Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model

Genes, Brain and Behavior

Volumn 11, Issue 5, 2012, Pages 586-600

  Goebel Goody, S M ^a,b   Wilson Wallis, E D ^a   Royston, S ^b   Tagliatela, S M ^b   Naegele, J R ^b   Lombroso, P J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WESLEYAN UNIVERSITY   (United States)

Author keywords

Anxiety; Audiogenic seizures; Behavior; C Fos; Fragile X syndrome; Social; STEP; Tyrosine phosphatase

Indexed keywords

METABOTROPIC RECEPTOR; PROTEIN C FOS; PROTEIN TYROSINE PHOSPHATASE; STRIATAL ENRICHED PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIOR DISORDER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; FRAGILE X SYNDROME; GENETIC MANIPULATION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SOCIAL DISABILITY; SOCIAL DOMINANCE;

ANIMALS; BEHAVIOR, ANIMAL; CHOICE BEHAVIOR; DISEASE MODELS, ANIMAL; FRAGILE X MENTAL RETARDATION PROTEIN; HIPPOCAMPUS; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURONS; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, METABOTROPIC GLUTAMATE; SOCIAL DOMINANCE; SYNAPTOSOMES;

MUS;

EID: 84863333644     PISSN: 16011848     EISSN: 1601183X     Source Type: Journal    
DOI: 10.1111/j.1601-183X.2012.00781.x     Document Type: Article

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