
125
-
-
58149485508
-
Making synaptic plasticity and memory last: mechanisms of translational regulation
-
Richter J.D., Klann E. Making synaptic plasticity and memory last: mechanisms of translational regulation. Genes Dev. 2009, 23:1-11.
-
(2009)
Genes Dev.
, vol.23
, pp. 1-11
-
-
Richter, J.D.1
Klann, E.2
-
126
-
-
0021837533
-
Adult fragile X syndrome. Clinico-neuropathologic findings
-
Rudelli R.D., Brown W.T., Wisniewski K., Jenkins E.C., Laure-Kamionowska M., Connell F., Wisniewski H.M. Adult fragile X syndrome. Clinico-neuropathologic findings. Acta Neuropathol. 1985, 67:289-295.
-
(1985)
Acta Neuropathol.
, vol.67
, pp. 289-295
-
-
Rudelli, R.D.1
Brown, W.T.2
Wisniewski, K.3
Jenkins, E.C.4
Laure-Kamionowska, M.5
Connell, F.6
Wisniewski, H.M.7
-
127
-
-
84863875429
-
Psychometric study of the aberrant behavior checklist in fragile X syndrome and implications for targeted treatment
-
Sansone S.M., Widaman K.F., Hall S.S., Reiss A.L., Lightbody A., Kaufmann W.E., Berry-Kravis E., Lachiewicz A., Brown E.C., Hessl D. Psychometric study of the aberrant behavior checklist in fragile X syndrome and implications for targeted treatment. J. Autism Dev. Disord. 2012, 42:1377-1392.
-
(2012)
J. Autism Dev. Disord.
, vol.42
, pp. 1377-1392
-
-
Sansone, S.M.1
Widaman, K.F.2
Hall, S.S.3
Reiss, A.L.4
Lightbody, A.5
Kaufmann, W.E.6
Berry-Kravis, E.7
Lachiewicz, A.8
Brown, E.C.9
Hessl, D.10
-
128
-
-
84885914618
-
Effectiveness and safety of donepezil in boys with fragile X syndrome: a double-blind, randomized, controlled pilot study
-
Sahu J.K., Gulati S., Sapra S., Arya R., Chauhan S., Chowdhury M.R., Gupta N., Kabra M., Gupta Y.K., Dwivedi S.N., Kalra V. Effectiveness and safety of donepezil in boys with fragile X syndrome: a double-blind, randomized, controlled pilot study. J. Child. Neurol. 2013, 28:570-575.
-
(2013)
J. Child. Neurol.
, vol.28
, pp. 570-575
-
-
Sahu, J.K.1
Gulati, S.2
Sapra, S.3
Arya, R.4
Chauhan, S.5
Chowdhury, M.R.6
Gupta, N.7
Kabra, M.8
Gupta, Y.K.9
Dwivedi, S.N.10
Kalra, V.11
-
129
-
-
33748431414
-
Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders
-
Scahill L., McDougle C.J., Williams S.K., Dimitropoulos A., Aman M.G., McCracken J.T., Tierney E., Arnold L.E., Cronin P., Grados M., Ghuman J., Koenig K., Lam K.S., McGough J., Posey D.J., Ritz L., Swiezy N.B., Vitiello B., Research Units on Pediatric Psychopharmacology Autism N. Children's Yale-Brown Obsessive Compulsive Scale modified for pervasive developmental disorders. J. Am. Acad. Child Adolesc. Psychiatry 2006, 45:1114-1123.
-
(2006)
J. Am. Acad. Child Adolesc. Psychiatry
, vol.45
, pp. 1114-1123
-
-
Scahill, L.1
McDougle, C.J.2
Williams, S.K.3
Dimitropoulos, A.4
Aman, M.G.5
McCracken, J.T.6
Tierney, E.7
Arnold, L.E.8
Cronin, P.9
Grados, M.10
Ghuman, J.11
Koenig, K.12
Lam, K.S.13
McGough, J.14
Posey, D.J.15
Ritz, L.16
Swiezy, N.B.17
Vitiello, B.18
-
130
-
-
0029586063
-
Adult fragile X syndrome: neuropsychology, brain anatomy, and metabolism
-
Schapiro M.B., Murphy D.G.M., Hagerman R.J., Azari N.P., Alexander G.E., Miezejeski C.M., Hinton V.J., Horwitz B., Haxby J.V., Kumar A., White B., Grady C.L. Adult fragile X syndrome: neuropsychology, brain anatomy, and metabolism. Am. J. Med. Genet. 1995, 60:480-493.
-
(1995)
Am. J. Med. Genet.
, vol.60
, pp. 480-493
-
-
Schapiro, M.B.1
Murphy, D.G.M.2
Hagerman, R.J.3
Azari, N.P.4
Alexander, G.E.5
Miezejeski, C.M.6
Hinton, V.J.7
Horwitz, B.8
Haxby, J.V.9
Kumar, A.10
White, B.11
Grady, C.L.12
-
131
-
-
70350022707
-
Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities
-
Schutt J., Falley K., Richter D., Kreienkamp H.J., Kindler S. Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities. J. Biol. Chem. 2009, 284:25479-25487.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 25479-25487
-
-
Schutt, J.1
Falley, K.2
Richter, D.3
Kreienkamp, H.J.4
Kindler, S.5
-
132
-
-
74949102875
-
Dysregulation of mTOR signaling in fragile X syndrome
-
Sharma A., Hoeffer C.A., Takayasu Y., Miyawaki T., McBride S.M., Klann E., Zukin R.S. Dysregulation of mTOR signaling in fragile X syndrome. J. Neurosci. 2010, 30:694-702.
-
(2010)
J. Neurosci.
, vol.30
, pp. 694-702
-
-
Sharma, A.1
Hoeffer, C.A.2
Takayasu, Y.3
Miyawaki, T.4
McBride, S.M.5
Klann, E.6
Zukin, R.S.7
-
133
-
-
80053948646
-
Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile x syndrome
-
Sheridan S.D., Theriault K.M., Reis S.A., Zhou F., Madison J.M., Daheron L., Loring J.F., Haggarty S.J. Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile x syndrome. PLoS ONE 2011, 6:e26203.
-
(2011)
PLoS ONE
, vol.6
, pp. e26203
-
-
Sheridan, S.D.1
Theriault, K.M.2
Reis, S.A.3
Zhou, F.4
Madison, J.M.5
Daheron, L.6
Loring, J.F.7
Haggarty, S.J.8
-
134
-
-
52949098297
-
Savings and extinction of conditioned eyeblink responses in fragile X syndrome
-
Smit A.E., van der Geest J.N., Vellema M., Koekkoek B., Willemsen R., Govaerts L.C., Oostra B.A., De Zeeuw C.I., Vanderwerf F. Savings and extinction of conditioned eyeblink responses in fragile X syndrome. Genes Brain Behav. 2008, 7:770-777.
-
(2008)
Genes Brain Behav.
, vol.7
, pp. 770-777
-
-
Smit, A.E.1
van der Geest, J.N.2
Vellema, M.3
Koekkoek, B.4
Willemsen, R.5
Govaerts, L.C.6
Oostra, B.A.7
De Zeeuw, C.I.8
Vanderwerf, F.9
-
135
-
-
34147207042
-
Receptor-specific inhibition of GABAB-activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus
-
Sohn J.W., Lee D., Cho H., Lim W., Shin H.S., Lee S.H., Ho W.K. Receptor-specific inhibition of GABAB-activated K+ currents by muscarinic and metabotropic glutamate receptors in immature rat hippocampus. J. Physiol. 2007, 580:411-422.
-
(2007)
J. Physiol.
, vol.580
, pp. 411-422
-
-
Sohn, J.W.1
Lee, D.2
Cho, H.3
Lim, W.4
Shin, H.S.5
Lee, S.H.6
Ho, W.K.7
-
136
-
-
0022080849
-
Diagnostic uses of the Vineland Adaptive Behavior Scales
-
Sparrow S.S., Cicchetti D.V. Diagnostic uses of the Vineland Adaptive Behavior Scales. J. Pediatr. Psychol. 1985, 10:215-225.
-
(1985)
J. Pediatr. Psychol.
, vol.10
, pp. 215-225
-
-
Sparrow, S.S.1
Cicchetti, D.V.2
-
137
-
-
79951567150
-
Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses
-
Spencer C.M., Alekseyenko O., Hamilton S.M., Thomas A.M., Serysheva E., Yuva-Paylor L.A., Paylor R. Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses. Autism Res 2011, 4:40-56.
-
(2011)
Autism Res
, vol.4
, pp. 40-56
-
-
Spencer, C.M.1
Alekseyenko, O.2
Hamilton, S.M.3
Thomas, A.M.4
Serysheva, E.5
Yuva-Paylor, L.A.6
Paylor, R.7
-
138
-
-
26444548563
-
Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome
-
Spencer C.M., Alekseyenko O., Serysheva E., Yuva-Paylor L.A., Paylor R. Altered anxiety-related and social behaviors in the Fmr1 knockout mouse model of fragile X syndrome. Genes Brain Behav. 2005, 4:420-430.
-
(2005)
Genes Brain Behav.
, vol.4
, pp. 420-430
-
-
Spencer, C.M.1
Alekseyenko, O.2
Serysheva, E.3
Yuva-Paylor, L.A.4
Paylor, R.5
-
139
-
-
79955625469
-
Early continuous inhibition of group 1 mGlu signaling partially rescues dendritic spine abnormalities in the Fmr1 knockout mouse model for fragile X syndrome
-
Su T., Fan H.X., Jiang T., Sun W.W., Den W.Y., Gao M.M., Chen S.Q., Zhao Q.H., Yi Y.H. Early continuous inhibition of group 1 mGlu signaling partially rescues dendritic spine abnormalities in the Fmr1 knockout mouse model for fragile X syndrome. Psychopharmacology (Berl) 2010, 215:291-300.
-
(2010)
Psychopharmacology (Berl)
, vol.215
, pp. 291-300
-
-
Su, T.1
Fan, H.X.2
Jiang, T.3
Sun, W.W.4
Den, W.Y.5
Gao, M.M.6
Chen, S.Q.7
Zhao, Q.H.8
Yi, Y.H.9
-
140
-
-
0017381277
-
Fragile sites on human chromosomes: demonstration of their dependence on the type of tissue culture medium
-
Sutherland G.R. Fragile sites on human chromosomes: demonstration of their dependence on the type of tissue culture medium. Science 1977, 197:265-266.
-
(1977)
Science
, vol.197
, pp. 265-266
-
-
Sutherland, G.R.1
-
141
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
142
-
-
84860473697
-
Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome
-
Till S.M., Wijetunge L.S., Seidel V.G., Harlow E., Wright A.K., Bagni C., Contractor A., Gillingwater T.H., Kind P.C. Altered maturation of the primary somatosensory cortex in a mouse model of fragile X syndrome. Hum. Mol. Genet. 2012, 21:2143-2156.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2143-2156
-
-
Till, S.M.1
Wijetunge, L.S.2
Seidel, V.G.3
Harlow, E.4
Wright, A.K.5
Bagni, C.6
Contractor, A.7
Gillingwater, T.H.8
Kind, P.C.9
-
143
-
-
77952785513
-
Treatment with valproic acid ameliorates ADHD symptoms in fragile X syndrome boys
-
Torrioli M., Vernacotola S., Setini C., Bevilacqua F., Martinelli D., Snape M., Hutchison J.A., Di Raimo F.R., Tabolacci E., Neri G. Treatment with valproic acid ameliorates ADHD symptoms in fragile X syndrome boys. Am. J. Med. Genet. A 2010, 152A:1420-1427.
-
(2010)
Am. J. Med. Genet. A
, vol.152 A
, pp. 1420-1427
-
-
Torrioli, M.1
Vernacotola, S.2
Setini, C.3
Bevilacqua, F.4
Martinelli, D.5
Snape, M.6
Hutchison, J.A.7
Di Raimo, F.R.8
Tabolacci, E.9
Neri, G.10
-
144
-
-
83055181288
-
The psychiatric presentation of fragile X: evolution of the diagnosis and treatment of the psychiatric comorbidities of fragile X syndrome
-
Tranfaglia M.R. The psychiatric presentation of fragile X: evolution of the diagnosis and treatment of the psychiatric comorbidities of fragile X syndrome. Dev. Neurosci. 2011, 33:337-348.
-
(2011)
Dev. Neurosci.
, vol.33
, pp. 337-348
-
-
Tranfaglia, M.R.1
-
145
-
-
8644255888
-
Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships
-
Tucker B., Richards R., Lardelli M. Expression of three zebrafish orthologs of human FMR1-related genes and their phylogenetic relationships. Dev. Genes Evol. 2004, 214:567-574.
-
(2004)
Dev. Genes Evol.
, vol.214
, pp. 567-574
-
-
Tucker, B.1
Richards, R.2
Lardelli, M.3
-
146
-
-
33751353757
-
Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome
-
Tucker B., Richards R.I., Lardelli M. Contribution of mGluR and Fmr1 functional pathways to neurite morphogenesis, craniofacial development and fragile X syndrome. Hum. Mol. Genet. 2006, 15:3446-3458.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 3446-3458
-
-
Tucker, B.1
Richards, R.I.2
Lardelli, M.3
-
147
-
-
77956214743
-
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
-
Urbach A., Bar-Nur O., Daley G.Q., Benvenisty N. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 2010, 6:407-411.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 407-411
-
-
Urbach, A.1
Bar-Nur, O.2
Daley, G.Q.3
Benvenisty, N.4
-
148
-
-
77958192422
-
Side effects of minocycline treatment in patients with fragile x syndrome and exploration of outcome measures
-
Utari A., Chonchaiya W., Rivera S.M., Schneider A., Hagerman R.J., Faradz S.M., Ethell I.M., Nguyen D.V. Side effects of minocycline treatment in patients with fragile x syndrome and exploration of outcome measures. Am. J. Intellect. Dev. Disabil. 2010, 115:433-443.
-
(2010)
Am. J. Intellect. Dev. Disabil.
, vol.115
, pp. 433-443
-
-
Utari, A.1
Chonchaiya, W.2
Rivera, S.M.3
Schneider, A.4
Hagerman, R.J.5
Faradz, S.M.6
Ethell, I.M.7
Nguyen, D.V.8
-
149
-
-
17544376890
-
Characterisation of Fmrp in zebrafish: evolutionary dynamics of the fmr1 gene
-
van't Padje S., Engels B., Blonden L., Severijnen L.A., Verheijen F., Oostra B.A., Willemsen R. Characterisation of Fmrp in zebrafish: evolutionary dynamics of the fmr1 gene. Dev. Genes Evol. 2005, 215:198-206.
-
(2005)
Dev. Genes Evol.
, vol.215
, pp. 198-206
-
-
van't Padje, S.1
Engels, B.2
Blonden, L.3
Severijnen, L.A.4
Verheijen, F.5
Oostra, B.A.6
Willemsen, R.7
-
150
-
-
80053611552
-
Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome
-
Veeraragavan S., Bui N., Perkins J.R., Yuva-Paylor L.A., Carpenter R.L., Paylor R. Modulation of behavioral phenotypes by a muscarinic M1 antagonist in a mouse model of fragile X syndrome. Psychopharmacology (Berl) 2011, 217:143-151.
-
(2011)
Psychopharmacology (Berl)
, vol.217
, pp. 143-151
-
-
Veeraragavan, S.1
Bui, N.2
Perkins, J.R.3
Yuva-Paylor, L.A.4
Carpenter, R.L.5
Paylor, R.6
-
151
-
-
80053607529
-
The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide
-
Veeraragavan S., Bui N., Perkins J.R., Yuva-Paylor L.A., Paylor R. The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide. Behav. Neurosci. 2011, 125:783-790.
-
(2011)
Behav. Neurosci.
, vol.125
, pp. 783-790
-
-
Veeraragavan, S.1
Bui, N.2
Perkins, J.R.3
Yuva-Paylor, L.A.4
Paylor, R.5
-
152
-
-
80053924976
-
Genetic reduction of muscarinic M(4) receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS)
-
Veeraragavan S., Graham D., Bui N., Yuva-Paylor L.A., Wess J., Paylor R. Genetic reduction of muscarinic M(4) receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS). Behav. Brain Res. 2011, 223:310-321.
-
(2011)
Behav. Brain Res.
, vol.223
, pp. 310-321
-
-
Veeraragavan, S.1
Graham, D.2
Bui, N.3
Yuva-Paylor, L.A.4
Wess, J.5
Paylor, R.6
-
153
-
-
0025905795
-
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
-
Verkerk A.J., Pieretti M., Sutcliffe J.S., Fu Y.H., Kuhl D.P., Pizzuti A., Reiner O., Richards S., Victoria M.F., Zhang F.P., Eussen B.E., Van Ommen G.J.B., Blonden L.A.J., Riggins G.J., Chastain J.L., Kunst C.B., Galjaard H., Caskey C.T., Nelson D.L., Oostra B.A., Warren S.T. Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 1991, 65:905-914.
-
(1991)
Cell
, vol.65
, pp. 905-914
-
-
Verkerk, A.J.1
Pieretti, M.2
Sutcliffe, J.S.3
Fu, Y.H.4
Kuhl, D.P.5
Pizzuti, A.6
Reiner, O.7
Richards, S.8
Victoria, M.F.9
Zhang, F.P.10
Eussen, B.E.11
Van Ommen, G.J.B.12
Blonden, L.A.J.13
Riggins, G.J.14
Chastain, J.L.15
Kunst, C.B.16
Galjaard, H.17
Caskey, C.T.18
Nelson, D.L.19
Oostra, B.A.20
Warren, S.T.21
more..
-
154
-
-
77954368724
-
Roles of FMRP in dopaminergic stimulation induced synapse-associated protein synthesis and subsequent AMPA receptor internalization
-
Wang H., Kim S.S., Zhuo M. Roles of FMRP in dopaminergic stimulation induced synapse-associated protein synthesis and subsequent AMPA receptor internalization. J. Biol. Chem. 2010, 285:21888-21901.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 21888-21901
-
-
Wang, H.1
Kim, S.S.2
Zhuo, M.3
-
155
-
-
77954915376
-
Fragile X: leading the way for targeted treatments in autism
-
Wang L.W., Berry-Kravis E., Hagerman R.J. Fragile X: leading the way for targeted treatments in autism. Neurotherapeutics 2010, 7:264-274.
-
(2010)
Neurotherapeutics
, vol.7
, pp. 264-274
-
-
Wang, L.W.1
Berry-Kravis, E.2
Hagerman, R.J.3
-
156
-
-
84859780333
-
Activation of the ERK pathway contributes to the behavioral deficit of fragile X-syndrome
-
Wang X., Snape M., Klann E., Stone J.G., Singh A., Petersen R.B., Castellani R.J., Casadesus G., Smith M.A., Zhu X. Activation of the ERK pathway contributes to the behavioral deficit of fragile X-syndrome. J. Neurochem. 2012, 121:672-679.
-
(2012)
J. Neurochem.
, vol.121
, pp. 672-679
-
-
Wang, X.1
Snape, M.2
Klann, E.3
Stone, J.G.4
Singh, A.5
Petersen, R.B.6
Castellani, R.J.7
Casadesus, G.8
Smith, M.A.9
Zhu, X.10
-
157
-
-
84859780333
-
Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome
-
Wang X., Snape M., Klann E., Stone J.G., Singh A., Petersen R.B., Castellani R.J., Casadesus G., Smith M.A., Zhu X. Activation of the extracellular signal-regulated kinase pathway contributes to the behavioral deficit of fragile x-syndrome. J. Neurochem. 2012, 121:672-679.
-
(2012)
J. Neurochem.
, vol.121
, pp. 672-679
-
-
Wang, X.1
Snape, M.2
Klann, E.3
Stone, J.G.4
Singh, A.5
Petersen, R.B.6
Castellani, R.J.7
Casadesus, G.8
Smith, M.A.9
Zhu, X.10
-
158
-
-
84872031387
-
The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome
-
Wei H., Dobkin C., Sheikh A.M., Malik M., Brown W.T., Li X. The therapeutic effect of memantine through the stimulation of synapse formation and dendritic spine maturation in autism and fragile X syndrome. PLoS ONE 2012, 7:e36981.
-
(2012)
PLoS ONE
, vol.7
, pp. e36981
-
-
Wei, H.1
Dobkin, C.2
Sheikh, A.M.3
Malik, M.4
Brown, W.T.5
Li, X.6
-
159
-
-
0345528532
-
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
-
Weiler I.J., Irwin S.A., Klintsova A.Y., Spencer C.M., Brazelton A.D., Miyashiro K., Comery T.A., Patel B., Eberwine J., Greenough W.T. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:5395-5400.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 5395-5400
-
-
Weiler, I.J.1
Irwin, S.A.2
Klintsova, A.Y.3
Spencer, C.M.4
Brazelton, A.D.5
Miyashiro, K.6
Comery, T.A.7
Patel, B.8
Eberwine, J.9
Greenough, W.T.10
-
160
-
-
55349098271
-
Early-phase ERK activation as a biomarker for metabolic status in fragile X syndrome
-
Weng N., Weiler I.J., Sumis A., Berry-Kravis E., Greenough W.T. Early-phase ERK activation as a biomarker for metabolic status in fragile X syndrome. Am. J. Med. Genet. B: Neuropsychiatr. Genet. 2008, 147B:1253-1257.
-
(2008)
Am. J. Med. Genet. B: Neuropsychiatr. Genet.
, vol.147 B
, pp. 1253-1257
-
-
Weng, N.1
Weiler, I.J.2
Sumis, A.3
Berry-Kravis, E.4
Greenough, W.T.5
-
161
-
-
0030570761
-
Association of FMRP with ribosomal precursor particles in the nucleolus
-
Willemsen R., Bontekoe C., Tamanini F., Galjaard H., Hoogeveen A.T., Oostra B.A. Association of FMRP with ribosomal precursor particles in the nucleolus. Biochem. Biophys. Res. Commun. 1996, 225:27-33.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.225
, pp. 27-33
-
-
Willemsen, R.1
Bontekoe, C.2
Tamanini, F.3
Galjaard, H.4
Hoogeveen, A.T.5
Oostra, B.A.6
-
162
-
-
0036626521
-
Timing of the absence of FMR1 expression in full mutation chorionic villi
-
Willemsen R., Bontekoe C.J., Severijnen L.A., Oostra B.A. Timing of the absence of FMR1 expression in full mutation chorionic villi. Hum. Genet. 2002, 110:601-605.
-
(2002)
Hum. Genet.
, vol.110
, pp. 601-605
-
-
Willemsen, R.1
Bontekoe, C.J.2
Severijnen, L.A.3
Oostra, B.A.4
-
163
-
-
71549145629
-
Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome
-
Yuskaitis C.J., Mines M.A., King M.K., Sweatt J.D., Miller C.A., Jope R.S. Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of fragile X syndrome. Biochem. Pharmacol. 2010, 79:632-646.
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 632-646
-
-
Yuskaitis, C.J.1
Mines, M.A.2
King, M.K.3
Sweatt, J.D.4
Miller, C.A.5
Jope, R.S.6
-
164
-
-
34247485947
-
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
-
Zalfa F., Eleuteri B., Dickson K.S., Mercaldo V., De Rubeis S., di Penta A., Tabolacci E., Chiurazzi P., Neri G., Grant S.G., Bagni C. A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat. Neurosci. 2007, 10:578-587.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 578-587
-
-
Zalfa, F.1
Eleuteri, B.2
Dickson, K.S.3
Mercaldo, V.4
De Rubeis, S.5
di Penta, A.6
Tabolacci, E.7
Chiurazzi, P.8
Neri, G.9
Grant, S.G.10
Bagni, C.11
-
165
-
-
74249093220
-
A mouse model of the human fragile X syndrome I304N mutation
-
Zang J.B., Nosyreva E.D., Spencer C.M., Volk L.J., Musunuru K., Zhong R., Stone E.F., Yuva-Paylor L.A., Huber K.M., Paylor R., Darnell J.C., Darnell R.B. A mouse model of the human fragile X syndrome I304N mutation. PLoS Genet. 2009, 5:e1000758.
-
(2009)
PLoS Genet.
, vol.5
, pp. e1000758
-
-
Zang, J.B.1
Nosyreva, E.D.2
Spencer, C.M.3
Volk, L.J.4
Musunuru, K.5
Zhong, R.6
Stone, E.F.7
Yuva-Paylor, L.A.8
Huber, K.M.9
Paylor, R.10
Darnell, J.C.11
Darnell, R.B.12
-
166
-
-
77955641542
-
Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells
-
Zeng H., Guo M., Martins-Taylor K., Wang X., Zhang Z., Park J.W., Zhan S., Kronenberg M.S., Lichtler A., Liu H.X., Chen F.P., Yue L., Li X.J., Xu R.H. Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells. PLoS ONE 2010, 5:e11853.
-
(2010)
PLoS ONE
, vol.5
, pp. e11853
-
-
Zeng, H.1
Guo, M.2
Martins-Taylor, K.3
Wang, X.4
Zhang, Z.5
Park, J.W.6
Zhan, S.7
Kronenberg, M.S.8
Lichtler, A.9
Liu, H.X.10
Chen, F.P.11
Yue, L.12
Li, X.J.13
Xu, R.H.14
-
167
-
-
0035977134
-
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function
-
Zhang Y.Q., Bailey A.M., Matthies H.J., Renden R.B., Smith M.A., Speese S.D., Rubin G.M., Broadie K. Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell 2001, 107:591-603.
-
(2001)
Cell
, vol.107
, pp. 591-603
-
-
Zhang, Y.Q.1
Bailey, A.M.2
Matthies, H.J.3
Renden, R.B.4
Smith, M.A.5
Speese, S.D.6
Rubin, G.M.7
Broadie, K.8
-
168
-
-
29544451200
-
ADHD Rating Scale IV: psychometric properties from a multinational study as a clinician-administered instrument
-
Zhang S., Faries D.E., Vowles M., Michelson D. ADHD Rating Scale IV: psychometric properties from a multinational study as a clinician-administered instrument. Int. J. Methods Psychiatr. Res. 2005, 14:186-201.
-
(2005)
Int. J. Methods Psychiatr. Res.
, vol.14
, pp. 186-201
-
-
Zhang, S.1
Faries, D.E.2
Vowles, M.3
Michelson, D.4
|